Title: The 10 Best Hotels Near Cape Romain National Wildlife Refuge, | Expedia.ca [South Carolina Travel Guide](https://expedia.ca/South-Carolina.dx242)[Vacation Rentals in South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Vacation-Rental-Destinations)[Flights to South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations)[Things to do in South Carolina](https://expedia.ca/Things-To-Do-In-South-Carolina.d242.Travel-Guide-Activities)[Cape Romain National Wildlife Refuge Car Rentals](https://expedia.ca/Car-Rentals-In-Cape-Romain-National-Wildlife-Refuge.d553248621532654965.Car-Rental-Guide)[Cape Romain National Wildlife Refuge Vacations](https://expedia.ca/Cape-Romain-National-Wildlife-Refuge-South-Carolina.d553248621532654965.Vacation-Attraction) ![We had to take a ferry in the dark to get here at sunrise. They only do this at certain times during the year. I love chasing the sunrise. #adventure](https://images.trvl-media.com/place/3000422486/29abaa56-9255-457f-af06-9426eac9b0d2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by ‎‎Carla Be # Find hotels near Cape Romain National Wildlife Refuge, - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248621532654965&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Cape Romain National Wildlife Refuge ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/201dd650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/13d4a8ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/97ba3df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/f67441fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn 33.2 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1004) "Great Stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug CA $291 CA $392 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/e3cb0887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/581d948f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/fbde3014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/1d6befc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG 36.7 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1000) "Very clean and friendly staff. Great shopping and restaurants " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) adam CA $153 CA $173 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/3fa5d3b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/66e9726f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom Suite, 2 Queen Beds with Kitchen | Private kitchen](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/29153b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103200/103103/a6d131e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms 37.4 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1001) "Good stay!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda CA $131 CA $151 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-Hampton-Inn-Suites-CharlestonMt-Pleasant-Isle-Of-Palms.h103103.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/7d430968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/074573fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/69a1b766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/36000000/35820000/35810200/35810101/cc1c7e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Mt Pleasant Charleston 39.4 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1440) "Clean and friendly staff!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabitha CA $125 CA $144 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Mt-Pleasant-Charleston.h35810101.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/66c38012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/fe7118dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/dc505051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32140000/32132000/32131907/cfce3ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Mount Pleasant Towne Centre 37.9 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (1005) "Staff was great rooms clean bed comfortable Need larger bath towels " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CHARLES CA $147 CA $183 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Mount-Pleasant-Towne-Centre.h32131907.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/c6c81cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/a5dd5d0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/026d91a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/480000/477100/477018/37423c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palms Oceanfront Hotel 37.8 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1059) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nathalie [](https://www.expedia.ca/Charleston-Hotels-The-Palms-Oceanfront-Hotel.h477018.Hotel-Information) ![Luxury Cabin, Kitchen, Garden View | Private kitchen](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d1a7199e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View | Living area](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/9d6e0632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | Living area](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/d33bd814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cabin, Kitchen, Garden View](https://images.trvl-media.com/lodging/120000000/119570000/119569800/119569753/950f15d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wicklow Hall 27.5 km from Cape Romain National Wildlife Refuge CA $572 CA $629 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Georgetown-Hotels-Wicklow-Hall.h119569753.