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Our top choices for Buffalo hotels

A hotel room with a bed, a sofa, a nightstand, and a small table.
A row of residential buildings with a blue door, a white window, and a vent on the wall.
A rectangular pool with a blue border, surrounded by a black fence. There are lounge chairs and a small table with chairs along the poolside.
A reception area with a blue wall, a wooden counter, a glass door leading outside, and a potted plant.

1. Rodeway Inn Union

Rodeway Inn Union
Union
United States
Dejuana
CA $92
CA $100 total
includes taxes & fees
Oct 22 - Oct 23
Rodeway Inn Union
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A hotel room with a wooden table, a black office chair, a black refrigerator, and a large mirror on the wall.
A building with a sign for "The Night Inn" featuring a stylized 'N' logo.
A motel with a single-story structure, a covered parking area, and a well-maintained lawn.

2. The Night Inn

The Night Inn
Union
United States
Robert
CA $92
CA $109 total
includes taxes & fees
Oct 4 - Oct 5
The Night Inn
A hotel room with a bed, bedside table, chair, desk, television, and a painting on the wall.
A modern kitchen with grey cabinets, a granite countertop, and a breakfast bar. There are various appliances like a coffee maker, microwave, and waffle maker.
A swimming pool with a fenced area, a covered seating area, and a building with a staircase and a door.
A two-story motel with a covered parking area and a clear sky.

3. Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26
Clinton
United States
Tyiesha
CA $105
CA $123 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Clinton - Laurens I-26
A modern indoor space with a sofa, tables, chairs, and a pool view.
A modern interior with a stone fireplace, wooden tables and chairs, and a large orange sofa.
A pool area with a clear view of the outdoors, including a patio with chairs and umbrellas.
A gym with treadmills, weight machines, and a mirror reflecting the equipment.

4. Hampton Inn & Suites Clinton - I-26

Hampton Inn & Suites Clinton - I-26
Clinton
United States
Andrea
CA $187
CA $210 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Clinton - I-26
A hotel with a central entrance, multiple floors, and a flag display.
A hotel room with a bed, a sofa, a coffee table, two lamps, a framed picture, and a mirror.
A hotel room with a desk, chair, bed, and a bathroom with a sink and mirror.
A hotel reception area with a modern reception desk, seating area, and large windows.

5. Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College
Clinton
United States
alberto
CA $138
CA $159 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites Clinton near Presbyterian College
A modern lobby with a reception desk, seating area, and a television screen.
A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.
A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.
A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

6. Best Western Spartanburg I-26

Best Western Spartanburg I-26
Spartanburg
United States
Santhosh
CA $144
CA $160 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Spartanburg I-26
A modern living room with a sofa, armchairs, a patterned rug, and a Buddha statue.
A swimming pool with a lifeguard chair, a shallow water sign, and a no diving allowed sign.
A hotel room with two beds, a sofa, a TV, and a window with curtains.
A laundry room with a washing machine, dryer, chair, and table.

7. Days Inn by Wyndham Clinton / Laurens I-26

Days Inn by Wyndham Clinton / Laurens I-26
Clinton
United States
Julian
CA $96
CA $108 total
includes taxes & fees
Oct 24 - Oct 25
Days Inn by Wyndham Clinton / Laurens I-26
An outdoor seating area with sofas, a fire pit, and string lights.
A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.
A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.
A modern interior with hanging chairs, tables, and a view of the parking lot.

8. Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
Spartanburg
United States
Anthony
CA $150
CA $167 total
includes taxes & fees
Nov 1 - Nov 2
Tru by Hilton Spartanburg
A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.
A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.
A food service counter with a sign that reads "EXPRESS START".
A hotel reception area with a wooden reception desk, a receptionist, and a revolving door.

9. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Spartanburg
United States
Michael
CA $141
CA $156 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.
A lobby with a stone fireplace, sofas, a TV mounted on the wall, and a bar area in the background.
A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.
A modern kitchen with marble countertops, wooden shelves, and a wine station.

10. Spartanburg Marriott

Spartanburg Marriott
Spartanburg
United States
Daniel
CA $168
CA $186 total
includes taxes & fees
Nov 1 - Nov 2
Spartanburg Marriott
A bar area with a long counter, multiple stools, and shelves stocked with bottles.
A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.
A restaurant with a central island seating area, multiple tables, and a large mural on the wall.
An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

11. Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
Spartanburg
United States
Yuliya
CA $186
CA $207 total
includes taxes & fees
Oct 30 - Oct 31
Hilton Garden Inn Spartanburg
A dining area with tables and chairs, a television mounted on the wall, and a kitchen area with appliances.
A Rodeway Inn with a two-story building, a parking lot, and a few cars parked in front.
A hotel lobby with a reception desk, seating area, and a television.
A hotel room with patterned green sofas, a wooden table, and a green wall.

12. Rodeway Inn Laurens

Rodeway Inn Laurens
Laurens
United States
Ellamae
CA $100
CA $112 total
includes taxes & fees
Oct 25 - Oct 26
Rodeway Inn Laurens
A two-story building with a red roof and a sign for Red Roof Inn & Suites.
A two-story Red Roof Inn with a flat roof, multiple windows, and a sign indicating it offers suites.
A hotel room with two beds, a TV, a desk, and a bathroom door.
A laundry room with two washing machines and a dryer, a door, and a tiled floor.

13. Red Roof Inn Spartanburg - I-85

Red Roof Inn Spartanburg - I-85
Spartanburg
United States
Walker
CA $92
CA $102 total
includes taxes & fees
Oct 8 - Oct 9
Red Roof Inn Spartanburg - I-85
A modern kitchen with a central island, bar stools, and pendant lighting.
A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.
A hotel lobby with a reception desk, seating area, and large windows.
A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

14. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Spartanburg
United States
Bogdan
CA $156
CA $173 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.
A gym with treadmills, elliptical machines, and weight machines.
A hotel room with a desk, office chair, sofa, and a large wall art piece.
A modern lobby with blue sofas, a reception desk, and a glass coffee table.

15. Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
Spartanburg
United States
tara
CA $129
CA $143 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites At WestGate Mall
A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.
A modern hotel with a prominent Fairfield sign, multiple floors, and a well-lit entrance.
A modern dining area with wooden flooring, round tables, and chairs. There are wall-mounted artworks and a sign that reads "LESS MONDAY MORE SUMMER".
A modern lobby with a sofa, armchairs, and a coffee table. There is a reception desk and a dining area in the background.

16. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown
Spartanburg
United States
Pemberton
CA $186
CA $207 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield by Marriott Inn & Suites Spartanburg Downtown
A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.
A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.
A modern restaurant with a bar area, high ceilings, and a view of the cityscape.
A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.

17. AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
Spartanburg
United States
Willow
CA $240
CA $267 total
includes taxes & fees
Oct 11 - Oct 12
AC Hotel by Marriott Spartanburg
A hotel room with a bed, a desk with a computer, a television, and a microwave.
A bedroom with a bed, wooden headboard, bedside tables, and a ceiling light.
A room with two beds, each with a wooden headboard and a floral bedspread. There is a small wooden table beside the beds.
A single-story motel with a flat roof, large windows, and a small porch area.

18. SUN AND SAND MOTEL

SUN AND SAND MOTEL
Spartanburg
United States
Jeffrey
CA $94
CA $105 total
includes taxes & fees
Oct 5 - Oct 6
SUN AND SAND MOTEL
A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.
A vending area with various snack and drink options, including chips, sodas, and bottled water.
A hotel room with a kitchenette, two beds, a red sofa, and a dining area.
An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.

19. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Spartanburg
United States
Amy
CA $145
CA $161 total
includes taxes & fees
Oct 31 - Nov 1
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
A modern breakfast area with a blue-tiled backsplash, a coffee station, and seating with teal cushions.
A reception area with a modern design, featuring a stone wall, two reception desks, and a potted plant.
A hotel room with a large bed, a desk with a chair, a television, and a window with curtains.
A bathroom with a granite countertop sink, a large mirror, a microwave, and a coffee maker.

20. Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest
Spartanburg
United States
CYNTHIA
CA $105
CA $117 total
includes taxes & fees
Nov 1 - Nov 2
Sleep Inn Spartanburg Southwest
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Top Buffalo Hotel Reviews

Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown

10/10 Excellent
"Great breakfast option!"
Zachary 2-night trip
Posted less than an hour ago
Fairfield by Marriott Inn & Suites Spartanburg Downtown
Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College

10/10 Excellent
"I was a guest for two weeks. The staff was very friendly and made a great effort to make my stay feel safe and comfortable. The beds were SO comfortable and soft. Breakfast was good. I’d definitely stay there again for future visits to Clinton SC."
Kimber 9-night trip
Posted 5 hours ago
Comfort Suites Clinton near Presbyterian College
Best Western Spartanburg I-26

Best Western Spartanburg I-26

10/10 Excellent
"The gentleman working the desk was very kind. We were out having breakfast and he just stopped to make sure it was good or if we needed anything. Very clean room. Surprisingly quiet for being so close to the interstate. 10:10 will stay here when we travel through again!"
Heather 1-night trip
Posted 6 hours ago
Best Western Spartanburg I-26
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent
"From the check -in to check- out, everything and everyone was top notch!"
Amy 1-night trip
Posted 1 day ago
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

10/10 Excellent
"The hotel was clean and so well landscaped. We really enjoyed the restaurant. The only thing is that when we asked for towels , we had to go get them after we asked twice. also the clerk must have many tasks because the one person manning the desk was not readily available. We had to wait several times for their return. Thank you for the complimentary bottled water."
Darlene 6-night trip
Posted 2 days ago
Hilton Garden Inn Spartanburg
Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26

10/10 Excellent
"I stay here a lot. As always, they are great. Good people, clean room!!"
Matthew 1-night trip
Posted 3 days ago
Quality Inn Clinton - Laurens I-26
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

8/10 Good
"Breakfast was not the best"
Tim 1-night trip
Posted 4 days ago
Sleep Inn Spartanburg Southwest
Spartanburg Marriott

Spartanburg Marriott

10/10 Excellent
"Professional and polite staff, the grounds were well maintained, ample useful and attractive all while being well located for my purposes."
Daniel 2-night trip
Posted 4 days ago
Spartanburg Marriott

More cheap stays in Buffalo

Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

501 South Blackstock Rd Spartanburg SC
CA $105
CA $117 total
Nov 1 - Nov 2
includes taxes & fees
6/10 (651 reviews)
Sleep Inn Spartanburg Southwest
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC
CA $129
CA $143 total
Nov 1 - Nov 2
includes taxes & fees
Comfort Suites At WestGate Mall
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC
CA $141
CA $156 total
Nov 1 - Nov 2
includes taxes & fees
8.6/10 Excellent! (1,001 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College

12865 Hwy 56 N Clinton SC
CA $138
CA $159 total
Nov 1 - Nov 2
includes taxes & fees
8/10 Very good! (811 reviews)
Comfort Suites Clinton near Presbyterian College
Best Western Spartanburg I-26

Best Western Spartanburg I-26

488 South Blackstock Road Spartanburg SC
CA $144
CA $160 total
Oct 11 - Oct 12
includes taxes & fees
9.4/10 Exceptional! (49 reviews)
Best Western Spartanburg I-26
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

103 Franklin Avenue Spartanburg SC
CA $150
CA $167 total
Nov 1 - Nov 2
includes taxes & fees
Tru by Hilton Spartanburg

Hotels in Buffalo with star rating

Frequently asked questions

What is the best area to stay in Buffalo?
The best area to stay in Buffalo, South Carolina, is near the intersection of Main Street and South Carolina Highway 215, as this is the most developed part of the town.This central area offers the most convenience for visitors. You'll find the Buffalo Post Office and a few local shops and eateries clustered around this junction. It's a small, rural community, and this intersection serves as its commercial heart.For solo travellers or couples looking for a quiet retreat, staying in this area provides easy access to the local amenities and a sense of the community.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Buffalo.
How much is the nightly rate at a Buffalo hotel?
Prices for hotels in Buffalo often vary, but you can find a great deal from CA $100 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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