Title: Cape Girardeau Vacation Home Rentals from CA $138: Search Top Private Vacation Homes for Rent | Expedia.ca [Cape Girardeau Travel Guide](https://expedia.ca/Cape-Girardeau.dx820)[Hotels in Cape Girardeau](https://expedia.ca/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)[Vacation Rentals in Cape Girardeau](https://expedia.ca/Cape-Girardeau-Vacation-Rentals.d820.Travel-Guide-VacationRentals)[Flights to Cape Girardeau](https://expedia.ca/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights)[Cape Girardeau Car Rentals](https://expedia.ca/Car-Rentals-In-Cape-Girardeau.d820.Car-Rental-Guide)[Cape Girardeau Vacation Packages](https://expedia.ca/Cape-Girardeau.d820.Destination-Travel-Guides) ![Beautiful city by the Mississippi River](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Alice Burghart ![](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 12 - Jun 14](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Cape Girardeau vacation homes ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/3867ac72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish [](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) Cape Girardeau 8.4/10 Very good (50 reviews) "Cozy and perfect for a couple. Great communication with the host" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth G. CA $110 CA $138 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/469a5901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/d33a9d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/a97a55c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/211494f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool [](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information) Cape Girardeau 8.8/10 Excellent (39 reviews) "Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily D. CA $184 CA $297 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/f432dafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/0e13dd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6d0c8b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) Cape Girardeau 10/10 Exceptional (151 reviews) "Such a great place and location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy H. CA $204 CA $336 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/w1440h810x0y3-bf19009e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, foosball](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/a7fa16a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/f1c736a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, foosball](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/62582c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More [](https://www.expedia.ca/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (8 reviews) "Nice place, great times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jace W. CA $366 CA $593 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/1d4ebdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/8bdb44ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/d46d2628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/d050ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and Updated Farmhouse with King Suite [](https://www.expedia.ca/Anna-Hotels-Cozy-And-Updated-Farmhouse-With-King-Suite.h123422053.Hotel-Information) Anna 10/10 Exceptional (2 reviews) "Clean house close to Shawnee. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eileen K. CA $108 CA $201 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Anna-Hotels-Cozy-And-Updated-Farmhouse-With-King-Suite.h123422053.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/38c121bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/e63a4931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/b89da9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/a5106f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful location in the secluded woods [](https://www.expedia.ca/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) Pomona 10/10 Exceptional (64 reviews) "It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) susan B. CA $120 CA $229 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ![TV, fireplace](https://images.trvl-media.com/lodging/115000000/114220000/114217800/114217709/8315d228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114220000/114217800/114217709/474e3987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/115000000/114220000/114217800/114217709/3c93cae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114220000/114217800/114217709/6bdf4dbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny Home Cabin with Hot Tub at The Hills Campground [](https://www.expedia.ca/Cobden-Hotels-Hillside-Haven-Cabin-1.h114217709.Hotel-Information) Cobden 9.8/10 Exceptional (8 reviews) "Great little cabin and perfect for a couple getaway. Everything was close by and loved being able to walk to Feather Hills winery. Thanks for a great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David V. CA $262 CA $420 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Cobden-Hotels-Hillside-Haven-Cabin-1.h114217709.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/117000000/116290000/116288600/116288506/a1f76995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/117000000/116290000/116288600/116288506/6cc65e0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116290000/116288600/116288506/39bdfc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/117000000/116290000/116288600/116288506/24e6e51c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magical Victorian near hiking / wine trail [](https://www.expedia.ca/Anna-Hotels-Magical-Victorian-Near-Hiking-Wine-Trail.h116288506.Hotel-Information) Anna 10/10 Exceptional (5 reviews) "The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori C. CA $320 CA $573 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Anna-Hotels-Magical-Victorian-Near-Hiking-Wine-Trail.h116288506.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/b3197e50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/1c7b520a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/w1320h1474x0y0-c28d188d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/8f220eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom with AC, WiFi in lovely Jonesboro [](https://www.expedia.ca/Jonesboro-Hotels-Charming-2-Bedroom-With-AC.h118734902.Hotel-Information) Jonesboro 10/10 Exceptional (5 reviews) "great place. wonderful host." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla m. CA $158 CA $355 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Jonesboro-Hotels-Charming-2-Bedroom-With-AC.h118734902.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/809a6239.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/c405b8b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/2fc99c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/bcefe410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Farm Cottage on 800-Acre Orchard [](https://www.expedia.ca/Alto-Pass-Hotels-Farm-Immersion-Experience-At-Rendleman-Orchards.h117036792.Hotel-Information) Alto Pass 9.8/10 Exceptional (8 reviews) "What an amazing spot! Perfect weekend getaway, close to several hikes in Shawnee and we enjoyed our time on the Rendleman Orchard. Came on a girls trip, but we agreed it would be a great spot for a weekend with our partners and kids. Will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia S. CA $266 CA $332 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Alto-Pass-Hotels-Farm-Immersion-Experience-At-Rendleman-Orchards.h117036792.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/730d35eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/4183dc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/4789f71b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/32577fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass [](https://www.expedia.ca/Alto-Pass-Hotels-Walk-To-Weddings-Wineries-Trails.h121396978.Hotel-Information) Alto Pass CA $238 CA $357 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Alto-Pass-Hotels-Walk-To-Weddings-Wineries-Trails.h121396978.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/1c6c31ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/d39634e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/7dffb73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/450d2061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Building at Cape Girardeau Regional Airport [](https://www.expedia.ca/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information) Scott City CA $681 CA $829 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-02&endDate=2026-03-03®ionId=820&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_820) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.ca/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America®ionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=CABIN) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America®ionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=VACATION_HOME) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America®ionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=APARTMENT) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America®ionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=COTTAGE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCape-Girardeau-Private-Vacation-Homes.d820-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCape-Girardeau-Private-Vacation-Homes.d820-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Cape Girardeau Hotel Reviews ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "One of the newest for a new one that’s fine thank you you too thanksnicest and cleanest Fairfield Inn I have stayed at. " [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "The staff was ver accommodating love the remodel stayed 4 days could have stayed 4 more. staff is always heplful and friendly 5 \*\*\*\*\*. One issue. Its been 10 since i checked out, have not got the $50 deposit bk into my account. Thank You I will be coming bk soon" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/b002a425_y.jpg) ### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau 10/10 Excellent "My family and I stayed here over the weekend and we absolutely loved it. When we got there we felt very welcomed and at home. Chip and Busy were fantastic! Chip really is a super host. He is very welcoming and full of knowledge about the house and the area. We had an enjoyable conversation. My oldest and her friend really enjoyed talking to him too. He took his time and answered all their questions. The location is fantastic, so close to downtown. The beds were comfortable, and the kitchen has everything you could need. The place just felt very homey. The basement has an amazing soaking tub that I never wanted to get out of. I definitely plan to stay here again if I make it back to the area. Thanks again Chip, give Busy a scratch behind the ears for me!" [](https://expedia.ca/Cape-Girardeau-Hotels-Remodeled-1920s-Dutch-Colonial-Revival-In-Downtown-Cape-Girardeau.h76544096.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "room was great, clean!!" [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "Well done " [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Such a pretty hotel and the room was amazing!" [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was great. The facility was excellent. The people were excellent. Definitely going back." [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Hampton Inn Cape Girardeau I 55 East](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 10/10 Excellent "Nice staff. Clean room. Good cookies. And breakfast adequate. " [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ## Find out more about Cape Girardeau ## Cape Girardeau Vacation Homes information | Number of reviews | 330 | | ----------------- | ----------------- | | Accommodation | 66 Vacation Homes | | Lowest Price | CA $138 | | Highest Price | CA $829 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [B&B in Advance ](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Advance ](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [Advance Hotels ](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Lodges in Advance ](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance ](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - 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