Title: Book the Best Amazonia LUXURY Hotels - Upscale Hotels in Amazonia, MO | Expedia.ca [Hotels in Amazonia](https://expedia.ca/Amazonia-Hotels.d3000349270.Travel-Guide-Hotels)[Vacation Rentals in Amazonia](https://expedia.ca/Amazonia-Vacation-Rentals.d3000349270.Travel-Guide-VacationRentals)[Amazonia Car Rentals](https://expedia.ca/Car-Rentals-In-Amazonia.d3000349270.Car-Rental-Guide)[Amazonia Vacation Packages](https://expedia.ca/Amazonia.d3000349270.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Amazonia, MO ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Amazonia Luxury Hotels Tonight [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=3000349270&startDate=2025-10-01&endDate=2025-10-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=3000349270&startDate=2025-10-02&endDate=2025-10-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000349270&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000349270&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Amazonia Luxury Hotels ## Top Amazonia Hotel Reviews ![Quality Suites St. Joseph](//images.trvl-media.com/lodging/1000000/130000/120700/120698/3416454f_y.jpg) ### Quality Suites St. Joseph 10/10 Excellent "Yes!!! Scrambled eggs, biscuits and gravy were hot and delicious!!! The suite was very spacious. Bathroom floor was dirty- had long black hair in the corners. The tub didn’t drain very fast. It could use a few updates. " [](https://expedia.ca/St-Joseph-Hotels-Quality-Suites-St-Joseph.h120698.Hotel-Information) ![Whiskey Mansion](//images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/81b46103_y.jpg) ### Whiskey Mansion 10/10 Excellent "The accomodations were excellent, breakfast was wonderful. 10/10 would stay again." [](https://expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ![Motel 6 Saint Joseph, MO](//images.trvl-media.com/lodging/1000000/50000/49600/49581/771cfdad_y.jpg) ### Motel 6 Saint Joseph, MO 8/10 Good "Room was surface clean at least. Towels were clean. Blanket on the bed had a cig burn in it. Shower was not really clean. What looked like possible blood on bathroom door. There is only the bed, tv, and table with one chair which the mini fridge is sitting on. No chairs to sit in. Had to lay or sit on bed. TV didnt work upon arrival, however they did replace it with a working one. Pool was drained and closed "for maintainance" but it looked like it hasnt been operable in sometime. It was in poor condition. Parking lot in bad shape, full of potholes." [](https://expedia.ca/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury getaway to Amazonia? > Amenities are an important consideration when you plan a vacation, so we make it easy to get what you need to make your stay special. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Amazonia has to offer. Amazonia has some interesting things to see and do including Missouri River, so you might want to take in the local sights during your visit. ### When can I expect good weather in Amazonia? > Planning for the weather is a good way to make your trip to Amazonia relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 33°F. Average annual precipitation for Amazonia is 44 inches. ### What's there to see and do in Amazonia? > Take in some sights and attractions while you're in Amazonia by visiting Missouri River, St. Jo Frontier Casino, and Glore Psychiatric Museum. 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