Title: Book the Best Central San Diego LUXURY Hotels - Upscale Hotels in Central San Diego, CA | Expedia.ca

[Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides)

![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find luxury hotels in Central San Diego, CA

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## Check availability on Central San Diego Luxury Hotels

Tonight

[Jan 5 - Jan 6](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-05&endDate=2026-01-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Jan 6 - Jan 7](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-06&endDate=2026-01-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Central San Diego luxury hotels

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2557x3y3-6971afdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3840h2556x0y3-1f0ee309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2557x3y3-2f0f89f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Seven Seas

[](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

Mission Valley

8.0/10

Very good

(3104)

"Breakfast was good and the staff was friendly and excellent. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thuan

CA $117

CA $134 total

includes taxes & fees

Jan 7 - Jan 8

[](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a73644b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/f52073d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kings Inn San Diego

[](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information)

Mission Valley

8.8/10

Excellent

(3600)

"Nice staff, clean rooms and the Waffle Spot!!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

brent

CA $102

CA $117 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information)

![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3456147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room, 2 Queen Beds, Accessible, Non Smoking (Mobility/Hearing Impaired)](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/30557300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/eff77449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham San Diego Hotel Circle

[](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information)

Mission Valley

8.0/10

Very good

(2446)

"Good budget hotel."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

MD

CA $116

CA $133 total

includes taxes & fees

Jan 22 - Jan 23

[](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/4be20fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/7c177216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/6f47bdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/bda1d22b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pleasant Inn

[](https://www.expedia.ca/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information)

Clairemont

8.4/10

Very good

(1294)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gene

CA $128

CA $147 total

includes taxes & fees

Jan 11 - Jan 12

[](https://www.expedia.ca/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/0a66ad12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/f15931a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/b197cd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/8399b5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency La Jolla

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information)

University City

8.8/10

Excellent

(1010)

"Really clean room, comfortable towels, would definitely come back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

CA $201

CA $282 total

includes taxes & fees

Jan 10 - Jan 11

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information)

![Hot springs](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d27fd38e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family dining](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/8eb9b186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Golf](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d2b2734e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Atwood Hotel San Diego - SeaWorld/Zoo

[](https://www.expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information)

Mission Valley

8.0/10

Very good

(1852)

"Great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michelle

[](https://www.expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/ed3f3759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/4093c285.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/0ce1ae8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/31240634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham San Diego Hotel Circle

[](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information)

Mission Valley

7.2/10

Good

(641)

"Staff was great, the room was very clean."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Jennifer

CA $99

CA $114 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/eb7ba8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/6ec53509.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/def5a1aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/c47d4d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Old Town Western Inn & Suites

[](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information)

Old Town San Diego

7.6/10

Good

(1009)

"Clean, good staff, quiet, good location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Raul

[](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/e1f8ca63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/567b3048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/ec648405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/15f7656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 San Diego, CA - Hotel Circle - Mission Valley

[](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information)

Mission Valley

6.8/10

(1482)

"The staff was pleasant and very accommodating."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

CA $112

CA $129 total

includes taxes & fees

Jan 16 - Jan 17

[](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/804dc72b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/d2021e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![42-inch TV with cable channels](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/c8cac925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/584e67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ramada Hotel & Conference Center by Wyndham San Diego North

[](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information)

Kearny Mesa

8.0/10

Very good

(942)

"Very friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21&regionId=6056570&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Central San Diego Hotel Reviews

![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg)

### San Diego Marriott La Jolla

10/10 Excellent

"Best hotel staff and stay "

[](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information)

![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg)

### Sheraton Mission Valley San Diego Hotel

10/10 Excellent

"Very nice room, clean and well taken care of. Outstanding staff with high customer service attitude. Nice drink and sundry shop. Convenient location to get anywhere to San Diego sites. Very nice pool area and restaurant. Only downside is room was noisy from the highway traffic, which of course is constant. Good white noise. My room also had a nice big deck."

[](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information)

![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg)

### California Suites Hotel

10/10 Excellent

"The staff, Breanna and Josh were super nice and helpful. My room was comfortable. I didn't get a chance to see the rest of the property. "

[](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information)

![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg)

### Hilton San Diego Mission Valley

10/10 Excellent

"Very courteous lady at the front counter. Great beds. "

[](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information)

![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg)

### Best Western Seven Seas

10/10 Excellent

"Room was good and staff was very friendly and helpful."

[](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg)

### DoubleTree by Hilton Hotel San Diego - Mission Valley

10/10 Excellent

"Good "

[](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information)

![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg)

### Hampton Inn San Diego/Mission Valley

10/10 Excellent

"Work place, meetin place, seimming pool, convenience shop, delicious and high quality breakfasts, Keeping all places very neat and clean. "

[](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information)

![Four Points by Sheraton San Diego](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d_y.jpg)

### Four Points by Sheraton San Diego

10/10 Excellent

"Yes"

[](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information)

![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg)

### Kings Inn San Diego

10/10 Excellent

"Great experience "

[](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information)

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