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/ac1e1a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/d9739fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/f18d338c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/520000/518300/518273/a169ee52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites at Isle Of Palms Connector 37.4 km from Cape Romain National Wildlife Refuge 8.2/10 Very good (1006) "Great big rooms and very convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) BECKY CA $123 CA $146 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Charleston-Hotels-Comfort-Suites-At-Isle-Of-Palms-Connector.h518273.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/247bf02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/9c1a9374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/c632a24f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/48d70dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Mount Pleasant – Charleston 39.8 km from Cape Romain National Wildlife Refuge 9.4/10 Exceptional (1717) "The location was very convenient and the staff was very pleasant and accommodating!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerricah CA $142 CA $163 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/f77e4dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/1c3c4bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/2b0df1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/0f73b639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Charleston Mount Pleasant 37.3 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (181) "Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Holly CA $165 CA $187 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) ![Coffee/tea maker](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/3874a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/de429beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/4f6106a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/69000000/68870000/68864000/68863938/90f9d74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Residences at Sweetgrass 33.2 km from Cape Romain National Wildlife Refuge 8.6/10 Excellent (174) "We come here often" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $296 CA $397 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Charleston-Hotels-WILD-DUNES-SWEETGRASS-RESIDENCES.h68863938.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e4e88b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/c55f5199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/7e71ca0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742817/99f7ffe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Charleston Mount Pleasant 39.5 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (1006) "Great location. Hot tub was awesome. Staff was super friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn CA $142 CA $160 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-Mount-Pleasant.h1742817.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/4deeaf46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/a96ab8be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/b00d98a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/34000000/33240000/33235800/33235721/d3883d13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Charleston / Mount Pleasant 39.7 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1008) "Rooms were very clean and the bed was extremely comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gaven CA $142 CA $160 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-House-Charleston-Mount-Pleasant.h33235721.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/6244861e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/191d7e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/58202b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690587/60638c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Charleston Mount Pleasant 40.6 km from Cape Romain National Wildlife Refuge 9.2/10 Wonderful (1026) "Well placed hotel for our stay in Charleston" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Rebecca CA $129 CA $148 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Charleston-Mount-Pleasant.h8690587.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/2a58c84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/035f9783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/82b75f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950102/58ae9bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Mt Pleasant Charleston 38.2 km from Cape Romain National Wildlife Refuge 8.8/10 Excellent (977) "Will visit again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $137 CA $154 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Charleston-Hotels-Home2-Suites-By-Hilton-Mt-Pleasant-Charleston.h19950102.