Title: 5 Stars Hotels in South San Francisco, San Francisco from CA $211 - Find Cheap South San Francisco Hotels With 5 Stars | Expedia.ca [South San Francisco Travel Guide](https://expedia.ca/South-San-Francisco.dx6773)[Hotels in South San Francisco](https://expedia.ca/South-San-Francisco-Hotels.d6773.Travel-Guide-Hotels)[Vacation Rentals in South San Francisco](https://expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals)[Flights to South San Francisco](https://expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)[Things to do in South San Francisco](https://expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)[South San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide)[South San Francisco Vacation Packages](https://expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/edf3b75ded644f2805fb6e835771cc8f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in South San Francisco, San Francisco from CA $211 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South San Francisco 5 Star Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2025-10-15&endDate=2025-10-16&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2025-10-16&endDate=2025-10-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6773&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South San Francisco 5 Star Hotels ![3 outdoor pools, open 6:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/d997dca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/ba76b95f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/0206b740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Bay View, Tower](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/3adb309a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Claremont Resort & Club Claremont Hills 8.8/10 Excellent (1019) "Absolutely love it here!" CA $391 CA $534 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/48a8da0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/94d8cb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/94a155f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairmont San Francisco Downtown San Francisco 9.0/10 Wonderful (1406) "Beautiful property and grear staff" CA $322 CA $437 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d044cc49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d5b628f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/67a43361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/111bcf12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Taj Campton Place Union Square 9.2/10 Wonderful (1013) "I would stay here again." CA $250 CA $343 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/41a2cb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Terrace (Golden Gate)](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/e2b1deb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/91a3ba7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/10000/6600/6505/54bc54cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel San Francisco at Embarcadero Downtown San Francisco 9.6/10 Exceptional (1006) "We were able to check in early. Staff were amazing. Hotel is gorgeous. Had champagne for our anniversary Would definitely stay here again " CA $626 CA $736 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco-At-Embarcadero.h6505.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/09d35b14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/189643db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/952f2e20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Hotel, a Luxury Collection Hotel, San Francisco Downtown San Francisco 9.2/10 Wonderful (1005) "Stayed at the Palace a number of times in the past.. One of the best hotels when on business travel to SF. Great spacious lobby to take meetings / work out of." CA $391 CA $460 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/bff475ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/ab6ff173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/4df53291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/fba34236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel San Francisco Downtown San Francisco 9.4/10 Exceptional (1006) "Really nice staff and we had a wonderful stays " CA $583 CA $686 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco.h791769.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/5b42d596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Frette Italian sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/9c478019.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/dadccd3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/1000000/30000/22200/22148/4f41225f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, San Francisco Downtown San Francisco 9.4/10 Exceptional (1009) "Great staff and rooms, restaurant and bar options and service were top quality." CA $483 CA $637 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/San-Francisco-Hotels-The-Ritz-Carlton.h22148.Hotel-Information) ![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/60488ea7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/24d494d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Studio Suite | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/0d31bb88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/dc2c64db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 Hotel San Francisco Downtown San Francisco 9.2/10 Wonderful (462) "Great location and property" CA $490 CA $651 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-1-Hotel-San-Francisco.h1138217.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/754cc790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite (Deluxe)](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/9db6261e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/ea1c64f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite](https://images.trvl-media.com/lodging/2000000/1340000/1334200/1334199/bc93db64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel Silicon Valley at East Palo Alto East Palo Alto 9.4/10 Exceptional (658) "Wonderful stay " CA $674 CA $766 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Palo-Alto-Hotels-Four-Seasons-Hotel-Silicon-Valley-At-East-Palo-Alto.h1334199.