Title: 4 Stars Hotels in Sanctuary, Sanibel from CA $195 - Find Cheap Sanctuary Hotels With 4 Stars | Expedia.ca [Sanctuary Travel Guide](https://expedia.ca/Sanibel-Sanctuary.dx553248635976469368)[Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Sanctuary.d553248635976469368.Car-Rental-Guide)[Sanctuary Vacations](https://expedia.ca/Sanctuary.d553248635976469368.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Sanctuary, Sanibel from CA $195 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanctuary 4 Star Hotels Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-12&endDate=2025-10-13&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-13&endDate=2025-10-14&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sanctuary 4 Star Hotels ![Exterior](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/b4312f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/0153ec95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/1051a5d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers Fort Myers Beach 9.0/10 Wonderful (1531) "Beautiful property, excellent food and friendly staff." CA $221 CA $317 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/8bfa4af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/e5ddcf4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/a68b2adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Fort Myers at Bell Tower Shops Villas 8.8/10 Excellent (1010) "great location, great staff, clean area" CA $175 CA $195 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![On the beach, white sand, kayaking, motor boating](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/39279b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/89736118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/4914d2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Sanibel Harbour Resort & Spa Punta Rassa 8.4/10 Very good (1009) "The hot tub and pools are great the views are great. " CA $225 CA $286 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/167b1a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 Bedroom Captiva Villa,1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/435d58a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/82b672d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pink Shell Beach Resort and Marina Fort Myers Beach 9.4/10 Exceptional (1091) "We have gone there for 4 years for our anniversary or if we have guests and that's absolutely wonderful . " [](https://www.expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/4aba0d83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Non Smoking, River View (Balcony)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/43311ff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/1175676c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Cape Coral Resort At Marina Village Pelican 9.0/10 Wonderful (1008) "Great space and great location. Staff extremely helpful." CA $200 CA $277 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/20000000/19080000/19071400/19071372/a98efe51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19080000/19071400/19071372/7dbafbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19080000/19071400/19071372/8e1ebb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books, stereo](https://images.trvl-media.com/lodging/20000000/19080000/19071400/19071372/11383728.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SEASIDE 503,Penthouse,Direct beach front 230+reviews.Direct gulf front,pool,bch Mid Island 9.8/10 Exceptional (233) "What a great, nice place close to everything! Will definitely be back for another stay!" [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-SEASIDE.h19071372.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/119000000/118250000/118241800/118241758/53f0000f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, bed sheets](https://images.trvl-media.com/lodging/119000000/118250000/118241800/118241758/c67bf475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118250000/118241800/118241758/7d133745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118250000/118241800/118241758/af9b42ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Landing Fort Myers Forestwood Villas [](https://www.expedia.ca/Fort-Myers-Hotels-The-Fountains-At-Forestwood-Apartments-By-Landing.h118241758.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/33000000/32660000/32655100/32655007/d3db3aad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/33000000/32660000/32655100/32655007/b860c331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/33000000/32660000/32655100/32655007/0f33cbf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/33000000/32660000/32655100/32655007/acf3d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BEAUTIFUL SANIBEL ISLAND CONDO!!! - NEW EVERYTHING -NEW AMENITIES!!! Mid Island 9.8/10 Exceptional (49) "Property was well maintained. Close to beach. Lovely area." [](https://www.expedia.ca/Sanibel-Hotels-BEAUTIFUL-SANIBEL-ISLAND-CONDO-NEW-BEDS-UPDATED-MANY-NEW-AMENITIES.h32655007.