Title: Book the Best Central Missouri CASINO Hotels & Resorts in 2025 | Expedia.ca [Central Missouri Travel Guide](https://expedia.ca/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.ca/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Vacation Rentals in Central Missouri](https://expedia.ca/Central-Missouri-Vacation-Rentals.d6058776.Travel-Guide-VacationRentals)[Flights to Central Missouri](https://expedia.ca/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.ca/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Missouri.d6058776.Car-Rental-Guide)[Central Missouri Vacation Packages](https://expedia.ca/Central-Missouri.d6058776.Destination-Travel-Guides) ![Columbia featuring wild flowers](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257714-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Casino Hotels in Central Missouri, MO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Casino Hotels Tonight [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-11-01&endDate=2025-11-02&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-11-02&endDate=2025-11-03&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Casino Hotels ![Casino](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/d7688c2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/ebf5de16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/0c19f127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/43717afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination Boonville 8.2/10 Very good (908) "Great employees and clean, updated room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert [](https://www.expedia.ca/Columbia-Hotels-Isle-Of-Capri-Casino-Hotel-Boonville.h9747129.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/79000000/78770000/78767600/78767599/0a7dd6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78770000/78767600/78767599/22d88290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Blue Bird Room](https://images.trvl-media.com/lodging/79000000/78770000/78767600/78767599/be6bfa10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Le Cottage Le Mouton](https://images.trvl-media.com/lodging/79000000/78770000/78767600/78767599/9450ad7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boonville Luxury Lodging Boonville 10/10 Exceptional (36) "Linda and Ken are the best. Kind and gracious. The rooms are unique and lovely. The breakfasts are wonderful. Fresh fruit, egg and veggie fritata. Gourmet. Don't make the mistake of staying the night and leaving before breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael [](https://www.expedia.ca/Boonville-Hotels-High-Street-Bed-And-Breakfast.h78767599.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/75000000/74440000/74436800/74436704/w1242h919x0y5-873ec03f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/75000000/74440000/74436800/74436704/eb276e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74440000/74436800/74436704/b0b2fe41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74440000/74436800/74436704/250334ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Riverfront Cottage on Missouri River Jamestown 9.0/10 Wonderful (13) "The village of Lupus is unique, and the scenery is gorgeous. Cottage is clean, cozy and well appointed. A bit too far for back-and-forth to Mizzou, but perfect for a restful weekend away. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JACK CA $196 CA $263 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Jamestown-Hotels-Quiet-Riverfront-Cottage-On-Missouri-River.h74436704.Hotel-Information) ![2 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107120000/107111000/107110951/4ed5df15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107120000/107111000/107110951/734eec2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107120000/107111000/107110951/0281deb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107120000/107111000/107110951/43ed18b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Cozy Apartment 1 Bedroom In Peaceful Boonville Boonville 9.2/10 Wonderful (13) "This was my second time staying at this VRBO, and it was as great as the first time!! Having a comfortable place to land made our time in Boonville with old school buddies even more enjoyable. And our host was as responsive and accommodating as the first time I stayed! You can’t go wrong staying at this adorable rental!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trish W. CA $133 CA $296 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/Boonville-Hotels-Historic-Cozy-1-Bedroom-Apartment-With-Free-WiFi.h107110951.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/70000/60700/60685/e2cd2f48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/70000/60700/60685/e7278b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/60700/60685/e12ba737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/60700/60685/10dca268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn at Grand Glaize Laguna Beach 7.4/10 Good (248) "It was a nice stay. Very friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $93 CA $110 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Osage-Beach-Hotels-Inn-At-Grand-Glaize.h60685.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/89000000/88840000/88834800/88834739/ac01cda5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88840000/88834800/88834739/b03e5d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/89000000/88840000/88834800/88834739/133561bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/89000000/88840000/88834800/88834739/775b6d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Lakefront Home: Dock, Slips, SUPs, Kayaks Camdenton 10/10 Exceptional (9) "Enjoyed our time at the property, it worked perfectly for our family. Home is in new condition and has room to spread out. Many amenities we didn’t use." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey W. CA $231 CA $700 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Camdenton-Hotels-Luxury-Lakefront-Home-Dock.h88834739.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/43000000/42340000/42333100/42333041/3d508028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42340000/42333100/42333041/4bb808f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/43000000/42340000/42333100/42333041/abcbf401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/43000000/42340000/42333100/42333041/9ec49140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxurious Historic Home at the heart of Columbia Columbia 10/10 Exceptional (34) "House was beautiful and spotless. Hosts were incredible. We had a wonderful time. Perfect for friend groups visiting students at Mizzou!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darci M. CA $1,191 CA $1,584 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Columbia-Hotels-Luxurious-Historic-Home-At-The-Heart-Of-Columbia.h42333041.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/20000000/19430000/19428500/19428477/e7df1c8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/20000000/19430000/19428500/19428477/70fccb87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/20000000/19430000/19428500/19428477/ca057c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, books](https://images.trvl-media.com/lodging/20000000/19430000/19428500/19428477/56aed515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stunning Updated 5 Bedroom/5 bath Margaritaville Resort Lake Front View Home! Osage Beach 9.0/10 Wonderful (133) "The property is amazing with plentiful parking and lodging. The beds were comfortable and the rooms were very open. There was not much we needed from the owner but when we did need something, the owner was quick to respond and very helpful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry P. CA $603 CA $1,243 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Osage-Beach-Hotels-Stunning-Updated-5-Bedroom5-Bath-Margaritaville-Resort-Lake-Front-View-Home.h19428477.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24200/24177/eff785b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24200/24177/9055520d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24200/24177/9bf178e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24200/24177/4dbaea2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Select Kansas City South Overland Park South Kansas City 8.2/10 Very good (1005) "Good place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene CA $110 CA $133 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Kansas-City-Hotels-Sonesta-Select-Kansas-City-South-Overland-Park.h24177.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/115000000/114920000/114915600/114915532/7874a8a1_edited_29ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/115000000/114920000/114915600/114915532/31619adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/115000000/114920000/114915600/114915532/5f2e21f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/115000000/114920000/114915600/114915532/86c5c83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Lion Inn & Suites Blue Springs Blue Springs 6.8/10 (143) "Staff was friendly and helpful. Would stay again in the future " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $84 CA $98 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Kansas-City-Hotels-Red-Lion-Inn-Suites-Blue-Springs.h114915532.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=6058776&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Apache Flats Hotels](https://www.expedia.ca/Apache-Flats-Hotels.d553248635975850469.Travel-Guide-Hotels) - [Farmstay in California](https://www.expedia.ca/California-Agritourism.d6351831-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in California](https://www.expedia.ca/California-Apart-Hotels.d6351831-aaApartHotels.Travel-Guide-Accommodation) - [B&B in California](https://www.expedia.ca/California-Bed-And-Breakfast.d6351831-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in California](https://www.expedia.ca/California-Guest-Houses.d6351831-aaGuestHouses.Travel-Guide-Accommodation) - [Cheap Hotels in California](https://www.expedia.ca/California-Hotels-Cheap-Hotels.0-0-d6351831-tCheapHotels.Travel-Guide-Filter-Hotels) - 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