Title: 5 Stars Hotels in Ohio River Valley, United States of America from CA $133 - Find Cheap Ohio River Valley Hotels With 5 Stars | Expedia.ca [Ohio River Valley Travel Guide](https://expedia.ca/Ohio-River-Valley.dx6233674)[Hotels in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels)[Vacation Rentals in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Vacation-Rentals.d6233674.Travel-Guide-VacationRentals)[Flights to Ohio River Valley](https://expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)[Ohio River Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Ohio-River-Valley.d6233674.Car-Rental-Guide)[Ohio River Valley Vacation Packages](https://expedia.ca/Ohio-River-Valley.d6233674.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/d8d7cee1461f7acfeb618115e5af115c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Ohio River Valley, United States of America from CA $133 ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check availability on Ohio River Valley 5 Star Hotels Tonight [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-07&endDate=2025-10-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-08&endDate=2025-10-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Ohio River Valley 5 Star Hotels ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105292/9aff277c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105292/8e09d608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | City view](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105292/666f4f4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105292/432978f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Méridien Columbus, The Joseph Downtown Columbus 9.2/10 Wonderful (626) "The hotel is in the perfect location and modern and beautiful. " CA $212 CA $250 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Columbus-Hotels-Le-Meridien-Columbus.h9105292.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/w3822h2860x18y0-dc47fc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/w2558h3836x3y4-7244cc45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/b16740d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/3cf8c2c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Conrad Indianapolis Downtown Indianapolis 9.2/10 Wonderful (1005) "Stayed in the Modern Suite. Very nice room! Close to restaurants and walking distance to Lucas Oil Stadium. Would definitely stay here again. " CA $296 CA $350 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Indianapolis-Hotels-Conrad-Indianapolis.h1287480.Hotel-Information) ![32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95420000/95419700/95419604/27772668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95420000/95419700/95419604/7a3e6730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95420000/95419700/95419604/5fce62fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95420000/95419700/95419604/8c04b7db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jungle Fever Downtown Columbus 10/10 Exceptional (5) "The property had a unique vibe and was very spacious and comfortable. We would stay here again for sure!" CA $62 CA $181 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Columbus-Hotels-Jungle-Fever.h95419604.Hotel-Information) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95420000/95419600/95419544/6840c77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/96000000/95420000/95419600/95419544/9d5e7dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/96000000/95420000/95419600/95419544/898621a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/96000000/95420000/95419600/95419544/0b2cc437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Jungle Oasis Downtown Columbus 10/10 Exceptional (6) "Had a great time! " CA $58 CA $133 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Columbus-Hotels-The-Jungle-Oasis.h95419544.Hotel-Information) ![Dining room](https://images.trvl-media.com/lodging/96000000/95420000/95419800/95419714/5cd0ed67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, memory foam beds](https://images.trvl-media.com/lodging/96000000/95420000/95419800/95419714/1570a08b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, Netflix, Hulu, books](https://images.trvl-media.com/lodging/96000000/95420000/95419800/95419714/825d1355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Separate tub and shower, rainfall showerhead, eco-friendly toiletries](https://images.trvl-media.com/lodging/96000000/95420000/95419800/95419714/72f0445e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jungalow Downtown Columbus 10/10 Exceptional (7) "This property was more than I could have ever expected! It looks like something out of HGTV. It’s absolutely gorgeous and so many tiny unique details. The beds are very comfortable, lots of towels in the gorgeous bathroom and the kitchen is fully stocked with everything for preparing meals. Unfortunately we were only staying for one night but I will absolutely be booking here again! Things to keep in mind tho, the top floor bedroom with 2 beds has VERY steep and narrow steps so if you have... CA $65 CA $185 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Columbus-Hotels-Jungalow.h95419714.Hotel-Information) ![Street view](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/ef55443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/c8e026b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/00819013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/90f511a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Louisville Bourbon Inn Old Louisville 10/10 Exceptional (17) "Absolutely the best B&B we have ever stayed with." CA $370 CA $429 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Louisville-Hotels-Louisville-Bourbon-Inn.h101176472.Hotel-Information) ![Design House | Living area](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419409/59c4a5dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design House | Private kitchen](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419409/64e44d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design House | Living area](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419409/aec2a8b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design House | Living area](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419409/1aa65a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Jungle Book Downtown Columbus 10/10 Exceptional (3) "We had a wonderful stay ! The place was clean , comfortable, and perfectly located. Our host Sergio was super responsive and made sure we had everything we needed. Highly recommend! " CA $72 CA $172 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Columbus-Hotels-The-Jungle-Book.h95419409.