Title: 5 Stars Hotels in South San Francisco, San Francisco from CA $218 - Find Cheap South San Francisco Hotels With 5 Stars | Expedia.ca

[South San Francisco Travel Guide](https://expedia.ca/South-San-Francisco.dx6773)[Hotels in South San Francisco](https://expedia.ca/South-San-Francisco-Hotels.d6773.Travel-Guide-Hotels)[Vacation Rentals in South San Francisco](https://expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals)[Flights to South San Francisco](https://expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)[Things to do in South San Francisco](https://expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)[South San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide)[South San Francisco Vacation Packages](https://expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides)

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Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

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## Check availability on South San Francisco 5 Star Hotels

Tonight

[Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2026-04-08&endDate=2026-04-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 9 - Apr 10](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2026-04-09&endDate=2026-04-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2026-04-17&endDate=2026-04-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for South San Francisco 5-star hotels

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fairmont Legacy Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/aa9ce76d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6a7a9dd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; Asian cuisine](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/908b91b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairmont San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information)

Downtown San Francisco

9.0/10

Wonderful

(1,505 reviews)

"Great staff; nice restaurants. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Robert

CA $343

CA $469 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/e72fe89a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/ad005a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/189643db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palace Hotel, a Luxury Collection Hotel, San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information)

Downtown San Francisco

9.2/10

Wonderful

(1,003 reviews)

"Wonderful stay! We loved it!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sara

CA $385

CA $518 total

includes taxes & fees

Apr 25 - Apr 26

[](https://www.expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/4ff57257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Union Square Deluxe King Bed | City view](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/e55a857c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/355c4c16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom (Campton)](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/0d62a8a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Taj Campton Place

[](https://www.expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information)

Union Square

9.2/10

Wonderful

(1,000 reviews)

"The Taj Campton is a welcoming place to stay and we have become repeat visitors. All the things that matter are met: cleanliness, comfort, thoughtfulness, location and friendliness. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $271

CA $367 total

includes taxes & fees

May 10 - May 11

[](https://www.expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/41a2cb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/91a3ba7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/90ac212c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/54bc54cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel San Francisco at Embarcadero

[](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco-At-Embarcadero.h6505.Hotel-Information)

Downtown San Francisco

9.6/10

Exceptional

(1,005 reviews)

"Very friendly staff and overall had a great visit"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

CA $632

CA $744 total

includes taxes & fees

May 9 - May 10

[](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco-At-Embarcadero.h6505.Hotel-Information)

![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/60488ea7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/10cefca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/5000cbe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/2335e7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 1 Hotel San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-1-Hotel-San-Francisco.h1138217.Hotel-Information)

Downtown San Francisco

9.2/10

Wonderful

(528 reviews)

"Great staff & very clean facility "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ARMANDO

CA $513

CA $682 total

includes taxes & fees

May 2 - May 3

[](https://www.expedia.ca/San-Francisco-Hotels-1-Hotel-San-Francisco.h1138217.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/bff475ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![LED TV, DVD player, iPod dock, first-run movies](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/7040d302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/ab6ff173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/0cd41feb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco.h791769.Hotel-Information)

Downtown San Francisco

9.4/10

Exceptional

(1,000 reviews)

" Excellent rooms and staff, terrific food, great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roberta

CA $658

CA $774 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco.h791769.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/ba76b95f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/76bdc90c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![47-inch flat-screen TV with digital channels, Smart TV, table tennis](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/fb1bec56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/b01c94c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Claremont Resort & Club

[](https://www.expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information)

Claremont Hills

9.0/10

Wonderful

(1,011 reviews)

"Great stay and property"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heather

CA $469

CA $624 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/e3b2f195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/d50915e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/acfbf8fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/5b42d596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Ritz-Carlton, San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-The-Ritz-Carlton.h22148.Hotel-Information)

Downtown San Francisco

9.4/10

Exceptional

(1,002 reviews)

"Absolutely amazing hotel and service "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Oksana

CA $470

CA $620 total

includes taxes & fees

Apr 24 - Apr 25

[](https://www.expedia.ca/San-Francisco-Hotels-The-Ritz-Carlton.h22148.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/a5681857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/w4000h2662x0y0-41a38e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Corner](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/29f2f698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/w4000h2662x0y0-fc84c036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The St. Regis San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-The-St-Regis-San-Francisco.h1321986.Hotel-Information)

Downtown San Francisco

9.4/10

Exceptional

(717 reviews)

