Title: Hotels by La Quinta Inn & Suites in Byrnes Mill from CA $141 | Expedia.ca [Byrnes Mill Travel Guide](https://expedia.ca/Byrnes-Mill.dx553248634983534850)[Hotels in Byrnes Mill](https://expedia.ca/Byrnes-Mill-Hotels.d553248634983534850.Travel-Guide-Hotels)[Vacation Rentals in Byrnes Mill](https://expedia.ca/Byrnes-Mill-Vacation-Rentals.d553248634983534850.Travel-Guide-VacationRentals)[Flights to Byrnes Mill](https://expedia.ca/Cheap-Flights-To-Byrnes-Mill.d553248634983534850.Travel-Guide-Flights)[Byrnes Mill Car Rentals](https://expedia.ca/Car-Rentals-In-Byrnes-Mill.d553248634983534850.Car-Rental-Guide)[Byrnes Mill Vacation Packages](https://expedia.ca/Byrnes-Mill.d553248634983534850.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Byrnes Mill from CA $141 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 23 - Sep 24](https://www.expedia.ca/Hotel-Search?regionId=553248634983534850&startDate=2025-09-23&endDate=2025-09-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=553248634983534850&startDate=2025-09-24&endDate=2025-09-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983534850&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248634983534850&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Byrnes Mill La Quinta Inn & Suites Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/62900/62842/2d27fd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/70000/62900/62842/36ebecda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/62900/62842/b4f579c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/62900/62842/78aa66ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham St. Louis Westport Maryland Heights 7.2/10 Good (1054) "Great stay" CA $122 CA $141 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Louis-Westport.h62842.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/3c134c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/f5fc6a89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/9bd5c64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/c1b448b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham St Louis Route 66 St. Louis 7.8/10 Good (1006) "Great stay" CA $142 CA $165 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Louis-Route-66.h546395.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/a1c40704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/e9e97147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South Festus 8.0/10 Very good (856) "Great easy place to stay. Good location." CA $140 CA $160 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-07&endDate=2025-10-08®ionId=553248634983534850&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FByrnes-Mill-Hotels-La-Quinta-Inn-Suites.0-0-d553248634983534850--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FByrnes-Mill-Hotels-La-Quinta-Inn-Suites.0-0-d553248634983534850--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Byrnes Mill Hotel Reviews ![Drury Plaza Hotel St. Louis Chesterfield](//images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/c1fcfc39_y.jpg) ### Drury Plaza Hotel St. Louis Chesterfield 10/10 Excellent "Probably the nicest hotel we've stayed in! Everyone was so nice and accommodating. A treat bag for our pup, free dinner, free drinks, and free breakfast?!? Pool was indoor and outdoor!! Amazing!" [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![The Cheshire](//images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de_y.jpg) ### The Cheshire 10/10 Excellent "Great stay…loved the atmosphere. Unique and fun. " [](https://expedia.ca/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](//images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Breakfast was great. Rooms super clean and plenty of parking." [](https://expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![The Wildwood Hotel](//images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg) ### The Wildwood Hotel 10/10 Excellent "A great experience Staff is helpful and truly proud of their hotel. A very pleasant stay in classy environment. " [](https://expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Sonesta ES Suites St. Louis - Chesterfield](//images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e_y.jpg) ### Sonesta ES Suites St. Louis - Chesterfield 10/10 Excellent "Best breakfast options" [](https://expedia.ca/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information) ![AC Hotel St. Louis Clayton](//images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/4a44ac13_y.jpg) ### AC Hotel St. Louis Clayton 10/10 Excellent "Room was new and clean. 11th floor bar was fun. Breakfast was good and supposed to be included but I had to ask twice to make that happen. Parking does cost extra. I would stay here again, overall it was a good experience. " [](https://expedia.ca/St-Louis-Hotels-Ac-Hotel-By-Marriott-St-Louis-Clayton.h105374473.Hotel-Information) ![Courtyard by Marriott St Louis Creve Coeur](//images.trvl-media.com/lodging/1000000/20000/11100/11052/96f17f89_y.jpg) ### Courtyard by Marriott St Louis Creve Coeur 10/10 Excellent "Very clean, friendly staff. " [](https://expedia.ca/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Creve-Coeur.h11052.Hotel-Information) ![Best Western St. Louis Inn](//images.trvl-media.com/lodging/1000000/70000/63700/63684/00b04c50_y.jpg) ### Best Western St. Louis Inn 10/10 Excellent "Clean, quiet, up to date, friendly staff, decent hot breakfast, gym was pretty good for a hotel gym. Would stay here again and recommend. There for a friend's wedding." [](https://expedia.ca/St-Louis-Hotels-Best-Western-St-Louis-Inn.h63684.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](//images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Very good hotel " [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Aparthotels in Barnhart](https://www.expedia.ca/Barnhart-Apart-Hotels.d6354572-aaApartHotels.Travel-Guide-Accommodation) - [Barnhart Hotels](https://www.expedia.ca/Barnhart-Hotels.d6354572.Travel-Guide-Hotels) - [Townhomes in Barnhart](https://www.expedia.ca/Barnhart-Townhomes.d6354572-aaTownhomes.Travel-Guide-Accommodation) - [Rv Parks in Cedar Hill Lakes](https://www.expedia.ca/Cedar-Hill-Lakes-RV-Parks.d553248634983253022-aaRVParks.Travel-Guide-Accommodation) - 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[Flights to Fenton](https://www.expedia.ca/Cheap-Flights-To-Fenton.d7150.Travel-Guide-Flights) - [Six Flags St. Louis](https://www.expedia.ca/Six-Flags-St-Louis-St-Louis.d6147083.Vacation-Attraction) - [Car rental Pacific](https://www.expedia.ca/Car-Rentals-In-Pacific.d9043.Car-Rental-Guide) - [Car rentals near Route 66 State Park](https://www.expedia.ca/Car-Rentals-In-Route-66-State-Park.d6292976.Car-Rental-Guide) - [Luxury Car Rentals near Route 66 State Park](https://www.expedia.ca/Luxury-Car-Rentals-In-Route-66-State-Park.d6292976-tLuxury.Car-Rental-Guide-Class) - [Pickup Car Rentals near Show Me](https://www.expedia.ca/Pickup-Car-Rentals-In-Show-Me.d553248635996618251-tPickup.Car-Rental-Guide-Class) - [Things to do in Eureka](https://www.expedia.ca/Things-To-Do-In-Eureka.d7020.Travel-Guide-Activities) - [Things to do in High Ridge](https://www.expedia.ca/Things-To-Do-In-High-Ridge.d553248634983579370.Travel-Guide-Activities) - [Book La Quinta Inn & Suites in Byrnes Mill on Expedia.com](https://www.expedia.com/Byrnes-Mill-Hotels-La-Quinta-Inn-Suites.0-0-d553248634983534850--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)