Title: Guesthouse Charleston: SOUTH (105 A & B) - Latest Reviews, Deals & Photos 2025 - Expedia.ca [See all properties](http://www.expedia.ca/Hotel-Search?regionId=&adults=2&children=&sort=RECOMMENDED&useRewards=false&semdtl=&userIntent=&vip=false) Entire home # Guesthouse Charleston: SOUTH (105 A & B) Vacation home with kitchen, 6-minute walk to Medical University of South Carolina ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722667/c65e1538.jpg?impolicy=resizecrop&rw=598&ra=fit) ![Exterior](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722667/1e5527ab.jpg?impolicy=resizecrop&rw=297&ra=fit) ![8 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722667/16ddcd9d.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722667/67319217.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Smart TV](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722667/f2b3b5cf.jpg?impolicy=resizecrop&rw=297&ra=fit) - Overview - Amenities - Policies - Location Close to Medical University of South Carolina and College of Charleston, Guesthouse Charleston: SOUTH (105 A & B) provides a water park, laundry facilities, and more. Stay connected with in-room WiFi. 9.4 Exceptional ### Entire home 8 bedrooms9 bathroomsSleeps 203600 sq ft ## Popular amenities - Dryer - Washer - Barbecue grill - Kitchen - Parking available - Air conditioning ## Add dates for prices Check-in Check-out Travellers ## About this property ### Entire place You'll have the entire home to yourself and will only share it with other guests in your party. ### Guesthouse Charleston: SOUTH (105 A & B) Nestled peacefully on coveted Spring Street, this charming standalone duplex features eight spacious bedrooms and eight full bathrooms, just steps away from Cannon Green and just three blocks to historic King Street. Perfect for large groups or multi-family getaways, this two-unit home blends historic charm with modern luxury. As you step inside each unit, you'll be welcomed by an open kitchen, dining, and living area ideal for both entertaining and relaxing. Each of the eight bedrooms serves as a private retreat, offering ample space, large closets, and beautifully renovated en-suite bathrooms. Multiple outdoor living areas provide the perfect setting for al fresco dining, morning coffee, or unwinding as the sun sets over Charleston. Thoughtful details like hardwood floors throughout, flat-screen TVs in every bedroom and both living rooms, two additional half bathrooms, and two sets of washers and dryers make your stay comfortable and convenient. With four off-street parking spaces, high-speed Wi-Fi, and an unbeatable location in the vibrant Cannonborough/Elliotborough neighborhood, this home offers the ideal blend of space, style, and Southern charm. Permit # 105A OP2025-05681 Permit # 105B OP2024-04653 ## Property amenities ### Internet - Available in the house: WiFi ### Parking and transportation - Parking on site ### Kitchen - Coffee/tea maker - Cookware, dishware, and utensils - Dishwasher - Microwave - Oven - Refrigerator - Stovetop - Toaster ### Dining - Dining table ### Bedrooms - 8 bedrooms - Bedsheets provided ### Bathroom - 9 bathrooms - Hair dryer - Shower - Towels provided ### Living spaces - Dining table - Living room ### Entertainment - Smart TV ### Outdoor areas - Barbecue grill ### Laundry - Laundry facilities - Washing machine ### Comfort - Air conditioning - Heating ### Pets - No pets allowed ### Suitability/Accessibility - Smoking not allowed ### Services and conveniences - Iron/ironing board ### Location highlights - In the city center - Near a health/beauty spa - Near a hospital - Near an outlet shopping mall - Near the marina - Near the sea ### Things to do - Water park - Birdwatching nearby - Ecotours nearby - Horseback riding nearby - Motor boating nearby - Wildlife walks nearby ### Safety features - Carbon monoxide detector not reported (host has not indicated whether there is a carbon monoxide detector on the property; consider bringing a portable detector) - Smoke detector (host has indicated there is a smoke detector on the property) - First aid kit - Fire extinguisher - Deadbolt lock ### General - Unit size: 3,600 square feet ## Similar properties ![Terrace/patio](https://images.trvl-media.com/lodging/36000000/35850000/35844400/35844334/03dbd142.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Guesthouse Charleston: WEST (62 & 64) Downtown Charleston - Kitchen - Washer - Dryer - Free WiFi 10 Exceptional 55 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=35844334&PinnedHotelID=35844334&HadPinnedHotel=true®ionId=-1&adults=2) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722670/9484cc2f.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Guesthouse Charleston: SOUTH (82 A & B) Downtown Charleston - Kitchen - Washer - Dryer - Free WiFi 10 Exceptional 14 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=66722670&PinnedHotelID=66722670&HadPinnedHotel=true®ionId=-1&adults=2) ![Outdoor dining](https://images.trvl-media.com/lodging/35000000/34190000/34186600/34186584/5af7f4c4.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Guesthouse Charleston: WEST (242 B & C) Downtown Charleston - Kitchen - Washer - Dryer - Pet-friendly 10 Exceptional 28 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=34186584&PinnedHotelID=34186584&HadPinnedHotel=true®ionId=-1&adults=2) ![Terrace/patio](https://images.trvl-media.com/lodging/74000000/73350000/73346500/73346488/bb398fc7.