Title: 10 Best Hotels in Santa Ana, Antigua Guatemala for 2025 | Expedia.ca

 

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![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Hotels in Santa Ana, Antigua Guatemala

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## Go beyond your typical stay in Santa Ana

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&amenities=SPA_ON_SITE)

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&lodging=APART_HOTEL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&travelerType=family_friendly)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&amenities=HOT_TUB)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&lodging=APARTMENT)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&amenities=POOL)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&amenities=PETS)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&lodging=CABIN)

## Check prices for these dates

Tonight

[Nov 6 - Nov 7](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-11-06&endDate=2025-11-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 7 - Nov 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-11-07&endDate=2025-11-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Santa Ana hotels and places to stay

![Interior](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2c2e8198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/263c7d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/1914e3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2499f453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Buho B&B

Santa Ana

9.2/10

Wonderful

(46)

"All was very good and True to the pictures "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Xavier

CA $79

CA $96 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information)

![Garden view](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/4afb3fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room, Garden View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/d65461db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/e33ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Twin Room, Balcony, City View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/f4dd18dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal Casa Buho

Santa Ana

8.6/10

Excellent

(21)

"Las instalaciones están muy bien solo que sí está lejos del centro de Antigua "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

LUIS FERNANDO

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/07c82154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/1937b53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, 4 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/e93ede8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, Accessible, Mountain View | Private kitchen](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/59cb6c23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villas Santa Ana-Ricardo

Santa Ana

8.4/10

Very good

(11)

"We loved this house the view was wonderful "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emely

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/08e02f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Triple Room, Non Smoking](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/c95cec25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/fee845e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/f906119c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La guarida del caudillo

Santa Ana

CA $35

CA $44 total

includes taxes & fees

Nov 8 - Nov 9

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-La-Guarida-Del-Caudillo.h107726544.Hotel-Information)

![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/0a6e1626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/53c546cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Airport shuttle](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/4cb26f2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Barceló Guatemala City

22.7 km from Santa Ana

9.2/10

Wonderful

(3075)

"I bring an rental car amd parking lot is excellent and secured. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Estuardo

CA $114

CA $140 total

includes taxes & fees

Dec 8 - Dec 9

[](https://www.expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![3 outdoor pools, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/93bfa68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/cc442321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/a9206ed9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/02246420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Soleil La Antigua

1.8 km from Santa Ana

8.6/10

Excellent

(1001)

"Great place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Edwin

CA $236

CA $288 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information)

![Fitness studio](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Building design](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/082f03cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/26d4f3dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room (All rooms are different)](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/7b28f528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción, 1.1 km from Santa Ana

9.2/10

Wonderful

(1002)

"This is an incredible property, historic, beautiful, the best one in antigua, i highly recommend it."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Allam

CA $381

CA $482 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/014bd4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/331b5eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/ae6d736c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Master Suite](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/3cede885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Los Pasos Boutique Hotel & Spa

0.7 km from Santa Ana

9.4/10

Exceptional

(1001)

"Super Clean, very attentive staff, restaurant very nice, clean and food was delicious."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dolores

CA $196

CA $241 total

includes taxes & fees

Dec 8 - Dec 9

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Los-Pasos.h3856168.Hotel-Information)

![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/3b9c7ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/9e1d9d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/709e8c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/8a80f44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### El Convento Boutique Hotel

Historic Center, 1.5 km from Santa Ana

9.4/10

Exceptional

(782)

"El Convento is a beautiful and charming hotel with great service and views of the volcanoes; would definitely stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christine

CA $279

CA $362 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-El-Convento-Boutique-Hotel.h1836192.Hotel-Information)

![Breakfast, lunch, dinner served; international cuisine, garden views ](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/e487f2b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/9271a899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Multiple Beds, Non Smoking (Upgrade) | Private kitchen](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/93a5ace2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/d751d638.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clarion Suites Guatemala City

23.3 km from Santa Ana

9.0/10

Wonderful

(1003)

"Excellent hotel !! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sergio

CA $148

CA $181 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/16df8b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/44052a3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/a855c123.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/d07c12ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental Real Guatemala by IHG

