Title: Hotels by Hilton Hotels in Byron from CA $274 | Expedia.ca

[Byron Travel Guide](https://expedia.ca/Byron.dx553248623858895563)[Hotels in Byron](https://expedia.ca/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels)[Vacation Rentals in Byron](https://expedia.ca/Byron-Vacation-Rentals.d553248623858895563.Travel-Guide-VacationRentals)[Flights to Byron](https://expedia.ca/Cheap-Flights-To-Byron.d553248623858895563.Travel-Guide-Flights)[Byron Car Rentals](https://expedia.ca/Car-Rentals-In-Byron.d553248623858895563.Car-Rental-Guide)[Byron Vacation Packages](https://expedia.ca/Byron.d553248623858895563.Destination-Travel-Guides)

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## Check prices for these dates

Tonight

[Jan 20 - Jan 21](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-01-20&endDate=2026-01-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Jan 21 - Jan 22](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-01-21&endDate=2026-01-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Byron Hilton Hotels

![Presidential Suite, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/ef0f8d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 5:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/74161f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Rochester Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information)

Downtown Rochester

9.6/10

Exceptional

(553 reviews)

"Very courteous staff, loved the valet guy!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jean

CA $238

CA $274 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Byron Hotel Reviews

![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07_y.jpg)

### The Berkman

10/10 Excellent

"Amazing"

[](https://expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information)

![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Love the restaurant… truffle fries are the best!!! Staff is great!!!"

[](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg)

### Kahler Grand Hotel

10/10 Excellent

"The amenities and the great customer service. "

[](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg)

### AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"Very helpful staff. Wasn't able to try breakfast due to my schedule"

[](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information)

![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg)

### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"Clean room...helpful staff. Thank you for a great experience. "

[](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information)

![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg)

### Home2 Suites by Hilton Rochester Mayo Clinic Area

10/10 Excellent

"The room was clean. The staff was excellent. We enjoyed our stay."

[](https://expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg)

### Aspen Suites

10/10 Excellent

"I stayed here for 2+ months this past summer when my daughter had her heart transplant and they became like family to me and they helped me get through it. We were back this past week for my daughters check up and as usual everything and everyone was wonderful. The breakfast food was fresh and delicious. The staff is the best ever. The room was spotless and so comfortable. The entire place is homey and cozy. It is our home away from home. Thank you so much guys ♥️"

[](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg)

### Hampton Inn Rochester-South

10/10 Excellent

"Small rooms yet workable"

[](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg)

### Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"The electrical outlet plugs in the room were worn out. Most would not hold a plug. Plug in their hair dryer or the brick to charge my phone and it would just drop out of the socket. Frustrating and especially in the bathroom NOT SAFE. The room was worn but meticulously clean. "

[](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information)

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