Title: 5 Stars Hotels in Matlacha Isles, Cape Coral from CA $191 - Find Cheap Matlacha Isles Hotels With 5 Stars | Expedia.ca [Matlacha Isles Travel Guide](https://expedia.ca/Cape-Coral-Matlacha-Isles.dx553248635976471942)[Vacation Rentals in Cape Coral](https://expedia.ca/Cape-Coral-Vacation-Rentals.d6521.Travel-Guide-VacationRentals)[Flights to Cape Coral](https://expedia.ca/Cheap-Flights-To-Cape-Coral.d6521.Travel-Guide-Flights)[Things to do in Cape Coral](https://expedia.ca/Things-To-Do-In-Cape-Coral.d6521.Travel-Guide-Activities)[Matlacha Isles Car Rentals](https://expedia.ca/Car-Rentals-In-Matlacha-Isles.d553248635976471942.Car-Rental-Guide)[Matlacha Isles Vacations](https://expedia.ca/Matlacha-Isles.d553248635976471942.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Matlacha Isles, Cape Coral from CA $191 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Matlacha Isles 5 Star Hotels Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2025-11-02&endDate=2025-11-03&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2025-11-03&endDate=2025-11-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Matlacha Isles 5 Star Hotels ![2 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/5481c209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/62d93321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/c6ba33ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/f4e5c65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sundial Beach Resort & Spa Mid Island 8.6/10 Excellent (2579) "Thank you for a great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $465 CA $595 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Sanibel-Hotels-Sundial-Beach-Resort-Spa.h1939.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Matlacha-Isles-Cape-Coral-Hotels.s50-n553248635976471942-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Matlacha-Isles-Cape-Coral-Hotels.s50-n553248635976471942-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Matlacha Isles. ![Margaritaville Beach Resort Fort Myers ](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Beach Resort Fort Myers 251 Crescent Street, Fort Myers Beach, FL CA $203 CA $297 total Nov 17 - Nov 18 includes taxes & fees 8.8/10 Excellent! (1,569 reviews) [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pink Shell Beach Resort and Marina 275 Estero Blvd, Fort Myers Beach, FL CA $286 CA $412 total Dec 2 - Dec 3 includes taxes & fees 9.4/10 Exceptional! (1,132 reviews) [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 13051 Bell Tower Drive, Fort Myers, FL CA $171 CA $191 total Dec 1 - Dec 2 includes taxes & fees 8.8/10 Excellent! (1,007 reviews) [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) Still don't see what you're looking for? [See all properties in Matlacha Isles.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976471942&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976471942&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976471942&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976471942&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976471942&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976471942&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Matlacha Isles Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [1 Star Hotels in Villas](https://www.expedia.ca/1Star-Villas-Fort-Myers-Hotels.s10-n553248628384480340-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Burnt Store](https://www.expedia.ca/2Star-Burnt-Store-Cape-Coral-Hotels.s20-n553248635976481229-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Eight Lakes](https://www.expedia.ca/2Star-Eight-Lakes-Cape-Coral-Hotels.s20-n553248635976481277-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in North Captiva](https://www.expedia.ca/2Star-North-Captiva-Captiva-Hotels.s20-n6177554-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Downtown Fort Myers Beach](https://www.expedia.ca/3Star-Downtown-Fort-Myers-Beach-Fort-Myers-Beach-Hotels.s30-n904326898430316544-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Estero](https://www.expedia.ca/3Star-Estero-Hotels.s30-0-d500699.Travel-Guide-Filter-Hotels) - 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[Bowland Coral Lanes](https://www.expedia.ca/Bowland-Coral-Lanes-Hancock.d553248621532652494.Vacation-Attraction) - [Coral Oaks Golf Course](https://www.expedia.ca/Coral-Oaks-Golf-Course-Burnt-Store.d6295914.Vacation-Attraction) - [Visit Matlacha Isles-Matlacha Shores](https://www.expedia.ca/Matlacha-Isles-Matlacha-Shores.dx553248635975849540) - [Mike Greenwell's Bat-A-Ball & Family Fun Park](https://www.expedia.ca/Mike-Greenwells-Bat-A-Ball-Family-Fun-Park-Hancock.d553248621532652495.Vacation-Attraction) - [Pine Island Vacations](https://www.expedia.ca/Pine-Island.d553248635083900600.Destination-Travel-Guides) - [Visit Pine Island](https://www.expedia.ca/Pine-Island.dx553248635083900600) - [Sun Splash Water Park](https://www.expedia.ca/Sun-Splash-Water-Park-Hancock.d6127772.Vacation-Attraction) - [Car rental Matlacha](https://www.expedia.ca/Car-Rentals-In-Matlacha.d601098.Car-Rental-Guide) - [Car rentals near Pine Island](https://www.expedia.ca/Car-Rentals-In-Pine-Island.d553248635083900600.Car-Rental-Guide) - [Zezgo Rental Cars in Pine Island](https://www.expedia.ca/ZezGo-Car-Rentals-In-Pine-Island.d553248635083900600-c1122.Car-Rental-Guide-Suppliers) - [Things to do in Matlacha](https://www.expedia.ca/Things-To-Do-In-Matlacha.d601098.Travel-Guide-Activities) - [Things to do in Pine Island](https://www.expedia.ca/Things-To-Do-In-Pine-Island.d553248635083900600.Travel-Guide-Activities) - [Book Hotels in Matlacha Isles on Expedia.com](https://www.expedia.com/5Star-Matlacha-Isles-Cape-Coral-Hotels.s50-n553248635976471942-0.Travel-Guide-Filter-Hotels)