"The hotel staff was so welcoming and took extra care of our two children by bringing surprise cookies and milk to the room, kid size spa robes and slippers and gifts upon checkout. The food at Astra was delicious and the indoor pool was so much fun. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Margeaux

CA $522

CA $678 total

includes taxes & fees

May 1 - May 2

[](https://www.expedia.ca/San-Francisco-Hotels-The-St-Regis-San-Francisco.h1321986.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/6ad77b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/39564830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Banquet hall](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/3a6d22ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/505d1efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Ritz-Carlton, Half Moon Bay

[](https://www.expedia.ca/Half-Moon-Bay-Hotels-The-Ritz-Carlton.h602927.Hotel-Information)

Ocean Colony

9.0/10

Wonderful

(662 reviews)

"This was an anniversary trip, and the staff made our stay so special!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heather

CA $1,120

CA $1,415 total

includes taxes & fees

May 10 - May 11

[](https://www.expedia.ca/Half-Moon-Bay-Hotels-The-Ritz-Carlton.h602927.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/b57fb1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed | Living area](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/699461f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/6acb5832.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/266312ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel Silicon Valley at East Palo Alto

[](https://www.expedia.ca/Palo-Alto-Hotels-Four-Seasons-Hotel-Silicon-Valley-At-East-Palo-Alto.h1334199.Hotel-Information)

East Palo Alto

9.4/10

Exceptional

(678 reviews)

"wonderful staff, ambience was spot on, we had an overnight stay and all went smooth from start to finish...."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

CA $648

CA $737 total

includes taxes & fees

Apr 24 - Apr 25

[](https://www.expedia.ca/Palo-Alto-Hotels-Four-Seasons-Hotel-Silicon-Valley-At-East-Palo-Alto.h1334199.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/4a2b8bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; local cuisine](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/8109caa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/0ae5285d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/1f76286f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rosewood Sand Hill

[](https://www.expedia.ca/Menlo-Park-Hotels-Rosewood-Sand-Hill.h2443731.Hotel-Information)

Menlo Park

9.4/10

Exceptional

(285 reviews)

"Quite and nice view "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mei

CA $1,225

CA $1,521 total

includes taxes & fees

Apr 18 - Apr 19

[](https://www.expedia.ca/Menlo-Park-Hotels-Rosewood-Sand-Hill.h2443731.Hotel-Information)

![Breakfast, lunch, dinner served; Japanese cuisine, alfresco dining ](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/w3000h1888x0y1-de3fb894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/5b484b69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deep soaking bathtub](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/8a9c2f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/e3f4a552.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nobu Hotel Palo Alto

[](https://www.expedia.ca/Palo-Alto-Hotels-Nobu-Hotel-Palo-Alto.h5890380.Hotel-Information)

University South

9.2/10

Wonderful

(443 reviews)

"Beautiful hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dianne

CA $634

CA $734 total

includes taxes & fees

May 9 - May 10

[](https://www.expedia.ca/Palo-Alto-Hotels-Nobu-Hotel-Palo-Alto.h5890380.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/35b03efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bicycling](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/4f9a25c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/c46c4772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/be4033e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Drisco

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Drisco.h74183.Hotel-Information)

Pacific Heights

9.8/10

Exceptional

(460 reviews)

"Great hotel and would highly recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Oliver

CA $859

CA $999 total

includes taxes & fees

Apr 27 - Apr 28

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Drisco.h74183.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/9ae8226d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/6f41305b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/9a41a095.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/3fbb1d83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairmont Heritage Place, Ghirardelli Square

[](https://www.expedia.ca/San-Francisco-Hotels-Fairmont-Heritage-Place.h1853240.Hotel-Information)

Fisherman's Wharf

9.4/10

Exceptional

(395 reviews)

"Wonderful place, I highly recommend staying here!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Teresa

CA $1,281

CA $1,505 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/San-Francisco-Hotels-Fairmont-Heritage-Place.h1853240.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/900/864/25ea6e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/864/ae41d781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Concierge desk](https://images.trvl-media.com/lodging/1000000/10000/900/864/167bd1f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/10000/900/864/8b2202a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  The Huntington Hotel

[](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information)

Downtown San Francisco

9.6/10

Exceptional

(4 reviews)

"Perfect location, perfect staff. Incredible experience. Get facial if you visit the spa!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chas

CA $857

CA $1,082 total

includes taxes & fees

Apr 10 - Apr 11

[](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/a415df7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/fb8da040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/e534761f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/66b6828b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Neighbourgood Sutter Mansion

[](https://www.expedia.ca/San-Francisco-Hotels-Mansion-On-Sutter.h7064385.Hotel-Information)

