Title: Book the Best BUSINESS Hotels in Blythewood in 2026 | Expedia.ca [Blythewood Travel Guide](https://expedia.ca/Blythewood.dx180657)[Hotels in Blythewood](https://expedia.ca/Blythewood-Hotels.d180657.Travel-Guide-Hotels)[Vacation Rentals in Blythewood](https://expedia.ca/Blythewood-Vacation-Rentals.d180657.Travel-Guide-VacationRentals)[Flights to Blythewood](https://expedia.ca/Cheap-Flights-To-Blythewood.d180657.Travel-Guide-Flights)[Things to do in Blythewood](https://expedia.ca/Things-To-Do-In-Blythewood.d180657.Travel-Guide-Activities)[Blythewood Car Rentals](https://expedia.ca/Car-Rentals-In-Blythewood.d180657.Car-Rental-Guide)[Blythewood Vacation Packages](https://expedia.ca/Blythewood.d180657.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Blythewood, SC from CA $111 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Blythewood Business Hotels Tonight [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=180657&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=180657&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=180657&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=180657&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Blythewood business-friendly hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/330000/327400/327375/7e4ec273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/330000/327400/327375/c90ed53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327400/327375/f2a47558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/330000/327400/327375/w1932h1152x18y29-440477c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Blythewood - North Columbia Blythewood 7.6/10 Good (1003) "welcoming staff, clean rooms and plenty of free parking" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $116 CA $130 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Columbia-Hotels-Comfort-Inn-Blythewood-North-Columbia.h327375.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/430000/424300/424276/24425a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/430000/424300/424276/a75630ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424300/424276/be67c8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/430000/424300/424276/1f60ee93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Blythewood by IHG Blythewood 8.6/10 Excellent (1004) "Friendly staff and breakfast was delicious! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krista CA $158 CA $177 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Blythewood.h424276.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/70000000/69310000/69305800/69305778/bf835e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69310000/69305800/69305778/52b4219a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69310000/69305800/69305778/9c7bde0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69310000/69305800/69305778/ace4a6d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Blythewood, SC Blythewood 8.8/10 Excellent (308) "Love this hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chrystal CA $187 CA $210 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Columbia-Hotels-Home2-Suites-By-Hilton-Blythewood.h69305778.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/470d616b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/33d87b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, Refreshed Deluxe Room, Non-Smoking](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/71345cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson Columbia 7.6/10 Good (1008) "Great breakfast and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean CA $99 CA $111 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/45d8f751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/0a695ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/7b635fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Columbia/Harbison Columbia 9.0/10 Wonderful (1868) "This property and their staff were lovely!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $109 CA $123 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91920000/91916600/91916506/b5706b38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/92000000/91920000/91916600/91916506/1b5eb5f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible (Communications)](https://images.trvl-media.com/lodging/92000000/91920000/91916600/91916506/7b690447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91920000/91916600/91916506/5952207c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Lexington by IHG Lexington 9.4/10 Exceptional (272) "Great service! Beautiful hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andryel CA $151 CA $168 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Lexington-Hotels-Holiday-Inn-Express-Lexington.h91916506.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/c0bcb33a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/87830651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/7d6c02d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/7cb8c23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia Airport, SC Cayce 8.2/10 Very good (1000) "Clean and friendly staff easy check in and out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $124 CA $138 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1160796.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36270000/36264300/36264221/f92cb7f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36270000/36264300/36264221/4dab3e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed](https://images.trvl-media.com/lodging/37000000/36270000/36264300/36264221/c3046ad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/37000000/36270000/36264300/36264221/58340db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Columbia - Downtown by IHG Downtown Columbia 8.8/10 Excellent (697) "Great place and location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $106 CA $119 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Columbia-Downtown.h36264221.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/9eb183a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/485b8fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/e288e3a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/191bc09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Columbia Cayce Cayce 9.0/10 Wonderful (651) "Room was clean. staff was very pleasant. Cafe / Bistro was good and convenient. Easy parking on site." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joan CA $140 CA $155 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Cayce.h17369973.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34920000/34915100/34915089/a6ac2edc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34920000/34915100/34915089/c3e9d6eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34920000/34915100/34915089/62813f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible (Roll-In Shower)](https://images.trvl-media.com/lodging/35000000/34920000/34915100/34915089/1b727f0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Camden Camden 9.2/10 Wonderful (354) "Clean hotel and dog friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randall CA $176 CA $197 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Columbia-Hotels-Hampton-Inn-Camden.h34915089.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-23&endDate=2025-12-24®ionId=180657&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Blythewood Hotel Reviews ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Room was very clean and amazingly comfy. This was our 3rd time staying and we'll be sure to stay again ❤️" [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "." [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "The rooms were clean and well kept and the beds were very comfortable. It was quiet at night and the blinds kept the room nicely dark. Breakfast was fantastic with lots of choices and the staff was friendly and helpful. We'll definitely stay there again!" [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Hyatt Place Columbia/Harbison](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/68fe8568_y.jpg) ### Hyatt Place Columbia/Harbison 10/10 Excellent "GREAT STAFF LOVED THE STAY WOULD BOOK AGAIN 💙" [](https://expedia.ca/Columbia-Hotels-Hyatt-Place-ColumbiaHarbison.h327027.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "The room was clean and the staff was nice and respectful. I will stay again!!" [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Everything was wonderful! Staff, parking, location, bar, and pillows !" [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Baymont by Wyndham Columbia Fort Jackson](https://images.trvl-media.com/lodging/1000000/580000/574500/574461/c68af965_y.jpg) ### Baymont by Wyndham Columbia Fort Jackson 10/10 Excellent "Clean, breakfast was good, but the second day I went to eat with my family around 8am and everything was gone. Only one tray or eggs and bacon for so many guesses is unacceptable. I asked the lady at the reception and she told me that she is working solo and that was it. Tbh she needed help. " [](https://expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Fort-Jackson.h574461.Hotel-Information) ![Comfort Inn Blythewood - North Columbia](https://images.trvl-media.com/lodging/1000000/330000/327400/327375/7e4ec273_y.jpg) ### Comfort Inn Blythewood - North Columbia 10/10 Excellent "Enjoyed my stay" [](https://expedia.ca/Columbia-Hotels-Comfort-Inn-Blythewood-North-Columbia.h327375.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, SC](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "I was greeted by a friendly and polite front staff. My room was clean with comfortable bed and hot shower. " [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Blythewood cost? ### What are the best business-friendly hotels in Blythewood? ### How many business-friendly hotels are there in Blythewood? ### What are the best cheap business-friendly hotels in Blythewood? ### Why book your business-friendly hotel in Blythewood with Expedia? ### How can I find cheap business-friendly hotels in Blythewood? ### What is there to do in Blythewood near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in South Carolina Midlands ](https://www.expedia.ca/4Star-South-Carolina-Midlands-Hotels.s40-0-d6057938.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes ](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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