Title: 4 Stars Hotels in Mayo Clinic, Phoenix from CA $128 - Find Cheap Mayo Clinic Hotels With 4 Stars | Expedia.ca [Mayo Clinic Travel Guide](https://expedia.ca/Phoenix-Mayo-Clinic.dx553248635976008216)[Vacation Rentals in Phoenix](https://expedia.ca/Phoenix-Vacation-Rentals.d178298.Travel-Guide-VacationRentals)[Flights to Phoenix](https://expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights)[Things to do in Phoenix](https://expedia.ca/Things-To-Do-In-Phoenix.d178298.Travel-Guide-Activities)[Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d553248635976008216.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic.d553248635976008216.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Mayo Clinic, Phoenix from CA $128 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mayo Clinic 4 Star Hotels Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-31&endDate=2025-11-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-01&endDate=2025-11-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mayo Clinic 4 Star Hotels ![Exterior](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/a3647272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/bff92d86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/3e53fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Talking Stick Resort Scottsdale 9.2/10 Wonderful (4038) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth CA $225 CA $296 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/9cb71336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, rainfall showerhead, designer toiletries, hair dryer](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/e9fa5518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/a0a768b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### FOUNDRE Phoenix Downtown Phoenix 9.0/10 Wonderful (2146) "Really great option" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) YOLANDA CA $179 CA $240 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information) ![3 outdoor pools, open 5:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/38914575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/d126ceef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/28aedebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; Spanish cuisine](https://images.trvl-media.com/lodging/1000000/10000/2300/2263/457b3c58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Scottsdale Resort & Spa at Montelucia Paradise Hills 9.2/10 Wonderful (1003) "great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caroline CA $301 CA $412 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Phoenix-Hotels-Omni-Scottsdale-Resort-Spa-At-Montelucia.h2263.Hotel-Information) ![2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/623ec1de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, open select days](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/1f002075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/bcc3143a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Sleeper Sofa Beds, Non-Smoking | Living area](https://images.trvl-media.com/lodging/1000000/30000/25600/25521/f89b1437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree Resort by Hilton Paradise Valley - Scottsdale Scottsdale 8.6/10 Excellent (1259) "We enjoyed our stay. Very clean hotel with friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $159 CA $228 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-DoubleTree-Resort-By-Hilton-Paradise-Valley-Scottsdale.h25521.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/4fb94d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/1ba200ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/0f659cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/4ca4b17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Phoenix Downtown Phoenix 9.2/10 Wonderful (1860) "Nice place good staff and enjoyable stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane CA $201 CA $266 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Phoenix-Hotels-Hyatt-Regency-Phoenix.h6802.Hotel-Information) ![Rooftop bar, alfresco dining, open select days](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/c2559566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, alfresco dining, open select days](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/e40980de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/0ee6b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | City view](https://images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/224371c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Tempe Hotel at ASU Tempe 9.4/10 Exceptional (1211) "We loved everything about our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $150 CA $211 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Phoenix-Hotels-Omni-Tempe-Hotel-At-Asu.h88188988.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/81eafc4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/50498872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; alfresco dining](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/348cc149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5060000/5052300/5052263/e097c97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kimpton Hotel Palomar Phoenix Cityscape by IHG Downtown Phoenix 9.2/10 Wonderful (1173) "Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $189 CA $269 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-Kimpton-Hotel-Palomar-Phoenix-Cityscape.h5052263.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/dfaa8e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/6edb5b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite (Loft)](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/eb4a3aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/96a2fd61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Valley Ho Old Town 9.6/10 Exceptional (2070) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kendal CA $322 CA $367 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-Hotel-Valley-Ho.h15298.