Title: Book the Best Chillicothe LUXURY Hotels - Upscale Hotels in Chillicothe, OH | Expedia.ca [Hotels in Chillicothe](https://expedia.ca/Chillicothe-Hotels.d6059576.Travel-Guide-Hotels)[Vacation Rentals in Chillicothe](https://expedia.ca/Chillicothe-Vacation-Rentals.d6059576.Travel-Guide-VacationRentals)[Flights to Chillicothe](https://expedia.ca/Cheap-Flights-To-Chillicothe.d6059576.Travel-Guide-Flights)[Chillicothe Car Rentals](https://expedia.ca/Car-Rentals-In-Chillicothe.d6059576.Car-Rental-Guide)[Chillicothe Vacation Packages](https://expedia.ca/Chillicothe.d6059576.Destination-Travel-Guides) ![Nope, not a golf course, this is a shot of Mound City. A collection of 22 earthen mounds of varying heights and sizes made by the Hopewell Indians over 2000 years ago. The mounds were threatened by the construction of Camp Sherman in 1917 to train troops for WWI. Today the site is managed by the National Park Services.](https://images.trvl-media.com/place/6087351/bcfd28ab-2232-45aa-bfc6-2ce26d5073d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by throwingsofas # Find luxury hotels in Chillicothe, OH - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Chillicothe Luxury Hotels Tonight [Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=6059576&startDate=2025-12-04&endDate=2025-12-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 5 - Dec 6](https://www.expedia.ca/Hotel-Search?regionId=6059576&startDate=2025-12-05&endDate=2025-12-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6059576&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6059576&startDate=2025-12-12&endDate=2025-12-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Chillicothe Luxury Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/9618bbe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking, Refrigerator & Microwave | Living area](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/c5484f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/b78b83f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/8b407aef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Adena Inn Chillicothe 7.8/10 Good (772) "Several restaurants to walk to" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $142 CA $163 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Chillicothe-Hotels-Best-Western-Adena-Inn.h8583.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/752fe927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/c13080ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/57dcd066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/09076694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Executive Inn Chillicothe 7.6/10 Good (642) "Great room, clean and beds and pillows super comfy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $86 CA $99 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Chillicothe-Hotels-Executive-Inn.h13068101.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/50c4cecb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/fb22d150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corporate Suite](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/f7589ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corporate Suite](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/4bd86eee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Christopher Inn and Suites Chillicothe 9.0/10 Wonderful (1112) "We have stayed here several times and it is always a great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $173 CA $199 total includes taxes & fees Dec 13 - Dec 14 [](https://www.expedia.ca/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/1000/906/3fbd3ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1000/906/db38e60d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/1000/906/02b08c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1000/906/3ce9095e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Chillicothe Chillicothe 6.0/10 (135) "Our room had mold in refrigerator and our sheets was filthiest ever" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Violet [](https://www.expedia.ca/Chillicothe-Hotels-Americas-Best-Value-Inn-Chillicothe.h906.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-18&endDate=2025-12-19®ionId=6059576&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Chillicothe ### Chillicotheand its attractions for luxury travelers Chillicothe, Ohio, offers a unique blend of historical charm and modern luxury, perfect for discerning travellers. Begin your exploration at the stunning Adena Mansion and Gardens, the elegant former home of Ohio's first governor, where you can stroll through beautifully landscaped grounds and revel in the rich history. Next, immerse yourself in the vibrant art scene at the Pump House Centre for the Arts, where local exhibitions showcase the talents of regional artists, providing a cultural touchpoint. For a taste of the outdoors, the nearby Scioto Trail