23.2 km from Santa Ana

9.2/10

Wonderful

(1000)

"Clean room and amenities"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nubia

CA $251

CA $324 total

includes taxes & fees

Dec 6 - Dec 7

[](https://www.expedia.ca/Guatemala-City-Hotels-Real-InterContinental-Guatemala.h558105.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/b1a04679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/70585ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, 1 King Bed](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/5b5886bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/443e134d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Centric Guatemala City

23.3 km from Santa Ana

9.6/10

Exceptional

(763)

"Excelente Hotel "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Blanca

CA $197

CA $241 total

includes taxes & fees

Dec 6 - Dec 7

[](https://www.expedia.ca/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information)

![2 treatment rooms](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/111c1f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/861f04e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/fd2021bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/4114c275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Las Americas

22.3 km from Santa Ana

8.4/10

Very good

(1001)

"The breakfast is great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Darrol

CA $126

CA $153 total

includes taxes & fees

Nov 20 - Nov 21

[](https://www.expedia.ca/Guatemala-City-Hotels-Hotel-Las-Americas.h17403610.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/84429269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/2c82f338.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Quadruple Room](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/9a5ec6ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/3b89d44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Naif Boutique Hotel

Historic Center, 1.4 km from Santa Ana

8.8/10

Excellent

(359)

"Terrible"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eddie

CA $115

CA $141 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Naif-Boutique-Hotel-Gallery.h12847243.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/058db2db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/d66e2431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/abfb8ea4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/101420c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Posada de Don Rodrigo Antigua

Historic Center, 1.5 km from Santa Ana

9.4/10

Exceptional

(632)

"Lovely hotel, good food. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Lucy

CA $205

CA $284 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/0239c2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/8beeaba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite 203 | Bathroom](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/c0ec7452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/2e971ddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mestizo Cortijo

4.3 km from Santa Ana

9.0/10

Wonderful

(85)

"They just need to improve there breakfast "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Norma

CA $174

CA $212 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Ciudad-Vieja-Hotels-Mestizo-Cortijo.h103126773.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da5ce8e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor wedding](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/7bd53f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/cc2d383a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Porta Hotel Antigua

1.1 km from Santa Ana

9.4/10

Exceptional

(1000)

"Outstanding hotel and location, my family and I had a blast, super friendly staff, extremely clean rooms and amenities, easy transportation from hotel to parking or viceversa, the food is exceptional a bit pricey but worth every penny! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Frank

CA $229

CA $293 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/74000000/73580000/73570300/73570287/0af94433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room](https://images.trvl-media.com/lodging/74000000/73580000/73570300/73570287/efc76330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/74000000/73580000/73570300/73570287/8e3d1c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/74000000/73580000/73570300/73570287/8f358ec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villas Santander - Deluxe Stay

24.5 km from Santa Ana

7.6/10

Good

(201)

"Great stay staff was nice The only one thing is it’s not noise proof. You do hear everything. But other than that great place will go again !!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elias

CA $45

CA $55 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Guatemala-City-Hotels-Villas-Santander-Deluxe-Stay.h73570287.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/52a25915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/de4de24c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Triple Room, 3 Single Beds](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/f5243e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/93cd0a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### In & Out Hotel

20.9 km from Santa Ana

8.4/10

Very good

(789)

"Breakfast included "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chelsea

CA $74

CA $91 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Guatemala-City-Hotels-In-Out-Hotel.h16223612.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/112000000/111140000/111131100/111131046/1a3fcc86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111140000/111131100/111131046/b6928e06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, Courtyard View](https://images.trvl-media.com/lodging/112000000/111140000/111131100/111131046/3276d9cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111140000/111131100/111131046/23931444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Casa Carmina

1.2 km from Santa Ana

9.0/10

Wonderful

(186)

"Great place to stay the staff were very friendly and welcoming "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vanessa Sanchez

CA $90

CA $109 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Casa-Carmina.h111131046.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-21&endDate=2025-11-22&regionId=553248635975847775&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

