Title: The 10 Best Hotels Near Cape Romain National Wildlife Refuge, from CA $124 | Expedia.ca [South Carolina Travel Guide](https://expedia.ca/South-Carolina.dx242)[Vacation Rentals in South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Vacation-Rental-Destinations)[Flights to South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations)[Things to do in South Carolina](https://expedia.ca/Things-To-Do-In-South-Carolina.d242.Travel-Guide-Activities)[Cape Romain National Wildlife Refuge Car Rentals](https://expedia.ca/Car-Rentals-In-Cape-Romain-National-Wildlife-Refuge.d553248621532654965.Car-Rental-Guide)[Cape Romain National Wildlife Refuge Vacations](https://expedia.ca/Cape-Romain-National-Wildlife-Refuge-South-Carolina.d553248621532654965.Vacation-Attraction) ![We had to take a ferry in the dark to get here at sunrise. They only do this at certain times during the year. I love chasing the sunrise. #adventure](https://images.trvl-media.com/place/3000422486/29abaa56-9255-457f-af06-9426eac9b0d2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by ‎‎Carla Be # Find hotels near Cape Romain National Wildlife Refuge, from CA $124 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Cape Romain National Wildlife Refuge hotels ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/201dd650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/90b6962f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/97ba3df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/f67441fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) 33.2 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1003) "Clean room, excellent facility, perfect location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim CA $284 CA $382 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/e3cb0887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/1d6befc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/c8a0b3b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/fbde3014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) 36.7 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1001) "Everything about my stay here has been a delight, clean room, professional & friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $120 CA $136 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/3fa5d3b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/a6d131e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/b037af83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/66e9726f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) 37.4 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1001) "Great place to stay!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fredrick CA $124 CA $144 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/7d430968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/cc1c7e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/69a1b766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/074573fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Mt Pleasant Charleston [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) 39.4 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1460) "It was a great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alashia CA $122 CA $141 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/0b1f10c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/026d91a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/9f988e82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Balcony (Oceanfront)](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/c627c06b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palms Oceanfront Hotel [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) 37.8 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1061) "Very clean and location was great!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clarisa CA $159 CA $184 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/ac1e1a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/a169ee52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/3c942196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/f18d338c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites at Isle Of Palms Connector [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) 37.4 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1001) "The staff was friendly and the room was exceptionally clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) RAYMOND CA $104 CA $124 total includes taxes & fees Jan 25 - Jan 26, 2026 [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/2a58c84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/1a811942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/035f9783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/82b75f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Mt Pleasant Charleston [](https://www.expedia.ca/Charleston-Hotels-Home2-Suites-By-Hilton-Mt-Pleasant-Charleston.h19950102.Hotel-Information) 38.2 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1002) "Variety of breakfast options - hotel and room felt clean overall - lots of dining options nearby " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah CA $133 CA $151 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Charleston-Hotels-Home2-Suites-By-Hilton-Mt-Pleasant-Charleston.h19950102.