Title: 5 Stars Hotels in Serra Mesa, San Diego from CA $182 - Find Cheap Serra Mesa Hotels With 5 Stars | Expedia.ca [Serra Mesa Travel Guide](https://expedia.ca/San-Diego-Serra-Mesa.dx553248635953501652)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Serra Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Serra-Mesa.d553248635953501652.Car-Rental-Guide)[Serra Mesa Vacations](https://expedia.ca/Serra-Mesa.d553248635953501652.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Serra Mesa, San Diego from CA $182 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Serra Mesa 5 Star Hotels Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-05&endDate=2025-10-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-06&endDate=2025-10-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Serra Mesa 5 Star Hotels ![3 restaurants, breakfast, lunch, dinner served; seafood](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/a2e0b6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/ffc5e031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/0c2ef40d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pendry San Diego Downtown San Diego 9.2/10 Wonderful (1009) "Great room and staff, restaurant is also very good " CA $356 CA $486 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/e71c0bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/w4000h2663x0y0-0937aebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/10ea342c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/61ab8b94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The US Grant, a Luxury Collection Hotel, San Diego Downtown San Diego 9.0/10 Wonderful (1007) "The staff was excellent and attentive. It was centrally located to all we wished to visit" CA $388 CA $450 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Diego-Hotels-THE-US-GRANT.h10802.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/2994db0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/63ea3d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/6b1cc62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/149c7006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L'Auberge Del Mar Del Mar 8.6/10 Excellent (810) "Top tier service and location " CA $557 CA $726 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Del-Mar-Hotels-LAuberge-Del-Mar.h5079.Hotel-Information) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/28300/28264/998bcad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Gamble) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/28300/28264/dbb1ec46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Blacker)](https://images.trvl-media.com/lodging/1000000/30000/28300/28264/9d86fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/28300/28264/087d6b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Torrey Pines Torrey Pines 9.2/10 Wonderful (855) "The hotel rooms were clean and the staff were very friendly. " CA $557 CA $738 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/La-Jolla-Hotels-The-Lodge-At-Torrey-Pines.h28264.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1780000/1779800/1779742/d14e7124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/2000000/1780000/1779800/1779742/9ab7bf07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1780000/1779800/1779742/b12af9a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1780000/1779800/1779742/d7a843a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairmont Grand Del Mar Carmel Valley 9.6/10 Exceptional (898) "Great hotel. " CA $933 CA $1,186 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/San-Diego-Hotels-Fairmont-Grand-Del-Mar.h1779742.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/fe94f9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/2b448002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, ocean views ](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/889d28b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/178c1eb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bower Coronado Historic Downtown Coronado 9.2/10 Wonderful (112) "Great hotel " CA $338 CA $441 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Coronado-Hotels-The-Bower.h111958344.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/eaeb791a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/e17e30fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/e0260017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Horizon Suite) | Living area](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/bf3cf5a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beach Village at The Del, LXR Hotels & Resorts Historic Downtown Coronado 9.2/10 Wonderful (117) "Best place I’ve ever stayed " CA $1,030 CA $1,204 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Coronado-Hotels-Beach-Village-At-The-Del.h19656437.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15600/15525/469088ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15600/15525/d42c797c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/20000/15600/15525/dd10c38e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15600/15525/66a30957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn At Rancho Santa Fe Covenant 9.6/10 Exceptional (130) "Absolutely beautiful " CA $627 CA $701 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Rancho-Santa-Fe-Hotels-Inn-At-Rancho-Santa-Fe.h15525.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/17600/17535/eb69ba1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/20000/17600/17535/02f2dbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Hacienda)](https://images.trvl-media.com/lodging/1000000/20000/17600/17535/0e996e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/20000/17600/17535/e4589e16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rancho Valencia Resort and Spa Rancho Santa Fe 9.8/10 Exceptional (137) "It was a perfect get away for our anniversary!" CA $1,518 CA $1,748 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rancho-Santa-Fe-Hotels-Rancho-Valencia-Resort-And-Spa.h17535.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Serra-Mesa-San-Diego-Hotels.s50-n553248635953501652-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Serra-Mesa-San-Diego-Hotels.s50-n553248635953501652-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Serra Mesa. ![Hotel del Coronado, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel del Coronado, Curio Collection by Hilton 1500 Orange Ave, Coronado, CA CA $434 CA $560 total Oct 29 - Oct 30 includes taxes & fees 8/10 Very Good! (1,048 reviews) [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Wyndham San Diego Bayside 1355 N Harbor Drive, San Diego, CA CA $212 CA $287 total Oct 7 - Oct 8 includes taxes & fees 8.2/10 Very Good! (5,952 reviews) [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Palihotel San Diego Gaslamp Quarter](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Palihotel San Diego Gaslamp Quarter 830 Sixth Avenue, San Diego, CA CA $157 CA $182 total Oct 12 - Oct 13 includes taxes & fees 8.6/10 Excellent! (1,861 reviews) [](https://expedia.ca/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) Still don't see what you're looking for? [See all properties in Serra Mesa.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=553248635953501652&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=553248635953501652&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=553248635953501652&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=553248635953501652&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=553248635953501652&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=553248635953501652&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Serra Mesa Hotel Reviews ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Hotel is pretty and is in a great location to be able to walk to shops, restaurants and bars " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Serra Mesa? > How much you pay for a 5-star hotel in Serra Mesa can vary depending on when you prefer to travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to find the best deal on a luxurious getaway. > > > > - Search for the lowest price per night from CA $182 ### What makes a hotel 5 stars in Serra Mesa? > Exemplary guest service is at the heart of every 5-star hotel in Serra Mesa. From the instant you arrive, staff attend to your every whim, whether arranging customized tours or providing a nightly turn-down service. On top of that, hotels must feature superior conveniences to be considered for a 5-star rating. These can include deluxe baths, saunas or spas, swimming pools, fine dining restaurants and knowledgeable concierge. ### Are there any 5-star all-inclusive resorts in Serra Mesa? > Find an upscale retreat that includes your lodging, food, activities and entertainment in Serra Mesa with the help of our filter tool. Search for resorts with a 5-star rating and select the "All inclusive" filter. Be sure to check what's included in the price. 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