Title: 4 Stars Hotels in Upstate South Carolina, South Carolina from CA $144 - Find Cheap Upstate South Carolina Hotels With 4 Stars | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina 4 Star Hotels Tonight [Mar 24 - Mar 25](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2026-03-24&endDate=2026-03-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 25 - Mar 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2026-03-25&endDate=2026-03-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina 4-star hotels ![Exterior](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/a7016c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (465 reviews) "This hotel never disappoints, we had a wonderful and the staff was attentive and very welcoming." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melanie CA $397 CA $448 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/4bf90c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (682 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Helen CA $208 CA $275 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (772 reviews) "Excellent stay, I highly recommend! Accommodations, location, overall vibe, great food and drinks! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $616 CA $684 total includes taxes & fees Apr 24 - Apr 25 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/3786343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/21618793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/fb93f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville Downtown by Kasa [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (804 reviews) "Great location! It was clean, comfortable and quiet! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shannon CA $130 CA $144 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/a0f70343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/93cc35df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville [](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1,002 reviews) "Great hotel Great location Great room Friendly and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $246 CA $270 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/5d8afb5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/6a340cc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/158027e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/6ae08031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Marriott [](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information) Greenville 8.6/10 Excellent (633 reviews) "The airport shuttle arrived within 10 minutes of dispatch and the hotel and restaurant staff were very friendly and accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $156 CA $178 total includes taxes & fees Apr 3 - Apr 4 [](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (578 reviews) "Great staff who demonstrates true southern hospitality. Five minute walk to campus and 10 minutes to downtown - could not be me more convenient. Also cozy bar allowed us to relax after a long day on the road. Nice to see them hiring Clemson students as my daughter who was there for a college tour got some great insights on life at Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Walter [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/fa38c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels [](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Travelers Rest 10/10 Exceptional (18 reviews) "great place perfect for more privacy vs. a standard hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $276 CA $417 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/b8d82b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (33 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck CA $575 CA $633 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/125000000/124260000/124255300/124255207/fa902843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/125000000/124260000/124255300/124255207/c17d158c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/125000000/124260000/124255300/124255207/4b7f96af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Private kitchen](https://images.trvl-media.com/lodging/125000000/124260000/124255300/124255207/93ea82a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Landing Apartments Greer - Sugar Creek [](https://www.expedia.ca/Greer-Hotels-Landing-Stunning-1bd.h124255207.Hotel-Information) Greer [](https://www.expedia.ca/Greer-Hotels-Landing-Stunning-1bd.h124255207.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/8d8778c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/099a6462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/00f3abbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/a549cea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxe Keowee Key Living: Golf Views & Resort Pool [](https://www.expedia.ca/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) ![Apartment, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/c1ffc683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/b51157db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/6a920723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/39a13760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Place Apartments by Landing [](https://www.expedia.ca/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) Greenville 7.6/10 Good (46 reviews) "Loved the apartment! Very spacious, clean, brand new. Access to bike paths. Seemed like a quirky location but everything is close by car or bike. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathie [](https://www.expedia.ca/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/6608ac97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/642f30df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/580b23a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/896f48be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo: Resort Pools & Lake Access! [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) Salem 10/10 Exceptional (1 review) [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/5525119f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/f3e42928.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d3e3f6c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d726d506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Balcony: Lake Keowee Home w/ Pool Access [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/1a03e1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/3d5f6f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/9c5ca6a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/bdf8c3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Views, Pools & Marina: Lake Keowee Condo! [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/5314fa58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/65c7b260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/8692c837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! [](https://www.expedia.ca/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Salem 10/10 Exceptional (1 review) "Property is in a great community, and it was very clean and beautifully decorated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/fa41c5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/be9143a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f8d4e496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f1051c24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 5 Mi to Memorial Stadium & Beach: Modern Townhome [](https://www.expedia.ca/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) Central [](https://www.expedia.ca/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/d429a622.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/c6c3d8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/7e1238ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/fe776675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Steps to Lake Greenwood: Waterfront Gem w/ Patio [](https://www.expedia.ca/Greenwood-Hotels-Steps-To-Lake-Greenwood-Waterfront-Gem-W-Patio.h115993513.Hotel-Information) Greenwood 10/10 Exceptional (2 reviews) "Me and my family really enjoyed the property the view. Everything was nice. We really enjoyed it. Hopefully, we’ll be coming back soon." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luetrina [](https://www.expedia.ca/Greenwood-Hotels-Steps-To-Lake-Greenwood-Waterfront-Gem-W-Patio.h115993513.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/4fa0f099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/8810e390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/fac876d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/cd2123cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salem Vacation Rental w/ Lake Keowee Access! [](https://www.expedia.ca/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/fb4662cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/81a18f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/9f6b4e3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/2ec7bf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Resort Condo: Waterfront Balcony [](https://www.expedia.ca/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) Salem 10/10 Exceptional (1 review) "Very clean. Amazing amenities. Lake view that takes your breath away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany [](https://www.expedia.ca/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels) ## Learn more about Upstate South Carolina Venture to sights like Heritage Park and Conestee Nature Preserve as you discover Upstate South Carolina. [See all hotels in Upstate South Carolina](https://www.expedia.ca/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08&adults=2®ionId=553248635975748552) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) Photo by Ryan Watts ## Top Upstate South Carolina Hotel Reviews ![Mint House Greenville Downtown by Kasa](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb_y.jpg) ### Mint House Greenville Downtown by Kasa 8/10 Good "The coffee machine did not work. Also, for those traveling with family/children it should noted only one TV is available for the property (no tv in the bedrooms)." [](https://expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d_y.jpg) ### Hotel Hartness 10/10 Excellent "Absolutely beautiful property. Dinner at Patterson was phenomenal. Felt like you were in the wine country in California. We were very impressed " [](https://expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent " Yes, very" [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Loved our time here! Staff was super sweet and helpful. Room was very nice and the bed very cozy. Room felt a little small but the bathroom was larger than expected, and again all nice and clean. No complaints! Great place to stay when in the area! Love the mission to help those differently abled, as well!!" [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ## Find out more about Upstate South Carolina If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Upstate South Carolina are calling your name. Known for providing first-rate service in amazing locations, each of the Upstate South Carolina 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Upstate South Carolina. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Upstate South Carolina, South Carolina, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Upstate South Carolina hotels with 4 Stars provide everything you need to unwind in style. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Belvedere ](https://www.expedia.ca/3Star-Belvedere-Hotels.s30-0-d553248634999443381.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Blacksburg ](https://www.expedia.ca/3Star-Blacksburg-Hotels.s30-0-d183936.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Greenville ](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Highland ](https://www.expedia.ca/3Star-Highland-Hotels.s30-0-d553248635975852355.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Ninety Six ](https://www.expedia.ca/3Star-Ninety-Six-Hotels.s30-0-d6348007.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Saluda ](https://www.expedia.ca/4Star-Saluda-Hotels.s40-0-d3000456071.Travel-Guide-Filter-Hotels) - 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