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/247bf02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/9c1a9374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/48d70dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/e59ead2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Mount Pleasant – Charleston [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) 39.8 km from Cape Romain National Wildlife Refuge 9.4/10 Exceptional (1826) "Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shu-Ting CA $127 CA $146 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) ![Luxury Cabin, Kitchen, Garden View | Private kitchen](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d1a7199e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | Living area](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d784ae68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | Living area](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d33bd814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/03e692d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wicklow Hall [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) 27.5 km from Cape Romain National Wildlife Refuge CA $458 CA $509 total includes taxes & fees Jan 27 - Jan 28, 2026 [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/f77e4dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/1c3c4bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/0f73b639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/aaa4616b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) 37.3 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (183) "Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Holly CA $161 CA $182 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) ![Coffee/tea maker](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/3874a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/b28f7eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/de429beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/90f9d74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Residences at Sweetgrass [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) 33.2 km from Cape Romain National Wildlife Refuge 8.6/10 Excellent (176) "Love it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lawanda CA $313 CA $420 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/4deeaf46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/a6beb27a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/a96ab8be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/d3883d13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Charleston / Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) 39.7 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1000) "Good value and great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Howard CA $159 CA $182 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/2f83f27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/c66aafe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/51b37dff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/3ffc745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Charleston - Mt Pleasant [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) 37.2 km from Cape Romain National Wildlife Refuge 8.4/10 Very good (1000) "Courteous staff and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Loushon CA $152 CA $175 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/6244861e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/58202b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/60638c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/1e85c521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) 40.6 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1000) "Front desk personnel were very nice and professional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Viviane CA $128 CA $147 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e4e88b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/c55f5199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e71ca0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/99f7ffe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) 39.5 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1000) "We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $138 CA $156 total includes taxes & fees Jan 22 - Jan 23, 2026 [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/078f2f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/e193d994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/22d3b448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/6e95483e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seaside Inn Oceanfront [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) 38 km from Cape Romain National Wildlife Refuge 7.6/10 Good (1002) "Great place to stay!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $187 CA $217 total includes taxes & fees Jan 14 - Jan 15, 2026 [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/cc1f0b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/0e7d9026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/w4000h2663x0y0-740f59de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/2301806f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites Charleston Mt. Pleasant [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) 40.6 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (523) "Great place to stay. Dog friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gabriela CA $150 CA $170 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11®ionId=553248621532654965&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Cape Romain National Wildlife Refuge Hotel Reviews ![Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/201dd650_y.jpg) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn 10/10 Excellent "Great resort, beautiful beach, ton of restaurant and food options. Close enough to Charleston for a day trip to town. Would highly recommend. " [](https://expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Beautiful home with open porches overlooking lagoon in Wild Dunes](https://images.trvl-media.com/lodging/71000000/70060000/70059300/70059230/38b8716b_y.jpg) ### Beautiful home with open porches overlooking lagoon in Wild Dunes 10/10 Excellent "Property was wonderful, just needed a few more towels " [](https://expedia.ca/Isle-Of-Palms-Hotels-Beautiful-Home-With-Open-Porches-Overlooking-Lagoon-In-Wild-Dunes.h70059230.Hotel-Information) ![Seascape 317 - View! Beach! Pool!](https://images.trvl-media.com/lodging/113000000/112760000/112754600/112754586/908ea7d9_y.jpg) ### Seascape 317 - View! Beach! Pool! 10/10 Excellent "Seascape 317 was an amazing place to stay! The oceanfront views were absolutely breathtaking — the kind you can enjoy from morning coffee to sunset. Inside, the faux fireplace added such a cozy ambiance, and the superb TV made it perfect for relaxing and watching the game.The Ninja coffee maker was a great touch, offering both regular brew and K-cup options, and the fully equipped kitchen had everything we needed. The hosts were extremely responsive as well, which made the entire experience even better.We loved our stay and would definitely return!" [](https://expedia.ca/Isle-Of-Palms-Hotels-New-Listing-Seascape-317-View-Beach-Pool.h112754586.Hotel-Information) ![Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean!](https://images.trvl-media.com/lodging/102000000/101470000/101460100/101460091/c5de9db1_y.jpg) ### Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean! 10/10 Excellent "The code didn't work when we first arrived, thankfully it was early enough to get someone at the office who provided an extra code. Several times when we asked for help Carrol Realty was very responsive (fixing light bulbs in closet and desk) and helping to arrange house cleaning. Great location. " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Condo-In-Wild-Dunes-Community-Pool-Great-View-Looking-At-Ocean.h101460091.Hotel-Information) ![Port O' Call E303 - Sensational Top Floor View!](https://images.trvl-media.com/lodging/28000000/27140000/27134400/27134370/f2be615d_y.jpg) ### Port O' Call E303 - Sensational Top Floor View! 10/10 Excellent "Wonderful views. Safe and quiet. Everything was labeled ( my wife loved that). All amenities right there and available at your fingertips. Even minute details were covered. Stress free. I did ask the hosts to adopt us but they respectfully declined . We'll be back!" [](https://expedia.ca/Charleston-Hotels-Port-O-Call-E303-Sensational-Oceanview-Top-Floor.h27134370.Hotel-Information) ![52 Ocean Point-New Oceanfront Home-New Listing-5 Bedrooms-Five Baths-Absolutely Stunning Views in...](https://images.trvl-media.com/lodging/113000000/112830000/112822300/112822270/6c20868b_y.jpg) ### 52 Ocean Point-New Oceanfront Home-New Listing-5 Bedrooms-Five Baths-Absolutely Stunning Views in... 10/10 Excellent "Everything about our stay was perfect. Great communication, great house and amazing view. We will look to rent here again. " [](https://expedia.ca/Isle-Of-Palms-Hotels-52-Ocean-Point-New-Oceanfront-Home-New-Listing-5-Bedrooms-Five-Baths-Absolutely-Stunning-Views-In.h112822270.Hotel-Information) ![Oceanfront Top Floor Villa, Large Balcony, & Community Pool in Wild Dunes!](https://images.trvl-media.com/lodging/91000000/90930000/90929800/90929799/4ca2bcbb_y.jpg) ### Oceanfront Top Floor Villa, Large Balcony, & Community Pool in Wild Dunes! 10/10 Excellent "Very clean and spacious place. We really enjoyed the stay . Thank you " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Top-Floor-Villa.h90929799.Hotel-Information) ![Oceanfront Condo with Community Pool, Beach Access, Ocean & Beach Views and Private Covered Balcony](https://images.trvl-media.com/lodging/60000000/59360000/59352200/59352168/171d457a_y.jpg) ### Oceanfront Condo with Community Pool, Beach Access, Ocean & Beach Views and Private Covered Balcony 10/10 Excellent "Had everything we needed" [](https://expedia.ca/Charleston-Hotels-Oceanfront-Condo-With-Community-Pool.h59352168.Hotel-Information) ![Mesmerizing Oceanfront Views! 3 Min. Walk to Quiet Beach & Community Pool w/ Cabana](https://images.trvl-media.com/lodging/67000000/66090000/66090000/66089948/936dccc2_y.jpg) ### Mesmerizing Oceanfront Views! 3 Min. Walk to Quiet Beach & Community Pool w/ Cabana 10/10 Excellent "Great house and location. Had a great family trip " [](https://expedia.ca/Charleston-Hotels-Mesmerizing-Oceanfront-Views-3-Min-Walk-To-Quiet-Beach-Community-Pool-W-Hot-Tub-Cabana.h66089948.Hotel-Information) ## Hotels near other Cape Romain National Wildlife Refuge attractions ![AC0TKJ The Harbor Golf Course Wild Dunes Island Resort Isle of Palms near Charleston South Carolina](https://images.trvl-media.com/place/553248621558078484/32d931cd-699d-43d6-9aa0-fa34b4c7f216.jpg) ### Wild Dunes Resort Golf Course 4.3/5 (29 reviews) Enjoy a round of golf in Isle of Palms at Wild Dunes Resort Golf Course. Stroll along the beautiful beaches in this family-friendly area, or check out its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078484) ![singer island florida sis fish marina palm beach shours florida sail fish marina and docks ](https://images.trvl-media.com/place/553248621558078488/715d6d03-e4d0-4a6a-ba59-71663655eb97.jpg) ### Isle of Palms Marina 4.4/5 (49 reviews) Explore the waterfront in Isle of Palms with a trip to Isle of Palms Marina. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078488) ![Beach Front, Isle of Palms, South Carolina](https://images.trvl-media.com/place/553248621558078487/ee804706-feb1-451b-a148-6b38196711c2.jpg) ### Front Beach 4.5/5 (27 reviews) If a restful vacation is part of your travel plans, Front Beach might be the perfect place to seek out during your trip to Isle of Palms. Stroll along the seaside or visit the shops while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078487) ### Dewees Island Beach 4.1/5 (14 reviews) Why not spend a lazy afternoon at Dewees Island Beach during your trip to Isle of Palms? Amble around this relaxing area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976496939) ### Charleston National Golf Club 5.0/5 (1 review) Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Check out the top-notch restaurants or lively bars in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082649) ### Goat Island Commune with nature and explore the great outdoors at Goat Island during your travels in Mount Pleasant. Amble around the area's riverfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635975748887) ### Charleston Fun Park You can take time to visit Charleston Fun Park during your travels to Mount Pleasant. Stroll along the waterfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=802133948876271616) ### Dunes West Golf and River Club 4.4/5 (83 reviews) Enjoy a round of golf in Mount Pleasant at Dunes West Golf and River Club. Check out the lively bars or top-notch restaurants in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082653) ## Frequently asked questions ### What's the area like around Cape Romain National Wildlife Refuge? ### What's the best hotel to stay close to Cape Romain National Wildlife Refuge? ### If I need to cancel the hotel reservation for my stay near Cape Romain National Wildlife Refuge, will I receive a refund? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Seaside Farms ](https://www.expedia.ca/5Star-Seaside-Farms-Mount-Pleasant-Hotels.s50-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [B&B in Awendaw ](https://www.expedia.ca/Awendaw-Bed-And-Breakfast.d3000422486-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Awendaw ](https://www.expedia.ca/Awendaw-Hotels-Cheap-Hotels.0-0-d3000422486-tCheapHotels.Travel-Guide-Filter-Hotels) - [Awendaw Hotels ](https://www.expedia.ca/Awendaw-Hotels.d3000422486.Travel-Guide-Hotels) - 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[Pet-Friendly Hotels in Seaside Farms ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Pet-Friendly-Hotel.0-n553248635976473485-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Seaside Farms ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Ski-Hotel.0-n553248635976473485-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Seaside Farms ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Spa-Hotel.0-n553248635976473485-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Seaside Farms Hotels ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels.0-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [Hotels near Shem Creek Park ](https://www.expedia.ca/Shem-Creek-Park-Hotels.0-l6335305-0.Travel-Guide-Filter-Hotels) - [Ski Hotels in Snee Farm ](https://www.expedia.ca/Snee-Farm-Mount-Pleasant-Hotels-Ski-Hotel.0-n553248635976470912-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Hotels near Sullivan's Island Beach ](https://www.expedia.ca/Sullivans-Island-Beach-Hotels.0-l553248635976496796-0.Travel-Guide-Filter-Hotels) - [Sullivan's Island Hotels ](https://www.expedia.ca/Sullivans-Island-Hotels.d6161251.Travel-Guide-Hotels) - [Hotels with Kitchenettes in The Commons ](https://www.expedia.ca/The-Commons-Isle-Of-Palms-Hotels-Hotels-With-Kitchenettes.0-n553248635976469553-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in The Commons ](https://www.expedia.ca/The-Commons-Isle-Of-Palms-Hotels-Pet-Friendly-Hotel.0-n553248635976469553-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in Twin Oaks ](https://www.expedia.ca/Twin-Oaks-Isle-Of-Palms-Hotels-Hotels-With-Free-Parking.0-n553248635976480655-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Twin Oaks Hotels ](https://www.expedia.ca/Twin-Oaks-Isle-Of-Palms-Hotels.0-n553248635976480655-0.Travel-Guide-Filter-Hotels) - [Wando Hotels ](https://www.expedia.ca/Wando-Hotels.d3000456159.Travel-Guide-Hotels) - [Vacation Homes in Wando ](https://www.expedia.ca/Wando-Private-Vacation-Homes.d3000456159-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Rv Parks in Wando ](https://www.expedia.ca/Wando-RV-Parks.d3000456159-aaRVParks.Travel-Guide-Accommodation) - [Hotels near Wild Dunes Resort Golf Course ](https://www.expedia.ca/Wild-Dunes-Resort-Golf-Course-Hotels.0-l553248621558078484-0.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Yacht Harbor Court ](https://www.expedia.ca/Yacht-Harbor-Court-Isle-Of-Palms-Hotels-Adults-Only-Resorts.0-n553248635976468614-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Business Hotels in Yacht Harbor Court ](https://www.expedia.ca/Yacht-Harbor-Court-Isle-Of-Palms-Hotels-Business-Hotel.0-n553248635976468614-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Yacht Harbor Court Hotels ](https://www.expedia.ca/Yacht-Harbor-Court-Isle-Of-Palms-Hotels.0-n553248635976468614-0.Travel-Guide-Filter-Hotels) - [Flights to Isle of Palms ](https://www.expedia.ca/Cheap-Flights-To-Isle-Of-Palms.d118827.Travel-Guide-Flights) - [Flights from Awendaw ](https://www.expedia.ca/lp/flights/3000422486/flights-from-awendaw) - [Blackbeard's Cove Family Fun Park ](https://www.expedia.ca/Blackbeards-Cove-Family-Fun-Park-Mount-Pleasant.d6335266.Vacation-Attraction) - [Charleston National Golf Club ](https://www.expedia.ca/Charleston-National-Golf-Club-Charleston-National.d6082649.Vacation-Attraction) - [Front Beach ](https://www.expedia.ca/Front-Beach-Isle-of-Palms.d553248621558078487.Vacation-Attraction) - [Isle of Palms Vacations ](https://www.expedia.ca/Isle-Of-Palms.d118827.Destination-Travel-Guides) - [Visit Isle of Palms ](https://www.expedia.ca/Isle-Of-Palms.dx118827) - [Wild Dunes Resort Golf Course ](https://www.expedia.ca/Wild-Dunes-Resort-Golf-Course-Isle-of-Palms.d553248621558078484.Vacation-Attraction) - [Car rental Isle of Palms ](https://www.expedia.ca/Car-Rentals-In-Isle-Of-Palms.d118827.Car-Rental-Guide) - [Car rental Wando ](https://www.expedia.ca/Car-Rentals-In-Wando.d3000456159.Car-Rental-Guide) - [Isle of Palms Vacation Rentals ](https://www.expedia.ca/Isle-Of-Palms-Vacation-Rentals.d118827.Travel-Guide-VacationRentals) - [Things to do in Isle of Palms ](https://www.expedia.ca/Things-To-Do-In-Isle-Of-Palms.d118827.Travel-Guide-Activities)