Title: The 10 Best Hotels Near Cape Romain National Wildlife Refuge, from CA $125 | Expedia.ca [South Carolina Travel Guide](https://expedia.ca/South-Carolina.dx242)[Vacation Rentals in South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Vacation-Rental-Destinations)[Flights to South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations)[Things to do in South Carolina](https://expedia.ca/Things-To-Do-In-South-Carolina.d242.Travel-Guide-Activities)[Cape Romain National Wildlife Refuge Car Rentals](https://expedia.ca/Car-Rentals-In-Cape-Romain-National-Wildlife-Refuge.d553248621532654965.Car-Rental-Guide)[Cape Romain National Wildlife Refuge Vacations](https://expedia.ca/Cape-Romain-National-Wildlife-Refuge-South-Carolina.d553248621532654965.Vacation-Attraction) ![Watching the sunrise on Bull island is must do, no cars allowed. Go enjoy the peace and quiet. #adventurephotocontest #adventure](https://images.trvl-media.com/place/3000422486/94209f72-ca2d-4afa-90d8-ba5bdfb2a18a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by ‎‎Carla Be # Find hotels near Cape Romain National Wildlife Refuge, from CA $125 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 5 - Jan 6](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-05&endDate=2026-01-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 6 - Jan 7](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-06&endDate=2026-01-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Cape Romain National Wildlife Refuge hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/247bf02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/48d70dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/e59ead2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/9c1a9374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Mount Pleasant – Charleston [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) 39.8 km from Cape Romain National Wildlife Refuge 9.4/10 Exceptional (1852) "Excellent stay in Charleston! Great staff great location and VERY clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $127 CA $147 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/7d430968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/69a1b766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/cc1c7e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/0efb7a1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Mt Pleasant Charleston [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) 39.4 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1478) "Staff was great, good breakfast options, comfortable bed and close to attractions!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristle CA $133 CA $153 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/e3cb0887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/1d6befc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/581d948f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/fbde3014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) 36.7 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1004) "Check in was great…clean and well appointed rooms. Breakfast was excellent as well…all the basics plus a few extras. Dining room area was spacious and well laid out with lots of places for singles and family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marvin CA $128 CA $144 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/4deeaf46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/d3883d13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/b00d98a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/a6beb27a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Charleston / Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) 39.7 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1002) "Good value and great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Howard CA $153 CA $176 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/3fa5d3b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/b037af83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/66e9726f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/a6d131e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) 37.4 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1004) "Staff was very nice and the stay was very pleasant. Daily breakfast was on point as well. Would definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen CA $128 CA $148 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/201dd650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/f67441fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/13d4a8ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/97ba3df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) 33.2 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1006) "We loved this resort! It was comfortable, convenient, and had a touch of everything for everyone. A great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Meghan CA $286 CA $384 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/6244861e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/1e85c521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/60638c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/58202b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) 40.6 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1017) "Hotel staff was very friendly and room was very spacious and clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leeat CA $128 CA $148 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/66c38012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/cfce3ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/d681e891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/fe7118dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Mount Pleasant Towne Centre [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Mount-Pleasant-Towne-Centre.h32131907.Hotel-Information) 37.9 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1003) "Staff was friendly Room very spacious and clean. Beds were very comfortable. Great location to all the shops. Close to lots of restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynn CA $164 CA $202 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Mount-Pleasant-Towne-Centre.h32131907.