Title: Book the Best BUSINESS Hotels in Central Chile in 2026 | Expedia.ca [Central Chile Travel Guide](https://expedia.ca/Central-Chile.dx6053652)[Hotels in Central Chile](https://expedia.ca/Central-Chile-Hotels.d6053652.Travel-Guide-Hotels)[Vacation Rentals in Central Chile](https://expedia.ca/Central-Chile-Vacation-Rentals.d6053652.Travel-Guide-VacationRentals)[Flights to Central Chile](https://expedia.ca/Cheap-Flights-To-Central-Chile.d6053652.Travel-Guide-Flights)[Things to do in Central Chile](https://expedia.ca/Things-To-Do-In-Central-Chile.d6053652.Travel-Guide-Activities)[Central Chile Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Chile.d6053652.Car-Rental-Guide)[Central Chile Vacation Packages](https://expedia.ca/Central-Chile.d6053652.Destination-Travel-Guides) ![Santa Lucia Hill featuring château or palace](https://images.trvl-media.com/place/6072103/b1883d18-f359-432b-b894-3dda3a149fb8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Central Chile from CA $124 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Chile Business Hotels Tonight [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=6053652&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6053652&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6053652&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6053652&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Central Chile business-friendly hotels ![Property amenity](https://images.trvl-media.com/lodging/2000000/1740000/1738600/1738554/869a6bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1740000/1738600/1738554/e5074959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1740000/1738600/1738554/dc5d4ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1740000/1738600/1738554/a083690d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santiago - Airport Terminal by IHG [](https://www.expedia.ca/Santiago-Hotels-Holiday-Inn-Santiago-Airport-Terminal.h1738554.Hotel-Information) Pudahuel 9.0/10 Wonderful (1414) "The hotel is inside the airport, good for one night stay on transit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Xinping CA $227 CA $254 total Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Santiago-Hotels-Holiday-Inn-Santiago-Airport-Terminal.h1738554.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21950000/21943300/21943233/1463398a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21950000/21943300/21943233/f7c4890c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21950000/21943300/21943233/d2eff9e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21950000/21943300/21943233/5d4753dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Santiago Aeropuerto [](https://www.expedia.ca/Santiago-Hotels-La-Quinta-By-Wyndham-Santiago-Aeropuerto.h21943233.Hotel-Information) Pudahuel 9.0/10 Wonderful (1150) "The staff was great and the hotel very clean. The complementary airport shuttle was amazing." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Romaric CA $144 CA $144 total Dec 28 - Dec 29 [](https://www.expedia.ca/Santiago-Hotels-La-Quinta-By-Wyndham-Santiago-Aeropuerto.h21943233.Hotel-Information) ![Panoramic Suite | Living area](https://images.trvl-media.com/lodging/1000000/20000/15200/15107/0c4d3cf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar, pool views, open daily](https://images.trvl-media.com/lodging/1000000/20000/15200/15107/b15b1748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Bedrooms](https://images.trvl-media.com/lodging/1000000/20000/15200/15107/67935906.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/15200/15107/46b703b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mandarin Oriental, Santiago [](https://www.expedia.ca/Santiago-Hotels-Mandarin-Oriental.h15107.Hotel-Information) Las Condes 9.2/10 Wonderful (939) "Great hotel, staff, food, location, EVERYTHING! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariano CA $371 CA $371 total Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/Santiago-Hotels-Mandarin-Oriental.h15107.Hotel-Information) ![Breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/11000000/10510000/10501700/10501672/874ec2ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Corner](https://images.trvl-media.com/lodging/11000000/10510000/10501700/10501672/8c402c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10510000/10501700/10501672/w3996h2667x0y0-b2d68b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10510000/10501700/10501672/5aecbd5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Santiago Airport [](https://www.expedia.ca/Santiago-Hotels-Hotel-Manquehue-Aeropuerto.h10501672.Hotel-Information) Pudahuel 8.6/10 Excellent (596) "Overall a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evangeline CA $163 CA $163 total Jan 25 - Jan 26, 2026 [](https://www.expedia.ca/Santiago-Hotels-Hotel-Manquehue-Aeropuerto.h10501672.