Title: Book the Best BUSINESS Hotels in Central Iowa in 2026 | Expedia.ca [Central Iowa Travel Guide](https://expedia.ca/Central-Iowa.dx6059968)[Hotels in Central Iowa](https://expedia.ca/Central-Iowa-Hotels.d6059968.Travel-Guide-Hotels)[Vacation Rentals in Central Iowa](https://expedia.ca/Central-Iowa-Vacation-Rentals.d6059968.Travel-Guide-VacationRentals)[Flights to Central Iowa](https://expedia.ca/Cheap-Flights-To-Central-Iowa.d6059968.Travel-Guide-Flights)[Things to do in Central Iowa](https://expedia.ca/Things-To-Do-In-Central-Iowa.d6059968.Travel-Guide-Activities)[Central Iowa Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Iowa.d6059968.Car-Rental-Guide)[Central Iowa Vacation Packages](https://expedia.ca/Central-Iowa.d6059968.Destination-Travel-Guides) ![John and Mary Pappajohn Sculpture Park featuring outdoor art and a park](https://images.trvl-media.com/place/6287745/f794efaf-aa4c-4107-9bcc-c5b49c2ee926.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Central Iowa, IA from CA $92 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Iowa Business Hotels Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6059968&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6059968&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6059968&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6059968&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Central Iowa business-friendly hotels ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7790000/7783000/7782906/710b9a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7790000/7783000/7782906/20dbc359.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/8000000/7790000/7783000/7782906/4406592c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/8000000/7790000/7783000/7782906/86eb1e22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites - Newton [](https://www.expedia.ca/Marshalltown-Hotels-Cobblestone-Inn-Suites-Newton.h7782906.Hotel-Information) Newton 9.2/10 Wonderful (811) "Hotel worked out great for what we needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslee CA $128 CA $144 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Marshalltown-Hotels-Cobblestone-Inn-Suites-Newton.h7782906.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952095/53b23e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952095/b1fc3405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking (1 Kingbed)](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952095/46745b84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952095/33997a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Fairfield [](https://www.expedia.ca/Ottumwa-Hotels-AmericInn-By-Wyndham-Fairfield.h4952095.Hotel-Information) Fairfield 9.2/10 Wonderful (558) "Breakfast area looked inviting room was clean overal was a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $135 CA $151 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Ottumwa-Hotels-AmericInn-By-Wyndham-Fairfield.h4952095.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/9e1ed185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/c5a53e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/823be9f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/840c2132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites By Wyndham Clear Lake [](https://www.expedia.ca/Mason-City-Hotels-Microtel-Inn-Suites-By-Wyndham-Clear-Lake.h523133.Hotel-Information) Clear Lake 8.4/10 Very good (1000) "Great breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $82 CA $92 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Mason-City-Hotels-Microtel-Inn-Suites-By-Wyndham-Clear-Lake.h523133.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/24000000/23640000/23639000/23638966/a9cf9cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/24000000/23640000/23639000/23638966/4c0e4443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/24000000/23640000/23639000/23638966/36c9e17e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23640000/23639000/23638966/808d9444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Marshalltown by IHG [](https://www.expedia.ca/Marshalltown-Hotels-Holiday-Inn-Express-Suites-Marshalltown.h23638966.Hotel-Information) Marshalltown 9.4/10 Exceptional (327) "Great breakfast, nice clean and safe place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $143 CA $160 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Marshalltown-Hotels-Holiday-Inn-Express-Suites-Marshalltown.h23638966.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15030000/15022400/15022303/e07c1310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Refrigerator & Microwave (Wet Bar)](https://images.trvl-media.com/lodging/16000000/15030000/15022400/15022303/eb26c10b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15030000/15022400/15022303/752bc43b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15030000/15022400/15022303/241d42aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Altoona-Des Moines [](https://www.expedia.ca/Des-Moines-Hotels-Hampton-Inn-Suites-Altoona-Des-Moines.h15022303.Hotel-Information) Altoona 9.2/10 Wonderful (670) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald J CA $124 CA $139 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Des-Moines-Hotels-Hampton-Inn-Suites-Altoona-Des-Moines.h15022303.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/f073330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/7678811d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/f92883cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/3e508ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Diamond Jo Worth Casino Hotel [](https://www.expedia.ca/Northwood-Hotels-Country-Inn-Suites-By-Radisson.h1580597.Hotel-Information) Northwood 8.6/10 Excellent (620) "love that it is connected to casino, very clean, reasonable pricing, great free breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ERIC CA $142 CA $159 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Northwood-Hotels-Country-Inn-Suites-By-Radisson.h1580597.