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/9bc64d44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/0ae5285d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; local cuisine](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/8109caa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite (Rosewood)](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443731/7a9d26ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rosewood Sand Hill Menlo Park 9.4/10 Exceptional (269) "Good people great service " CA $1,245 CA $1,526 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Menlo-Park-Hotels-Rosewood-Sand-Hill.h2443731.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Corner](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/29f2f698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/0fbc7ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/6f2f905e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/w4000h2662x0y0-fc84c036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The St. Regis San Francisco Downtown San Francisco 9.4/10 Exceptional (684) "Had a great stay " CA $612 CA $785 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-The-St-Regis-San-Francisco.h1321986.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/w4000h2663x0y0-17193ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room, 1 Bedroom | Beach/ocean view](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/1ebd9440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/191e7c87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Club Room, Balcony, Ocean View](https://images.trvl-media.com/lodging/1000000/610000/603000/602927/6f98b61b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, Half Moon Bay Half Moon Bay 9.0/10 Wonderful (637) "The staff throughout the resort were extremely friendly and helpful." CA $1,164 CA $1,459 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Half-Moon-Bay-Hotels-The-Ritz-Carlton.h602927.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/1c9e89eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/ebe791fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/820475b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Japanese cuisine, alfresco dining ](https://images.trvl-media.com/lodging/6000000/5900000/5890400/5890380/fc20744f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu Hotel Palo Alto University South 9.2/10 Wonderful (424) "Excellent property and stay " CA $559 CA $647 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Palo-Alto-Hotels-Nobu-Hotel-Palo-Alto.h5890380.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/35b03efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/be4033e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/50bb3f17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City View Guestroom | City view](https://images.trvl-media.com/lodging/1000000/80000/74200/74183/caeeeb03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Drisco Pacific Heights 9.8/10 Exceptional (449) "Very good hotel area, room size , amenities , service " CA $795 CA $925 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Drisco.h74183.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/193b84d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/fb8da040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/3ae08081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7070000/7064400/7064385/26a8f324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Neighbourgood Sutter Mansion Western Addition 9.4/10 Exceptional (223) "Beautifully restored property with very tasteful furnishings. Staff very helpful and polite. A real pleasure to stay in. Top quality stay." CA $608 CA $781 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/San-Francisco-Hotels-Mansion-On-Sutter.h7064385.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/9ae8226d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/3fbb1d83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/6f41305b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853240/e6f1bfe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairmont Heritage Place, Ghirardelli Square Fisherman's Wharf 9.4/10 Exceptional (383) "Great staff, clean, excellent location, spacious rooms" CA $1,439 CA $1,691 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/San-Francisco-Hotels-Fairmont-Heritage-Place.h1853240.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/w4327h2866x6y3-9b9c25a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/6e060fa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/534d119c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/91000000/90330000/90324300/90324275/9a697550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dimond Abode Vacation Rental 3428 Dimond 9.6/10 Exceptional (5) "Great place, great customer service!" [](https://www.expedia.ca/Oakland-Hotels-Dimond-Abode-3428.h90324275.Hotel-Information) ![Deluxe House | Balcony](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/f0f8fb7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe House | Living room](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/8267bbc3_edited_53c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe House](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/9ec933cb_edited_b2a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111470000/111467100/111467039/19449633_edited_3b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dimond Abode Vacation Rental Dimond 10/10 Exceptional (1) "The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+" [](https://www.expedia.ca/Oakland-Hotels-Dimond-Abode-Vacation-Rental.h111467039.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-South-San-Francisco-Hotels.s50-0-d6773.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-South-San-Francisco-Hotels.s50-0-d6773.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South San Francisco. ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Riu Plaza Fisherman's Wharf 2500 Mason St, San Francisco, CA CA $185 CA $276 total Oct 30 - Oct 31 includes taxes & fees 8.8/10 Excellent! (6,983 reviews) [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Hyatt Regency San Francisco](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency San Francisco 5 Embarcadero Center, San Francisco, CA CA $251 CA $362 total Oct 17 - Oct 18 includes taxes & fees 9.2/10 Wonderful! (1,934 reviews) [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton San Francisco Financial District 750 Kearny St, San Francisco, CA CA $180 CA $211 total Nov 9 - Nov 10 includes taxes & fees 8.6/10 Excellent! (1,874 reviews) [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) Still don't see what you're looking for? [See all properties in South San Francisco.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F10%2F2025&endDate=17%2F10%2F2025®ionId=6773&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F10%2F2025&endDate=17%2F10%2F2025®ionId=6773&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F10%2F2025&endDate=17%2F10%2F2025®ionId=6773&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F10%2F2025&endDate=17%2F10%2F2025®ionId=6773&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F10%2F2025&endDate=17%2F10%2F2025®ionId=6773&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F10%2F2025&endDate=17%2F10%2F2025®ionId=6773&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about South San Francisco South San Francisco is calling! Discover its food, castle, sightseeing, and more. [See all hotels in South San Francisco](https://www.expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30&adults=2®ionId=6773) ![](https://mediaim.expedia.com/destination/9/edf3b75ded644f2805fb6e835771cc8f.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top South San Francisco Hotel Reviews ![Claremont Resort & Club](//images.trvl-media.com/lodging/1000000/10000/6700/6609/d997dca7_y.jpg) ### Claremont Resort & Club 10/10 Excellent "Beautiful, classic property. Great art and views." [](https://expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information) ![Fairmont San Francisco](//images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "amazing property" [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ## Find out more about South San Francisco ## Five Star Hotels in South San Francisco There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made South San Francisco so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in South San Francisco and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in South San Francisco Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to South San Francisco The results are in, and South San Francisco 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in South San Francisco! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in South San Francisco today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in South San Francisco? > Based on Expedia guest reviews, [The St. Regis San Francisco](https://www.expedia.ca/San-Francisco-Hotels-The-St-Regis-San-Francisco.h1321986.Hotel-Information), [Four Seasons Hotel San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco.h791769.Hotel-Information) and [Mansion on Sutter](https://www.expedia.ca/San-Francisco-Hotels-Mansion-On-Sutter.h7064385.Hotel-Information) are among the leading 5-star hotels in South San Francisco. Offering best-in-class amenities and exemplary service, you can expect an indulgent and comfortable stay. ### How much does it cost to stay in a 5-star hotel in South San Francisco? > How much you pay for a 5-star hotel in South San Francisco can vary based on when you decide to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to land the best rate on a luxurious getaway. > > > > - Search for the lowest price per night from CA $211 ### What makes a hotel 5 stars in South San Francisco? > Exemplary guest service is the foundation of every 5-star hotel in South San Francisco. From the instant you arrive, staff attend to your every whim, whether recommending activities or providing a nightly turn-down service. In addition, hotels have to feature upscale conveniences to be considered for a 5-star rating. 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[Flights from Detroit (DTW) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/dtw/sfo/detroit-to-san-francisco) - [Flights from Los Angeles (LAX) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/lax/sfo/los-angeles-to-san-francisco) - [Flights from Seattle (SEA) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/sea/sfo/seattle-to-san-francisco) - [Flights from Edmonton (YEG) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco) - [Flights from Ottawa (YOW) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yow/sfo/ottawa-to-san-francisco) - [Flights from Montreal (YUL) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco) - [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco) - [Flights from Winnipeg (YWG) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/ywg/sfo/winnipeg-to-san-francisco) - [Flights from Calgary (YYC) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco) - [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco) - [Visit Paradise Valley](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811) - [Car rentals near SFO Museum](https://www.expedia.ca/Car-Rentals-In-SFO-Museum.d553248621555611878.Car-Rental-Guide) - [Car rental San Bruno](https://www.expedia.ca/Car-Rentals-In-San-Bruno.d6633.Car-Rental-Guide) - [Rental cars San Francisco Intl. airport](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide) - [Enterprise Rental Cars in San Bruno](https://www.expedia.ca/Enterprise-Car-Rentals-In-San-Bruno.d6633-c15.Car-Rental-Guide-Suppliers) - [Things to do in San Bruno](https://www.expedia.ca/Things-To-Do-In-San-Bruno.d6633.Travel-Guide-Activities) - [Book 5 Star Hotels in South San Francisco on Expedia.com](https://www.expedia.com/5Star-South-San-Francisco-Hotels.s50-0-d6773.Travel-Guide-Filter-Hotels)