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/225d2d95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/73dca207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water park](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/58e97f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/2800/2774/149ac95f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arizona Grand Resort & Spa South Mountain 8.6/10 Excellent (2251) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward P CA $180 CA $330 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Phoenix-Hotels-Arizona-Grand-Resort-Spa.h2774.Hotel-Information) ![Outdoor pool, open 7:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/a4848311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/fab94181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/w3837h2557x0y0-30b08a9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/8700/8679/49aac16a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Phoenix Tempe Tempe 8.4/10 Very good (1125) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy CA $125 CA $142 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Phoenix-Hotels-DoubleTree-By-Hilton-Hotel-Phoenix-Tempe.h8679.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/11600/11548/188297f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11548/de978444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/20000/11600/11548/9c50f61a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/20000/11600/11548/93f76107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree Suites by Hilton Phoenix Camelback East 8.2/10 Very good (1630) "A perfect hotel for a night between flights. Excellent shuttle service between airport and hotel. Food was good and staff very helpful." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Mary CA $114 CA $128 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-DoubleTree-Suites-By-Hilton-Phoenix.h11548.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/60dc5918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/bec35d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/2c100a78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/efed6747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Phoenix Resort Tempe at The Buttes Tempe 8.6/10 Excellent (1026) "Loved every part of my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $225 CA $281 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Phoenix-Hotels-Marriott-Phoenix-Resort-Tempe-At-The-Buttes.h82743.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/bd5c95c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/7dd274ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/a6edea6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Tapatio Cliffs Resort North Mountain 8.6/10 Excellent (2164) "Very pleasant place, it was beautiful! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miryam CA $148 CA $228 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information) ![7 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/3011de6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/64c30695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/420aa05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed (Agave Suite)](https://images.trvl-media.com/lodging/1000000/10000/2800/2729/24a59e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Resort at the Peak Camelback East 7.6/10 Good (3183) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) keisha CA $178 CA $256 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Resort-At-The-Peak.h2729.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/49000000/48530000/48527400/48527359/9124ec9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48530000/48527400/48527359/b9c24ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/49000000/48530000/48527400/48527359/05b6283a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/49000000/48530000/48527400/48527359/bd443b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canopy by Hilton Tempe Downtown Downtown Tempe 9.4/10 Exceptional (1005) "Loved our stay there.... would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robyn CA $148 CA $169 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-Canopy-By-Hilton-Tempe-Downtown.h48527359.Hotel-Information) ![Room, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/3450908d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/cde201c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/2e7fc129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/142012c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Airport South Mountain 8.8/10 Excellent (1054) "Had a good experience. Will stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $132 CA $149 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Airport.h25957.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7900/7862/b01ba428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7900/7862/b7f1a006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/7900/7862/0253fe2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/10000/7900/7862/8d73111f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Scottsdale Resort & Villas Scottsdale 8.2/10 Very good (1007) "Enjoyed my time there" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $211 CA $288 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Scottsdale-Resort-Villas.h7862.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/10000/2700/2615/7382abe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/2700/2615/3ab167c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2700/2615/aa1f0c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/2700/2615/a441ff01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Adeline, Scottsdale, a Tribute Portfolio Hotel Scottsdale 8.6/10 Excellent (1001) "Love this place! The staff was wonderful, great pool, fun for families and large groups. We had a mini family reunion all staying at the hotel. It was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $182 CA $247 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Phoenix-Hotels-Hotel-Adeline.h2615.