Title: The 10 Best Hotels Near Cape Romain National Wildlife Refuge, from CA $122 | Expedia.ca [South Carolina Travel Guide](https://expedia.ca/South-Carolina.dx242)[Vacation Rentals in South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Vacation-Rental-Destinations)[Flights to South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations)[Things to do in South Carolina](https://expedia.ca/Things-To-Do-In-South-Carolina.d242.Travel-Guide-Activities)[Cape Romain National Wildlife Refuge Car Rentals](https://expedia.ca/Car-Rentals-In-Cape-Romain-National-Wildlife-Refuge.d553248621532654965.Car-Rental-Guide)[Cape Romain National Wildlife Refuge Vacations](https://expedia.ca/Cape-Romain-National-Wildlife-Refuge-South-Carolina.d553248621532654965.Vacation-Attraction) ![Watching the sunrise on Bull island is must do, no cars allowed. Go enjoy the peace and quiet. #adventurephotocontest #adventure](https://images.trvl-media.com/place/3000422486/94209f72-ca2d-4afa-90d8-ba5bdfb2a18a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by ‎‎Carla Be ![](https://images.trvl-media.com/place/3000422486/94209f72-ca2d-4afa-90d8-ba5bdfb2a18a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 25 - Jan 26](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-25&endDate=2026-01-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Cape Romain National Wildlife Refuge hotels ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/201dd650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/90b6962f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/8611736c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/97ba3df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) 33.2 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1,003 reviews) "We loved this resort! It was comfortable, convenient, and had a touch of everything for everyone. A great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Meghan CA $285 CA $383 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/87b27d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/b2c4a3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/581d948f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/937f5ff3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) 36.7 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1,000 reviews) "Hotel was clean and comfortable. Staff was very friendly, polite and accommodating. Breakfast was good just need more options. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $119 CA $134 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/074573fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/4d467df2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/cb7784d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/7d430968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Mt Pleasant Charleston [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) 39.4 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1,463 reviews) "Staff was great, good breakfast options, comfortable bed and close to attractions!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristle CA $133 CA $153 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/d001db7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/3fa5d3b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/66e9726f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/3ae813f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) 37.4 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1,000 reviews) "Staff was very nice and the stay was very pleasant. Daily breakfast was on point as well. Would definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen CA $134 CA $154 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/ac1e1a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/3c942196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/88021471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/a169ee52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites at Isle Of Palms Connector [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) 37.4 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1,005 reviews) "Great location, friendly staff, good breakfast and clean and spacious rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SNEHASHNU CA $102 CA $122 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) ![Dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/abd17d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/9d83803d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/a5693308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corner King Suite with Sofa Bed](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/c632a24f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Mount Pleasant – Charleston [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) 39.9 km from Cape Romain National Wildlife Refuge 9.4/10 Exceptional (1,874 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry CA $139 CA $158 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/0b1f10c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/e93934e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/c6c81cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Balcony (Oceanfront)](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/c627c06b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palms Oceanfront Hotel [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) 37.8 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1,066 reviews) "Great staff, cute restaurants close by" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica M [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/035f9783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/c730b2f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/d70ba203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/2a58c84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Mt Pleasant Charleston [](https://www.expedia.ca/Charleston-Hotels-Home2-Suites-By-Hilton-Mt-Pleasant-Charleston.h19950102.Hotel-Information) 38.2 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1,001 reviews) "Clean room, nice staff at check in." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvia CA $134 CA $151 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Charleston-Hotels-Home2-Suites-By-Hilton-Mt-Pleasant-Charleston.h19950102.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/66c38012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/fe7118dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/9a387691.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/dc505051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Mount Pleasant Towne Centre [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Mount-Pleasant-Towne-Centre.h32131907.Hotel-Information) 37.9 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1,000 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $159 CA $196 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Mount-Pleasant-Towne-Centre.h32131907.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/f77e4dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/d3a20cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/2b0df1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/b6433898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) 37.3 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (187 reviews) "Excellent hotel. Comfortable, renovated rooms. Magnificent breakfast. Impeccable cleanliness, but the staff was not very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yaco CA $151 CA $170 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/3ba98a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/a485dcdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/90f9d74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/7d5ad2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Residences at Sweetgrass [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) 33.2 km from Cape Romain National Wildlife Refuge 8.6/10 Excellent (180 reviews) "Love it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lawanda CA $314 CA $421 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e71ca0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/651f891b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e4e88b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/c55f5199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) 39.5 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1,000 reviews) "Clean rooms, staff courteous & helpful! We loved the style of the hotel and location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $138 CA $156 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/a6beb27a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/a96ab8be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/94427b53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/1473a93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Charleston / Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) 39.7 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1,000 reviews) "Good value and great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Howard CA $145 CA $167 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) ![Cabin](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/3130f1d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/85b2e477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/02e40c2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/b32f42fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wicklow Hall [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) 27.5 km from Cape Romain National Wildlife Refuge CA $563 CA $625 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/60638c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/8dd367d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/fd5d7cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/191d7e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Charleston Mount Pleasant [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) 40.6 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1,004 reviews) "Hotel staff was very friendly and room was very spacious and clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leeat CA $128 CA $147 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/2585d9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/c149062e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/981b4538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/2f83f27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Charleston - Mt Pleasant [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) 37.2 km from Cape Romain National Wildlife Refuge 8.4/10 Very good (1,002 reviews) "Courteous staff and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Loushon CA $159 CA $182 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) ![Studio, 2 Queen Beds | Private kitchen](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/9bcf1669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/d43dbca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/61418114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/0e7d9026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites Charleston Mt. Pleasant [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) 40.6 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (525 reviews) "Staff very courteous ❤️❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane CA $127 CA $144 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/ec55154a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/22d3b448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/af6cdcf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/b58a4198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seaside Inn Oceanfront [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) 38 km from Cape Romain National Wildlife Refuge 7.6/10 Good (1,000 reviews) "Beautiful views, clean room, cozy, friendly helpful staff, great location, fun!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irene [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-07&endDate=2026-02-08®ionId=553248621532654965&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Cape Romain National Wildlife Refuge Hotel Reviews ![Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/201dd650_y.jpg) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn 10/10 Excellent "Awesome time everything was perfect " [](https://expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Seascape 317 - View! Beach! Pool!](https://images.trvl-media.com/lodging/113000000/112760000/112754600/112754586/908ea7d9_y.jpg) ### Seascape 317 - View! Beach! Pool! 10/10 Excellent "Amazing view and patio!" [](https://expedia.ca/Isle-Of-Palms-Hotels-New-Listing-Seascape-317-View-Beach-Pool.h112754586.Hotel-Information) ![Ruby's Cottage / Close to Beaches & Downtown](https://images.trvl-media.com/lodging/122000000/121740000/121735000/121734986/w1079h809x0y1-2c0db9b2_y.jpg) ### Ruby's Cottage / Close to Beaches & Downtown 10/10 Excellent "The cottage was immaculate, light and airy and comfortable. Location for us was perfect." [](https://expedia.ca/Mount-Pleasant-Hotels-Rubys-Cottage-Close-To-Beaches-Downtown.h121734986.Hotel-Information) ![Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean!](https://images.trvl-media.com/lodging/102000000/101470000/101460100/101460091/c5de9db1_y.jpg) ### Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean! 10/10 Excellent "Great view! Nice comfortable condo. Perfect for our Christmas week. The weather was perfect as well, so we could really enjoy the porch!" [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Condo-In-Wild-Dunes-Community-Pool-Great-View-Looking-At-Ocean.h101460091.Hotel-Information) !["Ocean Breeze" - Almost Ocean Front with Tons of Ocean Views - pool access](https://images.trvl-media.com/lodging/37000000/36700000/36700000/36699911/fc998cbb_y.jpg) ### "Ocean Breeze" - Almost Ocean Front with Tons of Ocean Views - pool access 10/10 Excellent "The condo was comfortable and made us feel right at home! The location was peaceful and beautiful. We thoroughly enjoyed watching the sunrise with coffee on the porch. The condo was clean, fully stocked with kitchen essentials, and had very cozy beds and linens. We would highly recommend and would love to stay again in the future! 10/10" [](https://expedia.ca/Isle-Of-Palms-Hotels-Ocean-Breeze-Almost-Ocean-Front-With-Tons-Of-Ocean-Views-Pool-Access.h36699911.Hotel-Information) ![Oceanfront 2BR, 2BA Condo in Wild Dunes! Community Pool! Great View Looking at the Atlantic Ocean!](https://images.trvl-media.com/lodging/75000000/74110000/74108000/74107927/264f746a_y.jpg) ### Oceanfront 2BR, 2BA Condo in Wild Dunes! Community Pool! Great View Looking at the Atlantic Ocean! 10/10 Excellent "Beautiful condo, perfect location " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-2BR.h74107927.Hotel-Information) ![Beautiful home with open porches overlooking lagoon in Wild Dunes](https://images.trvl-media.com/lodging/71000000/70060000/70059300/70059230/38b8716b_y.jpg) ### Beautiful home with open porches overlooking lagoon in Wild Dunes 10/10 Excellent "Property was wonderful, just needed a few more towels " [](https://expedia.ca/Isle-Of-Palms-Hotels-Beautiful-Home-With-Open-Porches-Overlooking-Lagoon-In-Wild-Dunes.h70059230.Hotel-Information) ![Mid Century Modern meets Beach Chic - Practically Oceanfront with pool access](https://images.trvl-media.com/lodging/65000000/64920000/64917500/64917428/3c85e3af_y.jpg) ### Mid Century Modern meets Beach Chic - Practically Oceanfront with pool access 10/10 Excellent "The view from the porch was wonderful! The condo was very comfortable and decorated so tastefully. The spiral staircase which led upstairs and to the lookout deck was an excellent addition. The stairs would be a challenge for several of my friends. I had everything I needed…coffee…view…great pillows…tv…wine glasses and comfortable bed! The location couldn’t be beat. I hope to stay here again. Beth communicated with me clearly and quickly. " [](https://expedia.ca/Isle-Of-Palms-Hotels-Mid-Century-Modern-Meets-Beach-Chic-Practically-Oceanfront-With-Pool-Access.h64917428.Hotel-Information) ![Port O' Call C302 - Island Retreat! Oceanview!](https://images.trvl-media.com/lodging/55000000/54640000/54634300/54634241/6445f24e_y.jpg) ### Port O' Call C302 - Island Retreat! Oceanview! 