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/cc1f0b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/0e7d9026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/w4000h2663x0y0-740f59de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds | Private kitchen](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/9bcf1669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites Charleston Mt. Pleasant [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) 40.6 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (524) "Great place to stay. Dog friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gabriela CA $151 CA $171 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/f77e4dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/1c3c4bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/aaa4616b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/2b0df1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) 37.3 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (186) "Great service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather CA $162 CA $183 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e4e88b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e71ca0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/99f7ffe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/c3cdc692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) 39.5 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1002) "We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $139 CA $157 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/2f83f27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/c66aafe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/4d52f615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/3ffc745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Charleston - Mt Pleasant [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) 37.2 km from Cape Romain National Wildlife Refuge 8.4/10 Very good (1006) "Courteous staff and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Loushon CA $153 CA $175 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/0b1f10c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/37423c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/9f988e82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/026d91a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palms Oceanfront Hotel [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) 37.8 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1067) "Great staff, cute restaurants close by" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica M CA $159 CA $185 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/ac1e1a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/3c942196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/d9739fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/f18d338c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites at Isle Of Palms Connector [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) 37.4 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1011) "Was very comfortable and clean and well laid out!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Heather CA $105 CA $125 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/078f2f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/af6cdcf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/e193d994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/6e95483e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seaside Inn Oceanfront [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) 38 km from Cape Romain National Wildlife Refuge 7.6/10 Good (1003) "Great location, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rhonda Lee [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) ![Coffee/tea maker](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/3874a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/90f9d74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/4f6106a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/de429beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Residences at Sweetgrass [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) 33.2 km from Cape Romain National Wildlife Refuge 8.6/10 Excellent (178) "Love it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lawanda CA $307 CA $413 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) ![Luxury Cabin, Kitchen, Garden View | Private kitchen](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d1a7199e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | Living area](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d33bd814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/03e692d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | Living