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Ohio-River-Valley-Hotels.s50-0-d6233674.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Ohio-River-Valley-Hotels.s50-0-d6233674.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ohio River Valley. ![Sonesta Columbus Downtown](https://images.trvl-media.com/lodging/1000000/30000/26900/26870/d5b1e434_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sonesta Columbus Downtown 33 E Nationwide Blvd, Columbus, OH CA $184 CA $251 total Nov 2 - Nov 3 includes taxes & fees 8.6/10 Excellent! (1,455 reviews) [](https://expedia.ca/Columbus-Hotels-Sonesta-Columbus.h26870.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galt House Hotel Trademark Collection by Wyndham 140 North Fourth Street, Louisville, KY CA $194 CA $228 total Nov 1 - Nov 2 includes taxes & fees 8.8/10 Excellent! (3,655 reviews) [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![I Hotel And Illinois Conference Center](https://images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/b24d7833_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### I Hotel And Illinois Conference Center 1900 South First Street, Champaign, IL CA $141 CA $159 total Oct 12 - Oct 13 includes taxes & fees 9.6/10 Exceptional! (1,831 reviews) [](https://expedia.ca/Champaign-Hotels-I-Hotel-And-Conference-Center.h1897350.Hotel-Information) Still don't see what you're looking for? [See all properties in Ohio River Valley.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F10%2F2025&endDate=09%2F10%2F2025®ionId=6233674&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F10%2F2025&endDate=09%2F10%2F2025®ionId=6233674&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F10%2F2025&endDate=09%2F10%2F2025®ionId=6233674&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F10%2F2025&endDate=09%2F10%2F2025®ionId=6233674&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F10%2F2025&endDate=09%2F10%2F2025®ionId=6233674&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F10%2F2025&endDate=09%2F10%2F2025®ionId=6233674&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Ohio River Valley Lively festivals, beloved sports teams, and top sights from Lucas Oil Stadium to Ark Encounter—discover Ohio River Valley, a historic destination also famous for its college vibe. [See all hotels in Ohio River Valley](https://www.expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22&adults=2®ionId=6233674) ![Indianapolis featuring autumn leaves and a cemetery](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25344-Indianapolis.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Ohio River Valley Hotel Reviews ## Find out more about Ohio River Valley Luxury is the name of the game at the best 5 Stars hotels in Ohio River Valley. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Ohio River Valley 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Ohio River Valley hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Ohio River Valley without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Ohio River Valley. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Ohio River Valley? > The amount you pay for a 5-star hotel in Ohio River Valley depends on factors such as when you want to go and the length of your vacation. An insider tip for landing the best deal? Use our pricing filters to check out all of the available options for your selected dates. > > > > - Search for the lowest price per night from CA $159 ### What makes a hotel 5 stars in Ohio River Valley? > Outstanding guest service is at the heart of every 5-star hotel in Ohio River Valley. From the minute you step through the door, staff attend to your every whim, whether recommending activities and tours or providing in-room beauty treatments. In addition, hotels have to offer superior amenities to qualify for a 5-star rating. These can include luxury bathrooms, on-site spa facilities, swimming pools, gourmet kitchens and knowledgeable concierge. ### Are there any 5-star all-inclusive resorts in Ohio River Valley? > Find an upscale stay that includes your lodging, food, activities and entertainment in Ohio River Valley with Expedia's filters. Search for hotels rated 5 stars and select the "All inclusive" filter. Have a look at what's included in the upfront price. That way, you'll be ready to maximize the premium perks on offer from the moment you step into the lobby. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Historic Route 66](https://www.expedia.ca/1Star-Historic-Route-66-Hotels.s10-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Historic Route 66](https://www.expedia.ca/2Star-Historic-Route-66-Hotels.s20-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [B&B in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Bed-And-Breakfast.d702654640613646336-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Cabins.d702654640613646336-aaCabins.Travel-Guide-Accommodation) - [Chalets in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Chalets.d702654640613646336-aaChalets.Travel-Guide-Accommodation) - [Condo Rentals in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Condos.d702654640613646336-aaCondos.Travel-Guide-Accommodation) - [Cottages in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Cottages.d702654640613646336-aaCottages.Travel-Guide-Accommodation) - [Hostels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hostels.d702654640613646336-aaHostels.Travel-Guide-Accommodation) - [Cheap Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Cheap-Hotels.0-0-d702654640613646336-tCheapHotels.Travel-Guide-Filter-Hotels) - [Club Quarters Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Club-Quarters.0-0-d702654640613646336--bClubQuarters.