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/w4000h2664x0y0-9226bc87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/72f7ece2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, alfresco dining, open daily](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/dfea38c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/f46d1810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Tempe Downtown Tempe 9.4/10 Exceptional (988) "clean room and nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelci CA $169 CA $235 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Phoenix-Hotels-The-Westin-Tempe.h60258737.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1190000/1184200/1184132/1a65e3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio](https://images.trvl-media.com/lodging/2000000/1190000/1184200/1184132/bfa05984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1190000/1184200/1184132/05ff52a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1190000/1184200/1184132/b540f5bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottsdale Camelback Resort Scottsdale 9.0/10 Wonderful (1243) "Great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $133 CA $179 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Phoenix-Hotels-Scottsdale-Camelback-Resort.h1184132.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mayo-Clinic-Phoenix-Hotels.s40-n553248635976008216-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mayo-Clinic-Phoenix-Hotels.s40-n553248635976008216-0.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mayo Clinic. ![Arizona Biltmore, LXR Hotels & Resorts](https://images.trvl-media.com/lodging/1000000/10000/9800/9796/e16a0f80_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arizona Biltmore, LXR Hotels & Resorts 2400 E Missouri Avenue, Phoenix, AZ CA $458 CA $600 total Nov 23 - Nov 24 includes taxes & fees 9/10 Wonderful! (1,017 reviews) [](https://expedia.ca/Phoenix-Hotels-Arizona-Biltmore.h9796.Hotel-Information) ![Boulders Resort & Spa Scottsdale, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/10800/10782/479e93c1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Boulders Resort & Spa Scottsdale, Curio Collection by Hilton 34631 N Tom Darlington Dr, Scottsdale, AZ CA $263 CA $355 total Nov 23 - Nov 24 includes taxes & fees 8.8/10 Excellent! (1,004 reviews) [](https://expedia.ca/Phoenix-Hotels-Boulders-Resort-Spa-Scottsdale.h10782.Hotel-Information) ![The Phoenician, a Luxury Collection Resort, Scottsdale](https://images.trvl-media.com/lodging/1000000/20000/10700/10645/bfaa47ae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Phoenician, a Luxury Collection Resort, Scottsdale 6000 E Camelback Rd, Paradise Valley, AZ CA $663 CA $829 total Nov 23 - Nov 24 includes taxes & fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.ca/Phoenix-Hotels-The-Phoenician.h10645.Hotel-Information) Still don't see what you're looking for? [See all properties in Mayo Clinic.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248635976008216&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248635976008216&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248635976008216&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248635976008216&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248635976008216&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248635976008216&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Mayo Clinic Hotel Reviews ![Omni Scottsdale Resort & Spa at Montelucia](//images.trvl-media.com/lodging/1000000/10000/2300/2263/38914575_y.jpg) ### Omni Scottsdale Resort & Spa at Montelucia 10/10 Excellent "The pool and hot tub were amazing, loved eating at Prado for breakfast every day, the resort was peaceful, the DJ at the pool was a fun surprise. The staff were friendly and helpful and we enjoyed the spa! I am a neat freak and the room was spotless. Literally everything was perfection! We will absolutely be back. " [](https://expedia.ca/Phoenix-Hotels-Omni-Scottsdale-Resort-Spa-At-Montelucia.h2263.Hotel-Information) ![Talking Stick Resort](//images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841_y.jpg) ### Talking Stick Resort 10/10 Excellent "Beautiful rooms and overall property " [](https://expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Arizona Grand Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/2800/2774/225d2d95_y.jpg) ### Arizona Grand Resort & Spa 10/10 Excellent "Great experience " [](https://expedia.ca/Phoenix-Hotels-Arizona-Grand-Resort-Spa.h2774.Hotel-Information) ![Hilton Phoenix Tapatio Cliffs Resort](//images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6_y.jpg) ### Hilton Phoenix Tapatio Cliffs Resort 10/10 Excellent "Great as always. " [](https://expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information) ![FOUNDRE Phoenix](//images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0_y.jpg) ### FOUNDRE Phoenix 10/10 Excellent "VERY CLEAN QUIET GREAT FOOD AND DRINKS AMAZING DSTAFF VALET AND SELF PARK BIG ROOMS VERY COOL AND HIP" [](https://expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information) ![DoubleTree Resort by Hilton Paradise Valley - Scottsdale](//images.trvl-media.com/lodging/1000000/30000/25600/25521/623ec1de_y.jpg) ### DoubleTree Resort by Hilton Paradise Valley - Scottsdale 10/10 Excellent "We stayed 10/22-10/25 for girls trip. Our stay was absolute perfection! They did have some construction going on near the lobby but it didn’t bother us. They gave all guests complimentary drink vouchers for the “trouble”, which was nice. Those sunrise drinks were so delicious!! We ate at the restaurant once for breakfast (we opted for the buffet; the fingerling potatoes were soooo good!), and once for lunch poolside. The fish tacos were freakin yummy!!! And the cucumber spritzer was so refreshing! 