Title: 5 Stars Hotels in Downtown Panama City, Panama City - Find Cheap Downtown Panama City Hotels With 5 Stars | Expedia.ca [Downtown Panama City Travel Guide](https://expedia.ca/Panama-City-Downtown-Panama-City.dx906090850344448000)[Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d6023330.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d6023330.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d6023330.Travel-Guide-Activities)[Downtown Panama City Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-Panama-City.d906090850344448000.Car-Rental-Guide)[Downtown Panama City Vacations](https://expedia.ca/Downtown-Panama-City.d906090850344448000.Destination-Travel-Guides) ![Panama City featuring a sandy beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/107000/107496-Panama-City.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Downtown Panama City, Panama City ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown Panama City 5 Star Hotels Tonight [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=906090850344448000&startDate=2025-10-17&endDate=2025-10-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=906090850344448000&startDate=2025-10-18&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=906090850344448000&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=906090850344448000&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown Panama City 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Downtown-Panama-City-Panama-City-Hotels.s50-n906090850344448000-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Downtown-Panama-City-Panama-City-Hotels.s50-n906090850344448000-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown Panama City. ![Bluegreen's Bayside Resort and Spa](https://images.trvl-media.com/lodging/90000000/89720000/89713400/89713340/a74a38e5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Bluegreen's Bayside Resort and Spa 4114 Jan Cooley Dr, Panama City Beach, FL [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F11%2F2025&endDate=02%2F11%2F2025&selected=89713340&PinnedHotelID=89713340&HadPinnedHotel=true®ionId=906090850344448000) 7/10 Good! (306 reviews) [](https://expedia.ca/Panama-City-Beach-Hotels-Bluegreens-Bayside-Resort-And-Spa.h89713340.Hotel-Information) ![Margaritaville Beach Cottage Resort PCB](https://images.trvl-media.com/lodging/102000000/101410000/101406500/101406482/39d3e901_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Beach Cottage Resort PCB 101 Banana Wind Way, Panama City Beach, FL [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F11%2F2025&endDate=02%2F11%2F2025&selected=101406482&PinnedHotelID=101406482&HadPinnedHotel=true®ionId=906090850344448000) 9.8/10 Exceptional! (8 reviews) [](https://expedia.ca/Panama-City-Beach-Hotels-Margaritaville-Beach-Cottage-Resort-PCB.h101406482.Hotel-Information) ![Edgewater Beach and Golf Resort by Southern Vacation Rentals](https://images.trvl-media.com/lodging/1000000/810000/803300/803238/3637fea3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Edgewater Beach and Golf Resort by Southern Vacation Rentals 11211 Front Beach Road, Panama City Beach, FL [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F11%2F2025&endDate=02%2F11%2F2025&selected=803238&PinnedHotelID=803238&HadPinnedHotel=true®ionId=906090850344448000) 7.2/10 Good! (2,201 reviews) [](https://expedia.ca/Panama-City-Hotels-Edgewater-Beach-And-Golf-Resort-By-Resort-Collection.h803238.Hotel-Information) Still don't see what you're looking for? [See all properties in Downtown Panama City.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=906090850344448000&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=906090850344448000&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=906090850344448000&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=906090850344448000&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=906090850344448000&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F10%2F2025&endDate=20%2F10%2F2025®ionId=906090850344448000&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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