Title: Book the Best Central West End SPA Resorts from CA $256 - Spa Hotels in Central West End, St. Louis | Expedia.ca [Central West End Travel Guide](https://expedia.ca/St-Louis-Central-West-End.dx6175135)[Vacation Rentals in St. Louis](https://expedia.ca/St-Louis-Vacation-Rentals.d178309.Travel-Guide-VacationRentals)[Flights to St. Louis](https://expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Central West End Car Rentals](https://expedia.ca/Car-Rentals-In-Central-West-End.d6175135.Car-Rental-Guide)[Central West End Vacations](https://expedia.ca/Central-West-End.d6175135.Destination-Travel-Guides) ![Central West End](https://images.trvl-media.com/place/6175135/69dc69e3-2092-4ca9-a34e-3187d2801679.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Central West End, St. Louis from CA $256 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central West End Spa Hotels Tonight [Nov 30 - Dec 1](https://www.expedia.ca/Hotel-Search?regionId=6175135&startDate=2025-11-30&endDate=2025-12-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 1 - Dec 2](https://www.expedia.ca/Hotel-Search?regionId=6175135&startDate=2025-12-01&endDate=2025-12-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6175135&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6175135&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central West End Spa Hotels ![Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/f78a36b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/502ee41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/d825c5c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/422bb82f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ameristar Casino Resort and Spa St. Charles 8.4/10 Very good (1009) "Beautiful hotel, spacious guestroom, comfortable beds, kind and helpful staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather [](https://www.expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/1c63195a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/fb7f173e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bedc886c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21C Museum Hotel St Louis Downtown West 9.0/10 Wonderful (1475) "Great staff and clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $213 CA $256 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Couples treatment rooms, hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/56a41562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/641d7f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel St Louis Downtown St. Louis 9.4/10 Exceptional (1006) "The staff was amazing. The bed was so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $580 CA $678 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/b7162ce8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/9a597e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/w4000h2663x0y0-dfd3faff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, St. Louis Clayton 9.2/10 Wonderful (553) "Service is exceptional!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge CA $697 CA $814 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-15&endDate=2025-12-16®ionId=6175135&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Central West End Hotel Reviews ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 10/10 Excellent "Very friendly staff. " [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) ![ The Royal Sonesta Chase Park Plaza St. Louis](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7_y.jpg) ### The Royal Sonesta Chase Park Plaza St. Louis 10/10 Excellent "Need to get better quality of wine" [](https://expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688_y.jpg) ### Drury Plaza Hotel St. Louis at the Arch 10/10 Excellent "The locTion was very well kept up and fantastic for my family. The pool was exactly what we needed at the end of the days. Great service and wondeful hospitality" [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Everyone on the staff was friendly and helpful. Breakfast each morning had a nice variety of items and the quality of the offerings was very nice. Parking was extremely cost effective. The location of this property was accessible to high quality shopping and dining options." [](https://expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg) ### Hyatt Regency St. Louis at The Arch 10/10 Excellent "Taylor, at the front desk, was amazing and so helpful. She answered my questions with ease during check-in, and continued to help throughout my stay. Taylor deserves a huge Thank you!" [](https://expedia.ca/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Central West End? > Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend the restaurants in Central West End. Take in the culture at the cathedral and museums during your stay. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your vacation. ### What's there to see and do in Central West End? > Enjoy all that Central West End has to offer and visit World Chess Hall of Fame, St. Louis Union Station, and Gateway Arch. If you have extra time while you're in the area, you might want to stop by St. Louis Science Center and The Muny Theater. ### What is a Central West End spa hotel? > Spa hotels in Central West End provide lodging and have a full on-site spa offering services such as therapies as well as beauty treatments. Some also offer in-room treatments. 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[Hotels near World Chess Hall of Fame](https://www.expedia.ca/World-Chess-Hall-Of-Fame-Hotels.0-l553248621555612614-0.Travel-Guide-Filter-Hotels) - [Flights to St. Louis](https://www.expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights) - [Flights to St Louis City County](https://www.expedia.ca/Destinations-In-St-Louis-City-County.d553248635976432800.Flight-Destinations) - [Missouri Botanical Gardens and Arboretum](https://www.expedia.ca/Missouri-Botanical-Gardens-And-Arboretum-St-Louis.d507258.Vacation-Attraction) - [Missouri History Museum](https://www.expedia.ca/Missouri-History-Museum-St-Louis.d6069383.Vacation-Attraction) - [Visit Academy - Sherman Park](https://www.expedia.ca/St-Louis-Academy-Sherman-Park.dx553248635976472137) - [St. Louis Art Museum](https://www.expedia.ca/St-Louis-Art-Museum-St-Louis.d502859.Vacation-Attraction) - [Visit Botanical Heights](https://www.expedia.ca/St-Louis-Botanical-Heights.dx896161994661642240) - [Visit Clayton-Tamm](https://www.expedia.ca/St-Louis-Clayton-Tamm.dx553248635976473263) - [Visit Compton Heights](https://www.expedia.ca/St-Louis-Compton-Heights.dx6351954) - [St. Louis Science Center](https://www.expedia.ca/St-Louis-Science-Center-Kings-Oak.d502861.Vacation-Attraction) - [St. Louis Union Station Mini Golf](https://www.expedia.ca/St-Louis-Union-Station-Mini-Golf-Downtown-West.d621092167072251904.Vacation-Attraction) - [St. Louis Zoo](https://www.expedia.ca/St-Louis-Zoo-St-Louis.d502878.Vacation-Attraction) - [St. Louis Vacations](https://www.expedia.ca/St-Louis.d178309.Destination-Travel-Guides) - [Visit St. Louis](https://www.expedia.ca/St-Louis.dx178309) - [Car rentals near St. Louis](https://www.expedia.ca/Car-Rentals-In-St-Louis.d178309.Car-Rental-Guide) - [St. Louis Vacation Rentals](https://www.expedia.ca/St-Louis-Vacation-Rentals.d178309.Travel-Guide-VacationRentals) - [Things to do in St. Louis](https://www.expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) - [Book Hotels in Central West End on Expedia.com](https://www.expedia.com/Central-West-End-St-Louis-Hotels-Spa-Hotel.0-n6175135-0-tSpaHotel.Travel-Guide-Filter-Hotels)