St. Peter's Square with the obelisk, colonnades, and Bernini's sculpture of a man with a scythe.

Best 5 Star Hotels in Vatican City CA $311

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Check availability on Vatican City 5 Star Hotels

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Oct 3 - Oct 4
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Oct 16 - Oct 18

Our top choices for Vatican City 5-star hotels

A modern gym with various exercise equipment, a large mirror, and a television.
Room
Room
Room

1. Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
Rome City Centre
United States
Sharon
CA $913
CA $1,036 total
includes taxes & fees
Nov 3 - Nov 4
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
A multi-story hotel with a grand entrance, multiple balconies, and a well-lit facade.
A rooftop lounge with modern seating, ambient lighting, and a city view.
A rooftop bar with a glass ceiling, seating, and a bar stocked with bottles.
A spacious lobby with a central seating area, a chandelier, and a large plant.

2. InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG
Rome City Centre
Canada
Shaza
CA $770
CA $879 total
includes taxes & fees
Nov 2 - Nov 3
InterContinental Rome Ambasciatori Palace by IHG
A hotel entrance with a covered entrance, a cobblestone pathway, and potted plants.
A family on a balcony overlooking a cityscape with historic buildings and a dome in the distance.
A grand lobby with a checkered floor, elegant furniture, and a chandelier.
A grand lobby with a marble staircase, ornate chandeliers, and classical statues.

3. Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World
Rome City Centre
United States
Robert
CA $681
CA $781 total
includes taxes & fees
Nov 2 - Nov 3
Baglioni Hotel Regina - The Leading Hotels of the World
A luxurious indoor pool area with a circular pool, large windows, and a view of the cityscape.
A grand lobby with checkered flooring, ornate chandeliers, and classic furniture.
A luxurious lobby with a grand ceiling, elegant furniture, and large windows.
A modern interior with a bar area, seating arrangements, and large windows offering natural light and views.

4. The Westin Excelsior, Rome

The Westin Excelsior, Rome
Rome City Centre
United States
Christopher
CA $614
CA $707 total
includes taxes & fees
Nov 3 - Nov 4
The Westin Excelsior, Rome
A hotel with ivy-covered walls, a prominent tower, and a well-lit entrance.
A modern hotel room with a large bed, a television, a small table with a plant, and a large tapestry on the wall.
A luxurious hotel room with a large bed, a sitting area with a chessboard, a view of a building through a window, and a painting on the wall.
A hotel room with a large window, a red armchair, a table with a book, and a television on the wall.

5. Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux
Rome City Centre
United States
Franz
CA $617
CA $711 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Raphaël – Relais & Châteaux
A hotel entrance with a cobblestone pathway, large potted plants, and a sign indicating room number 36.
A modern interior with seating areas, decorative plants, and a red carpet.
A neatly made bed with white linens, two glasses of white wine, and a tray with fruit and a small bottle on a wooden tray.
A bar area with a wooden bar counter, blue bar stools, and a well-stocked liquor shelf.

6. Umiltà 36 - Preferred Hotels & Resorts

Umiltà 36 - Preferred Hotels & Resorts
Rome City Centre
Canada
Ghassan
CA $945
CA $1,072 total
includes taxes & fees
Oct 31 - Nov 1
Umiltà 36 - Preferred Hotels & Resorts
A rooftop terrace with a table set for dining, featuring a lamp, wine glass, and plates of food. In the background, there is a large classical building with statues on top.
A modern hotel room with a view of a historic building, a dining area with a table and chairs, and potted plants.
A breakfast buffet with various food items, a coffee machine, and a decorative orchid plant.
A modern lobby with a sofa, chairs, a coffee table, and potted plants.

7. Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica
Rome City Centre
United States
Thomas
CA $694
CA $796 total
includes taxes & fees
Oct 26 - Oct 27
Radisson Collection Hotel, Roma Antica
A luxurious dining area with ornate chandeliers, elegant table settings, and a scenic view of the cityscape at dusk.
A buffet setup with various food items and a vase of white flowers.
A grand lobby with marble columns, a central seating area, and a decorative mirror.
A grand staircase with black steps and gold accents, leading to a high-ceilinged room with a chandelier.

8. Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World
Rome City Centre
United States
jorgelina
CA $856
CA $974 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Splendide Royal - The Leading Hotels of the World
The entrance of Grand Hotel Palace with a grand arched doorway, a chandelier, and a potted plant.
A grand hotel entrance with a large archway, a flag, and outdoor seating with umbrellas.
A historic building with a grand entrance, multiple balconies, and outdoor seating areas.
A luxurious room with a bar area, red chairs, a large chandelier, and a painting on the wall.

9. Grand Hotel Palace Rome

Grand Hotel Palace Rome
Rome City Centre
United States
Babak
CA $638
CA $734 total
includes taxes & fees
Nov 2 - Nov 3
Grand Hotel Palace Rome
A spacious lobby with a reflective floor, a central seating area, and a decorative wall with a floral pattern.
A bar area with shelves of liquor bottles and a curved wall design.
An outdoor bar area with seating and a bar counter, featuring umbrellas and ambient lighting.
The exterior of Nobu Hotel Via Veneto with a classic architectural style, featuring a marquee sign, arched entrances, and potted plants at the doors.

10. Nobu Hotel Roma

Nobu Hotel Roma
Rome City Centre
United States
LARRY
CA $818
CA $900 total
includes taxes & fees
Nov 3 - Nov 4
Nobu Hotel Roma
A grand hotel lobby with a large chandelier, seating areas, and a checkered floor pattern.
A grand banquet hall with multiple round tables, ornate chandeliers, and a ceiling fresco.
View from property
An outdoor dining area with tables and chairs, hanging lanterns, and greenery.

11. The St. Regis Rome

The St. Regis Rome
Rome City Centre
United States
Dennis
CA $1,500
CA $1,682 total
includes taxes & fees
Oct 18 - Oct 19
The St. Regis Rome
An outdoor terrace with tables and chairs, a large umbrella, and a city view at sunset.
A modern room with a glass partition, a chair, a small table, and potted plants.
A hotel room with two beds, a large painting on the wall, a modern lamp, and a view of the city through the window.
A hotel room with two beds, a large window with a view of buildings, a desk with a lamp, and a small window on the right.

12. U-Visionary Roma Hotel

U-Visionary Roma Hotel
Rome City Centre
United Kingdom
Nisha
CA $536
CA $622 total
includes taxes & fees
Nov 1 - Nov 2
U-Visionary Roma Hotel
A balcony with outdoor furniture, a table with glasses, and a book.
A luxurious lobby with a checkered floor, ornate furniture, and a large mirror with an elaborate frame.
A modern bathroom with a bathtub, a shower area, and a vanity with a mirror.
A hotel room with a large bed, a vanity with a mirror, a chandelier, and a view of the bathroom.

13. Hotel d'Inghilterra Roma - Starhotels Collezione

Hotel d'Inghilterra Roma - Starhotels Collezione
Rome City Centre
United States
Renee
CA $983
CA $1,114 total
includes taxes & fees
Nov 2 - Nov 3
Hotel d'Inghilterra Roma - Starhotels Collezione
An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.
A modern interior with a glass railing and a marble floor.
A large hotel with multiple floors, a well-maintained lawn, and outdoor seating areas.
A spacious lobby with a marble floor, glass elevator, and a view of the cityscape through large windows.

14. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
Rome City Centre
Mexico
LEONARDO
CA $538
CA $624 total
includes taxes & fees
Nov 1 - Nov 2
NH Collection Roma Palazzo Cinquecento
A grand hall with a long table set for a banquet, ornate chandeliers, and classical wall paintings.
Room
A grand staircase with a statue at the top, flanked by ornate balustrades and a chandelier.
A room with a central seating area, framed pictures on the walls, and busts on the right.

15. Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World
Rome City Centre
Canada
Anais
CA $896
CA $1,017 total
includes taxes & fees
Nov 2 - Nov 3
Palazzo Roma - The Leading Hotels of the World
A dining table set with plates, glasses, and a vase of flowers on a balcony with red chairs, overlooking a historic building with statues.
A hotel room with a large bed, a TV, a desk with a chair, and large windows with city views.
A building entrance with a sign reading 'NH COLLECTION FOR IMPERIAL,' potted plants on either side, and a staircase leading inside.
A hotel dining area with marble walls, red chairs, and tables set for dining.