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Luxury-Hotel.0-0-d702654640613646336-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Motel-6.0-0-d702654640613646336--bMotel6.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Red-Roof-Inn.0-0-d702654640613646336--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Sonesta Hotel in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Sonesta-Hotel.0-0-d702654640613646336--bSonestaHotel.Travel-Guide-Filter-Hotels) - [Wyndham Extra Holidays Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Wyndham-Extra-Holidays.0-0-d702654640613646336--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels) - [Historic Route 66 Hotels](https://www.expedia.ca/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels) - [Inns in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Inns.d702654640613646336-aaInns.Travel-Guide-Accommodation) - [Lodges in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Lodges.d702654640613646336-aaLodges.Travel-Guide-Accommodation) - [Motels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Motels.d702654640613646336-aaMotels.Travel-Guide-Accommodation) - [Resorts in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Resort-Hotels.d702654640613646336-aaResortHotels.Travel-Guide-Accommodation) - [Hotels near Ohio River](https://www.expedia.ca/Ohio-River-Hotels.0-l681940626945888256-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Boutique-Hotel.0-0-d6233889-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Casino-Hotel.0-0-d6233889-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Couples-Resorts-Hotels.0-0-d6233889-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Hotels-With-Smoking-Rooms.0-0-d6233889-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Red-Roof-Inn.0-0-d6233889--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Waterpark-Hotels.0-0-d6233889-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Southeastern Indiana Hotels](https://www.expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels) - [Motels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Motels.d6233889-aaMotels.Travel-Guide-Accommodation) - [B&B in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Bed-And-Breakfast.d6059635-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Cabins.d6059635-aaCabins.Travel-Guide-Accommodation) - [Chalets in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Chalets.d6059635-aaChalets.Travel-Guide-Accommodation) - [Hostels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hostels.d6059635-aaHostels.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Beach-Hotel.0-0-d6059635-tBeachHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Casino-Hotel.0-0-d6059635-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Cheap-Hotels.0-0-d6059635-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hilton-Hotels.0-0-d6059635--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hotels-With-Free-Parking.0-0-d6059635-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hotels-With-Hot-Tubs.0-0-d6059635-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hotels-With-Tennis-Courts.0-0-d6059635-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-La-Quinta-Inn-Suites.0-0-d6059635--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Luxury-Hotel.0-0-d6059635-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Marriott-Hotels-Resorts.0-0-d6059635--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Omni Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Omni.0-0-d6059635--bOmni.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Pet-Friendly-Hotel.0-0-d6059635-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Red-Roof-Inn.0-0-d6059635--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Romantic-Hotel.0-0-d6059635-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Waterpark-Hotels.0-0-d6059635-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Southern Indiana Hotels](https://www.expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels) - [Motels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Motels.d6059635-aaMotels.Travel-Guide-Accommodation) - [Resorts in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Resort-Hotels.d6059635-aaResortHotels.Travel-Guide-Accommodation) - [Cheap Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Cheap-Hotels.0-0-d6233876-tCheapHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Historic-Hotel.0-0-d6233876-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Hotels-With-Hot-Tubs.0-0-d6233876-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Pet-Friendly-Hotel.0-0-d6233876-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Red-Roof-Inn.0-0-d6233876--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Southwestern Indiana Hotels](https://www.expedia.ca/Southwestern-Indiana-Hotels.d6233876.Travel-Guide-Hotels) - [Resorts in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Resort-Hotels.d6233876-aaResortHotels.Travel-Guide-Accommodation) - [Flights to Historic Route 66](https://www.expedia.ca/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights) - [Flights to Southern Indiana](https://www.expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights) - [Flights to Southwestern