Title: 5 Stars Hotels in Port Isabel, Texas from CA $143 - Find Cheap Port Isabel Hotels With 5 Stars | Expedia.ca [Port Isabel Travel Guide](https://expedia.ca/Port-Isabel.dx184007)[Hotels in Port Isabel](https://expedia.ca/Port-Isabel-Hotels.d184007.Travel-Guide-Hotels)[Vacation Rentals in Port Isabel](https://expedia.ca/Port-Isabel-Vacation-Rentals.d184007.Travel-Guide-VacationRentals)[Flights to Port Isabel](https://expedia.ca/Cheap-Flights-To-Port-Isabel.d184007.Travel-Guide-Flights)[Things to do in Port Isabel](https://expedia.ca/Things-To-Do-In-Port-Isabel.d184007.Travel-Guide-Activities)[Port Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Port-Isabel.d184007.Car-Rental-Guide)[Port Isabel Vacation Packages](https://expedia.ca/Port-Isabel.d184007.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/6eb3b856eb8d266fbe19de2b663e7a1b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Port Isabel, Texas from CA $143 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Port Isabel 5 Star Hotels Tonight [Nov 8 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-08&endDate=2025-11-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-09&endDate=2025-11-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-21&endDate=2025-11-23&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Port Isabel 5 Star Hotels ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114590000/114587100/114587056/07a3b6d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 5 Bedrooms, Private Pool, Bay View | Private kitchen](https://images.trvl-media.com/lodging/115000000/114590000/114587100/114587056/9d28fae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 5 Bedrooms, Private Pool, Bay View](https://images.trvl-media.com/lodging/115000000/114590000/114587100/114587056/4dfbe304.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort House, 5 Bedrooms, Bay View, Poolside | Private kitchen](https://images.trvl-media.com/lodging/115000000/114590000/114587100/114587056/a9dc28dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious Bay Port Isabel [](https://www.expedia.ca/Port-Isabel-Hotels-5Bedroom-Single-Family-Home.h114587056.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Port-Isabel-Hotels.s50-0-d184007.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Port-Isabel-Hotels.s50-0-d184007.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Port Isabel. ![Margaritaville Beach Resort South Padre Island ](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/6db563a5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Beach Resort South Padre Island 310 Padre Blvd, South Padre Island, TX CA $108 CA $143 total Nov 17 - Nov 18 includes taxes & fees 8.6/10 Excellent! (1,771 reviews) [](https://expedia.ca/South-Padre-Island-Hotels-Pearl-South-Padre.h21996.Hotel-Information) ![Sea Vista by South Padre Condo Rentals](https://images.trvl-media.com/lodging/11000000/10660000/10650400/10650383/8a8d29ae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sea Vista by South Padre Condo Rentals 110 Padre Blvd, South Padre Island, TX [Get rates](https://expedia.ca/Hotel-Search?startDate=22%2F11%2F2025&endDate=23%2F11%2F2025&selected=10650383&PinnedHotelID=10650383&HadPinnedHotel=true®ionId=184007) 8.8/10 Excellent! (54 reviews) [](https://expedia.ca/South-Padre-Island-Hotels-Sea-Vista-By-South-Padre-Condo-Rentals.h10650383.Hotel-Information) ![Sleeps 6 in a 4plex w Pool, Only a Block to Beach](https://images.trvl-media.com/lodging/97000000/96300000/96290200/96290152/2ccb859c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleeps 6 in a 4plex w Pool, Only a Block to Beach 124 E Saturn Ln, South Padre Island, TX [Get rates](https://expedia.ca/Hotel-Search?startDate=22%2F11%2F2025&endDate=23%2F11%2F2025&selected=96290152&PinnedHotelID=96290152&HadPinnedHotel=true®ionId=184007) [](https://expedia.ca/South-Padre-Island-Hotels-Emerald-Breeze-3.h96290152.Hotel-Information) Still don't see what you're looking for? [See all properties in Port Isabel.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F11%2F2025&endDate=10%2F11%2F2025®ionId=184007&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F11%2F2025&endDate=10%2F11%2F2025®ionId=184007&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F11%2F2025&endDate=10%2F11%2F2025®ionId=184007&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F11%2F2025&endDate=10%2F11%2F2025®ionId=184007&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F11%2F2025&endDate=10%2F11%2F2025®ionId=184007&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F11%2F2025&endDate=10%2F11%2F2025®ionId=184007&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Port Isabel Climb the historic lighthouse for sweeping views of South Padre Island and spot dolphins playing in the turquoise waters. Explore the treasures at Pirates Landing pier, where fishing adventures and fresh seafood restaurants create the perfect coastal getaway. [See all hotels in Port Isabel](https://www.expedia.ca/Hotel-Search?startDate=2025-11-22&endDate=2025-11-23&adults=2®ionId=184007) ![C982YC Port Isabel Lighthouse, near Brownsville, Texas, USA](https://images.trvl-media.com/place/184007/83ec1fb8-b7d2-43e0-a593-9051073c7efc.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Port Isabel Hotel Reviews ## Find out more about Port Isabel ## Five Star Hotels in Port Isabel There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Port Isabel so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Port Isabel and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Port Isabel Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Port Isabel The results are in, and Port Isabel 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Port Isabel! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Port Isabel today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Port Isabel? > How much you pay for a 5-star hotel in Port Isabel can vary depending on the time of year you travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to find the best deal on a plush stay. > > > > - Search for the lowest price per night from CA $143 ### What makes a hotel 5 stars in Port Isabel? > From fine dining restaurants and 24-hour fitness centres to swimming pools and deluxe bedding, the 5-star experience in Port Isabel is all about indulgence and comfort. But it calls for more than just upscale amenities to earn a 5-star rating. Stays also have to offer remarkable guest services like in-room beauty treatments, on-site laundry and 24/7 room service. ### Are there any 5-star all-inclusive resorts in Port Isabel? > Expedia's filters are the quickest way to find exactly what you're looking for. Select "All inclusive" and "5-star" to see the most luxurious properties in Port Isabel where your accommodations, meals, activities and entertainment are included in the price. At these getaways, your vacation is absolute indulgence from the moment you step foot in the lobby. ## Explore a world of travel with Expedia - More ways to book - [Book 5 Star Hotels in Port Isabel on Expedia.com](https://www.expedia.com/5Star-Port-Isabel-Hotels.s50-0-d184007.Travel-Guide-Filter-Hotels)