State Park presents scenic hiking opportunities, with trails that wind through picturesque landscapes, ideal for a serene escape. Don't miss the Ross County Heritage Centre, where interactive exhibits highlight the region's past, offering insights into the area’s fascinating history. Finally, indulge in gourmet dining at local establishments such as the renowned The Pour House, known for its locally sourced menu and exquisite wine selection. When it comes to accommodation, the upscale hotels in the downtown area offer modern amenities and attentive service, ensuring a pampered stay amidst your adventures. With easy access to these points of interest, you can unwind in luxurious surroundings while enjoying the rich culture and beauty that Chillicothe has to offer. ## Top Chillicothe Hotel Reviews ![Hyatt Place Columbus/OSU](https://images.trvl-media.com/lodging/4000000/3780000/3775700/3775614/dc933531_y.jpg) ### Hyatt Place Columbus/OSU 10/10 Excellent "I would absolutely stay here again. The hotel was clean and the staff was welcoming. The room was spacious and well laid out. A desk area, a coffee bar with fridge and a well appointed lounging area. The beds were super comfortable and the shower had hot water with plenty of pressure. The surrounding area was quiet and peaceful with nearby dining options." [](https://expedia.ca/Columbus-Hotels-Hyatt-Place-ColumbusOSU.h3775614.Hotel-Information) ![Hyatt Regency Columbus](https://images.trvl-media.com/lodging/1000000/10000/2200/2200/7e9aa134_y.jpg) ### Hyatt Regency Columbus 10/10 Excellent "Nice Room Nice staff" [](https://expedia.ca/Columbus-Hotels-Hyatt-Regency-Columbus.h2200.Hotel-Information) ![Hilton Columbus at Easton](https://images.trvl-media.com/lodging/1000000/540000/533300/533205/a9a89076_y.jpg) ### Hilton Columbus at Easton 10/10 Excellent "The facilities were very nice and well kept. Close to plenty of food options and shopping places." [](https://expedia.ca/Columbus-Hotels-Hilton-Columbus-At-Easton.h533205.Hotel-Information) ![La Quinta Inn by Wyndham Columbus Airport Area](https://images.trvl-media.com/lodging/1000000/10000/6400/6340/2e9c7bab_y.jpg) ### La Quinta Inn by Wyndham Columbus Airport Area 10/10 Excellent "Perfect " [](https://expedia.ca/Columbus-Hotels-La-Quinta-Inn-By-Wyndham-Columbus-Airport-Area.h6340.Hotel-Information) ![Hilton Columbus Downtown](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270320/6a2e3c37_y.jpg) ### Hilton Columbus Downtown 10/10 Excellent "Clean room and great location. Staff was b Very friendly as well!" [](https://expedia.ca/Columbus-Hotels-Hilton-Columbus-Downtown.h5270320.Hotel-Information) ![The Blackwell Inn and Pfahl Conference Center](https://images.trvl-media.com/lodging/1000000/880000/876400/876317/13591420_y.jpg) ### The Blackwell Inn and Pfahl Conference Center 10/10 Excellent "The greatest hotel ever! The staff was super amazing and I will be staying again! My mom is here in the ICU and when I tell you the hotel was very informative because of the holiday they Uber’d me back in forth due to no shuttle it was truly a great week. Everyone needs a raise💗" [](https://expedia.ca/Columbus-Hotels-The-Blackwell-Inn-And-Pfahl-Conference-Center.h876317.Hotel-Information) ![Sonesta Columbus Downtown](https://images.trvl-media.com/lodging/1000000/30000/26900/26870/d5b1e434_y.jpg) ### Sonesta Columbus Downtown 10/10 Excellent "Great place very quiet. Very nice walk to the Nationwide Arena. The Vine+Forge had great staff they were very efficient! Would definitely recommend this hotel!" [](https://expedia.ca/Columbus-Hotels-Sonesta-Columbus.h26870.Hotel-Information) ![Red Roof Inn PLUS+ Columbus Downtown-Convention Center](https://images.trvl-media.com/lodging/1000000/210000/201000/200938/d6deb0a8_y.jpg) ### Red Roof Inn PLUS+ Columbus Downtown-Convention Center 10/10 Excellent "Everything was excellent " [](https://expedia.ca/Columbus-Hotels-Red-Roof-Inn-PLUS-Columbus-Downtown-Convention-Center.h200938.Hotel-Information) ![Days Inn by Wyndham Columbus East Airport](https://images.trvl-media.com/lodging/1000000/10000/4600/4541/49a8132f_y.jpg) ### Days Inn by Wyndham Columbus East Airport 10/10 Excellent "i was in a smoking room, which always makes me happy, even if i have to walk all the way round the back where our scent is out of the way. i have been contending with lots of very uncomfortable experiences lately because my physical and mental health are a struggle....deposits get sprung on me like threats and challenges....staff here was kind sa" [](https://expedia.ca/Columbus-Hotels-Days-Inn-By-Wyndham-Columbus-East-Airport.h4541.Hotel-Information) ## Frequently asked questions ### Are you looking for a luxury hotel for your stay in Chillicothe? ### When can I expect good weather in Chillicothe? ### What's there to see and do in Chillicothe? ## Explore a world of travel with Expedia - 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