Title: Book the Best Central San Diego LUXURY Hotels - Upscale Hotels in Central San Diego, CA | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Central San Diego, CA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central San Diego Luxury Hotels Tonight [Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-23&endDate=2025-12-24&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-24&endDate=2025-12-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Central San Diego luxury hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2557x3y3-6971afdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/a6c5898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2557x3y3-2f0f89f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seven Seas [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) Mission Valley 8.0/10 Very good (3058) "Nice room, good ambiance, central location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANDREW CA $114 CA $131 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a73644b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/f52073d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kings Inn San Diego [](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) Mission Valley 8.8/10 Excellent (3569) "Clean and the amenities were outstanding, the staff was polite and helpful đź‘Ť " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) walter CA $102 CA $117 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/eff77449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3456147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego Hotel Circle [](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) Mission Valley 8.0/10 Very good (2432) "Clean room and excellent service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaime CA $116 CA $133 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/4be20fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/6f47bdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/bda1d22b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/7c177216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pleasant Inn [](https://www.expedia.ca/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information) Clairemont 8.4/10 Very good (1281) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene CA $129 CA $148 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/0a66ad12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/f15931a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/724f034d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/b197cd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency La Jolla [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information) University City 8.8/10 Excellent (1005) "Check in was great, employees were so nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Noel CA $197 CA $277 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information) ![Hot springs](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d2b2734e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/87f93e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family dining](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/8eb9b186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atwood Hotel San Diego - SeaWorld/Zoo [](https://www.expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) Mission Valley 8.0/10 Very good (1834) "Clean and helpful staff, thank you !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bora CA $97 CA $111 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/ed3f3759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/66a1c9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/0ce1ae8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/31240634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham San Diego Hotel Circle [](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information) Mission Valley 7.2/10 Good (626) "Hospility perfect and the breakfast towel the sheets and everything else super clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) reddi CA $99 CA $114 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/eb7ba8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/6ec53509.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/96ca9e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/def5a1aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Town Western Inn & Suites [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) Old Town San Diego 7.6/10 Good (1007) "Friendly staff and clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lola CA $139 CA $157 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/e1f8ca63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/567b3048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/ec648405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/0cdeeab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Diego, CA - Hotel Circle - Mission Valley [](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information) Mission Valley 6.8/10 (1480) "The staff was pleasant and very accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samuel CA $100 CA $116 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/804dc72b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/d2021e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/f581bd3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/584e67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Hotel & Conference Center by Wyndham San Diego North [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information) Kearny Mesa 8.0/10 Very good (942) "Very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-06&endDate=2026-01-07®ionId=6056570&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Central San Diego Hotel Reviews ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Great staff" [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Enjoyed my stay. The staff was friendly and helpful, the room was clean, comfortable and quiet. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Four Points by Sheraton San Diego](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d_y.jpg) ### Four Points by Sheraton San Diego 10/10 Excellent "Breakfast was good and an amazing deal when added during the initial reservation Plenty of easy parking Very clean The fitness center was pretty good too Bar had free popcorn Paying for parking on the reservation was also a good deal because you get 2 welcome drinks " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Had a really great experience at this hotel. Midge, the manager was super kind and accommodating. Great customer service from everyone, would definitely recommend to others coming to San Diego!!" [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Room spotless staff very pleasant. Breakfast good vaule " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Room was clean. It’s clearly an older facility that was beeen renovated. Loved the Christmas theme and energy. Breakfast not included, which is stated. There is a restaurant, the Waffle Spot or Stop, that was good with reasonable prices. " [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Room and staff were excellent" [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "Happy hour was a great perk" [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](https://images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "All are good I don’t use the restaurant or pool " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ## Explore a world of travel with Expedia - 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