Title: 3 Stars Hotels in Sanctuary, Sanibel from CA $105 - Find Cheap Sanctuary Hotels With 3 Stars | Expedia.ca [Sanctuary Travel Guide](https://expedia.ca/Sanibel-Sanctuary.dx553248635976469368)[Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Sanctuary.d553248635976469368.Car-Rental-Guide)[Sanctuary Vacations](https://expedia.ca/Sanctuary.d553248635976469368.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 3 Stars Hotels in Sanctuary, Sanibel from CA $105 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanctuary 3 Star Hotels Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-12&endDate=2025-10-13&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-13&endDate=2025-10-14&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sanctuary 3 Star Hotels ![Suite with King Bed, Beachfront, Balcony | Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/1808ce0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/767ba460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Beachfront, Balcony, Two Doubles](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/de245384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort Fort Myers Beach 8.8/10 Excellent (1038) "Very nice stay" CA $226 CA $284 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/030c0a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/044ddbbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/24e2211e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Ft Myers Villas 8.6/10 Excellent (1004) "Convenient location to shopping and dining very polite staff clean and luxurious room and delicious breakfast / Buffett will be returning " CA $165 CA $185 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/2ab8abc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/86e902b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort Mid Island 9.0/10 Wonderful (1330) "All around great place " CA $279 CA $346 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/b06bf9be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/w3000h1997x0y3-c76bf6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/4ec8c9b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/dd5699df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway Fort Myers 8.0/10 Very good (1016) "Great place to stay and breakfast was delicious " CA $117 CA $130 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Myers-Sanibel-Gateway.h11134.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/35893057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Offshore King, 1 Bedroom Studio (Family friendly, Not Pet Friendly)](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/348f4fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/2db9fe7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lighthouse Resort Inn & Suites Fort Myers Beach 8.6/10 Excellent (1498) "It was close to everything and I love their 2 bedroom suite options along with the Tiki Bar" [](https://www.expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/e5cac435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/2fcdc994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served, American cuisine, beach views ](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/50af8801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DiamondHead Beach Resort Fort Myers Beach 9.0/10 Wonderful (1014) "The staff was very profesional and friendly with us Nice place to stay " [](https://www.expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/63300/63247/6feb2ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/70000/63300/63247/1f24cb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/63300/63247/99df3a94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/70000/63300/63247/36b7aade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton - Fort Myers Villas 9.2/10 Wonderful (1004) "The rooms are spectacular, breakfast was amazing! " CA $167 CA $186 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Homewood-Suites-By-Hilton-Fort-Myers.h63247.Hotel-Information) ![Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, Multiple Beds, Beach View | Living room](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/1081c4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/b348cef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/96081da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edison Beach House Fort Myers Beach 9.4/10 Exceptional (1525) "very friendly staff" [](https://www.expedia.ca/Fort-Myers-Hotels-Edison-Beach-House.h11753200.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/8158a459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/e15af7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 Queen Beds Study with Patio](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/ea38270a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/16da23a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway Fort Myers Beach 8.4/10 Very good (1005) "Great stay - really friendly staff" CA $125 CA $140 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Hampton-Inn-Suites-Fort-Myers-BeachSanibel-Gateway.h551886.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/83cb6bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/e00a9bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/2c14a98f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/5f2e6784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Fort Myers Sanibel Fort Myers 8.6/10 Excellent (1005) "We loved the staff attitude and the excellent breakfast." CA $122 CA $136 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/faba246e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/1b9c29fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/23e15eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/cda8d432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dolphin Key Resort Caloosahatchee 8.8/10 Excellent (1181) "We have stayed here a few times and they never disappoint. " CA $140 CA $156 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a5c54d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a7398ba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/b4d8e8fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, kayaking, fishing](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/560da633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tween Waters Island Resort & Spa Captiva 8.6/10 Excellent (1003) "Stunning Beach View great Staff " CA $319 CA $404 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Tween-Waters-Island-Resort-Spa.h170769.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/476eda2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/54b01dcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/cfcc6858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral Villas 8.6/10 Excellent (757) "Staff was attentive and hotel was clean and quiet. " CA $99 CA $111 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/08b639cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/693ea816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites McGregor 7.6/10 Good (1007) "I like my stays here. Super quiet. Rooms are big. Nice pool & heated hot tub. " [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/6c1090cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/09cc3103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/0f55ab5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/925dd3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Inn East End 9.0/10 Wonderful (1002) "The reception was welcoming and the room we stayed in was excellent." CA $394 CA $521 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Inn.h40711.