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4280000/4272700/4272697/37ddf345.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/5000000/4280000/4272700/4272697/4272792a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4280000/4272700/4272697/852b9f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4280000/4272700/4272697/4cf37017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Santiago Airport [](https://www.expedia.ca/Santiago-Hotels-Hilton-Garden-Inn-Santiago-Airport.h4272697.Hotel-Information) Pudahuel 8.6/10 Excellent (1001) "Location, the room condition and airport shuttle service is excellent." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) paras CA $151 CA $151 total Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Santiago-Hotels-Hilton-Garden-Inn-Santiago-Airport.h4272697.Hotel-Information) ![In-room safe, desk, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/17000000/16010000/16006600/16006510/7e82fd20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/17000000/16010000/16006600/16006510/3dda6cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16010000/16006600/16006510/a861c699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/17000000/16010000/16006600/16006510/f97a2731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Santiago Aeropuerto Chile [](https://www.expedia.ca/Santiago-Hotels-City-Express-Santiago-Aeropuerto.h16006510.Hotel-Information) Pudahuel 8.8/10 Excellent (1002) "Thank you, nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eduard CA $124 CA $124 total Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Santiago-Hotels-City-Express-Santiago-Aeropuerto.h16006510.Hotel-Information) ![Superior Double Room, 2 Single Beds](https://images.trvl-media.com/lodging/17000000/16610000/16602400/16602399/1fab63ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/17000000/16610000/16602400/16602399/05bf88bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/17000000/16610000/16602400/16602399/ccac2885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/17000000/16610000/16602400/16602399/39606318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casino de Talca [](https://www.expedia.ca/Talca-Hotels-Hotel-Casino-De-Talca.h16602399.Hotel-Information) Talca 8.4/10 Very good (57) "It was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $129 CA $129 total Dec 28 - Dec 29 [](https://www.expedia.ca/Talca-Hotels-Hotel-Casino-De-Talca.h16602399.Hotel-Information) ![Beach/ocean view](https://images.trvl-media.com/lodging/14000000/13140000/13133200/13133188/63a62579.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Ocean View](https://images.trvl-media.com/lodging/14000000/13140000/13133200/13133188/43948a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/14000000/13140000/13133200/13133188/21a99c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/14000000/13140000/13133200/13133188/770aa9f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Oceanic [](https://www.expedia.ca/Vina-Del-Mar-Hotels-Hotel-Oceanic.h13133188.Hotel-Information) Vina del Mar 8.2/10 Very good (169) "The breakfast was wonderful and always came on time. The staff were friendly and helpful. The views and property were outstanding. We always enjoy our stay here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $167 CA $167 total Dec 28 - Dec 29 [](https://www.expedia.ca/Vina-Del-Mar-Hotels-Hotel-Oceanic.h13133188.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/b6c7442f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/4b01e3a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, body treatments, hydrotherapy, body wraps](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/2713a051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Cruz Plaza [](https://www.expedia.ca/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information) Santa Cruz 8.6/10 Excellent (335) "Yes all great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barrett CA $175 CA $175 total Dec 28 - Dec 29 [](https://www.expedia.ca/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/afe65d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/d646bdcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/3c454a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/e7b99456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Perla Hotel [](https://www.expedia.ca/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information) Santa Cruz 9.2/10 Wonderful (101) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $146 CA $146 total Dec 27 - Dec 28 [](https://www.expedia.ca/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=6053652&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Chile Hotel