Title: Book the Best Central San Diego LUXURY Hotels - Upscale Hotels in Central San Diego, CA | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![Balboa Park featuring aircraft and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21283-Balboa-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Central San Diego, CA ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central San Diego Luxury Hotels Tonight [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-09&endDate=2025-10-10&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-10&endDate=2025-10-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central San Diego Luxury Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/a6c5898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3840h2556x0y3-1f0ee309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2557x3y3-6971afdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seven Seas Mission Valley 7.8/10 Good (2965) "Great stay!" CA $118 CA $136 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a73644b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/f52073d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kings Inn San Diego Mission Valley 8.8/10 Excellent (3450) "Great place to stay!" CA $113 CA $130 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/eff77449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 2 Queen Beds, Accessible, Non Smoking (Mobility/Hearing Impaired)](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/30557300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3456147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego Hotel Circle Mission Valley 8.0/10 Very good (2359) "We loved our stay, great price, very clean and excellent location! " CA $123 CA $142 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/4be20fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/6f47bdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/ed8e473b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/7c177216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pleasant Inn Clairemont 8.4/10 Very good (1184) "Great place to stay for the price. Would definitely stay again when in town." CA $107 CA $123 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/0a66ad12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/b197cd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/724f034d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/8399b5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency La Jolla University City 8.8/10 Excellent (1006) "We had a great stay! Hotel staff and service were good. " CA $250 CA $339 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information) ![Hot springs](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d2b2734e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d27fd38e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family dining](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/8eb9b186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atwood Hotel San Diego - SeaWorld/Zoo Mission Valley 7.8/10 Good (1817) "Great customer service and decent rooms for the pricepoint." [](https://www.expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/ed3f3759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/31240634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/66a1c9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/0ce1ae8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham San Diego Hotel Circle Mission Valley 7.2/10 Good (515) "Business friendly, great staff good location" CA $109 CA $125 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/eb7ba8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/def5a1aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/c47d4d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/96ca9e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Town Western Inn & Suites Old Town San Diego 7.4/10 Good (1009) "A great place to stay" CA $133 CA $150 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/e1f8ca63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/ec648405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/0cdeeab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/567b3048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Diego, CA - Hotel Circle - Mission Valley Mission Valley 6.8/10 (1459) "Close to places I want to visit. " CA $106 CA $121 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/804dc72b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/bc796e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/584e67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/e2b8ef1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Hotel & Conference Center by Wyndham San Diego North Kearny Mesa 8.0/10 Very good (942) [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24®ionId=6056570&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Central San Diego Hotel Reviews ![Best Western Inn & Suites San Diego – Zoo/SeaWorld Area ](//images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771_y.jpg) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area 10/10 Excellent "El hotel está muy bien ubicado, cerca de todo. La habitación es cómoda, espaciosa y cuenta con un kitchenette muy funcional, ideal para una estadía práctica y agradable. El desayuno es sencillo pero decente, perfecto para comenzar el día. The hotel is very well located, close to everything. The room is comfortable, spacious, and includes a very functional kitchenette, perfect for a practical and pleasant stay. Breakfast is simple but decent, just right to start the day. " [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![Best Western Seven Seas](//images.trvl-media.com/lodging/1000000/10000/1800/1734/b8c3fa0d_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Parking was included, makes life much easier " [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Country Inn & Suites by Radisson, San Diego North, CA](//images.trvl-media.com/lodging/1000000/20000/16600/16546/abd318f6_y.jpg) ### Country Inn & Suites by Radisson, San Diego North, CA 10/10 Excellent "Very happy with our stay. The staff were friendly and helpful. The resteraunt was very good and our room was nice and quite, " [](https://expedia.ca/San-Diego-Hotels-Country-Inn-Suites-By-Radisson.h16546.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "One of the most affordable hotels in this area and its location makes it easy to get around San Diego." [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Nice place. Parking is pricey but, felt it was worth it to have vehicle in gated area. Very centrally located but still quiet." [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Enjoyed our stay. Staff was friendly and room was perfect. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Nice hotel" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![California Suites Hotel](//images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "Pleasant for our quick 1 night stay Clean Room Lots of storage space Bed is not v comfy but cant complain for 1 night Garden area is kept well Plenty parking but the condition of the road could be better " [](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ![Courtyard by Marriott San Diego Mission Valley/Hotel Circle](//images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/43ae1d02_y.jpg) ### Courtyard by Marriott San Diego Mission Valley/Hotel Circle 10/10 Excellent "Clean room nice staff" [](https://expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Mission-ValleyHotel-Circle.h1987617.Hotel-Information) ## Explore a world of travel with Expedia - 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