-   Historic Center
-   Barrio de La Concepción

![](https://mediaim.expedia.com/destination/1/74ddc5a8bc392ba990ada31c1bf76007.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/bd4f4cf2ac6696e4d9dd7a1c5261170e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b494c5622ebb15c1dd7e91ce76ce75f2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/3d9e1f30df3a11ff4ad43007765de7e3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b2651b17b5e3f38b232fea61824aba4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911355684795535360)

![Historic Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:o%7EzwAthyhPXoK_%40%7Di%40ri%40a%40j%40fv%40yj%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=r_Zy9R--c8e6nlgWjV2_dDRw1Is=)

### Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911355684795535360)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911356092010033152)

![Barrio de La Concepción map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mqzwAlqwhPIwL%60E%7DHfFdBW%60SgKL&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Z_eq5PTC3hcK7WdhMP04Ad5umoE=)

### Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911356092010033152)

## Top Santa Ana Hotel Reviews

![Hotel Las Americas](//images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/111c1f7f_y.jpg)

### Hotel Las Americas

10/10 Excellent

"Front dest need to be a little more friendly and kinda smile more, remember they are the face of the hotel. House keeping the best part fast, clean, and friendly. "

[](https://expedia.ca/Guatemala-City-Hotels-Hotel-Las-Americas.h17403610.Hotel-Information)

![Hotel Biltmore Guatemala](//images.trvl-media.com/lodging/2000000/1400000/1397600/1397563/1b77a837_y.jpg)

### Hotel Biltmore Guatemala

10/10 Excellent

"My wife and I stayed for 2 nights at this hotel. The hotel and room where cleaned and perfect for the occasion. Free and in-garage safe parking was very convenient. The staff was friendly. Location was great since it was near malls ans restaurants. We enjoyed our stay."

[](https://expedia.ca/Guatemala-City-Hotels-Hotel-Biltmore-Guatemala.h1397563.Hotel-Information)

![Wyndham Garden Guatemala City](//images.trvl-media.com/lodging/1000000/30000/26600/26567/9a5888bf_y.jpg)

### Wyndham Garden Guatemala City

10/10 Excellent

"Very convenient with proximity to the airport. Standard amenities and clean. Friendly/helpful staff. Breakfast included was amazing! "

[](https://expedia.ca/Guatemala-City-Hotels-Wyndham-Garden-Guatemala-City.h26567.Hotel-Information)

![Hotel Casa Veranda](//images.trvl-media.com/lodging/2000000/1520000/1510700/1510614/aa4e2bf5_y.jpg)

### Hotel Casa Veranda

10/10 Excellent

"The hotel changed a bit, the rooms are still beautiful and comfortable. "

[](https://expedia.ca/Guatemala-City-Hotels-Hotel-Casa-Veranda.h1510614.Hotel-Information)

![Porta Hotel Antigua](//images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6_y.jpg)

### Porta Hotel Antigua

10/10 Excellent

"Nice service, good & clean rooms. Amazing garden with tropical flowers and trees. Beautiful!"

[](https://expedia.ca/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information)

![Barceló Guatemala City](//images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f_y.jpg)

### Barceló Guatemala City

10/10 Excellent

"Very good room and clean "

[](https://expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![Clarion Suites Guatemala City](//images.trvl-media.com/lodging/1000000/30000/27900/27811/e487f2b2_y.jpg)

### Clarion Suites Guatemala City

10/10 Excellent

"Clean room and friendly staff!"

[](https://expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information)

![Hotel Camino Real Antigua](//images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378_y.jpg)

### Hotel Camino Real Antigua

10/10 Excellent

"Wonderful as always "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information)

![Tikal Futura Hotel & Convention Center](//images.trvl-media.com/lodging/1000000/50000/48600/48502/11a701a2_y.jpg)

### Tikal Futura Hotel & Convention Center

10/10 Excellent

"Grat hotel"

[](https://expedia.ca/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information)

## Frequently asked questions

### What's it like in Santa Ana?

> Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.

### What's a favorite hotel to stay in Santa Ana?

> Based on Expedia customer reviews, [Casa Buho B&B](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information) is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking.

### How many hotels will I be able to find in Santa Ana?

> If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 18 hotels and other accommodations in Santa Ana.

### If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

> Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.

### What are the top things to see and do in Santa Ana?

> House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.