Title: 4 Stars Hotels in Mayo Clinic, Phoenix from CA $183 - Find Cheap Mayo Clinic Hotels With 4 Stars | Expedia.ca [Mayo Clinic Travel Guide](https://expedia.ca/Phoenix-Mayo-Clinic.dx553248635976008216)[Vacation Rentals in Phoenix](https://expedia.ca/Phoenix-Vacation-Rentals.d178298.Travel-Guide-VacationRentals)[Flights to Phoenix](https://expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights)[Things to do in Phoenix](https://expedia.ca/Things-To-Do-In-Phoenix.d178298.Travel-Guide-Activities)[Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d553248635976008216.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic.d553248635976008216.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Mayo Clinic, Phoenix from CA $183 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mayo Clinic 4 Star Hotels Tonight [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-09-29&endDate=2025-09-30&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-09-30&endDate=2025-10-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mayo Clinic 4 Star Hotels ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, rainfall showerhead, designer toiletries, hair dryer](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/e9fa5518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/5b195237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/a0a768b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### FOUNDRE Phoenix Downtown Phoenix 9.2/10 Wonderful (2089) "Very clean and the beds were comfortable" CA $177 CA $238 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/a3647272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/3e53fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/bff92d86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Talking Stick Resort Scottsdale 9.2/10 Wonderful (3916) "Great place to stay! " CA $145 CA $205 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/7dd274ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/86658d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/a6edea6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Tapatio Cliffs Resort North Mountain 8.4/10 Very good (2143) "Nice amenities and rooms, beautiful area " CA $208 CA $296 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/225d2d95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water park](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/58e97f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/149ac95f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/73dca207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arizona Grand Resort & Spa South Mountain 8.6/10 Excellent (2210) "Great stay. " CA $166 CA $314 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Arizona-Grand-Resort-Spa.h2774.Hotel-Information) ![7 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/3011de6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed (Agave Suite)](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/24a59e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/420aa05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/64c30695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Resort at the Peak Camelback East 7.6/10 Good (3195) "Excellent Resort" CA $200 CA $281 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Resort-At-The-Peak.h2729.Hotel-Information) ![3 outdoor pools, open 5:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/38914575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/28aedebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/29947803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; Spanish cuisine](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/457b3c58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Scottsdale Resort & Spa at Montelucia Paradise Hills 9.2/10 Wonderful (1029) "great stay! " CA $403 CA $527 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Omni-Scottsdale-Resort-Spa-At-Montelucia.h2263.Hotel-Information) ![2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/623ec1de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Sleeper Sofa Beds, Non-Smoking | Living area](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/f89b1437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/1f002075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/bcc3143a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree Resort by Hilton Paradise Valley - Scottsdale Scottsdale 8.6/10 Excellent (1170) "Great stay" CA $176 CA $246 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Phoenix-Hotels-DoubleTree-Resort-By-Hilton-Paradise-Valley-Scottsdale.h25521.Hotel-Information) ![Room, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/3450908d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/cde201c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/2e7fc129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/6a36de96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Airport South Mountain 8.8/10 Excellent (1032) "Great hotel and location " CA $162 CA $183 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Airport.h25957.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/dfaa8e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/7450fe46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite (Loft)](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/35036770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/6edb5b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Valley Ho Old Town 9.6/10 Exceptional (1992) "Love this place! Excellent spa, restaurant, room service and soaking tub." CA $304 CA $347 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Hotel-Valley-Ho.h15298.Hotel-Information) ![Rooftop bar, alfresco dining, open select days](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/c2559566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | City view](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/224371c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, alfresco dining, open select days](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/836ca89d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, alfresco dining, open select days](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/e40980de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Tempe Hotel at ASU Tempe 9.4/10 Exceptional (1174) "We loved everything about our stay!" CA $227 CA $299 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Phoenix-Hotels-Omni-Tempe-Hotel-At-Asu.h88188988.