Title: Book the Best BUSINESS Hotels in Alachua in 2026 | Expedia.ca [Hotels in Alachua](https://expedia.ca/Alachua-Hotels.d5933.Travel-Guide-Hotels)[Vacation Rentals in Alachua](https://expedia.ca/Alachua-Vacation-Rentals.d5933.Travel-Guide-VacationRentals)[Alachua Car Rentals](https://expedia.ca/Car-Rentals-In-Alachua.d5933.Car-Rental-Guide)[Alachua Vacation Packages](https://expedia.ca/Alachua.d5933.Destination-Travel-Guides) ![Hay Bales and Farmland in Alachua County, Florida](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Alachua Business Hotels Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=5933&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=5933&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=5933&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=5933&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Alachua business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/e851cfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/a1c39a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/758be2b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds (Walk-In Shower)](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/578d088f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Alachua - Gainesville Area by IHG [](https://www.expedia.ca/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information) Alachua 9.4/10 Exceptional (1,000 reviews) "Staff and hotel were wonderful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $147 CA $166 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/1d4a6615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/847fac5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/2dd8879c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/68371972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Alachua I-75 [](https://www.expedia.ca/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) Alachua 9.4/10 Exceptional (484 reviews) "We visited family in the area and stayed here, hotel was clean, quiet, staff was great and room was so comfortable and spacious for our family of 5\. Will definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Libbi CA $142 CA $160 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/900000/898800/898728/3c5f8667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/900000/898800/898728/8f469985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/898800/898728/3f8c302d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/898800/898728/d20f6fd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Alachua - Gainesville Area [](https://www.expedia.ca/Gainesville-Hotels-Quality-Inn-I-75-At-Exit-399.h898728.Hotel-Information) Alachua 7.2/10 Good (1,003 reviews) "The staff were great and the room was clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamie CA $87 CA $98 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Gainesville-Hotels-Quality-Inn-I-75-At-Exit-399.h898728.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/7400/7326/a1a4d6c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/7400/7326/2221baa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/7400/7326/5dfe9f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/7400/7326/918d16cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alachua Inn [](https://www.expedia.ca/Gainesville-Hotels-Travelodge-By-Wyndham-Alachua.h7326.Hotel-Information) Alachua 5.8/10 (661 reviews) "Room was clean and staff were courteous. The place isn't in a good area and, the outside doesn't look the same as the picture, it is worse. Staff were outside smoking and no one was at the front desk. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shirl CA $84 CA $102 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Gainesville-Hotels-Travelodge-By-Wyndham-Alachua.h7326.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/2f0849f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4d594d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4e0d3764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOM Hotel Gainesville, SureStay Collection by Best Western [](https://www.expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) Gainesville 8.4/10 Very good (1,812 reviews) "Awesome place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aristeo CA $117 CA $131 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/95cd6e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/fd018b8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/d62bb37b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/88194727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Gainesville near University [](https://www.expedia.ca/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) Gainesville 9.2/10 Wonderful (1,220 reviews) "Awesome stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maricarmen CA $128 CA $144 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/e93e0d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/57b6c63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Gainesville [](https://www.expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) Gainesville 9.6/10 Exceptional (1,366 reviews) "Great place to stay. Would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leo CA $143 CA $161 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/087f9766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only)](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/5e1b0ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/51675133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/13f62121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Starke [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information) Starke 8.6/10 Excellent (673 reviews) "Quiet place, no issues checking in Or out." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia CA $135 CA $150 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/9c03edaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/w2878h1920x0y0-ae7e9910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/f5784012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Gainesville, FL [](https://www.expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) Gainesville 9.2/10 Wonderful (1,663 reviews) "The room was great the staff was so nice. I would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terri CA $121 CA $136 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/e8bf5c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/d8c6de93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/f7f29b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites University/Shands [](https://www.expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) Gainesville 8.8/10 Excellent (1,095 reviews) "Clean room and nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $109 CA $131 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=5933&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Alachua Hotel Reviews ![Drury Inn & Suites Gainesville](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773_y.jpg) ### Drury Inn & Suites Gainesville 10/10 Excellent "The employees were all extremely nice and friendly! Wow! The snack spread was amazing! " [](https://expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg) ### Sleep Inn & Suites University/Shands 10/10 Excellent "Everything was spotless. Beds and pillows were very comfortable. Will stay there again. " [](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Country Inn & Suites by Radisson, Gainesville, FL](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/8584a629_y.jpg) ### Country Inn & Suites by Radisson, Gainesville, FL 10/10 Excellent "Loved very clean" [](https://expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg) ### Comfort Inn University 10/10 Excellent "Clean room, quiet, nice breakfast" [](https://expedia.ca/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Quality Inn Alachua - Gainesville Area](https://images.trvl-media.com/lodging/1000000/900000/898800/898728/3dbf950e_y.jpg) ### Quality Inn Alachua - Gainesville Area 10/10 Excellent "The staff was wonderful and the room was very welcoming. " [](https://expedia.ca/Gainesville-Hotels-Quality-Inn-I-75-At-Exit-399.h898728.Hotel-Information) ![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/07c3ba53_y.jpg) ### HOM Hotel Gainesville, SureStay Collection by Best Western 10/10 Excellent "Very nice and clean " [](https://expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Best Western Gateway Grand](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/9a241e09_y.jpg) ### Best Western Gateway Grand 10/10 Excellent "Friendly staff, clean hotel." [](https://expedia.ca/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information) ![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg) ### DoubleTree by Hilton Gainesville 10/10 Excellent "👍" [](https://expedia.ca/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Alachua cost? ### What are the best business-friendly hotels in Alachua? ### How many business-friendly hotels are there in Alachua? ### Are there any family-friendly hotels in Alachua that are also business friendly? ### Why book your business-friendly hotel in Alachua with Expedia? ### How can I find cheap business-friendly hotels in Alachua? ### What is there to do in Alachua near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Hotels with a Pool in Amelia Island ](https://www.expedia.ca/Amelia-Island-Hotels-Hotel-With-Pool.0-0-d10814-tHotelwithPool.Travel-Guide-Filter-Hotels) - 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