Title: 5 Stars Hotels in East Seneca, Buffalo from CA $169 - Find Cheap East Seneca Hotels With 5 Stars | Expedia.ca [East Seneca Travel Guide](https://expedia.ca/Buffalo-East-Seneca.dx553248635975848496)[Vacation Rentals in Buffalo](https://expedia.ca/Buffalo-Vacation-Rentals.d717.Travel-Guide-VacationRentals)[East Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-East-Seneca.d553248635975848496.Car-Rental-Guide)[East Seneca Vacations](https://expedia.ca/East-Seneca.d553248635975848496.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in East Seneca, Buffalo from CA $169 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on East Seneca 5 Star Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-18&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-19&endDate=2025-10-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top East Seneca 5 Star Hotels ![2 bars/lounges](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/1b8dbb7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/727bae68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/bde93c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot springs](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/65405b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Curtiss Hotel, an Ascend Collection Hotel Downtown Buffalo 9.2/10 Wonderful (1017) "Nice hotel" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $349 CA $408 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-East-Seneca-Buffalo-Hotels.s50-n553248635975848496-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-East-Seneca-Buffalo-Hotels.s50-n553248635975848496-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in East Seneca. ![The Mansion On Delaware Ave](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Mansion On Delaware Ave 414 Delaware Ave, Buffalo, NY CA $213 CA $245 total Nov 17 - Nov 18 includes taxes & fees 9.2/10 Wonderful! (1,008 reviews) [](https://expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) ![The Delavan Hotel & Spa](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/c468db44_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Delavan Hotel & Spa 6461 Transit Road, Bowmansville, NY CA $175 CA $200 total Oct 30 - Oct 31 includes taxes & fees 8.8/10 Excellent! (1,007 reviews) [](https://expedia.ca/Buffalo-Hotels-The-Delavan-Hotel-Spa.h15031117.Hotel-Information) ![DoubleTree by Hilton Hotel Buffalo - Amherst](https://images.trvl-media.com/lodging/1000000/10000/3000/2914/e3e45ea5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### DoubleTree by Hilton Hotel Buffalo - Amherst 10 Flint Rd, Buffalo, NY CA $148 CA $169 total Nov 10 - Nov 11 includes taxes & fees 7.8/10 Good! (1,009 reviews) [](https://expedia.ca/Buffalo-Hotels-DoubleTree-By-Hilton-Hotel-Buffalo-Amherst.h2914.Hotel-Information) Still don't see what you're looking for? [See all properties in East Seneca.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=553248635975848496&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=553248635975848496&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=553248635975848496&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=553248635975848496&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=553248635975848496&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=553248635975848496&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top East Seneca Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Buffalo](https://www.expedia.ca/1Star-Buffalo-Hotels.s10-0-d602674.Travel-Guide-Filter-Hotels) - [1 Star Hotels in Niagara Falls](https://www.expedia.ca/1Star-Niagara-Falls-Hotels.s10-0-d602721.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Amherst](https://www.expedia.ca/2Star-Amherst-Hotels.s20-0-d9323.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Buffalo](https://www.expedia.ca/2Star-Buffalo-Hotels.s20-0-d602674.Travel-Guide-Filter-Hotels) - [2 Star Hotels in East Aurora](https://www.expedia.ca/2Star-East-Aurora-Hotels.s20-0-d7952.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Niagara Falls](https://www.expedia.ca/2Star-Niagara-Falls-Hotels.s20-0-d602721.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Amherst](https://www.expedia.ca/3Star-Amherst-Hotels.s30-0-d9323.Travel-Guide-Filter-Hotels) - 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