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/81eafc4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/8040d9d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/e097c97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; alfresco dining](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/348cc149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kimpton Hotel Palomar Phoenix Cityscape by IHG Downtown Phoenix 9.0/10 Wonderful (1155) "The staff and facilities were excellent. Will definitely stay again. " CA $255 CA $343 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Phoenix-Hotels-Kimpton-Hotel-Palomar-Phoenix-Cityscape.h5052263.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/60dc5918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/d3f0b242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/2c100a78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/bec35d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Phoenix Resort Tempe at The Buttes Tempe 8.6/10 Excellent (1016) "I love staying here. " CA $275 CA $337 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Phoenix-Hotels-Marriott-Phoenix-Resort-Tempe-At-The-Buttes.h82743.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/6000/5983/36ae6f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/6000/5983/d8c6c881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6000/5983/cff2dec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/6000/5983/80235d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Phoenix Downtown Downtown Phoenix 9.0/10 Wonderful (1007) "I loved the restaurante atmosphere" CA $224 CA $289 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Phoenix-Hotels-Renaissance-Phoenix-Downtown.h5983.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/4fb94d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/c8f78ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/1ba200ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/4ca4b17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Phoenix Downtown Phoenix 9.2/10 Wonderful (1840) "I love this hotel clean, comfortable " CA $259 CA $333 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Phoenix-Hotels-Hyatt-Regency-Phoenix.h6802.Hotel-Information) ![Outdoor pool, open 7:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/a4848311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/w3837h2557x0y0-30b08a9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/49aac16a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/fab94181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Phoenix Tempe Tempe 8.4/10 Very good (1092) "Great Stay" CA $164 CA $187 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Phoenix-Hotels-DoubleTree-By-Hilton-Hotel-Phoenix-Tempe.h8679.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/17000000/16720000/16715800/16715713/e7530fd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/17000000/16720000/16715800/16715713/63037651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/17000000/16720000/16715800/16715713/0906af51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/17000000/16720000/16715800/16715713/e687e654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mountain Shadows Resort Scottsdale Paradise Valley 9.8/10 Exceptional (1026) "Great Stay!!!" CA $400 CA $519 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Mountain-Shadows-Resort-Scottsdale.h16715713.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/55000000/54160000/54159600/54159544/cd4fec43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54160000/54159600/54159544/3f2a877f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54160000/54159600/54159544/98406b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/55000000/54160000/54159600/54159544/db7b464f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canopy by Hilton Scottsdale Old Town Old Town 9.6/10 Exceptional (1020) "Amazing stay and staff" CA $336 CA $383 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Phoenix-Hotels-Canopy-By-Hilton-Scottsdale-Old-Town.h54159544.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/w4000h2664x0y0-9226bc87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, alfresco dining, open daily](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/dfea38c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Mountain View](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/5e40c1c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/f46d1810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Tempe Downtown Tempe 9.4/10 Exceptional (948) "Great location. " CA $164 CA $229 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Phoenix-Hotels-The-Westin-Tempe.h60258737.Hotel-Information) ![In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/42000000/41970000/41960700/41960665/a4509d0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/42000000/41970000/41960700/41960665/aa330844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/42000000/41970000/41960700/41960665/303ef637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner served; Mexican cuisine, pool views ](https://images.trvl-media.com/lodging/42000000/41970000/41960700/41960665/8f4218c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rise Uptown Hotel Alhambra 9.2/10 Wonderful (1115) "Very cool property, nice chill vibe and everyone’s so friendly. Rooms are large, love the decor and location is great. Would 100% stay here again, pool and bar are amazing!" CA $138 CA $202 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-ARRIVE-Phoenix.h41960665.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/300/240/589d5d86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/1000000/10000/300/240/6db5edb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/300/240/1d09403c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/300/240/21205ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottsdale Plaza Resort Paradise Valley 8.8/10 Excellent (2238) "Great stay highly recommended " CA $177 CA $261 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Phoenix-Hotels-Scottsdale-Plaza-Resort.h240.