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/3ffc745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/c66aafe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/51b37dff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/900000/892100/892008/e8883b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Charleston - Mt Pleasant 37.2 km from Cape Romain National Wildlife Refuge 8.4/10 Very good (1009) "This was a perfect place to stay! The staff (especially Cathy) was amazing. Walking distance from Target as well as restaurants and shopping. Loved it here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Athena CA $160 CA $183 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Charleston-Hotels-Homewood-Suites-By-Hilton-Charleston-Mt-Pleasant.h892008.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/cc1f0b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/2301806f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/0e7d9026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds | Private kitchen](https://images.trvl-media.com/lodging/20000000/19100000/19093100/19093066/9bcf1669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites Charleston Mt. Pleasant 40.6 km from Cape Romain National Wildlife Refuge 9.0/10 Wonderful (508) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) michael CA $142 CA $160 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Charleston-Hotels-TownePlace-Suites-Charleston-Mt-Pleasant.h19093066.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/078f2f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/e193d994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/af6cdcf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/120000/118600/118510/22d3b448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seaside Inn Oceanfront 38 km from Cape Romain National Wildlife Refuge 7.6/10 Good (1008) "Nice stay for the money, staff is great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamie [](https://www.expedia.ca/Charleston-Hotels-Seaside-Inn-Oceanfront.h118510.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18®ionId=553248621532654965&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Cape Romain National Wildlife Refuge Hotel Reviews ![21 Ocean Point - New to rental market](//images.trvl-media.com/lodging/94000000/93240000/93235600/93235551/ed4b45f5_y.jpg) ### 21 Ocean Point - New to rental market 10/10 Excellent "Everything was great. Had our 6 kids and 3 grandchildren with us. Worked out great. Plenty of room. Very nice place. " [](https://expedia.ca/Isle-Of-Palms-Hotels-21-Ocean-Point-New-To-Rental-Market.h93235551.Hotel-Information) ![Updated Home in Exclusive Gated Ocean Point Wild Dunes 4 min walk to Beach &Pool](//images.trvl-media.com/lodging/29000000/28770000/28767100/28767013/w637h477x3y3-0923fd80_y.jpg) ### Updated Home in Exclusive Gated Ocean Point Wild Dunes 4 min walk to Beach &Pool 10/10 Excellent "Beautiful house with anything you could need! We had a wonderful time and the host was great with communication." [](https://expedia.ca/Isle-Of-Palms-Hotels-Updated-Home-In-Exclusive-Gated-Ocean-Point-Wild-Dunes-3-Min-Walk-To-Beach-Pool.h28767013.Hotel-Information) ![Mid Century Modern meets Beach Chic - Practically Oceanfront with pool access](//images.trvl-media.com/lodging/65000000/64920000/64917500/64917428/3c85e3af_y.jpg) ### Mid Century Modern meets Beach Chic - Practically Oceanfront with pool access 10/10 Excellent "Weather was not so great but the condo was awesome " [](https://expedia.ca/Isle-Of-Palms-Hotels-Mid-Century-Modern-Meets-Beach-Chic-Practically-Oceanfront-With-Pool-Access.h64917428.Hotel-Information) ![Oceanfront 3rd Floor Condo in Wild Dunes Resort w/ Community Pool! Great Views!](//images.trvl-media.com/lodging/91000000/90930000/90929800/90929795/ef246165_y.jpg) ### Oceanfront 3rd Floor Condo in Wild Dunes Resort w/ Community Pool! Great Views! 10/10 Excellent "Absolutely beautiful place and very easy to check in,we loved the view and the beach access. The balcony is beautiful and cozy to relax or have a meal and listen to the ocean. Would definitely book again! " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-3rd-Floor-Condo-In-Wild-Dunes-Resort-W-Community-Pool-Great-Views.h90929795.Hotel-Information) ![Beautiful home with open porches overlooking lagoon in Wild Dunes](//images.trvl-media.com/lodging/71000000/70060000/70059300/70059230/38b8716b_y.jpg) ### Beautiful home with open porches overlooking lagoon in Wild Dunes 10/10 Excellent "Great House and stay! Wish the check-in process was keyless entry / self check in instead of having to pick up keys from reality office. That part seems a bit outdated, but very minor. All an all, great place, clean and as advertised. property manager communication and assistance was great. " [](https://expedia.ca/Isle-Of-Palms-Hotels-Beautiful-Home-With-Open-Porches-Overlooking-Lagoon-In-Wild-Dunes.h70059230.Hotel-Information) ![Port