10/10 Excellent "Amazing stay!" [](https://expedia.ca/Charleston-Hotels-New-Ocean-View-Listing-Introducing-The-IOP-Island-Retreat.h54634241.Hotel-Information) ## Hotels near other Cape Romain National Wildlife Refuge attractions ![AC0TKJ The Harbor Golf Course Wild Dunes Island Resort Isle of Palms near Charleston South Carolina](https://images.trvl-media.com/place/553248621558078484/32d931cd-699d-43d6-9aa0-fa34b4c7f216.jpg) ### Wild Dunes Resort Golf Course 4.3/5 (29 reviews) Enjoy a round of golf in Isle of Palms at Wild Dunes Resort Golf Course. Stroll along the seaside in this romantic area, or check out its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078484) ![singer island florida sis fish marina palm beach shours florida sail fish marina and docks ](https://images.trvl-media.com/place/553248621558078488/715d6d03-e4d0-4a6a-ba59-71663655eb97.jpg) ### Isle of Palms Marina 4.4/5 (49 reviews) Explore the waterfront in Isle of Palms with a trip to Isle of Palms Marina. Check out the shops and top-notch restaurants in this romantic area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078488) ![Beach Front, Isle of Palms, South Carolina](https://images.trvl-media.com/place/553248621558078487/ee804706-feb1-451b-a148-6b38196711c2.jpg) ### Front Beach 4.5/5 (27 reviews) If a restful vacation is part of your travel plans, Front Beach might be the perfect place to seek out during your trip to Isle of Palms. Stroll along the seaside or visit the shops while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078487) ### Dewees Island Beach 4.1/5 (14 reviews) Why not spend a lazy afternoon at Dewees Island Beach during your trip to Isle of Palms? Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976496939) ### Charleston National Golf Club 5.0/5 (1 review) Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Check out the top-notch restaurants or lively bars in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082649) ### Goat Island Commune with nature and explore the great outdoors at Goat Island during your travels in Mount Pleasant. Amble around the area's riverfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635975748887) ### Charleston Fun Park You can take time to visit Charleston Fun Park during your travels to Mount Pleasant. Stroll along the waterfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=802133948876271616) ### Dunes West Golf and River Club 4.4/5 (83 reviews) Enjoy a round of golf in Mount Pleasant at Dunes West Golf and River Club. Check out the top-notch restaurants or lively bars in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082653) ## Frequently asked questions ### What's the area like around Cape Romain National Wildlife Refuge? ### What's the best hotel to stay close to Cape Romain National Wildlife Refuge? ### If I need to cancel the hotel reservation for my stay near Cape Romain National Wildlife Refuge, will I receive a refund? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Seaside Farms ](https://www.expedia.ca/5Star-Seaside-Farms-Mount-Pleasant-Hotels.s50-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [B&B in Awendaw ](https://www.expedia.ca/Awendaw-Bed-And-Breakfast.d3000422486-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Awendaw ](https://www.expedia.ca/Awendaw-Hotels-Cheap-Hotels.0-0-d3000422486-tCheapHotels.Travel-Guide-Filter-Hotels) - [Awendaw Hotels ](https://www.expedia.ca/Awendaw-Hotels.d3000422486.Travel-Guide-Hotels) - 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[Boutique Hotels in Marsh Island ](https://www.expedia.ca/Marsh-Island-Isle-Of-Palms-Hotels-Boutique-Hotel.0-n553248635976480509-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Marsh Island ](https://www.expedia.ca/Marsh-Island-Isle-Of-Palms-Hotels-Pet-Friendly-Hotel.0-n553248635976480509-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Farmstay in McClellanville ](https://www.expedia.ca/McClellanville-Agritourism.d183945-aaAgritourism.Travel-Guide-Accommodation) - [Cheap Hotels in McClellanville ](https://www.expedia.ca/McClellanville-Hotels-Cheap-Hotels.0-0-d183945-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in McClellanville ](https://www.expedia.ca/McClellanville-Hotels-Luxury-Hotel.0-0-d183945-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mcclellanville Hotels ](https://www.expedia.ca/McClellanville-Hotels.d183945.Travel-Guide-Hotels) - [Mount Pleasant Historic District Hotels ](https://www.expedia.ca/Mount-Pleasant-Historic-District-Mount-Pleasant-Hotels.0-n553248621557921162-0.Travel-Guide-Filter-Hotels) - 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[Pet-Friendly Hotels in Seaside Farms ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Pet-Friendly-Hotel.0-n553248635976473485-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Seaside Farms ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Ski-Hotel.0-n553248635976473485-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Seaside Farms ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Spa-Hotel.0-n553248635976473485-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Seaside Farms Hotels ](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels.0-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [Hotels near Shem Creek Park ](https://www.expedia.ca/Shem-Creek-Park-Hotels.0-l6335305-0.Travel-Guide-Filter-Hotels) - [Ski Hotels in Snee Farm ](https://www.expedia.ca/Snee-Farm-Mount-Pleasant-Hotels-Ski-Hotel.0-n553248635976470912-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Hotels near Sullivan's Island Beach ](https://www.expedia.ca/Sullivans-Island-Beach-Hotels.0-l553248635976496796-0.Travel-Guide-Filter-Hotels) - 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