10/10 stay. Can’t wait to go back." [](https://expedia.ca/Phoenix-Hotels-DoubleTree-Resort-By-Hilton-Paradise-Valley-Scottsdale.h25521.Hotel-Information) ![Scottsdale Plaza Resort](//images.trvl-media.com/lodging/1000000/10000/300/240/589d5d86_y.jpg) ### Scottsdale Plaza Resort 10/10 Excellent "The place is beautiful, can't wait to see how this place turns out if I give one thing that would make this place better is if they can be a little more courteous to last minute people with the prices kind of an overkill but ill still leave the five stars but amazing place by the way" [](https://expedia.ca/Phoenix-Hotels-Scottsdale-Plaza-Resort.h240.Hotel-Information) ![Omni Tempe Hotel at ASU](//images.trvl-media.com/lodging/89000000/88190000/88189000/88188988/c2559566_y.jpg) ### Omni Tempe Hotel at ASU 10/10 Excellent "We love the Tempe Omni! Convenient to restaurants, bars & ASU. 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[Central Scottsdale Hotels](https://www.expedia.ca/Central-Scottsdale-Phoenix-Hotels.0-n553248635976007832-0.Travel-Guide-Filter-Hotels) - [Desert Orchid Hotels](https://www.expedia.ca/Desert-Orchid-Phoenix-Hotels.0-n553248635976476874-0.Travel-Guide-Filter-Hotels) - [Hotels near Eagle Mountain Golf Course](https://www.expedia.ca/Eagle-Mountain-Golf-Course-Hotels.0-l6158120-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Eagle Mountain](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels-Casino-Hotel.0-n553248635976469219-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Eagle Mountain](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels-Golf-Hotel.0-n553248635976469219-0-tGolfHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Eagle Mountain](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels-Luxury-Hotel.0-n553248635976469219-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Eagle Mountain](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels-Mountain-Hotels.0-n553248635976469219-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Eagle Mountain](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels-Pet-Friendly-Hotel.0-n553248635976469219-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Eagle Mountain](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels-Spa-Hotel.0-n553248635976469219-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Eagle Mountain Hotels](https://www.expedia.ca/Eagle-Mountain-Phoenix-Hotels.0-n553248635976469219-0.Travel-Guide-Filter-Hotels) - [Eagle Ridge North Hotels](https://www.expedia.ca/Eagle-Ridge-North-Phoenix-Hotels.0-n553248635976479026-0.Travel-Guide-Filter-Hotels) - [Firerock Hotels](https://www.expedia.ca/Firerock-Phoenix-Hotels.0-n553248635976480726-0.Travel-Guide-Filter-Hotels) - [Golf Hotels in Fountain Hills](https://www.expedia.ca/Fountain-Hills-Hotels-Golf-Hotel.0-0-d7820-tGolfHotel.Travel-Guide-Filter-Hotels) - [Fountain Hills Hotels](https://www.expedia.ca/Fountain-Hills-Hotels.d7820.Travel-Guide-Hotels) - [Hotels near Mayo Clinic Scottsdale](https://www.expedia.ca/Mayo-Clinic-Scottsdale-Hotels.0-l6131819-0.Travel-Guide-Filter-Hotels) - [Hotels near McDowell Mountain Golf Club](https://www.expedia.ca/McDowell-Mountain-Golf-Club-Hotels.0-l553248621555612402-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in McDowell Ranchos](https://www.expedia.ca/McDowell-Ranchos-Phoenix-Hotels-Cheap-Hotels.0-n553248635976476658-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Independent Hotels in McDowell Ranchos](https://www.expedia.ca/McDowell-Ranchos-Phoenix-Hotels-Independent.0-n553248635976476658-0--bIndependent.Travel-Guide-Filter-Hotels) - [Mirage Mountain Hotels](https://www.expedia.ca/Mirage-Mountain-Phoenix-Hotels.0-n553248635976473432-0.Travel-Guide-Filter-Hotels) - [Scottsdale Foothills Hotels](https://www.expedia.ca/Scottsdale-Foothills-Phoenix-Hotels.0-n553248635976468522-0.Travel-Guide-Filter-Hotels) - [Scottsdale Hotels](https://www.expedia.ca/Scottsdale-Hotels.d9829.Travel-Guide-Hotels) - [Scottsdale Mountain Hotels](https://www.expedia.ca/Scottsdale-Mountain-Phoenix-Hotels.0-n553248635976479297-0.Travel-Guide-Filter-Hotels) - 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[Sonoran Heights Hotels](https://www.expedia.ca/Sonoran-Heights-Phoenix-Hotels.0-n553248635976468498-0.Travel-Guide-Filter-Hotels) - [Stonehaven Hotels](https://www.expedia.ca/Stonehaven-Phoenix-Hotels.0-n553248635976479675-0.Travel-Guide-Filter-Hotels) - [Hotels near SunRidge Canyon Golf Club](https://www.expedia.ca/SunRidge-Canyon-Golf-Club-Hotels.0-l6158124-0.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Town Center](https://www.expedia.ca/Town-Center-Phoenix-Hotels-Beach-Hotel.0-n553248635976481029-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Town Center](https://www.expedia.ca/Town-Center-Phoenix-Hotels-Romantic-Hotel.0-n553248635976481029-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Flights to Fountain Hills](https://www.expedia.ca/Cheap-Flights-To-Fountain-Hills.d7820.Travel-Guide-Flights) - [Flights to Phoenix](https://www.expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights) - [Flights from Toronto (YYZ) to Phoenix (PHX)](https://www.expedia.ca/lp/flights/yyz/phx/toronto-to-phoenix) - [Mayo Clinic Scottsdale](https://www.expedia.ca/Mayo-Clinic-Scottsdale-Central-Scottsdale.d6131819.Vacation-Attraction) - [Visit Mirage Mountain](https://www.expedia.ca/Phoenix-Mirage-Mountain.dx553248635976473432) - [Visit Mountainside Plaza](https://www.expedia.ca/Phoenix-Mountainside-Plaza.dx553248635976480453) - [Visit Sienna Canyon](https://www.expedia.ca/Phoenix-Sienna-Canyon.dx553248635976477067) - [Car rental Fountain Hills](https://www.expedia.ca/Car-Rentals-In-Fountain-Hills.d7820.Car-Rental-Guide) - [Hertz Rental Cars in Fountain Hills](https://www.expedia.ca/Hertz-Car-Rentals-In-Fountain-Hills.d7820-c40.Car-Rental-Guide-Suppliers) - [Fountain Hills Vacation Rentals](https://www.expedia.ca/Fountain-Hills-Vacation-Rentals.d7820.Travel-Guide-VacationRentals) - [Things to do in Fountain Hills](https://www.expedia.ca/Things-To-Do-In-Fountain-Hills.d7820.Travel-Guide-Activities) - [Book Hotels in Mayo Clinic on Expedia.com](https://www.expedia.com/4Star-Mayo-Clinic-Phoenix-Hotels.s40-n553248635976008216-0.Travel-Guide-Filter-Hotels)