Title: Book the Best Central Missouri LUXURY Hotels - Upscale Hotels in Central Missouri, MO | Expedia.ca [Central Missouri Travel Guide](https://expedia.ca/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.ca/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Vacation Rentals in Central Missouri](https://expedia.ca/Central-Missouri-Vacation-Rentals.d6058776.Travel-Guide-VacationRentals)[Flights to Central Missouri](https://expedia.ca/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.ca/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Missouri.d6058776.Car-Rental-Guide)[Central Missouri Vacation Packages](https://expedia.ca/Central-Missouri.d6058776.Destination-Travel-Guides) ![Columbia featuring wild flowers](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257714-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Central Missouri, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Luxury Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Luxury Hotels ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/e7ee761d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/8a965f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/7ea5455a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Columbia Columbia 7.4/10 Good (1017) "A very nice, quiet, restful stay" CA $89 CA $101 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/4cb82576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/ae9109fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d2b3af17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d57fed98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### voco, The Tiger Hotel, Columbia, MO by IHG Columbia 8.8/10 Excellent (1000) "Excellent location with wonderful staff!" CA $201 CA $242 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/40992baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.4/10 Good (1037) "Friendly staff nice room restaurant was extremely good " CA $111 CA $147 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/e77a4ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1008) "Super convenient to the boat rental and fuel dock. " CA $138 CA $201 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/1e51ead0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/4b6bed2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/5f6cb0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/c6261cf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel Sedalia Downtown Historic District 9.2/10 Wonderful (561) "Historic hotel that was a great stop for our trip on the Katy Trail." CA $154 CA $176 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/350205ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/abe0b627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Smoking](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/70ee9896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/c053648f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Laci's Country Inn Knob Noster 7.0/10 Good (159) "Nice stay. " CA $86 CA $101 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bd7f5440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/c428cb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/fd258818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn Columbia 8.8/10 Excellent (1187) "Great place to stay! " CA $101 CA $114 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/52bc64ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/a99e46d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/184a1306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/3db07fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Columbia Clark Lane Columbia 6.6/10 (1002) "Good location. prefer a place with a hot breakfast." CA $76 CA $86 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/312544dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/cd10e4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/fc5d9ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/c159a6d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Boonville Boonville 6.4/10 (639) "Great stay" CA $82 CA $93 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/c69d8b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/57b8a773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/703e268d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks Osage Beach 7.2/10 Good (1006) "Location was within walking distance of decent restaurants and easy access to the highway." CA $100 CA $108 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=6058776&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ![Best Western Plus Columbia Inn](//images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Clean, staff was friendly " [](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Capitol Plaza Hotel Jefferson City](//images.trvl-media.com/lodging/1000000/10000/400/369/ad47cfa0_y.jpg) ### Capitol Plaza Hotel Jefferson City 10/10 Excellent "Hotel was amazing front desk staff couldn't have been better. Great weekend staff" [](https://expedia.ca/Columbia-Hotels-Capitol-Plaza-Hotel-Jefferson-City.h369.Hotel-Information) ![Baymont by Wyndham Columbia, MO](//images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Very clean and safe" [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Days Inn by Wyndham Rolla](//images.trvl-media.com/lodging/1000000/50000/40300/40279/1759c9c5_y.jpg) ### Days Inn by Wyndham Rolla 10/10 Excellent "I like construction, ie improvement but area is a little hard to sort out coming into parking lot. Tough for newbe’s. " [](https://expedia.ca/Rolla-Hotels-Days-Inn-By-Wyndham-Rolla.h40279.Hotel-Information) ![Stoney Creek Hotel Columbia](//images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "N/A" [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](//images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Very good hotel " [](https://expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Days Inn by Wyndham Osage Beach Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f_y.jpg) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks 10/10 Excellent "No issues" [](https://expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "My girlfriend and I visited on an impromptu getaway and it was amazing. The bed was very comfortable and the lake view every morning from my bed was amazing. The staff was welcoming and made sure we were cared for. Thanks Mike-who during check-in was so informative and Shawn at License to Chill- ran the place alone with excellence!" [](https://expedia.ca/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Quality Inn & Suites Columbia I-70](//images.trvl-media.com/lodging/1000000/20000/14600/14520/41147965_y.jpg) ### Quality Inn & Suites Columbia I-70 10/10 Excellent "Bed was very comfortable. Room was clean. The lady who prepared breakfast was very kind and accommodating. 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