Reviews ![ICON Hotel](https://images.trvl-media.com/lodging/18000000/17720000/17714200/17714108/a84e03a0_y.jpg) ### ICON Hotel 10/10 Excellent "Werr" [](https://expedia.ca/Santiago-Hotels-ICON-Hotel.h17714108.Hotel-Information) ![DoubleTree by Hilton Hotel Santiago - Vitacura](https://images.trvl-media.com/lodging/9000000/8370000/8362400/8362336/ac27341a_y.jpg) ### DoubleTree by Hilton Hotel Santiago - Vitacura 10/10 Excellent "Nice room " [](https://expedia.ca/Santiago-Hotels-DoubleTree-By-Hilton-Hotel-Santiago-Vitacura.h8362336.Hotel-Information) ![Solace Hotel Santiago](https://images.trvl-media.com/lodging/13000000/12600000/12597200/12597149/e2c3ab0d_y.jpg) ### Solace Hotel Santiago 10/10 Excellent "Staff particularly helpful. Very much ch enjoyed stay." [](https://expedia.ca/Santiago-Hotels-Solace-Hotel-Santiago.h12597149.Hotel-Information) ![Almacruz Hotel y Centro de Convenciones](https://images.trvl-media.com/lodging/1000000/10000/1500/1496/b4c00de4_y.jpg) ### Almacruz Hotel y Centro de Convenciones 10/10 Excellent "The rooms were clean and the staff were very nice and helpful. The buffet breakfast was amazing and coffee was strong! Best of all, the location is central in downtown, walking distance to many landmarks. :)" [](https://expedia.ca/Santiago-Hotels-Almacruz-Hotel-Y-Centro-De-Convenciones.h1496.Hotel-Information) ![Holiday Inn Santiago - Airport Terminal by IHG](https://images.trvl-media.com/lodging/2000000/1740000/1738600/1738554/869a6bea_y.jpg) ### Holiday Inn Santiago - Airport Terminal by IHG 10/10 Excellent "The hotel is inside the airport, good for one night stay on transit" [](https://expedia.ca/Santiago-Hotels-Holiday-Inn-Santiago-Airport-Terminal.h1738554.Hotel-Information) ![City Express by Marriott Santiago Aeropuerto Chile](https://images.trvl-media.com/lodging/17000000/16010000/16006600/16006510/7e82fd20_y.jpg) ### City Express by Marriott Santiago Aeropuerto Chile 10/10 Excellent "Great service, very comfortable " [](https://expedia.ca/Santiago-Hotels-City-Express-Santiago-Aeropuerto.h16006510.Hotel-Information) ![Radisson Blu Plaza El Bosque Santiago](https://images.trvl-media.com/lodging/8000000/7440000/7439500/7439466/f9e32c0d_y.jpg) ### Radisson Blu Plaza El Bosque Santiago 10/10 Excellent "Clean room, comfortable bed, great breakfast, excellent customer service!!" [](https://expedia.ca/Santiago-Hotels-Hotel-Plaza-El-Bosque-Nueva-Las-Condes.h7439466.Hotel-Information) ![Mandarin Oriental, Santiago](https://images.trvl-media.com/lodging/1000000/20000/15200/15107/0c4d3cf8_y.jpg) ### Mandarin Oriental, Santiago 10/10 Excellent "The room is spacious with outstanding design, facing beautiful views. Bath designs and two-shower heads made users feel very comfortable. The breakfast through room service orders is excellent, we ordered pre-evenings, the service staff delivered exactly on times early morning. Food quality is super, with delicious taste and healthy options. Taxi arrangement is the best out of all my past experience. The price is even lower than Uber, driver came onsite waiting for us 10min before requested time, with a very good suv, and smooth driving to airport. All staff from reception desk, room service, restaurant, are very friendly and doing their job efficiently. " [](https://expedia.ca/Santiago-Hotels-Mandarin-Oriental.h15107.Hotel-Information) ![Hotel Casa Zañartu ](https://images.trvl-media.com/lodging/20000000/19130000/19128100/19128038/ec548c8d_y.jpg) ### Hotel Casa Zañartu 10/10 Excellent "Staff was great, helped with an extra late check in and check out (providing snacks at checkout since we wouldn't be able to have breakfast). Organizing a ride to and from the airport was also easy through them. Room was clean but a bit dark and squeeky floors. Good stay overall" [](https://expedia.ca/Santiago-Hotels-Casa-Zanartu.h19128038.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Central Chile cost? ### What are the best business-friendly hotels in Central Chile? ### How many business-friendly hotels are there in Central Chile? ### What are the best cheap business-friendly hotels in Central Chile? ### Are there any family-friendly hotels in Central Chile that are also business friendly? ### Are there any 5-star business-friendly hotels in Central Chile? ### Why book your business-friendly hotel in Central Chile with Expedia? ### How can I find cheap business-friendly hotels in Central Chile? ### What is there to do in Central Chile near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [Farmstay in Chile ](https://www.expedia.ca/Chile-Agritourism.d36-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Chile ](https://www.expedia.ca/Chile-Apart-Hotels.d36-aaApartHotels.Travel-Guide-Accommodation) - 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