Indiana](https://www.expedia.ca/Cheap-Flights-To-Southwestern-Indiana.d6233876.Travel-Guide-Flights) - [Flights from Atlanta to Southern Indiana](https://www.expedia.ca/lp/flights/178232/6059635/atlanta-to-southern-indiana) - [Flights from Philadelphia to Southern Indiana](https://www.expedia.ca/lp/flights/178297/6059635/philadelphia-to-southern-indiana) - [Flights from Phoenix to Historic Route 66](https://www.expedia.ca/lp/flights/178298/702654640613646336/phoenix-to-historic-route-66) - [Flights from Seattle to Southern Indiana](https://www.expedia.ca/lp/flights/178307/6059635/seattle-to-southern-indiana) - [Flights from Buffalo to Southern Indiana](https://www.expedia.ca/lp/flights/602674/6059635/buffalo-to-southern-indiana) - [Historic Route 66 Vacations](https://www.expedia.ca/Historic-Route-66.d702654640613646336.Destination-Travel-Guides) - [Southern Indiana Vacations](https://www.expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides) - [Visit Southern Indiana](https://www.expedia.ca/Southern-Indiana.dx6059635) - [Visit Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana.dx6233876) - [Ada Rental Cars in Historic Route 66](https://www.expedia.ca/ADA-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1109.Car-Rental-Guide-Suppliers) - [Airport Van Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Airport-Van-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1092.Car-Rental-Guide-Suppliers) - [Amigo Autos Rental Cars in Historic Route 66](https://www.expedia.ca/Amigo-Autos-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1128.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Historic Route 66](https://www.expedia.ca/Avis-Car-Rentals-In-Historic-Route-66.d702654640613646336-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Historic Route 66](https://www.expedia.ca/Car-Rentals-In-Historic-Route-66.d702654640613646336.Car-Rental-Guide) - [Click & Rent Rental Cars in Historic Route 66](https://www.expedia.ca/Click-Rent-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1089.Car-Rental-Guide-Suppliers) - [Convertible Car Rentals in Historic Route 66](https://www.expedia.ca/Convertible-Car-Rentals-In-Historic-Route-66.d702654640613646336-tConvertible.Car-Rental-Guide-Class) - [Drive-A-Matic Rental Cars in Historic Route 66](https://www.expedia.ca/Drive-A-Matic-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1082.Car-Rental-Guide-Suppliers) - [Drive on Holidays Rental Cars in Historic Route 66](https://www.expedia.ca/Drive-On-Holidays-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1050.Car-Rental-Guide-Suppliers) - [Firefly Rental Cars in Historic Route 66](https://www.expedia.ca/Firefly-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1040.Car-Rental-Guide-Suppliers) - [Firefly Portugal Rental Cars in Historic Route 66](https://www.expedia.ca/Firefly-Portugal-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1071.Car-Rental-Guide-Suppliers) - [First Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/First-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1107.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Historic Route 66](https://www.expedia.ca/Hertz-Car-Rentals-In-Historic-Route-66.d702654640613646336-c40.Car-Rental-Guide-Suppliers) - [Jumbo Car Rental Cars in Historic Route 66](https://www.expedia.ca/Jumbo-Car-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1067.Car-Rental-Guide-Suppliers) - [Luxury Car Rentals in Historic Route 66](https://www.expedia.ca/Luxury-Car-Rentals-In-Historic-Route-66.d702654640613646336-tLuxury.Car-Rental-Guide-Class) - [Midway Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Midway-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c27.Car-Rental-Guide-Suppliers) - [National Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c42.Car-Rental-Guide-Suppliers) - [Offer Car Hire Rental Cars in Historic Route 66](https://www.expedia.ca/Offer-Car-Hire-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1141.Car-Rental-Guide-Suppliers) - [Orlando Rental Cars in Historic Route 66](https://www.expedia.ca/Orlando-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1047.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in Historic Route 66](https://www.expedia.ca/Pickup-Car-Rentals-In-Historic-Route-66.d702654640613646336-tPickup.Car-Rental-Guide-Class) - [Priceless Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Priceless-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1060.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Historic Route 66](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Historic-Route-66.d702654640613646336-c33.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Southern Indiana](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Southern-Indiana.d6059635-c33.Car-Rental-Guide-Suppliers) - [Routes Rental Cars in Historic Route 66](https://www.expedia.ca/Routes-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1101.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Historic Route 66](https://www.expedia.ca/Thai-Cars-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1027.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c45.Car-Rental-Guide-Suppliers) - [Van Car Rentals in Historic Route 66](https://www.expedia.ca/Van-Car-Rentals-In-Historic-Route-66.d702654640613646336-tVan.Car-Rental-Guide-Class) - [Wiber Rental Cars in Historic Route 66](https://www.expedia.ca/WIber-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1127.Car-Rental-Guide-Suppliers) - [Historic Route 66 Vacation Rentals](https://www.expedia.ca/Historic-Route-66-Vacation-Rentals.d702654640613646336.Travel-Guide-VacationRentals) - [Things to do in Southern Indiana](https://www.expedia.ca/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities) - [Book 5 Star Hotels in Ohio River Valley on Expedia.com](https://www.expedia.com/5Star-Ohio-River-Valley-Hotels.s50-0-d6233674.Travel-Guide-Filter-Hotels)