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/13e65390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/b3765e55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/407fdb8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/551a1a6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Fort Myers Sanibel Gateway by IHG South Fort Myers 7.4/10 Good (1004) "It was a great place to stay" CA $94 CA $105 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Candlewood-Suites-Fort-Myers-Sanibel-Gateway.h2292854.Hotel-Information) ![Outdoor pool, open 7:30 AM to 9:30 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/08406205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/0badd225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/05f74623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/91630e70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Resort & Marina Fort Myers Beach 8.6/10 Excellent (887) "Really enjoyed our stay! Made use of kayaks and felt comfortable and safe. Id def stay again! " CA $165 CA $185 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/40800/40732/aa4dca69_edited_4cce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/50000/40800/40732/a4b8b9b6_edited_be9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/40800/40732/12012e65_edited_c1ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Three Bedroom Bayside Villa Premier | Living area](https://images.trvl-media.com/lodging/1000000/50000/40800/40732/8decee9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### South Seas Resort Captiva 8.4/10 Very good (1007) "The property was very quiet, which it was great for me and my family, we needed it! We were able to celebrate my child's 14th birthday with what he likes the most, the beach and the pool and of course, food!" [](https://www.expedia.ca/Fort-Myers-Hotels-South-Seas-Island-Resort.h40732.Hotel-Information) ![Luxury Suite, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/57dffb5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/f9e5b71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Sea View | Private kitchen](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/e943aa9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Sea View | Balcony view](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/1fdb20ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Inn West End 9.4/10 Exceptional (1110) "A great place to enjoy the beach. Beautiful sunsets, We will definitely be back to Island Inn. Thanks for a great vacation!!!" CA $349 CA $389 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Hotels-Island-Inn.h1509747.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/fc463bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/a62366ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fishing](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/6e3a1f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/2a7931b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matanzas Inn Bayside Resort and Marina Fort Myers Beach 9.2/10 Wonderful (1005) "Clean, comfortable and great staff" CA $170 CA $225 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Fort-Myers-Hotels-Matanzas-Inn-Bayside-Resort-And-Marina.h2665085.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Sanctuary-Sanibel-Hotels.s30-n553248635976469368-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Sanctuary-Sanibel-Hotels.s30-n553248635976469368-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Sanctuary. ![Margaritaville Beach Resort Fort Myers ](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Beach Resort Fort Myers 251 Crescent Street, Fort Myers Beach, FL CA $221 CA $317 total Oct 13 - Oct 14 includes taxes & fees 8.8/10 Excellent! (1,529 reviews) [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 13051 Bell Tower Drive, Fort Myers, FL CA $175 CA $195 total Oct 19 - Oct 20 includes taxes & fees 8.8/10 Excellent! (1,007 reviews) [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Marriott Sanibel Harbour Resort & Spa 17260 Harbour Pointe Dr, Fort Myers, FL CA $225 CA $286 total Oct 26 - Oct 27 includes taxes & fees 8.2/10 Very Good! (1,006 reviews) [](https://expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) Still don't see what you're looking for? [See all properties in Sanctuary.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=30) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=30&star=30&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=30&star=30&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=30&star=30&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=30&star=30&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=553248635976469368&star=30&star=30&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Sanctuary Hotel Reviews ![The Lighthouse Resort Inn & Suites](//images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "our first time staying at the lighthouse . we really enjoyed our stay and actually extended one more nite , and have already booked another stay. sad to see all the extended damage from storm's But we found a new location to visit . We LOVE ft.Myers Beach " [](https://expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Homewood Suites by Hilton - Fort Myers](//images.trvl-media.com/lodging/1000000/70000/63300/63247/6feb2ef6_y.jpg) ### Homewood Suites by Hilton - Fort Myers 10/10 Excellent "Everything was excellent. Will definitely stay here again in the future." [](https://expedia.ca/Fort-Myers-Hotels-Homewood-Suites-By-Hilton-Fort-Myers.h63247.Hotel-Information) ![Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral](//images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a_y.jpg) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral 10/10 Excellent "None" [](https://expedia.ca/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ![Sanibel Island Beach Resort](//images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Fantastic experience. The place is beautifully restored. Lovely room, lovely ground, great beach access with hotel furnished lounge chairs. Perfect stay. " [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway](//images.trvl-media.com/lodging/1000000/20000/11200/11134/b06bf9be_y.jpg) ### La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway 10/10 Excellent "Friendly staff. Good location close to Sanibel Island." [](https://expedia.ca/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Myers-Sanibel-Gateway.h11134.Hotel-Information) ![Hilton Garden Inn Ft Myers](//images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a_y.jpg) ### Hilton Garden Inn Ft Myers 10/10 Excellent "The man that was working the night we checked in is very rude. We had two interactions with him and both were awful." [](https://expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![Residence Inn by Marriott Fort Myers Sanibel](//images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/83cb6bb9_y.jpg) ### Residence Inn by Marriott Fort Myers Sanibel 10/10 Excellent "." 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