area](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d784ae68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wicklow Hall [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) 27.5 km from Cape Romain National Wildlife Refuge CA $454 CA $504 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21®ionId=553248621532654965&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Cape Romain National Wildlife Refuge Hotel Reviews ![Beautiful home with open porches overlooking lagoon in Wild Dunes](https://images.trvl-media.com/lodging/71000000/70060000/70059300/70059230/38b8716b_y.jpg) ### Beautiful home with open porches overlooking lagoon in Wild Dunes 10/10 Excellent "Property was wonderful, just needed a few more towels " [](https://expedia.ca/Isle-Of-Palms-Hotels-Beautiful-Home-With-Open-Porches-Overlooking-Lagoon-In-Wild-Dunes.h70059230.Hotel-Information) ![Seascape 317 - View! Beach! Pool!](https://images.trvl-media.com/lodging/113000000/112760000/112754600/112754586/908ea7d9_y.jpg) ### Seascape 317 - View! Beach! Pool! 10/10 Excellent "Seascape 317 was an amazing place to stay! The oceanfront views were absolutely breathtaking — the kind you can enjoy from morning coffee to sunset. Inside, the faux fireplace added such a cozy ambiance, and the superb TV made it perfect for relaxing and watching the game.The Ninja coffee maker was a great touch, offering both regular brew and K-cup options, and the fully equipped kitchen had everything we needed. The hosts were extremely responsive as well, which made the entire experience even better.We loved our stay and would definitely return!" [](https://expedia.ca/Isle-Of-Palms-Hotels-New-Listing-Seascape-317-View-Beach-Pool.h112754586.Hotel-Information) ![Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean!](https://images.trvl-media.com/lodging/102000000/101470000/101460100/101460091/c5de9db1_y.jpg) ### Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean! 10/10 Excellent "The code didn't work when we first arrived, thankfully it was early enough to get someone at the office who provided an extra code. Several times when we asked for help Carrol Realty was very responsive (fixing light bulbs in closet and desk) and helping to arrange house cleaning. Great location. " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Condo-In-Wild-Dunes-Community-Pool-Great-View-Looking-At-Ocean.h101460091.Hotel-Information) ![Port O' Call E303 - Sensational Top Floor View!](https://images.trvl-media.com/lodging/28000000/27140000/27134400/27134370/f2be615d_y.jpg) ### Port O' Call E303 - Sensational Top Floor View! 10/10 Excellent "Wonderful views. Safe and quiet. Everything was labeled ( my wife loved that). All amenities right there and available at your fingertips. Even minute details were covered. Stress free. I did ask the hosts to adopt us but they respectfully declined . We'll be back!" [](https://expedia.ca/Charleston-Hotels-Port-O-Call-E303-Sensational-Oceanview-Top-Floor.h27134370.Hotel-Information) ![Mid Century Modern meets Beach Chic - Practically Oceanfront with pool access](https://images.trvl-media.com/lodging/65000000/64920000/64917500/64917428/3c85e3af_y.jpg) ### Mid Century Modern meets Beach Chic - Practically Oceanfront with pool access 10/10 Excellent "The view from the porch was wonderful! The condo was very comfortable and decorated so tastefully. The spiral staircase which led upstairs and to the lookout deck was an excellent addition. The stairs would be a challenge for several of my friends. I had everything I needed…coffee…view…great pillows…tv…wine glasses and comfortable bed! The location couldn’t be beat. I hope to stay here again. Beth communicated with me clearly and quickly. " [](https://expedia.ca/Isle-Of-Palms-Hotels-Mid-Century-Modern-Meets-Beach-Chic-Practically-Oceanfront-With-Pool-Access.h64917428.Hotel-Information) ![High Tide By AvantStay | Incredible Beach Front Home w/ Pool](https://images.trvl-media.com/lodging/62000000/61640000/61639800/61639729/b7b36fb0_y.jpg) ### High Tide By AvantStay | Incredible Beach Front Home w/ Pool 10/10 Excellent "The view!!!! Most times you may look at photos on vrbo and think to yourself, is this real life?? This indeed is real life at High Tide! The view of the 18th hole and a hop over the dunes to the ocean is majestic. The house was fully stocked with everything you need for a marvelous stay. We even grilled our first night because we couldn’t pull ourselves away from the view. Met the owners who were sweet as pie and Avantstay were so communicative and there if we needed anything. Even suggested the best places to eat. It was a great get away and we have talked about returning for sure. If you want a beautiful house with an amazing view, comfy beds, full kitchen, and all the comforts of home, this is the house for you!!! " [](https://expedia.ca/Isle-Of-Palms-Hotels-High-Tide-By-AvantStay-Incredible-Beach-Front-Home-W-Pool.h61639729.Hotel-Information) ![Updated Home in Exclusive Gated Ocean Point Wild Dunes 4 min walk to Beach &Pool](https://images.trvl-media.com/lodging/29000000/28770000/28767100/28767013/w637h477x3y3-0923fd80_y.jpg) ### Updated Home in Exclusive Gated Ocean Point Wild Dunes 4 min walk to Beach &Pool 10/10 Excellent "Beautiful house with anything you could need! We had a wonderful time and the host was great with