16. NH Collection Roma Fori Imperiali

NH Collection Roma Fori Imperiali
Rome City Centre
United States
Shawn
CA $892
CA $1,014 total
includes taxes & fees
Oct 31 - Nov 1
NH Collection Roma Fori Imperiali
A spacious lobby with a patterned carpet, columns, and potted plants.
A bar area with a statue, bar stools, and a patterned floor.
A dining area with a round table, two chairs, and a view of buildings through a window with curtains.
A traditional room with a high ceiling, wooden lattice partitions, a green sofa, a small table, and a bench.

17. Orient Express La Minerva

Orient Express La Minerva
Rome City Centre
France
Brahim
CA $1,797
CA $2,009 total
includes taxes & fees
Nov 1 - Nov 2
Orient Express La Minerva
An outdoor seating area with a round table and chairs, surrounded by potted plants.
A grand marble staircase with multiple landings and ornate railings.
A modern bar area with a marble countertop, multiple bar stools, and a variety of potted plants.
A spacious lobby with multiple seating areas, large potted plants, and a central bar area.

18. Six Senses Rome

Six Senses Rome
Rome City Centre
United States
Kurt
CA $1,568
CA $1,757 total
includes taxes & fees
Nov 1 - Nov 2
Six Senses Rome
A grand entrance with a glass door, a balcony with ornate railings, and a number '26' on the wall.
A narrow street with buildings on either side, featuring balconies and windows with shutters.
A luxurious bar area with marble flooring, gold bar counters, and a seating area with a blue sofa and round ottomans.
A modern kitchen with a marble countertop, green cabinets, and a central island with bar stools.

19. W Rome

W Rome
Rome City Centre
United States
Katherine
CA $817
CA $930 total
includes taxes & fees
Oct 25 - Oct 26
W Rome
A building facade with a central entrance, flanked by two windows with curtains, and a balcony with greenery.
An outdoor seating area with tables and chairs, surrounded by large potted plants and a building with balconies in the background.
A corridor with a wooden floor, flanked by vertical metal railings and potted plants, leading to a door with a circular emblem.
A bar area with wooden chairs and sofas, a wall of illuminated liquor bottles, and greenery overhead.

20. The Rome EDITION

The Rome EDITION
Rome City Centre
United Kingdom
Miss Vishali
CA $982
CA $1,112 total
includes taxes & fees
Nov 3 - Nov 4
The Rome EDITION
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Vatican City.
Hotel Delle Nazioni

Hotel Delle Nazioni

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CA $408
CA $473 total
Oct 6 - Oct 7
includes taxes & fees
9.4/10 Exceptional! (1,003 reviews)
Hotel Delle Nazioni
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

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CA $261
CA $311 total
Nov 2 - Nov 3
includes taxes & fees
Bettoja Hotel Mediterraneo
Marcella Royal Hotel - Rooftop Garden

Marcella Royal Hotel - Rooftop Garden

Via Flavia 106 Rome RM
CA $363
CA $423 total
Oct 25 - Oct 26
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
Marcella Royal Hotel - Rooftop Garden
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Learn more about Vatican City

Marvel at Michelangelo's masterpiece ceiling in the Sistine Chapel before climbing St. Peter's Basilica dome for panoramic views. Reserve tickets for the Vatican Museums well in advance to explore one of the world's greatest art collections without the longest lines.

See all hotels in Vatican City
St. Peter's Square with the obelisk, colonnades, and Bernini's sculpture of a man with a scythe.

Top Vatican City Hotel Reviews

Find out more about Vatican City

Five Star Hotels in Vatican City

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Vatican City so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Vatican City and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Vatican City

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Vatican City

The results are in, and Vatican City 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Vatican City! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Vatican City today and settle down in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Vatican City?
Prepare for 5-star indulgence at Villa Agrippina Gran Meliá - The Leading Hotels of the World, Hotel Indigo Rome - St. George, an IHG Hotel or DOM Hotel. These are some of the top-rated retreats in Vatican City according to Expedia customer reviews. Book one and enjoy a taste of the high life!
How much does it cost to stay in a 5-star hotel in Vatican City?
How much you pay for a 5-star hotel in Vatican City can vary depending on when you decide to travel and how long you plan to stay, among several factors. Use our price per night filter and other search tools to land the best rate on a luxurious getaway.
  • Search for the lowest price per night from CA $311
What makes a hotel 5 stars in Vatican City?
In Vatican City, a hotel must provide a certain level of upscale amenities to be designated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may even offer thoughtful touches such as a welcome gift.

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