Title: 4 Stars Hotels in Guadalupe District, Santa Fe - Find Cheap Guadalupe District Hotels With 4 Stars | Expedia.ca [Guadalupe District Travel Guide](https://expedia.ca/Santa-Fe-Guadalupe-District.dx553248635976481064)[Vacation Rentals in Santa Fe](https://expedia.ca/Santa-Fe-Vacation-Rentals.d180028.Travel-Guide-VacationRentals)[Flights to Santa Fe](https://expedia.ca/Cheap-Flights-To-Santa-Fe.d180028.Travel-Guide-Flights)[Things to do in Santa Fe](https://expedia.ca/Things-To-Do-In-Santa-Fe.d180028.Travel-Guide-Activities)[Guadalupe District Car Rentals](https://expedia.ca/Car-Rentals-In-Guadalupe-District.d553248635976481064.Car-Rental-Guide)[Guadalupe District Vacations](https://expedia.ca/Guadalupe-District.d553248635976481064.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/f43c118afa88b3b1014949c6b0ffe655.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Rick Tuers # 4 Stars Hotels in Guadalupe District, Santa Fe ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Guadalupe District 4 Star Hotels Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-12&endDate=2025-10-13&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-13&endDate=2025-10-14&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Guadalupe District 4 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Guadalupe-District-Santa-Fe-Hotels.s40-n553248635976481064-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Guadalupe-District-Santa-Fe-Hotels.s40-n553248635976481064-0.Travel-Guide-Filter-Hotels) ## Top Guadalupe District Hotel Reviews ![Hotel Santa Fe](//images.trvl-media.com/lodging/1000000/20000/19400/19360/1968861c_y.jpg) ### Hotel Santa Fe 10/10 Excellent "The room was well-appointed and the grounds were beautiful!" [](https://expedia.ca/Santa-Fe-Hotels-Hotel-Santa-Fe.h19360.Hotel-Information) ![Eldorado Hotel & Spa](//images.trvl-media.com/lodging/1000000/20000/13600/13524/d784e9ab_y.jpg) ### Eldorado Hotel & Spa 10/10 Excellent "Worth the coin." [](https://expedia.ca/Santa-Fe-Hotels-Eldorado-Hotel-Spa.h13524.Hotel-Information) ![Hilton Santa Fe Buffalo Thunder](//images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab_y.jpg) ### Hilton Santa Fe Buffalo Thunder 10/10 Excellent "Had a great stay. Room was great." [](https://expedia.ca/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) ![Inn and Spa at Loretto](//images.trvl-media.com/lodging/1000000/30000/26300/26264/b1f202d6_y.jpg) ### Inn and Spa at Loretto 10/10 Excellent "Beautiful place in a great location! People throughout were helpful nice and appreciative. Highly recommend. " [](https://expedia.ca/Santa-Fe-Hotels-Inn-And-Spa-At-Loretto.h26264.Hotel-Information) ![La Fonda on the Plaza](//images.trvl-media.com/lodging/1000000/10000/6700/6690/17bd5948_y.jpg) ### La Fonda on the Plaza 10/10 Excellent "Beautiful historic hotel. 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