communication." [](https://expedia.ca/Isle-Of-Palms-Hotels-Updated-Home-In-Exclusive-Gated-Ocean-Point-Wild-Dunes-3-Min-Walk-To-Beach-Pool.h28767013.Hotel-Information) ![Oceanfront! Wild Dunes. Port O’ Call.](https://images.trvl-media.com/lodging/35000000/34170000/34168400/34168397/9295e338_y.jpg) ### Oceanfront! Wild Dunes. Port O’ Call. 10/10 Excellent "This was our second stay at this property. Love the convenience to the beach but is in a quiet area. Condo is clean and the beach chairs are a great addition." [](https://expedia.ca/Charleston-Hotels-Newly-Renovated-First-Floor-Walk-Out-Beautiful-Ocean-Views.h34168397.Hotel-Information) ![Oceanfront Top Floor Villa, Large Balcony, & Community Pool in Wild Dunes!](https://images.trvl-media.com/lodging/91000000/90930000/90929800/90929799/4ca2bcbb_y.jpg) ### Oceanfront Top Floor Villa, Large Balcony, & Community Pool in Wild Dunes! 10/10 Excellent "Very clean and spacious place. We really enjoyed the stay . Thank you " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Top-Floor-Villa.h90929799.Hotel-Information) ## Hotels near other Cape Romain National Wildlife Refuge attractions ![AC0TKJ The Harbor Golf Course Wild Dunes Island Resort Isle of Palms near Charleston South Carolina](https://images.trvl-media.com/place/553248621558078484/32d931cd-699d-43d6-9aa0-fa34b4c7f216.jpg) ### Wild Dunes Resort Golf Course 4.3/5 (29 reviews) Enjoy a round of golf in Isle of Palms at Wild Dunes Resort Golf Course. Stroll along the seaside in this romantic area, or check out its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078484) ![singer island florida sis fish marina palm beach shours florida sail fish marina and docks ](https://images.trvl-media.com/place/553248621558078488/715d6d03-e4d0-4a6a-ba59-71663655eb97.jpg) ### Isle of Palms Marina 4.4/5 (49 reviews) Explore the waterfront in Isle of Palms with a trip to Isle of Palms Marina. Check out the shops and top-notch restaurants in this romantic area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078488) ![Beach Front, Isle of Palms, South Carolina](https://images.trvl-media.com/place/553248621558078487/ee804706-feb1-451b-a148-6b38196711c2.jpg) ### Front Beach 4.5/5 (27 reviews) If a restful vacation is part of your travel plans, Front Beach might be the perfect place to seek out during your trip to Isle of Palms. Stroll along the seaside or visit the shops while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078487) ### Dewees Island Beach 4.1/5 (14 reviews) Why not spend a lazy afternoon at Dewees Island Beach during your trip to Isle of Palms? Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976496939) ### Charleston National Golf Club 5.0/5 (1 review) Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Check out the top-notch restaurants or lively bars in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082649) ### Goat Island Commune with nature and explore the great outdoors at Goat Island during your travels in Mount Pleasant. Amble around the area's riverfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635975748887) ### Charleston Fun Park You can take time to visit Charleston Fun Park during your travels to Mount Pleasant. Stroll along the waterfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=802133948876271616) ### Dunes West Golf and River Club 4.4/5 (83 reviews) Enjoy a round of golf in Mount Pleasant at Dunes West Golf and River Club. Check out the lively bars or top-notch restaurants in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082653) ## Frequently asked questions ### What's the area like around Cape Romain National Wildlife Refuge? ### What's the best hotel to stay close to Cape Romain National Wildlife Refuge? ### If I need to cancel the hotel reservation for my stay near Cape Romain National Wildlife Refuge, will I receive a refund? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Seaside Farms ](https://www.expedia.ca/5Star-Seaside-Farms-Mount-Pleasant-Hotels.s50-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [B&B in Awendaw ](https://www.expedia.ca/Awendaw-Bed-And-Breakfast.d3000422486-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Awendaw ](https://www.expedia.ca/Awendaw-Hotels-Cheap-Hotels.0-0-d3000422486-tCheapHotels.Travel-Guide-Filter-Hotels) - [Awendaw Hotels ](https://www.expedia.ca/Awendaw-Hotels.d3000422486.Travel-Guide-Hotels) - 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[Blackbeard's Cove Family Fun Park ](https://www.expedia.ca/Blackbeards-Cove-Family-Fun-Park-Mount-Pleasant.d6335266.Vacation-Attraction) - [Charleston National Golf Club ](https://www.expedia.ca/Charleston-National-Golf-Club-Charleston-National.d6082649.Vacation-Attraction) - [Front Beach ](https://www.expedia.ca/Front-Beach-Isle-of-Palms.d553248621558078487.Vacation-Attraction) - [Isle of Palms Vacations ](https://www.expedia.ca/Isle-Of-Palms.d118827.Destination-Travel-Guides) - [Visit Isle of Palms ](https://www.expedia.ca/Isle-Of-Palms.dx118827) - [Wild Dunes Resort Golf Course ](https://www.expedia.ca/Wild-Dunes-Resort-Golf-Course-Isle-of-Palms.d553248621558078484.Vacation-Attraction) - [Car rental Isle of Palms ](https://www.expedia.ca/Car-Rentals-In-Isle-Of-Palms.d118827.Car-Rental-Guide) - [Car rental Wando ](https://www.expedia.ca/Car-Rentals-In-Wando.d3000456159.Car-Rental-Guide) - [Isle of Palms Vacation Rentals ](https://www.expedia.ca/Isle-Of-Palms-Vacation-Rentals.d118827.Travel-Guide-VacationRentals) - 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