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382319/bc7b776d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382319/b3f3f0cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382319/f985ff42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382319/7442fc46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Ottumwa [](https://www.expedia.ca/Ottumwa-Hotels-Hotel-Ottumwa.h6382319.Hotel-Information) Ottumwa 8.2/10 Very good (514) "Great old historic hotel! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela CA $84 CA $95 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Ottumwa-Hotels-Hotel-Ottumwa.h6382319.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1668000/1667983/f02d4dc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1670000/1668000/1667983/bf859e87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, Select Comfort beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1670000/1668000/1667983/6e6b788e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1670000/1668000/1667983/338b6258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Grinnell near I-80 [](https://www.expedia.ca/Marshalltown-Hotels-Comfort-Inn-And-Suites.h1667983.Hotel-Information) Grinnell 8.4/10 Very good (472) "Very friendly staff, nice clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $104 CA $117 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Marshalltown-Hotels-Comfort-Inn-And-Suites.h1667983.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/4b3ca419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/54d4a4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/0482e45b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/bd8e6aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Clear Lake [](https://www.expedia.ca/Mason-City-Hotels-AmericInn-By-Wyndham-Clear-Lake.h658042.Hotel-Information) Clear Lake 9.0/10 Wonderful (1001) "Friendly staff, nice breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $104 CA $117 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Mason-City-Hotels-AmericInn-By-Wyndham-Clear-Lake.h658042.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-27&endDate=2025-12-28®ionId=6059968&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Iowa Hotel Reviews ![Drury Inn & Suites West Des Moines](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/2af2a76d_y.jpg) ### Drury Inn & Suites West Des Moines 10/10 Excellent "Efficient and friendly at the front desk. Room was clean and comfortable. Breakfast was delicious!" [](https://expedia.ca/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Des Moines West Clive](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/0778119f_y.jpg) ### La Quinta Inn & Suites by Wyndham Des Moines West Clive 10/10 Excellent "Room was very clean and the staff was amazing. " [](https://expedia.ca/Des-Moines-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Des-Moines-West-Clive.h50111.Hotel-Information) ![Country Inn & Suites by Radisson, Des Moines West, IA](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/cede0cf8_y.jpg) ### Country Inn & Suites by Radisson, Des Moines West, IA 10/10 Excellent "clean room" [](https://expedia.ca/Des-Moines-Hotels-Country-Inn-Suites-By-Radisson.h99780.Hotel-Information) ![Des Lux Hotel](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "Wonderful, friendly staff. Stunning lobby! The room was large and immaculate." [](https://expedia.ca/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Ramada Tropics Resort & Conf Center by Wyndham Des Moines](https://images.trvl-media.com/lodging/1000000/10000/1600/1547/b8de3671_y.jpg) ### Ramada Tropics Resort & Conf Center by Wyndham Des Moines 6/10 Okay "Yes" [](https://expedia.ca/Des-Moines-Hotels-Ramada-Tropics-Resort-Conf-Center-By-Wyndham-Des-Moines.h1547.Hotel-Information) ![Days Inn & Suites by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/23994ff1_y.jpg) ### Days Inn & Suites by Wyndham Des Moines Airport 10/10 Excellent "Perfect " [](https://expedia.ca/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![AmericInn by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/860000/856000/855969/6f15108b_y.jpg) ### AmericInn by Wyndham Des Moines Airport 10/10 Excellent "The ability to shuttle to the airport and leave my car in a safe spot was great" [](https://expedia.ca/Des-Moines-Hotels-AmericInn-By-Wyndham-Des-Moines-Airport.h855969.Hotel-Information) ![Stoney Creek Hotel Des Moines - Johnston](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/8b967b66_y.jpg) ### Stoney Creek Hotel Des Moines - Johnston 10/10 Excellent "Room was clean but smoke alarm was hanging from the ceiling so check your rooms for maintenance. Staff was very friendly and helpful at desk. Housekeeping did knock and try to enter our room before I could answer the door at 10am, an hour before checkout, so educate them to let us answer. It takes 15 seconds, not 3\. A do not disturb sign would have helped. Otherwise it's a nice place." [](https://expedia.ca/Des-Moines-Hotels-Stoney-Creek-Hotel-Des-Moines-Johnston.h1152222.Hotel-Information) ![Hyatt Place Des Moines/Downtown](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/c5d9ac95_y.jpg) ### Hyatt Place Des Moines/Downtown 10/10 Excellent "Staff very friendly at check in and helpful with parking issue. " [](https://expedia.ca/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Central Iowa cost? ### What are the best business-friendly hotels in Central Iowa? ### How many business-friendly hotels are there in Central Iowa? ### What are the best cheap business-friendly hotels in Central Iowa? ### Are there any family-friendly hotels in Central Iowa that are also business friendly? ### Why book your business-friendly hotel in Central Iowa with Expedia? ### How can I find cheap business-friendly hotels in Central Iowa? ### What is there to do in Central Iowa near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [3 Star Hotels in Garden City ](https://www.expedia.ca/3Star-Garden-City-Hotels.s30-0-d865694245001158656.Travel-Guide-Filter-Hotels) - [B&B in Ames ](https://www.expedia.ca/Ames-Bed-And-Breakfast.d6059972-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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