Title: 3 Stars Hotels in Serenity Bay, Seneca from CA $112 - Find Cheap Serenity Bay Hotels With 3 Stars | Expedia.ca [Serenity Bay Travel Guide](https://expedia.ca/Seneca-Serenity-Bay.dx553248635976468572)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Serenity Bay Car Rentals](https://expedia.ca/Car-Rentals-In-Serenity-Bay.d553248635976468572.Car-Rental-Guide)[Serenity Bay Vacations](https://expedia.ca/Serenity-Bay.d553248635976468572.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 3 Stars Hotels in Serenity Bay, Seneca from CA $112 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Serenity Bay 3 Star Hotels Tonight [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-14&endDate=2025-10-15&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-15&endDate=2025-10-16&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Serenity Bay 3 Star Hotels ![View from property](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/05d8cd44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/e43af84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn Clemson 9.6/10 Exceptional (945) "Amazing place to stay. " CA $209 CA $232 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/a2328ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/64be157e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/11cd707b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/9f5c16fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Clemson Clemson 7.0/10 Good (192) "Rooms were clean. Check in was easy. TV and AC both worked great. Conveniently located to dining and shopping options. No issues or complaints. Would stay again. " CA $101 CA $112 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Clemson-Hotels-Days-Inn-By-Wyndham-Clemson.h15694.Hotel-Information) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/06863ceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/241a5cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square Clemson 9.8/10 Exceptional (765) "Beautiful hotel and close to restaurants and bars. " CA $209 CA $232 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/w3996h2667x0y0-e59088f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/0741038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/w4000h2664x0y0-3026bfef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/ef4e166d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Marriott Clemson Clemson 9.0/10 Wonderful (516) "Excellent!!! We loved everything about it!!! " CA $176 CA $195 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Courtyard-Marriott-Clemson.h2983181.Hotel-Information) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537364/091f0231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537364/54336ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537364/0f18b39a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537364/ead08738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Home With Balcony & Boat Dock! Seneca [](https://www.expedia.ca/Seneca-Hotels-Seneca-Home-W-Porch-Private-Dock-On-Lake-Keowee.h93537364.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537300/93537201/401c8d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537300/93537201/114dfb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537300/93537201/f936f99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537300/93537201/22f607eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Escape w/ Dock, Deck & Lake Access! Six Mile 10/10 Exceptional (1) "Awesome location as we visited our sons at Clemson Relaxing and beautiful location " [](https://www.expedia.ca/Six-Mile-Hotels-Lake-Keowee-Escape-W-Dock.h93537201.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94690000/94688900/94688898/w1024h495x0y264-b6ac5c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94690000/94688900/94688898/w1024h498x0y263-1a2add8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94690000/94688900/94688898/w1024h498x0y263-0481687e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94690000/94688900/94688898/w1024h496x0y264-cd095e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Point RV Townville 7.6/10 Good (10) "It was a pleasant cabin" [](https://www.expedia.ca/Townville-Hotels-The-Point-RV.h94688898.Hotel-Information) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/34f57420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/2e79c007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/a0c41c40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/90f42f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wooded Cottage - 3 Mi to Clemson University Clemson 10/10 Exceptional (1) [](https://www.expedia.ca/Clemson-Hotels-Pet-Friendly-Central-Cottage-2-Miles-To-Clemson.h93537325.Hotel-Information) ![Signature Cottage, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/7ab0b44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/2af03635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/2033b27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/e60c998d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson Memorabilia House Clemson 9.8/10 Exceptional (8) "Cute cottage and perfect location for visiting Clemson University. " CA $117 CA $324 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) ![Signature Cottage, 2 Bedrooms, Non Smoking, Patio | Private kitchen](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/a345cdb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms, Non Smoking, Patio | In-room dining](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/4b0f2aba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/777a66b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms, Non Smoking, Patio](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/abddcbb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Frank Howard 111 Farmhouse Clemson 9.8/10 Exceptional (10) "Great stay " CA $117 CA $324 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Clemson-Hotels-Frank-Howard-111-Farmhouse.h101436203.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/7fe924bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/1cb830f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/048e41bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/de0261d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Seneca Cabin ~ 4 Mi to Boat Launch! Seneca 10/10 Exceptional (1) "Beautiful and quaint cabin! Highly recommend, great view of the lake." [](https://www.expedia.ca/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537775/e4986f4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537775/89584578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537775/94084a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537775/1ed9de5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront Westminster Retreat w/ Boat Dock! Westminster [](https://www.expedia.ca/Westminster-Hotels-Lakefront-Westminster-Retreat-W-Boat-Dock.h93537775.