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111490000/111488300/111488225/9e849186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111490000/111488300/111488225/42c24c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111490000/111488300/111488225/6da4bb22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/112000000/111490000/111488300/111488225/0bf6cd13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Shell Island Beach Club East End 9.6/10 Exceptional (22) "Beautiful view and beautiful beach!" [](https://www.expedia.ca/Sanibel-Hotels-Shell-Island-Beach-Club-Resort.h111488225.Hotel-Information) ![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/33000000/32510000/32505500/32505408/e9159c7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/33000000/32510000/32505500/32505408/36c75788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/33000000/32510000/32505500/32505408/a2768ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32510000/32505500/32505408/3f991912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sundial Resort - Magnificent Gulf View condo - B402 Mid Island 10/10 Exceptional (130) "Paula is a fantastic host. Very clean and great location" [](https://www.expedia.ca/Sanibel-Hotels-Sundial-Resort-Magnificent-Direct-Gulf-View-Condo-B402.h32505408.Hotel-Information) ![2 bedrooms, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/42000000/41830000/41825600/41825542/41a38c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/42000000/41830000/41825600/41825542/71b43ef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41830000/41825600/41825542/65457068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/42000000/41830000/41825600/41825542/66fa070e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 720 ft to beach, 2 BR 2 BA, Pool, Beach Gear, Deck, BBQ, W/D, sleeps 6. Fort Myers Beach 9.6/10 Exceptional (27) "It was a great place. Wish we had had more time there!" CA $335 CA $679 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-720-Ft-To-Beach.h41825542.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/35000000/34070000/34069600/34069588/f7b2c78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34070000/34069600/34069588/6be94e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34070000/34069600/34069588/fc8c354f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34070000/34069600/34069588/ff58c28e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### \- Southern exposure- gulf access- Canal - heated Pool Hancock 9.4/10 Exceptional (74) "We brought our family here for a week for spring break and had a wonderful stay - would recommend for other families! " [](https://www.expedia.ca/Cape-Coral-Hotels-Rental-Possible-After-Ian-Expo-Sud-Access-To-The-Gulf-Canal-Heated-Swimming-Pool.h34069588.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/34000000/33580000/33573800/33573723/16f34a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33580000/33573800/33573723/c36cee0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33580000/33573800/33573723/685297a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33580000/33573800/33573723/f2cb04af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sundial F401 Penthouse Beachfront with Wrap Around Balcony Mid Island 10/10 Exceptional (103) "The listing for the property, especially the video that accompanied it was very misleading. The video showed lushly landscaped grounds and a beautiful fully functioning pool area. In reality there was construction work going on in the building and multiple buildings, Noise, chain link fences in the parking lots, torn up grounds and the pool, while it looked fine wasn't open to the public. The unit itself was very nice and well appointed and furnished but the grounds and the construction noise... [](https://www.expedia.ca/Sanibel-Hotels-Sundial-Beachfront-With-Wrap-Around-Balcony.h33573723.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34490000/34482100/34482085/a0115cf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/35000000/34490000/34482100/34482085/bac4b90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34490000/34482100/34482085/302b805a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34490000/34482100/34482085/38d44719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa South Palms returns! Gulf-access with Southwest facing pool is back! Pelican 9.8/10 Exceptional (33) "Very easy process from booking, enjoying our stay and checking out. Thanks so much!" [](https://www.expedia.ca/Cape-Coral-Hotels-Villa-South-Palms-Gulf-Access-Canal-Home-With-Southwestern-Pool-Exposure.h34482085.Hotel-Information) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/40000000/39200000/39197200/39197109/w799h599x1y1-aa1ba0e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player](https://images.trvl-media.com/lodging/40000000/39200000/39197200/39197109/w796h599x1y1-77fb05b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/40000000/39200000/39197200/39197109/w799h599x1y1-d300d572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/40000000/39200000/39197200/39197109/w800h599x0y1-8bc83268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Beachfront condo with Gulf View FALL SPECIAL 20% OFF ANY RES TIL 10/31 South Island 9.8/10 Exceptional (24) "This is such an amazing condo. The decor is beautiful and the condo is very clean, quiet and welcoming. It feels like home. The beach access is incredible. Views from the enclosed terrace are spectacular. I highly recommend staying here. I can't wait to return." [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Beautiful-Beachfront-Condo-With-Gulf-View.h39197109.Hotel-Information) ![House (4 Bedrooms) | Property amenity](https://images.trvl-media.com/lodging/94000000/93220000/93216900/93216877/f9e9ad43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Property amenity](https://images.trvl-media.com/lodging/94000000/93220000/93216900/93216877/24292a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Property amenity](https://images.trvl-media.com/lodging/94000000/93220000/93216900/93216877/0d6c93a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Property amenity](https://images.trvl-media.com/lodging/94000000/93220000/93216900/93216877/5dca256b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coastal Cozy Villa Caloosahatchee 10/10 Exceptional (2) "The pool was great and the shower in the master bathroom was very nice too" [](https://www.expedia.ca/Cape-Coral-Hotels-Coastal-Cozy-Villa.h93216877.