Title: Book the Best ADVENTURE Hotels in Cape Girardeau in 2025 | Expedia.ca [Cape Girardeau Travel Guide](https://expedia.ca/Cape-Girardeau.dx820)[Hotels in Cape Girardeau](https://expedia.ca/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)[Vacation Rentals in Cape Girardeau](https://expedia.ca/Cape-Girardeau-Vacation-Rentals.d820.Travel-Guide-VacationRentals)[Flights to Cape Girardeau](https://expedia.ca/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights)[Cape Girardeau Car Rentals](https://expedia.ca/Car-Rentals-In-Cape-Girardeau.d820.Car-Rental-Guide)[Cape Girardeau Vacation Packages](https://expedia.ca/Cape-Girardeau.d820.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/5b27a574bbd8c4a139204e48a625a1c7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Skyy # Find Hotels & Resorts for Couples in Cape Girardeau, MO from CA $256 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cape Girardeau Hotels & Resorts for Couples Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=820&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cape Girardeau Hotels & Resorts for Couples ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6b76cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space Cape Girardeau 10/10 Exceptional (144) "Beautiful house. Great stay. Would definitely stay again!" CA $211 CA $344 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/066095c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/108eb25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/35a75be2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/2dad0af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loft Apartment Across From Semo University Houch Field House. Walk To Events Cape Girardeau 10/10 Exceptional (91) "Place is spacious and was great for a weekend in Cape. Walkable to nearby restaurants." CA $211 CA $256 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Loft-Apartment-Across-From-Semo-University-Houch-Field-House-Walk-To-Events.h19252851.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/dc959c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/54de22e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/f42a73b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/beddceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Next Door to Mercy Hospital - Pet Friendly - Fast Wifi Cape Girardeau 8.0/10 Very good (5) "Great place for our family to have a quick get together in short notice." CA $230 CA $560 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Next-Door-To-Mercy-Hospital-Pet-Friendly-Fast-Wifi.h103701368.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/d22aee4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/b0f0a7b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/6b2b149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/ded6701c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rest, Relax and Renew. Our log cabin experience awaits your arrival. Anna 10/10 Exceptional (398) "Clean comfortable cabin in a beautiful relaxing setting. Would definitely stay again." CA $164 CA $280 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anna-Hotels-Rest.h31189922.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/d6ab8f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/0b616d8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage, Multiple Beds, Non Smoking (West End Cottage)](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/a07ef7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/f6b73146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Makanda Inn Makanda 10/10 Exceptional (33) "Big thank you to the team at the cabin! Great people, great service, and great food! " CA $356 CA $406 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=820&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Cape Girardeau Hotel Reviews ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe " [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ## Frequently asked questions ### How much do hotels for couples in Cape Girardeau cost? > Prices for hotels for couples in Cape Girardeau range between CA $256 and CA $560 per night. No matter your budget, you're sure to find something to make both your partner and your pocketbook smile! This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best hotels for couples in Cape Girardeau? > Choose from multiple hotels for couples in Cape Girardeau that have a total average guest review rating of 9.5. [Drury Plaza Hotel Cape Girardeau Conference Center](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) is a recommended choice if you're searching for someplace to enjoy quality time with your partner. This 3-star escape has a swimming pool and high-speed internet services. [Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) is another leading pick that's ideal for lovebirds. It has a 2.5-star rating and amenities including a pillow top mattress and free internet services. ### How many hotels for couples are there in Cape Girardeau? > Cape Girardeau has 3 hotels for couples. To help you locate a stay that's right for you, use our handy filters to search for the amenities and perks you need. Make your next vacation with your other half the best yet with Expedia! ### Why book your hotel for couples in Cape Girardeau with Expedia? > Expedia has some terrific hotels for couples, so go ahead and spoil yourselves in Cape Girardeau. If you have a set budget, choose how much you'd like to spend and your preferred hotel star rating. Whatever your trip looks like, we'll help you find a stay that'll please both your pocket and partner! ### How can I find cheap hotels for couples in Cape Girardeau? > The best way to uncover cheap hotels for couples in Cape Girardeau is with Expedia's easy-to-use filter tool. Refine your search by star rating, amenities and budget and nab awesome prices on getaways where you can kick back with your partner. ### What is there to do in Cape Girardeau near my hotel for couples? > Cape Girardeau has enough sights and activities to keep you on the go for weeks (or months!), starting with [Cape Splash Family Aquatic Center](https://www.expedia.ca/Cape-Splash-Family-Aquatic-Center-Cape-Girardeau.d553248621532655772.Vacation-Attraction). [Hunter Valley Winery](https://www.expedia.ca/Hunter-Valley-Winery-Cape-Girardeau.d553248621532655783.Vacation-Attraction), [Lazy L Safari Park](https://www.expedia.ca/Lazy-L-Safari-Park-Cape-Girardeau.d553248621532655782.Vacation-Attraction) and [Isle Casino Cape Girardeau](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction) are other fantastic attractions. 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[Flights from Accra (ACC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/acc/cgi/accra-to-cape-girardeau) - [Flights from Bloomington (BMI) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/bmi/cgi/bloomington-to-cape-girardeau) - [Flights from Buffalo (BUF) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/buf/cgi/buffalo-to-cape-girardeau) - [Flights from Colombo (CMB) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/cmb/cgi/colombo-to-cape-girardeau) - [Flights from Dhaka (DAC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/dac/cgi/dhaka-to-cape-girardeau) - [Flights from Grand Island (GRI) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/gri/cgi/grand-island-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from Las Vegas (LAS) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/las/cgi/las-vegas-to-cape-girardeau) - 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[Flights from Toronto (YYZ) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yyz/cgi/toronto-to-cape-girardeau) - [Eden Spa & Salon](https://www.expedia.ca/EDen-Spa-Salon-Cape-Girardeau.d553248621532655776.Vacation-Attraction) - [Southeast Missouri State University](https://www.expedia.ca/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) - [Rental cars Cape Girardeau Municipal airport](https://www.expedia.ca/Car-Rentals-In-Cape-Girardeau-Municipal.d6026978.Car-Rental-Guide) - [Car rentals near Cape Girardeau County](https://www.expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Rental-Destinations) - [Hertz Rental Cars in Marble Hill](https://www.expedia.ca/Hertz-Car-Rentals-In-Marble-Hill.d3000445212-c40.Car-Rental-Guide-Suppliers) - [Marble Hill Vacation Rentals](https://www.expedia.ca/Marble-Hill-Vacation-Rentals.d3000445212.Travel-Guide-VacationRentals) - [Book Hotels & Resorts for Couples in Cape Girardeau on Expedia.com](https://www.expedia.com/Cape-Girardeau-Hotels-Couples-Resorts-Hotels.0-0-d820-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)