Title: 4 Stars Hotels in Upstate South Carolina, South Carolina from CA $188 - Find Cheap Upstate South Carolina Hotels With 4 Stars | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Upstate South Carolina, South Carolina from CA $188 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina 4 Star Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-15&endDate=2025-10-16&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-16&endDate=2025-10-17&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina 4 Star Hotels ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/dd539dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/924dd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (392) "Very expensive but great location. " CA $406 CA $459 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Superior Room, 2 Queen Beds](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/ee0e0eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson Clemson 9.8/10 Exceptional (704) "Very nice hotel, great staff" CA $265 CA $295 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/a0f70343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/02c3589b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville Greenville Downtown 9.2/10 Wonderful (1004) "Very courteous and helpful staff " CA $279 CA $307 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Two Bedroom Suite](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a4b477d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/18a2116d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a1a743d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Three Bedroom Suite | Private kitchen](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/6315cb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville - Downtown Greenville Downtown 9.2/10 Wonderful (747) "Clean rooms great location " CA $180 CA $204 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d57fd5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (601) "Wonderful boutique hotel!!" CA $225 CA $295 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/9b7f0f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/9207bf75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/6ae08031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/11616a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Marriott Greenville 8.6/10 Excellent (597) "we enjoyed the bar" CA $171 CA $188 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson Clemson 9.6/10 Exceptional (546) "Great place for visiting the university " CA $201 CA $223 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Apartment, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/39a13760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/6a920723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/689c7682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/7d816d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Place Apartments by Landing Greenville 7.8/10 Good (40) "This was false advertising. Property name is not the same and their app did not work and we could not get into the property NOR get anyone on the phone. We spent 2 hours on the phone to try and get in and finally had to book another hotel. And it’s been a week and my money has yet to be returned even though Expedia said they would refund me " [](https://www.expedia.ca/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/2f99255c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![ADA Vista Wedge Cottage](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/38cc695c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels Travelers Rest 10/10 Exceptional (12) "Great place" CA $267 CA $410 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/8c83b96e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a75f160d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a42189bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast Pendleton 10/10 Exceptional (74) "Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! " CA $163 CA $252 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/4694c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique Travelers Rest 9.6/10 Exceptional (30) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." CA $616 CA $678 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/ed9aaf39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/5d51f2ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Private kitchen](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/1d672e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Living room](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/9fa04f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 228 Lakeland Anderson [](https://www.expedia.ca/Anderson-Hotels-228-Lakeland.h111438806.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels) ## Learn more about Upstate South Carolina Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina. [See all hotels in Upstate South Carolina](https://www.expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30&adults=2®ionId=553248635975748552) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by South Carolina Department of Parks, Recreation & Tourism ## Top Upstate South Carolina Hotel Reviews ![Grand Bohemian Lodge Greenville, Autograph Collection](//images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "We celebrated our 36th anniversary; we did not share that with the hotel. We had a wonderful day, enjoyed a welcome complimentary fall drink before heading over the bridge to Jianna's for a wonderful meal. Came back to a comfy bed with a fluffy comforter. We did not stay for coffee, which would have been nice, but we had a nice stay." [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ## Find out more about Upstate South Carolina If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Upstate South Carolina are calling your name. Known for providing first-rate service in amazing locations, each of the Upstate South Carolina 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Upstate South Carolina. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Upstate South Carolina, South Carolina, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Upstate South Carolina hotels with 4 Stars provide everything you need to unwind in style. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Belvedere](https://www.expedia.ca/3Star-Belvedere-Hotels.s30-0-d553248634999443381.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Blacksburg](https://www.expedia.ca/3Star-Blacksburg-Hotels.s30-0-d183936.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Greenville](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Highland](https://www.expedia.ca/3Star-Highland-Hotels.s30-0-d553248635975852355.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Ninety Six](https://www.expedia.ca/3Star-Ninety-Six-Hotels.s30-0-d6348007.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Saluda](https://www.expedia.ca/4Star-Saluda-Hotels.s40-0-d3000456071.Travel-Guide-Filter-Hotels) - 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[Car rentals near 295 Sports Complex](https://www.expedia.ca/Car-Rentals-In-295-Sports-Complex.d6245676.Car-Rental-Guide) - [Rental cars Spartanburg Downtown Memorial airport](https://www.expedia.ca/Car-Rentals-In-Spartanburg-Downtown-Memorial.d6032031.Car-Rental-Guide) - [Book 4 Star Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels)