Title: 3 Stars Hotels in Medical District, Greenville from CA $147 - Find Cheap Medical District Hotels With 3 Stars | Expedia.ca [Medical District Travel Guide](https://expedia.ca/Greenville-Medical-District.dx908649044914896896)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d2779.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Things to do in Greenville](https://expedia.ca/Things-To-Do-In-Greenville.d2779.Travel-Guide-Activities)[Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-District.d908649044914896896.Car-Rental-Guide)[Medical District Vacations](https://expedia.ca/Medical-District.d908649044914896896.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 3 Stars Hotels in Medical District, Greenville from CA $147 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Medical District 3 Star Hotels Tonight [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-12-19&endDate=2025-12-20&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 20 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-12-20&endDate=2025-12-21&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Medical District 3-star hotels ![Suite, 1 Bedroom, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/d55c4c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/82313f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/08b0695e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/10596374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Greenville, NC [](https://www.expedia.ca/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) Winterville 7.6/10 Good (820) "Staff was very friendly and property was in a convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele CA $129 CA $147 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/356f6fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/ce0cefde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/fdf12260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/2692ddf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Greenville Medical Center by IHG [](https://www.expedia.ca/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) Greenville 9.4/10 Exceptional (243) "I enjoyed my stay very clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LATONYA CA $138 CA $156 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/90561384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Bathtub](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/992488ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/36cd8e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/c64ceef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites By Hilton Greenville, NC [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) Greenville 9.4/10 Exceptional (308) "Room was perfect. We really appreciate our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol CA $159 CA $179 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/7d1b886f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/6d7fbebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/17061214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville by IHG [](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) Convention District 8.8/10 Excellent (1002) "Nice clean room. Very friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $134 CA $151 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3840h2556x0y4-0c33f88e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-c0bc68bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3836h2557x4y3-aaccaee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden INN Greenville University [](https://www.expedia.ca/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) Uptown Greenville 9.4/10 Exceptional (92) "Great location. Rooftop bar and restaurant was nice and convenient." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GEORGE CA $168 CA $190 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6060000/6057700/6057673/f8514e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/7000000/6060000/6057700/6057673/baaeb40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/7000000/6060000/6057700/6057673/849634ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6060000/6057700/6057673/ab4ea813.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Greenville [](https://www.expedia.ca/Greenville-Hotels-Residence-Inn-Greenville.h6057673.Hotel-Information) Greenville 8.8/10 Excellent (466) "Rooms are very nice, quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $153 CA $173 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Greenville-Hotels-Residence-Inn-Greenville.h6057673.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/e05fe4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/99c73073.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/d316ab0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/e37e6770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Marriott Greenville [](https://www.expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) Medical District 8.8/10 Excellent (881) "Clean rooms, friendly staff and great location. Enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frederick CA $163 CA $184 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119770000/119769300/119769289/fe516823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119770000/119769300/119769289/93dbdad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119770000/119769300/119769289/e2e41185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119770000/119769300/119769289/97c842d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 Mi to ECU Hospital: Greenville Home w/ Yard! [](https://www.expedia.ca/Greenville-Hotels-1-Mi-To-ECU-Campus-Greenville-Home-W-Yard.h119769289.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-1-Mi-To-ECU-Campus-Greenville-Home-W-Yard.h119769289.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111130000/111122200/111122159/d587fab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111130000/111122200/111122159/f8179877.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111130000/111122200/111122159/3d472341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111130000/111122200/111122159/46aad216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 Mi to Stadium: Home w/ Porch in Greenville! [](https://www.expedia.ca/Greenville-Hotels-1-Mi-To-Stadium-Home-W-Porch-In-Greenville.h111122159.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-1-Mi-To-Stadium-Home-W-Porch-In-Greenville.h111122159.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/103000000/102740000/102732000/102731912/a02b8fec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/103000000/102740000/102732000/102731912/64d574a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/103000000/102740000/102732000/102731912/87bd799f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/103000000/102740000/102732000/102731912/c0092c2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Home: 2 Mi to Downtown! [](https://www.expedia.ca/Greenville-Hotels-Greenville-Home-2-Mi-To-Downtown.h102731912.Hotel-Information) Greenville 10/10 Exceptional (1) "Very clean warm welcoming " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clarissa [](https://www.expedia.ca/Greenville-Hotels-Greenville-Home-2-Mi-To-Downtown.h102731912.