4 Stars Hotels in Hannibal, Missouri from CA $311

A river with a bridge, a town, and a forested hillside.

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Our top choices for Hannibal 4-star hotels

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

1. Lighthouse Inn & Suites

Hannibal

Connie

CA $227

CA $311 total

includes taxes & fees

Oct 12 - Oct 13

A large, historic mansion with a grand entrance, multiple windows, and a well-maintained lawn.

A spacious bedroom with a four-poster bed, a large window, and a balcony.

A two-story building with a symmetrical facade, large windows, and a central entrance.

A spiral staircase with ornate wooden balusters and patterned carpet.

2. Garth Woodside Mansion B&B

Hannibal

Tammy

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Hannibal and related destinations

Mark Twain's boyhood home invites you to step into the world that inspired Tom Sawyer and Huckleberry Finn. Explore limestone caves, take a riverboat cruise, or hike to Lover's Leap for spectacular Mississippi River views when morning fog lifts.

See all hotels in Hannibal

A river with a bridge, a town with buildings, and autumn-colored trees.

Top Hannibal Hotel Reviews

Find out more about Hannibal

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Hannibal are calling your name. Known for providing first-rate service in amazing locations, each of the Hannibal 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Hannibal. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Hannibal, Missouri, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Hannibal hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Hannibal?

With Expedia's handy filter tool, scoring an awesome deal on a 4-star hotel in Hannibal just got simpler. Start by entering your chosen arrival date and length of your break. Then list the results by price and choose the option that best fits your budget and style.

Search for the lowest price from CA $311

What's the difference between 5-star and 4-star hotels in Hannibal?

Give yourself the luxury treatment during your Hannibal vacation by staying at a 4-star hotel. As well as featuring upscale surroundings, these retreats are typically packed with amenities such as bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your trip an even more lavish and unforgettable one. 24-hour front desk, on-site spas and world-class dining are a few of the exclusive services and conveniences you'll likely have access to.

Does Hannibal have any 4-star all-inclusive resorts?

Enjoy a relaxing vacation experience where just about everything is included in the upfront price by using our "All inclusive" filter. Staying within budget is a cinch when your room, food, activities and entertainment are already taken care of. Eager for more ideas? Check out the amazing deals on our standard 4-star resorts in and around Hannibal.