Title: Book the Best Castro District SPA Resorts from CA $256 - Spa Hotels in Castro District, San Francisco | Expedia.ca [Castro District Travel Guide](https://expedia.ca/San-Francisco-Castro-District.dx179363)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Castro District Car Rentals](https://expedia.ca/Car-Rentals-In-Castro-District.d179363.Car-Rental-Guide)[Castro District Vacations](https://expedia.ca/Castro-District.d179363.Destination-Travel-Guides) ![Castro Theatre showing a small town or village and street scenes](https://images.trvl-media.com/place/6155068/ab312681-9b33-4d50-b3a8-85b62e6145db.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Castro District, San Francisco from CA $256 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Castro District Spa Hotels Tonight [Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=179363&startDate=2025-12-23&endDate=2025-12-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=179363&startDate=2025-12-24&endDate=2025-12-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=179363&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=179363&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Castro District Hotel Reviews ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Good" [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Very friendly staff. " [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Hotel Nikko San Francisco](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12_y.jpg) ### Hotel Nikko San Francisco 10/10 Excellent "Front desk staff was incredible " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "Staff is great and received an unexpected upgrade!" [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "Absolutely lovely " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "All good so far!" [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Hotel Zoe Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/21cb8d87_y.jpg) ### Hotel Zoe Fisherman's Wharf 10/10 Excellent "Great service and hotel location. Will definitely stay there again. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) ![Hilton San Francisco Airport Bayfront](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7b6b8635_y.jpg) ### Hilton San Francisco Airport Bayfront 10/10 Excellent "The Room was Excallent & Jerrick & Jr were so friendly " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information) ![Beacon Grand, A Union Square Hotel ](https://images.trvl-media.com/lodging/1000000/20000/15300/15254/6f8c6b2f_y.jpg) ### Beacon Grand, A Union Square Hotel 10/10 Excellent "Beautiful hotel. Great amenities. Love the updated decor and bathroom. Also we enjoyed the lobby restaurant and bar. All over wonderful experience - I highly recommend staying here" [](https://expedia.ca/San-Francisco-Hotels-Sir-Francis-Drake-Hotel.h15254.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Castro District? ### What's there to see and do in Castro District? ### What is a Castro District spa hotel? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Cheap Hotels in Cole Valley ](https://www.expedia.ca/Cole-Valley-San-Francisco-Hotels-Cheap-Hotels.0-n3000663429-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Cole Valley ](https://www.expedia.ca/Cole-Valley-San-Francisco-Hotels-Hotels-With-Bar.0-n3000663429-0-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Cole Valley ](https://www.expedia.ca/Cole-Valley-San-Francisco-Hotels-Luxury-Hotel.0-n3000663429-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Dolores Heights ](https://www.expedia.ca/Dolores-Heights-San-Francisco-Hotels-Luxury-Hotel.0-n553248635976470582-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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