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mayo-Clinic-Phoenix-Hotels.s40-n553248635976008216-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mayo-Clinic-Phoenix-Hotels.s40-n553248635976008216-0.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mayo Clinic. ![Arizona Biltmore, LXR Hotels & Resorts](https://images.trvl-media.com/lodging/1000000/10000/9800/9796/e16a0f80_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arizona Biltmore, LXR Hotels & Resorts 2400 E Missouri Avenue, Phoenix, AZ CA $556 CA $711 total Oct 30 - Oct 31 includes taxes & fees 9/10 Wonderful! (1,025 reviews) [](https://expedia.ca/Phoenix-Hotels-Arizona-Biltmore.h9796.Hotel-Information) ![The Phoenician, a Luxury Collection Resort, Scottsdale](https://images.trvl-media.com/lodging/1000000/20000/10700/10645/bfaa47ae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Phoenician, a Luxury Collection Resort, Scottsdale 6000 E Camelback Rd, Paradise Valley, AZ CA $859 CA $1,050 total Oct 30 - Oct 31 includes taxes & fees 9/10 Wonderful! (1,000 reviews) [](https://expedia.ca/Phoenix-Hotels-The-Phoenician.h10645.Hotel-Information) ![JW Marriott Phoenix Desert Ridge Resort & Spa](https://images.trvl-media.com/lodging/1000000/900000/892800/892733/6b827d46_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### JW Marriott Phoenix Desert Ridge Resort & Spa 5350 E Marriott Dr, Phoenix, AZ CA $563 CA $723 total Oct 30 - Oct 31 includes taxes & fees 9/10 Wonderful! (1,013 reviews) [](https://expedia.ca/Phoenix-Hotels-JW-Marriott-Phoenix-Desert-Ridge-Resort-Spa.h892733.Hotel-Information) Still don't see what you're looking for? [See all properties in Mayo Clinic.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=553248635976008216&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=553248635976008216&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=553248635976008216&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=553248635976008216&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=553248635976008216&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=553248635976008216&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Mayo Clinic Hotel Reviews ![FOUNDRE Phoenix](//images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0_y.jpg) ### FOUNDRE Phoenix 10/10 Excellent "Very clean and the beds were comfortable" [](https://expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information) ![Hilton Phoenix Airport](//images.trvl-media.com/lodging/1000000/30000/26000/25957/3450908d_y.jpg) ### Hilton Phoenix Airport 10/10 Excellent "Loved it" [](https://expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Airport.h25957.Hotel-Information) ![Arizona Grand Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/2800/2774/225d2d95_y.jpg) ### Arizona Grand Resort & Spa 10/10 Excellent "It really gives you a luxurious feel! The dining is epic! Waterpark is epic! Although, some of the hot tubs didn’t work, which was weird" [](https://expedia.ca/Phoenix-Hotels-Arizona-Grand-Resort-Spa.h2774.Hotel-Information) ![Hyatt Regency Phoenix](//images.trvl-media.com/lodging/1000000/10000/6900/6802/4fb94d6b_y.jpg) ### Hyatt Regency Phoenix 10/10 Excellent "Room was clean.all of our expectations met.thank you" [](https://expedia.ca/Phoenix-Hotels-Hyatt-Regency-Phoenix.h6802.Hotel-Information) ![Talking Stick Resort](//images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841_y.jpg) ### Talking Stick Resort 10/10 Excellent "loved it" [](https://expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Hilton Phoenix Tapatio Cliffs Resort](//images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6_y.jpg) ### Hilton Phoenix Tapatio Cliffs Resort 10/10 Excellent "Our room was amazing and HUGE overlooking the beautiful waterfalls and grounds... the staff was so kind and friendly. BTW please give MARC at the pool service, he was AMAZING and so genuine.... Loved this place and we're moving here because of the Cliffs!" [](https://expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information) ![DoubleTree by Hilton Phoenix Tempe](//images.trvl-media.com/lodging/1000000/10000/8700/8679/a4848311_y.jpg) ### DoubleTree by Hilton Phoenix Tempe 10/10 Excellent "We stayed her before we left on a trip, was able for a reasonable rate to part our car while we were gone and then pick up our car at end of trip. What a convenience. The restaurant/bar was also great to enjoy before and after our trip. " [](https://expedia.ca/Phoenix-Hotels-DoubleTree-By-Hilton-Hotel-Phoenix-Tempe.h8679.Hotel-Information) ![DoubleTree Resort by Hilton Paradise Valley - Scottsdale](//images.trvl-media.com/lodging/1000000/30000/25600/25521/623ec1de_y.jpg) ### DoubleTree Resort by Hilton Paradise Valley - Scottsdale 10/10 Excellent "All good" [](https://expedia.ca/Phoenix-Hotels-DoubleTree-Resort-By-Hilton-Paradise-Valley-Scottsdale.h25521.Hotel-Information) ![Hilton Phoenix Resort at the Peak](//images.trvl-media.com/lodging/1000000/10000/2800/2729/fabaa98e_y.jpg) ### Hilton Phoenix Resort at the Peak 10/10 Excellent "Great pools and semi water park. Nice big rooms too. Lots of construction right now and water park area closes at 6pm. Wish they had more food options, good food options " [](https://expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Resort-At-The-Peak.h2729.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Woodland Springs](https://www.expedia.ca/1Star-Woodland-Springs-Phoenix-Hotels.s10-n553248635976473932-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Lone Mountain Ranch](https://www.expedia.ca/2Star-Lone-Mountain-Ranch-Phoenix-Hotels.s20-n553248635976477147-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Mesa Madrid](https://www.expedia.ca/2Star-Mesa-Madrid-Phoenix-Hotels.s20-n553248635976470476-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Sundown Ranch Estates](https://www.expedia.ca/2Star-Sundown-Ranch-Estates-Phoenix-Hotels.s20-n553248635976477187-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Arcadia Lite](https://www.expedia.ca/3Star-Arcadia-Lite-Phoenix-Hotels.s30-n553248635976471215-0.Travel-Guide-Filter-Hotels) - 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