Title: 5 Stars Hotels in East Seneca, Buffalo from CA $134 - Find Cheap East Seneca Hotels With 5 Stars | Expedia.ca [East Seneca Travel Guide](https://expedia.ca/Buffalo-East-Seneca.dx553248635975848496)[Vacation Rentals in Buffalo](https://expedia.ca/Buffalo-Vacation-Rentals.d717.Travel-Guide-VacationRentals)[East Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-East-Seneca.d553248635975848496.Car-Rental-Guide)[East Seneca Vacations](https://expedia.ca/East-Seneca.d553248635975848496.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in East Seneca, Buffalo from CA $134 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on East Seneca 5 Star Hotels Tonight [Dec 30 - Dec 31](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-12-30&endDate=2025-12-31&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 31 - Jan 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-12-31&endDate=2026-01-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2026-01-02&endDate=2026-01-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for East Seneca 5-star hotels ![2 bars/lounges](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/1b8dbb7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot springs](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/65405b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/727bae68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/ae3eb39b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Curtiss Hotel, an Ascend Collection Hotel [](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) Downtown Buffalo 9.2/10 Wonderful (1006) "Beautiful hotel, beautiful room, outside hot tub and excellent restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) valerie CA $284 CA $332 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-East-Seneca-Buffalo-Hotels.s50-n553248635975848496-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-East-Seneca-Buffalo-Hotels.s50-n553248635975848496-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in East Seneca. ![The Delavan Hotel & Spa](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/c468db44_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Delavan Hotel & Spa 6461 Transit Road Bowmansville NY CA $162 CA $184 total Jan 18 - Jan 19, 2026 includes taxes & fees 8.8/10 Excellent! (1,003 reviews) [](https://expedia.ca/Buffalo-Hotels-The-Delavan-Hotel-Spa.h15031117.Hotel-Information) ![The Mansion On Delaware Ave](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Mansion On Delaware Ave 414 Delaware Ave Buffalo NY CA $223 CA $256 total Jan 28 - Jan 29, 2026 includes taxes & fees 9.4/10 Exceptional! (1,001 reviews) [](https://expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) ![DoubleTree by Hilton Hotel Buffalo - Amherst](https://images.trvl-media.com/lodging/1000000/10000/3000/2914/e3e45ea5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### DoubleTree by Hilton Hotel Buffalo - Amherst 10 Flint Rd Buffalo NY CA $118 CA $134 total Jan 20 - Jan 21, 2026 includes taxes & fees 7.6/10 Good! (1,000 reviews) [](https://expedia.ca/Buffalo-Hotels-DoubleTree-By-Hilton-Hotel-Buffalo-Amherst.h2914.Hotel-Information) Still don't see what you're looking for? [See all properties in East Seneca.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=553248635975848496&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=553248635975848496&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=553248635975848496&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=553248635975848496&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=553248635975848496&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=553248635975848496&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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