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/55c118dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/6247e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/34ff4e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/ebe19f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deck, Grill & Dock Access: Lake Keowee Retreat! Seneca 10/10 Exceptional (1) "The best, perfect " [](https://www.expedia.ca/Seneca-Hotels-Deck.h113184450.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/e34f879b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/4964e86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/54580926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/9ca0994c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Screened Porch: Forested Tamassee Escape! Tamassee 10/10 Exceptional (1) "Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!" [](https://www.expedia.ca/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/98e162c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/2316b207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/ff30fd92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! Salem 10/10 Exceptional (1) "Property is in a great community, and it was very clean and beautifully decorated." [](https://www.expedia.ca/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106810000/106806300/106806289/8e64274d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106810000/106806300/106806289/96e49e92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106810000/106806300/106806289/9150593b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106810000/106806300/106806289/584317c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious Home w/ Porch, 4 Mi to Downtown Clemson! Central [](https://www.expedia.ca/Central-Hotels-Spacious-Home-W-Porch.h106806289.Hotel-Information) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94520000/94512800/94512724/48fde8cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94520000/94512800/94512724/f5964cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94520000/94512800/94512724/abf3f34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94520000/94512800/94512724/eca4a579.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Cottage: Yard + Deck, Walk to Downtown! Central 10/10 Exceptional (1) "Had a wonderful stay. Everything was great. We will be booking again." [](https://www.expedia.ca/Central-Hotels-Cozy-Cottage-Yard-Deck.h94512724.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537815/97409057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537815/c86bffd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537815/461951f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537815/20c76270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Home w/ Yard + Deck, 1 Mi to Clemson U! Clemson [](https://www.expedia.ca/Clemson-Hotels-Modern-Home-W-Yard-Deck.h93537815.Hotel-Information) ![Cottage (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537762/f7d01a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537762/b44587cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537762/aae3d1c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537762/ea98ed39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mountain Rest Cottage w/ Gas Fireplace! Mountain Rest 6.0/10 (1) "Unit is attached to the owners house. The drive way leading up to the apartment is loose gravel. Not safe for a heavy motorcycle. " [](https://www.expedia.ca/Mountain-Rest-Hotels-Lakefront-Mountain-Rest-Cottage-W-Gas-Fireplace.h93537762.Hotel-Information) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537428/e5e9f21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537428/74700e0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537428/61f1d632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537428/9c72f811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stunning Seneca Home w/ Lake Keowee Access! Seneca [](https://www.expedia.ca/Seneca-Hotels-Stunning-Seneca-Home-W-Lake-Keowee-Access.h93537428.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Serenity-Bay-Seneca-Hotels.s30-n553248635976468572-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Serenity-Bay-Seneca-Hotels.s30-n553248635976468572-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Serenity Bay. ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Shepherd Hotel Downtown Clemson 110 Sloan St, Clemson, SC CA $265 CA $294 total Oct 19 - Oct 20 includes taxes & fees 9.6/10 Exceptional! (701 reviews) [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![The Abernathy of Clemson](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Abernathy of Clemson 157 Old Greenville Hwy, Clemson, SC CA $201 CA $223 total Nov 3 - Nov 4 includes taxes & fees 9.6/10 Exceptional! (546 reviews) [](https://expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Liberty Hall Bed and Breakfast](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Liberty Hall Bed and Breakfast 621 S Mechanic St, Pendleton, SC CA $161 CA $249 total Oct 21 - Oct 22 includes taxes & fees 9.8/10 Exceptional! (74 reviews) [](https://expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Still don't see what you're looking for? [See all properties in Serenity Bay.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=15%2F10%2F2025&endDate=16%2F10%2F2025®ionId=553248635976468572&star=30) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=15%2F10%2F2025&endDate=16%2F10%2F2025®ionId=553248635976468572&star=30&star=30&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=15%2F10%2F2025&endDate=16%2F10%2F2025®ionId=553248635976468572&star=30&star=30&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=15%2F10%2F2025&endDate=16%2F10%2F2025®ionId=553248635976468572&star=30&star=30&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=15%2F10%2F2025&endDate=16%2F10%2F2025®ionId=553248635976468572&star=30&star=30&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=15%2F10%2F2025&endDate=16%2F10%2F2025®ionId=553248635976468572&star=30&star=30&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Serenity Bay Hotel Reviews ![Clemson University's James F. Martin Inn](//images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a_y.jpg) ### Clemson University's James F. Martin Inn 10/10 Excellent "This is a beautiful inn on the outskirts of Clemson's campus. The room is spacious, has good lighting and the beds are comfortable!! They seem a little short on outlets/charging stations, but we would definitely stay here again and recommend this location!!!!" [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Courtyard Marriott Clemson](//images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/w3996h2667x0y0-e59088f3_y.jpg) ### Courtyard Marriott Clemson 10/10 Excellent "Excellent!!! We loved everything about it!!! 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