4 Stars Hotels in Serra Mesa, San Diego from CA $130

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Check availability on Serra Mesa 4 Star Hotels

Top Serra Mesa 4 Star Hotels

Manchester Grand Hyatt San Diego
6 restaurants, breakfast, lunch, dinner served; seafood

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2802)
"We had a great stay here. "
The price is CA $234
CA $346 total
includes taxes & fees
Sep 1 - Sep 2
Manchester Grand Hyatt San Diego
Hyatt Regency Mission Bay Spa and Marina
Exterior

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
8.4 out of 10, Very good, (1498)
"Its a great hotel "
The price is CA $212
CA $311 total
includes taxes & fees
Sep 2 - Sep 3
Hyatt Regency Mission Bay Spa and Marina
Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5858)
"Great location great price. "
The price is CA $209
CA $277 total
includes taxes & fees
Sep 3 - Sep 4
Wyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown
Lobby

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
9.0 out of 10, Wonderful, (1340)
"Great location and breakfast, would stay here again."
The price is CA $244
CA $322 total
includes taxes & fees
Aug 17 - Aug 18
Embassy Suites by Hilton San Diego Bay Downtown
Sheraton Mission Valley San Diego Hotel
Outdoor pool

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.6 out of 10, Excellent, (1476)
"Great Hotel"
The price is CA $175
CA $201 total
includes taxes & fees
Aug 31 - Sep 1
Sheraton Mission Valley San Diego Hotel
Paradise Point Resort & Spa
Property grounds

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2217)
"Its amazing place for vacation "
The price is CA $281
CA $393 total
includes taxes & fees
Aug 24 - Aug 25
Paradise Point Resort & Spa
Sheraton San Diego Resort
Room, 1 King Bed with Sofa bed, Marina View | View from room

Sheraton San Diego Resort

4.0 star property
8.2 out of 10, Very good, (2906)
"Excellent stay.. "
The price is CA $162
CA $244 total
includes taxes & fees
Aug 31 - Sep 1
Sheraton San Diego Resort
San Diego Marriott La Jolla
Outdoor pool

San Diego Marriott La Jolla

4.0 star property
8.6 out of 10, Excellent, (1979)
"Great place to stay "
The price is CA $259
CA $298 total
includes taxes & fees
Aug 15 - Aug 16
San Diego Marriott La Jolla
DoubleTree by Hilton San Diego - Del Mar
Courtyard

DoubleTree by Hilton San Diego - Del Mar

4.0 star property
8.0 out of 10, Very good, (1386)
"Great stay."
The price is CA $181
CA $206 total
includes taxes & fees
Sep 7 - Sep 8
DoubleTree by Hilton San Diego - Del Mar
The Little Italy Hotel Downtown San Diego
View from room

The Little Italy Hotel Downtown San Diego

4.0 star property
8.0 out of 10, Very good, (1023)
"Great stay"
The price is CA $162
CA $188 total
includes taxes & fees
Sep 1 - Sep 2
The Little Italy Hotel Downtown San Diego
Hilton San Diego Bayfront
Outdoor pool, sun loungers

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very good, (1650)
"Beautiful stay!"
The price is CA $265
CA $374 total
includes taxes & fees
Aug 14 - Aug 15
Hilton San Diego Bayfront
Marriott Marquis San Diego Marina
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)

Marriott Marquis San Diego Marina

4.0 star property
9.2 out of 10, Wonderful, (1810)
"Great place to stay."
The price is CA $300
CA $409 total
includes taxes & fees
Sep 1 - Sep 2
Marriott Marquis San Diego Marina
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2800)
"Great hotel "
The price is CA $227
CA $326 total
includes taxes & fees
Aug 30 - Aug 31
Hard Rock Hotel San Diego
Embassy Suites by Hilton San Diego La Jolla
Terrace/patio

Embassy Suites by Hilton San Diego La Jolla

4.0 star property
8.8 out of 10, Excellent, (1612)
"Great accommodations. "
The price is CA $236
CA $272 total
includes taxes & fees
Aug 17 - Aug 18
Embassy Suites by Hilton San Diego La Jolla
Hotel del Coronado, Curio Collection by Hilton
Lobby

Hotel del Coronado, Curio Collection by Hilton

4.0 star property
8.0 out of 10, Very good, (1007)
"We enjoyed our time and our room was very nice. "
The price is CA $439
CA $563 total
includes taxes & fees
Sep 7 - Sep 8
Hotel del Coronado, Curio Collection by Hilton
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1012)
"Loved our stay very accommodating "
The price is CA $274
CA $367 total
includes taxes & fees
Sep 1 - Sep 2
Loews Coronado Bay Resort
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1613)
"Great place!"
The price is CA $130
CA $150 total
includes taxes & fees
Aug 27 - Aug 28
Palihotel San Diego Gaslamp Quarter
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2867)
"Great stay"
The price is CA $211
CA $243 total
includes taxes & fees
Sep 5 - Sep 6
Legacy Resort Hotel & Spa
Town and Country San Diego
2 outdoor pools, a heated pool, cabanas (surcharge), sun loungers

Town and Country San Diego

4.0 star property
8.6 out of 10, Excellent, (1249)
"this is really nice family hotel"
The price is CA $234
CA $317 total
includes taxes & fees
Aug 13 - Aug 14
Town and Country San Diego
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Terrace/patio

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (1012)
"Nice places to stay "
The price is CA $164
CA $190 total
includes taxes & fees
Sep 1 - Sep 2
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Serra Mesa.
Pendry San Diego

Pendry San Diego

550 J Street, San Diego, CA
The price is CA $378 per night from Aug 25 to Aug 26
CA $378
CA $508 total
Aug 25 - Aug 26
includes taxes & fees
9.2/10 Wonderful! (1,004 reviews)
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Top Serra Mesa Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Convenient for race "
Claudia 2-night trip
Posted 5 hours ago
Wyndham San Diego Bayside

Frequently asked questions

What are the best 4-star hotels in Serra Mesa?
Enjoy the comfort and quality of San Diego Marriott Mission Valley. This 4-star hotel around Serra Mesa is recommended highly by many Expedia guests and features a terrace and concierge services. Another in-demand property in or close to this neighbourhood is DoubleTree by Hilton Hotel San Diego - Mission Valley. Concierge services and a terrace are two amenities that help make it popular.
How much does it cost to stay in a 4-star hotel in Serra Mesa?
To lock in a 4-star hotel in Serra Mesa that's within your budget, use Expedia's filter tool. Browse the available options during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the most budget-friendly stay first.

  • Search for the lowest price from CA $326

What's the difference between 5-star and 4-star hotels in Serra Mesa?
Offering an inviting guest experience and upmarket décor, 4-star hotels are a great option for your Serra Mesa escape. These kinds of accommodations generally feature loads of handy amenities that make it easy to unpack and recharge — think 24-hour room service, pools and gyms. Or get a taste of the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Round-the-clock concierge service, premium toiletries and gourmet dining are typically included at these plush properties.