The best area to stay in Brinkley is near the intersection of US-70 and US-49, particularly around the I-40 interchange.This area is the primary commercial hub of Brinkley, offering the most convenience for travellers. You'll find a concentration of hotels, restaurants, and essential services along US-70, especially as it crosses I-40. It's a practical and straightforward layout, designed for easy access for those passing through.For families or those on a road trip, this area is ideal. Its direct access to I-40 makes it an excellent overnight stop, minimising detours.