O' Call E303 - Sensational Top Floor View!](//images.trvl-media.com/lodging/28000000/27140000/27134400/27134370/f2be615d_y.jpg) ### Port O' Call E303 - Sensational Top Floor View! 10/10 Excellent "We absolutely loved our stay here. The beach views from the decks are incredible. Everyone we dealt with was so helpful and went above and beyond to serve us well. We will definitely be back. " [](https://expedia.ca/Charleston-Hotels-Port-O-Call-E303-Sensational-Oceanview-Top-Floor.h27134370.Hotel-Information) ![Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean!](//images.trvl-media.com/lodging/102000000/101470000/101460100/101460091/c5de9db1_y.jpg) ### Oceanfront Condo in Wild Dunes! Community Pool! Great View Looking at Ocean! 10/10 Excellent "Beautiful ocean view, well-appointed home, clean and comfortable" [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Condo-In-Wild-Dunes-Community-Pool-Great-View-Looking-At-Ocean.h101460091.Hotel-Information) ![Oceanfront Top Floor Villa, Large Balcony, & Community Pool in Wild Dunes!](//images.trvl-media.com/lodging/91000000/90930000/90929800/90929799/4ca2bcbb_y.jpg) ### Oceanfront Top Floor Villa, Large Balcony, & Community Pool in Wild Dunes! 10/10 Excellent "Very clean and spacious place. We really enjoyed the stay . Thank you " [](https://expedia.ca/Isle-Of-Palms-Hotels-Oceanfront-Top-Floor-Villa.h90929799.Hotel-Information) ![Mesmerizing Oceanfront Views! 3 Min. Walk to Quiet Beach & Community Pool w/ Cabana](//images.trvl-media.com/lodging/67000000/66090000/66090000/66089948/936dccc2_y.jpg) ### Mesmerizing Oceanfront Views! 3 Min. Walk to Quiet Beach & Community Pool w/ Cabana 10/10 Excellent "Great house and location. Had a great family trip " [](https://expedia.ca/Charleston-Hotels-Mesmerizing-Oceanfront-Views-3-Min-Walk-To-Quiet-Beach-Community-Pool-W-Hot-Tub-Cabana.h66089948.Hotel-Information) ## Hotels near other Cape Romain National Wildlife Refuge attractions [](https://www.expedia.ca/Hopsewee-Plantation-Hotels.0-l6238157-0.Travel-Guide-Filter-Hotels) ![Hopsewee Plantation showing heritage elements and a house](https://images.trvl-media.com/place/6238157/249a4dce-2116-4192-a53d-8ec14c2fa6d4.jpg) ### Hopsewee Plantation 3.2/5 (9 reviews) Relive a time when the pace of life was slow and afternoon tea was an elegant affair in this 18th-century mansion. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6238157) [](https://www.expedia.ca/Wild-Dunes-Resort-Golf-Course-Hotels.0-l553248621558078484-0.Travel-Guide-Filter-Hotels) ![AC0TKJ The Harbor Golf Course Wild Dunes Island Resort Isle of Palms near Charleston South Carolina](https://images.trvl-media.com/place/553248621558078484/32d931cd-699d-43d6-9aa0-fa34b4c7f216.jpg) ### Wild Dunes Resort Golf Course 4.3/5 (29 reviews) Enjoy a round of golf in Isle of Palms at Wild Dunes Resort Golf Course. Stroll along the beautiful beaches in this family-friendly area, or check out its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558078484) [](https://www.expedia.ca/Goat-Island-Hotels.0-l553248635975748887-0.Travel-Guide-Filter-Hotels) ### Goat Island Commune with nature and explore the great outdoors at Goat Island during your travels in Mount Pleasant. Amble around the area's riverfront or seek out the local tours. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635975748887) [](https://www.expedia.ca/Dewees-Island-Beach-Hotels.0-l553248635976496939-0.Travel-Guide-Filter-Hotels) ### Dewees Island Beach 4.1/5 (14 reviews) Why not spend a lazy afternoon at Dewees Island Beach during your trip to Isle of Palms? Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976496939) [](https://www.expedia.ca/Charleston-National-Golf-Club-Hotels.0-l6082649-0.Travel-Guide-Filter-Hotels) ### Charleston National Golf Club 5.0/5 (1 review) Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Check out the top-notch restaurants or lively bars in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082649) [](https://www.expedia.ca/Dunes-West-Golf-And-River-Club-Hotels.0-l6082653-0.Travel-Guide-Filter-Hotels) ### Dunes West Golf and River Club 4.4/5 (83 reviews) Enjoy a round of golf in Mount Pleasant at Dunes West Golf and River Club. Check out the lively bars or top-notch restaurants in this walkable area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082653) ## Frequently asked questions ### What's the area like around Cape Romain National Wildlife Refuge? > If you're planning to come to the area to visit Cape Romain National Wildlife Refuge, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, you might search for properties close to public transportation so it's easy to get around. ### What's the best hotel to stay close to Cape Romain National Wildlife Refuge? > [Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn](https://www.expedia.ca/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this resort offers 5 outdoor pools and a full-service spa. You'll find it 20.6 mi (33.2 km) from Cape Romain National Wildlife Refuge. ### If I need to cancel the hotel reservation for my stay near Cape Romain National Wildlife Refuge, will I receive a refund? > Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review top deals close to Cape Romain National Wildlife Refuge. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Seaside Farms](https://www.expedia.ca/5Star-Seaside-Farms-Mount-Pleasant-Hotels.s50-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [B&B in Awendaw](https://www.expedia.ca/Awendaw-Bed-And-Breakfast.d3000422486-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Awendaw](https://www.expedia.ca/Awendaw-Hotels-Cheap-Hotels.0-0-d3000422486-tCheapHotels.Travel-Guide-Filter-Hotels) - [Awendaw Hotels](https://www.expedia.ca/Awendaw-Hotels.d3000422486.Travel-Guide-Hotels) - [Inns in Awendaw](https://www.expedia.ca/Awendaw-Inns.d3000422486-aaInns.Travel-Guide-Accommodation) - [Resorts in Awendaw](https://www.expedia.ca/Awendaw-Resort-Hotels.d3000422486-aaResortHotels.Travel-Guide-Accommodation) - [Oceanfront Hotels in Beachwood East](https://www.expedia.ca/Beachwood-East-Isle-Of-Palms-Hotels-Oceanfront-Hotels.0-n553248635976480424-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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[Spa Hotels in Seaside Farms](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels-Spa-Hotel.0-n553248635976473485-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Seaside Farms Hotels](https://www.expedia.ca/Seaside-Farms-Mount-Pleasant-Hotels.0-n553248635976473485-0.Travel-Guide-Filter-Hotels) - [Hotels near Shem Creek Park](https://www.expedia.ca/Shem-Creek-Park-Hotels.0-l6335305-0.Travel-Guide-Filter-Hotels) - [Ski Hotels in Snee Farm](https://www.expedia.ca/Snee-Farm-Mount-Pleasant-Hotels-Ski-Hotel.0-n553248635976470912-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Hotels near Sullivan's Island Beach](https://www.expedia.ca/Sullivans-Island-Beach-Hotels.0-l553248635976496796-0.Travel-Guide-Filter-Hotels) - [Sullivan's Island Hotels](https://www.expedia.ca/Sullivans-Island-Hotels.d6161251.Travel-Guide-Hotels) - [Hotels with Kitchenettes in The Commons](https://www.expedia.ca/The-Commons-Isle-Of-Palms-Hotels-Hotels-With-Kitchenettes.0-n553248635976469553-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in The Commons](https://www.expedia.ca/The-Commons-Isle-Of-Palms-Hotels-Pet-Friendly-Hotel.0-n553248635976469553-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in Twin Oaks](https://www.expedia.ca/Twin-Oaks-Isle-Of-Palms-Hotels-Hotels-With-Free-Parking.0-n553248635976480655-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Twin Oaks Hotels](https://www.expedia.ca/Twin-Oaks-Isle-Of-Palms-Hotels.0-n553248635976480655-0.Travel-Guide-Filter-Hotels) - [Wando Hotels](https://www.expedia.ca/Wando-Hotels.d3000456159.Travel-Guide-Hotels) - [Vacation Homes in Wando](https://www.expedia.ca/Wando-Private-Vacation-Homes.d3000456159-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Rv Parks in Wando](https://www.expedia.ca/Wando-RV-Parks.d3000456159-aaRVParks.Travel-Guide-Accommodation) - [Hotels near Wild Dunes Resort Golf Course](https://www.expedia.ca/Wild-Dunes-Resort-Golf-Course-Hotels.0-l553248621558078484-0.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Yacht Harbor Court](https://www.expedia.ca/Yacht-Harbor-Court-Isle-Of-Palms-Hotels-Adults-Only-Resorts.0-n553248635976468614-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Business Hotels in Yacht Harbor Court](https://www.expedia.ca/Yacht-Harbor-Court-Isle-Of-Palms-Hotels-Business-Hotel.0-n553248635976468614-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Yacht Harbor Court Hotels](https://www.expedia.ca/Yacht-Harbor-Court-Isle-Of-Palms-Hotels.0-n553248635976468614-0.Travel-Guide-Filter-Hotels) - [Flights to Isle of Palms](https://www.expedia.ca/Cheap-Flights-To-Isle-Of-Palms.d118827.Travel-Guide-Flights) - [Flights from Awendaw](https://www.expedia.ca/lp/flights/3000422486/flights-from-awendaw) - [Blackbeard's Cove Family Fun Park](https://www.expedia.ca/Blackbeards-Cove-Family-Fun-Park-Mount-Pleasant.d6335266.Vacation-Attraction) - [Charleston National Golf Club](https://www.expedia.ca/Charleston-National-Golf-Club-Charleston-National.d6082649.Vacation-Attraction) - [Front Beach](https://www.expedia.ca/Front-Beach-Isle-of-Palms.d553248621558078487.Vacation-Attraction) - [Isle of Palms Vacations](https://www.expedia.ca/Isle-Of-Palms.d118827.Destination-Travel-Guides) - [Visit Isle of Palms](https://www.expedia.ca/Isle-Of-Palms.dx118827) - [Wild Dunes Resort Golf Course](https://www.expedia.ca/Wild-Dunes-Resort-Golf-Course-Isle-of-Palms.d553248621558078484.Vacation-Attraction) - [Car rental Isle of Palms](https://www.expedia.ca/Car-Rentals-In-Isle-Of-Palms.d118827.Car-Rental-Guide) - [Car rental Wando](https://www.expedia.ca/Car-Rentals-In-Wando.d3000456159.Car-Rental-Guide) - [Isle of Palms Vacation Rentals](https://www.expedia.ca/Isle-Of-Palms-Vacation-Rentals.d118827.Travel-Guide-VacationRentals) - [Things to do in Isle of Palms](https://www.expedia.ca/Things-To-Do-In-Isle-Of-Palms.d118827.Travel-Guide-Activities)