Western Addition

9.4/10

Exceptional

(237 reviews)

"Friendly staff, early 1900s decor and architecture."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Louis

CA $432

CA $564 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/San-Francisco-Hotels-Mansion-On-Sutter.h7064385.Hotel-Information)

![Deluxe House | Living room](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/3d63aff5_edited_fe52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe House | Balcony](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/f0f8fb7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe House | Private kitchen](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/c333cea6_edited_6ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe House](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/64feb916_edited_c3a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dimond Abode Vacation Rental

[](https://www.expedia.ca/Oakland-Hotels-Dimond-Abode-Vacation-Rental.h111467039.Hotel-Information)

Dimond

10/10

Exceptional

(1 review)

"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Camille

[](https://www.expedia.ca/Oakland-Hotels-Dimond-Abode-Vacation-Rental.h111467039.Hotel-Information)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/bb2d6232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/cdc429e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/w4322h2866x6y0-3800e1b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/7b60570a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dimond Abode Vacation Rental 3428

[](https://www.expedia.ca/Oakland-Hotels-Dimond-Abode-3428.h90324275.Hotel-Information)

Dimond

9.6/10

Exceptional

(7 reviews)

"Cleanliness, amenities, staff. It was a really great stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Phyllis

[](https://www.expedia.ca/Oakland-Hotels-Dimond-Abode-3428.h90324275.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South San Francisco.

![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA

CA $192

CA $284 total

Apr 12 - Apr 13

includes taxes & fees

9/10 Wonderful! (7,376 reviews)

[](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### DoubleTree by Hilton Hotel Berkeley Marina

200 Marina Blvd Berkeley CA

CA $189

CA $218 total

Apr 19 - Apr 20

includes taxes & fees

8.2/10 Very Good! (4,443 reviews)

[](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information)

![Grand Hyatt at SFO](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/e6f59e08_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Grand Hyatt at SFO

55 S McDonnell Rd San Francisco CA

CA $428

CA $478 total

Apr 10 - Apr 11

includes taxes & fees

9.8/10 Exceptional! (1,536 reviews)

[](https://expedia.ca/San-Francisco-Hotels-Grand-Hyatt-At-SFO.h33462010.Hotel-Information)

Still don't see what you're looking for?

[See all properties in South San Francisco.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&regionId=6773&star=50)

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[Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&regionId=6773&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&regionId=6773&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&regionId=6773&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&regionId=6773&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&regionId=6773&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about South San Francisco

Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Candies factory.

[See all hotels in South San Francisco](https://www.expedia.ca/Hotel-Search?startDate=2026-04-23&endDate=2026-04-24&adults=2&regionId=6773)

![](https://images.trvl-media.com/place/6773/149d3826-ba90-46a7-bd10-00098a5921a1.jpg?impolicy=fcrop&w=300&h=400&p=1&q=high)

Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

## Top South San Francisco Hotel Reviews

## Find out more about South San Francisco

## Five Star Hotels in South San Francisco

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made South San Francisco so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in South San Francisco and get ready to be pampered like never before.

#### Get a Great Deal on 5-Star Hotels in South San Francisco

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. 

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

#### Make Your Escape to South San Francisco

The results are in, and South San Francisco 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in South San Francisco! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in South San Francisco today and settle down in the lap of luxury tomorrow.

## Frequently asked questions

### What are the best 5-star hotels in South San Francisco?

### How much does it cost to stay in a 5-star hotel in South San Francisco?

> - Search for the lowest price per night from CA $218

### What makes a hotel 5 stars in South San Francisco?

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- [Aparthotels in South San Francisco Station ](https://www.expedia.ca/South-San-Francisco-Station-Apart-Hotels.d6173603-aaApartHotels.Travel-Guide-Accommodation)
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- [Beach Hotel Hotels in Sunshine Gardens ](https://www.expedia.ca/Sunshine-Gardens-San-Francisco-Hotels-Beach-Hotel.0-n553248635976470279-0-tBeachHotel.Travel-Guide-Filter-Hotels)
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- [Flights to San Bruno ](https://www.expedia.ca/Cheap-Flights-To-San-Bruno.d6633.Travel-Guide-Flights)
- [Flights to San Francisco ](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)
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- [Visit Paradise Valley ](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811)

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- [Things to do in San Bruno ](https://www.expedia.ca/Things-To-Do-In-San-Bruno.d6633.Travel-Guide-Activities)

- [Book 5 Star Hotels in South San Francisco on Expedia.com ](https://www.expedia.com/5Star-South-San-Francisco-Hotels.s50-0-d6773.Travel-Guide-Filter-Hotels)