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### THE INNS 8BR/6.5BA Downtown w Outdoor Space! Downtown Charleston - Kitchen - Air conditioning - Outdoor space - Parking available 9.8 Exceptional 16 reviews CA $435 CA $1,479 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-09&endDate=2025-12-10&selected=73346488&PinnedHotelID=73346488&HadPinnedHotel=true®ionId=-1&adults=2) ![Outdoor dining](https://images.trvl-media.com/lodging/97000000/96060000/96056400/96056332/w3824h2560x0y0-56ee8a04.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### The Lady Helène | 2 Blocks to King St Downtown Charleston - Pool - Kitchen - Washer - Dryer 9.2 Wonderful 5 reviews CA $1,067 CA $2,803 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13&selected=96056332&PinnedHotelID=96056332&HadPinnedHotel=true®ionId=-1&adults=2) ![Luxury Apartment | Living area](https://images.trvl-media.com/lodging/115000000/114410000/114401800/114401733/74bf505a.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Emerson Square Downtown Charleston - Kitchen - Parking included - Free WiFi - Air conditioning 10 Exceptional 1 review CA $291 CA $893 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01&selected=114401733&PinnedHotelID=114401733&HadPinnedHotel=true®ionId=-1&adults=2) ![Interior](https://images.trvl-media.com/lodging/67000000/66730000/66722700/66722668/1bcb9db5.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Guesthouse Charleston: SOUTH (105 ALL) Downtown Charleston - Kitchen - Washer - Dryer - Air conditioning 9.8 Exceptional 10 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=66722668&PinnedHotelID=66722668&HadPinnedHotel=true®ionId=-1&adults=2) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111640000/111634300/111634210/70472c6b.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### 8BR Downtown Luxury Escape Near King Downtown Charleston - Kitchen - Washer - Dryer - Air conditioning 9.6 Exceptional 5 reviews CA $522 CA $1,820 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-11&endDate=2025-11-12&selected=111634210&PinnedHotelID=111634210&HadPinnedHotel=true®ionId=-1&adults=2) ![Cookware/dishes/utensils](https://images.trvl-media.com/lodging/90000000/89870000/89865500/89865495/c262d02d.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Downtown Duplex - Spring St - Sleeps 26 Downtown Charleston - Kitchen - Washer - Dryer - Pet-friendly 10 Exceptional 2 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=89865495&PinnedHotelID=89865495&HadPinnedHotel=true®ionId=-1&adults=2) ![7 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/111000000/110390000/110385200/110385101/8ed0e8f9.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### The Gardenia House | Sleeps 15 | Multi-Unit Rental Downtown Charleston - Pool - Kitchen - Washer - Dryer 10 Exceptional 1 review [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=110385101&PinnedHotelID=110385101&HadPinnedHotel=true®ionId=-1&adults=2) ## Policies ### Check-in Check-in time starts at 4:00 PM Contactless check-in available Minimum check-in age: 21 ### Check-out Check-out before 10:00 AM ### Special check-in instructions You will receive an email from the host with check-in and check-out instructions ### Pets Pets not allowed ### Children and extra beds Children are welcome ### Events No events allowed ### Smoking Smoking is not permitted ## Important information ### You need to know Extra-person charges may apply and vary depending on property policy Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed Onsite parties or group events are strictly prohibited Host has not indicated whether there is a carbon monoxide detector on the property; consider bringing a portable detector with you on the trip Host has indicated there is a smoke detector on the property Safety features at this property include a fire extinguisher, a first aid kit, and a deadbolt lock This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation ### Property is also known as Vrbo Property Charleston South 105 A & B Guesthouse Charleston SOUTH (105 A/B) Guesthouse Charleston: SOUTH (105 A & B) Charleston Guesthouse Charleston: SOUTH (105 A & B) Private vacation home 476270 ## About the area ![Map](https://maps.googleapis.com/maps/api/staticmap?&size=660x330&map_id=3b266eb50d2997c6&zoom=13&markers=icon:https%3A%2F%2Fa.travel-assets.com%2Ftravel-assets-manager%2Feg-maps%2Fproperty.png%7C32.78935%2C-79.94918&channel=expedia-HotelInformation&maptype=roadmap&scale=1&key=AIzaSyCYjQus5kCufOpSj932jFoR_AJiL9yiwOw&signature=cEmQg9TXWXp-6vBuiHzzTBDmquE=) Charleston, SC #### What's nearby - Medical University of South Carolina - 5 min walk - 0.4 km - College of Charleston - 12 min walk - 1.0 km - Port of Charleston - 3 min drive - 2.6 km - Charleston City Market - 3 min drive - 3.0 km - South Carolina Aquarium - 3 min drive - 2.6 km #### Getting around - Charleston Station - 11 min drive - Charleston Intl. Airport (CHS) - 15 min drive #### Restaurants - ‪da Toscana Porchetta Shop - ‬4 min walk - ‪Daps Breakfast & Imbibe - ‬5 min walk - ‪The Co-Op - ‬6 min walk - ‪FUEL Charleston - ‬4 min walk - ‪Bad Bunnies Coffee - ‬2 min walk ## Frequently asked questions ### Is Guesthouse Charleston: SOUTH (105 A & B) pet-friendly? > No, pets are not allowed at this property. ### What time is check-in at Guesthouse Charleston: SOUTH (105 A & B)? > Check-in begins at 4:00 PM. ### What time is check-out at Guesthouse Charleston: SOUTH (105 A & B)? > Check-out is at 10:00 AM. ### Where is Guesthouse Charleston: SOUTH (105 A & B) located? > Located in Downtown Charleston, this vacation home is within 1 mi (2 km) of Medical University of South Carolina and College of Charleston. Port of Charleston is 1.6 mi (2.6 km) away. ## Have a question? Beta Get instant answers with AI powered search of property information and reviews. 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