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/34000000/33100000/33092600/33092527/w799h599x1y1-5fda7ae8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33100000/33092600/33092527/45eaf992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33100000/33092600/33092527/a999608e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33100000/33092600/33092527/w799h599x1y1-d00439c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Big & Beautiful 3 BR/ 2 BA + Den ~Wifi, Pool & Sailboat Access Pelican 9.8/10 Exceptional (33) "We enjoyed our stay! Quiet neighborhood. Friendly service." [](https://www.expedia.ca/Cape-Coral-Hotels-Big-Beautiful-3-BR-2-BA-Den-Wifi.h33092527.Hotel-Information) ![Condo, Multiple Beds, Balcony (803 - No Pets Allowed) | Property grounds](https://images.trvl-media.com/lodging/95000000/94910000/94908200/94908193/449923ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo (3 Bedrooms) | Property amenity](https://images.trvl-media.com/lodging/95000000/94910000/94908200/94908193/1c184767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, Multiple Beds, Balcony (803 - No Pets Allowed) | Living area](https://images.trvl-media.com/lodging/95000000/94910000/94908200/94908193/fb40f4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo (3 Bedrooms) | Property amenity](https://images.trvl-media.com/lodging/95000000/94910000/94908200/94908193/50386c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gullwing by VTrips South Island 8.0/10 Very good (2) "Relaxing stay" [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Gullwing-II.h94908193.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/35000000/34060000/34057700/34057664/d4ce3e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/35000000/34060000/34057700/34057664/f23e9270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34060000/34057700/34057664/b0db80d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/35000000/34060000/34057700/34057664/8d30bb08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Sanibel Shell - Luxury villa with pool and access to the Gulf of Mexico Caloosahatchee 9.6/10 Exceptional (37) "Nice house. Clean. Would stay again." [](https://www.expedia.ca/Cape-Coral-Hotels-Villa-Sanibel-Shell-Luxury-Villa-With-Pool-And-Access-To-The-Gulf-Of-Mexico.h34057664.Hotel-Information) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/41000000/40140000/40133600/40133553/2c400ffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/41000000/40140000/40133600/40133553/e510ecdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/41000000/40140000/40133600/40133553/f0e9d0d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/41000000/40140000/40133600/40133553/1dc13862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Tranquilo Bungalow 150 steps to beach, Beach to Bay street. Dog Friendly ! Mid Island 9.8/10 Exceptional (14) "The unit was exactly as described. Very clean, well equipped and in a great location. The bikes, wagons, beach chairs and beach umbrellas were exactly what we needed. Also very close to Publix. It was the perfect size for 2 adults. The backyard was a bonus! We’ll definitely be back!" [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Casa-Tranquilo-Bungalow-150-Steps-To-Beach.h40133553.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Sanctuary-Sanibel-Hotels.s40-n553248635976469368-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Sanctuary-Sanibel-Hotels.s40-n553248635976469368-0.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Sanctuary. ![Sundial Beach Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/c6ba33ac_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sundial Beach Resort & Spa 1451 Middle Gulf Drive, Sanibel, FL CA $439 CA $567 total Oct 27 - Oct 28 includes taxes & fees 8.6/10 Excellent! (2,576 reviews) [](https://expedia.ca/Sanibel-Hotels-Sundial-Beach-Resort-Spa.h1939.Hotel-Information) Still don't see what you're looking for? [See all properties in Sanctuary.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Sanctuary Hotel Reviews ![Margaritaville Beach Resort Fort Myers ](//images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg) ### Margaritaville Beach Resort Fort Myers 10/10 Excellent "Excellent stay great customer service in every encounter. Lots to do on site! Will definitely return!" [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](//images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "Great space and great location. Staff extremely helpful." [](https://expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Pink Shell Beach Resort and Marina](//images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Very satisfied with the hotel, amenities and our stay. We will be back! " [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg) ### Marriott Sanibel Harbour Resort & Spa 10/10 Excellent "The time at the pool was amazing. Really nice views from the room" [](https://expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](//images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 10/10 Excellent "/" [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [1 Star Hotels in Villas](https://www.expedia.ca/1Star-Villas-Fort-Myers-Hotels.s10-n553248628384480340-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Burnt Store](https://www.expedia.ca/2Star-Burnt-Store-Cape-Coral-Hotels.s20-n553248635976481229-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Eight Lakes](https://www.expedia.ca/2Star-Eight-Lakes-Cape-Coral-Hotels.s20-n553248635976481277-0.Travel-Guide-Filter-Hotels) - 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