Title: Book the Best Central Missouri LUXURY Hotels - Upscale Hotels in Central Missouri, MO | Expedia.ca [Central Missouri Travel Guide](https://expedia.ca/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.ca/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Vacation Rentals in Central Missouri](https://expedia.ca/Central-Missouri-Vacation-Rentals.d6058776.Travel-Guide-VacationRentals)[Flights to Central Missouri](https://expedia.ca/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.ca/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Missouri.d6058776.Car-Rental-Guide)[Central Missouri Vacation Packages](https://expedia.ca/Central-Missouri.d6058776.Destination-Travel-Guides) ![Missouri State Capitol which includes an administrative building, heritage architecture and a fountain](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Luxury Hotels Tonight [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2026-01-23&endDate=2026-01-24&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2026-01-24&endDate=2026-01-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Central Missouri luxury hotels ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/2c2e5fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/7ea5455a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/6a34339a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/87337ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Columbia [](https://www.expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) Columbia 7.6/10 Good (1,000 reviews) "Decent room for the price point " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $81 CA $92 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/17a25a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/5f1d172a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d2b3af17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/470645a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### voco The Tiger Hotel Columbia, MO by IHG [](https://www.expedia.ca/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) Columbia 9.0/10 Wonderful (1,002 reviews) "Staff was extremely friendly and helpful. Room was spotless and comfortable. We ate at Glenns Cafe and it was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pam CA $190 CA $237 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/a2724c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa [](https://www.expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) Lake Ozark 7.4/10 Good (1,102 reviews) "This is a wonderful hotel to stay. They have wonderful views and great space to relax. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee CA $179 CA $227 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/ecd45695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/3ff758b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/14793c30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/61a3503e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa [](https://www.expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) Lake Ozark 9.0/10 Wonderful (1,001 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel [](https://www.expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/22e30a85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/16c08a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/f26bf08a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/8ad6955b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel [](https://www.expedia.ca/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) Sedalia Downtown Historic District 9.2/10 Wonderful (585 reviews) "Great place. Beautifully decorated for the season. Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leah CA $144 CA $164 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/f96db8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/579bc607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/350205ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Smoking](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/70ee9896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Laci's Country Inn [](https://www.expedia.ca/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) Knob Noster 7.0/10 Good (162 reviews) "Room was super clean, spacious, and comfy bed. Great staff, fast wifi. Restaurant across the street. Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet Sison CA $78 CA $92 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/89f564da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bc9612c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/a18974cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) Columbia 9.0/10 Wonderful (1,225 reviews) "Very clean, smelled fresh, staff friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darci CA $95 CA $108 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/52bc64ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/a99e46d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/184a1306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Accessible bathroom](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/4fe8649e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Columbia Clark Lane [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) Columbia 6.6/10 (1,002 reviews) "Good hotel for the money." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie CA $73 CA $83 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) ![Studio Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/01e1d362.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/c159a6d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/w3000h1872x0y128-643a5db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/312544dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Boonville [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) Boonville 6.4/10 (653 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley CA $89 CA $100 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/d87275eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/b0575db1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/c69d8b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks [](https://www.expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Osage Beach 7.2/10 Good (1,001 reviews) "Clean, friendly staff. Comfortable room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug CA $80 CA $86 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-07&endDate=2026-02-08®ionId=6058776&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ![Stoney Creek Hotel Columbia](https://images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Cute hotel but could use some serious updates. The young guy at the front counter was not overly friendly and welcoming. Theres hardly any staff around. However, the rooms are nice and cozy. The beds are soft and comfy. The lounge chairs are nice also. Some of the staff were friendly and helpful. The breakfast bar is awesome. Overall, great stay and would go back again. " [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Capitol Plaza Hotel Jefferson City](https://images.trvl-media.com/lodging/1000000/10000/400/369/ad47cfa0_y.jpg) ### Capitol Plaza Hotel Jefferson City 10/10 Excellent "Older but very clean and quiet. Walking distance to a lot of bars and food places and places to shop. " [](https://expedia.ca/Columbia-Hotels-Capitol-Plaza-Hotel-Jefferson-City.h369.Hotel-Information) ![Hampton Inn & Suites Columbia at University](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009513/2702d693_y.jpg) ### Hampton Inn & Suites Columbia at University 10/10 Excellent "Easy check in and check out. Excellent breakfast. Clean rooms. " [](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Suites-Columbia-At-University.h2009513.Hotel-Information) ![Best Western Plus Columbia Inn](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "The staff are excellent and rooms clean. Always feel very comfortable and safe at this location." [](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Days Inn by Wyndham Rolla](https://images.trvl-media.com/lodging/1000000/50000/40300/40279/1759c9c5_y.jpg) ### Days Inn by Wyndham Rolla 10/10 Excellent "Room was clean and bed was comfortable. Temp control was also good. Room just looked a little worn" [](https://expedia.ca/Rolla-Hotels-Days-Inn-By-Wyndham-Rolla.h40279.Hotel-Information) ![Baymont by Wyndham Columbia, MO](https://images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Clean room. Good healthy breakfast options. Safe parking. Friendly staff." [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Really fun property with lots of trails. Really great staff. Love the sunken living room / conversation pit. 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