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669829/f84e6a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669829/a4c4cd88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669829/77f25978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669829/c7cfe45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Game Day Ready: Greenville Stay w/ Patio Dining [](https://www.expedia.ca/Greenville-Hotels-Game-Day-Ready-Greenville-Stay-W-Patio-Dining.h119669829.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-Game-Day-Ready-Greenville-Stay-W-Patio-Dining.h119669829.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108060000/108060000/24025ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108060000/108060000/3188a2e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108060000/108060000/779a15b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108060000/108060000/02f68155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walkable Greenville Home Near Dtwn [](https://www.expedia.ca/Greenville-Hotels-Walkable-Greenville-Home-Near-Dtwn.h108060000.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-Walkable-Greenville-Home-Near-Dtwn.h108060000.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/107000000/106160000/106151400/106151347/fb1b28c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106160000/106151400/106151347/e68ec3ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106160000/106151400/106151347/bc550318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106160000/106151400/106151347/27ce0f60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Winterville Vacation Rental \~ 4 Mi to Ecu! [](https://www.expedia.ca/Winterville-Hotels-Winterville-Vacation-Rental-4-Mi-To-Ecu.h106151347.Hotel-Information) Winterville 9.0/10 Wonderful (2) "Stay was a success! Property was very clean and hosts communicated very well with instructions to everything on and in the property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa [](https://www.expedia.ca/Winterville-Hotels-Winterville-Vacation-Rental-4-Mi-To-Ecu.h106151347.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669835/d4ecd360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669835/bb9cdf0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669835/e4433a73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669835/a277590a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 6 Mi to Med District: Greenville Home w/ Yard [](https://www.expedia.ca/Winterville-Hotels-6-Mi-To-Med-District-Greenville-Home-W-Yard.h119669835.Hotel-Information) Winterville [](https://www.expedia.ca/Winterville-Hotels-6-Mi-To-Med-District-Greenville-Home-W-Yard.h119669835.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734110/82334071.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734110/025f5ac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734110/e1052532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734110/a21b046a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### < 2 Mi to ECU & Medical District: Retreat w/ Patio [](https://www.expedia.ca/Greenville-Hotels-2-Mi-To-ECU-Medical-District-Retreat-W-Patio.h119734110.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-2-Mi-To-ECU-Medical-District-Retreat-W-Patio.h119734110.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669837/da08a0a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669837/cb107db4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669837/0f7ca945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669837/75850297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Easy ECU Access: Modern Home w/ Patio! [](https://www.expedia.ca/Greenville-Hotels-Easy-ECU-Access-Modern-Home-W-Patio.h119669837.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-Easy-ECU-Access-Modern-Home-W-Patio.h119669837.Hotel-Information) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112110000/112106800/112106717/60600063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112110000/112106800/112106717/25a65944.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112110000/112106800/112106717/75c9aea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112110000/112106800/112106717/e0073dd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 9 Mi to Dtwn: Greenville Home w/ Screened Patio! [](https://www.expedia.ca/Greenville-Hotels-9-Mi-To-Dtwn-Greenville-Home-W-Screened-Patio.h112106717.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-9-Mi-To-Dtwn-Greenville-Home-W-Screened-Patio.h112106717.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669833/44a88297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669833/48ebaf80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669833/71228826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669833/ea96c393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pirate Game Day Base: Greenville Home Near Campus! [](https://www.expedia.ca/Greenville-Hotels-Pirate-Game-Day-Base-Greenville-Home-Near-Campus.h119669833.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-Pirate-Game-Day-Base-Greenville-Home-Near-Campus.h119669833.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112960000/112954100/112954038/44c4d317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112960000/112954100/112954038/7d074ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112960000/112954100/112954038/fb8aff57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112960000/112954100/112954038/d96a5c4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### < 2 Mi to Ecu: Cozy Greenville Getaway w/ Porch! [](https://www.expedia.ca/Greenville-Hotels-2-Mi-To-East-Carolina-University-Family-Home.h112954038.Hotel-Information) Greenville [](https://www.expedia.ca/Greenville-Hotels-2-Mi-To-East-Carolina-University-Family-Home.h112954038.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113300000/113290800/113290721/8e81a6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113300000/113290800/113290721/b88043db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113300000/113290800/113290721/0626d15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113300000/113290800/113290721/442eb997.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 8 Mi to Dtwn Greenville: Pet-friendly Family Home! [](https://www.expedia.ca/Bethel-Hotels-8-Mi-To-Dtwn-Greenville-Pet-Friendly-Family-Home.h113290721.Hotel-Information) Bethel [](https://www.expedia.ca/Bethel-Hotels-8-Mi-To-Dtwn-Greenville-Pet-Friendly-Family-Home.h113290721.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Medical-District-Greenville-Hotels.s30-n908649044914896896-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Medical-District-Greenville-Hotels.s30-n908649044914896896-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Medical District. ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/10000/1600/1575/39cdf1d9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Greenville 207 S.W. Greenville Blvd Greenville NC CA $191 CA $216 total Dec 28 - Dec 29 includes taxes & fees 8.6/10 Excellent! (532 reviews) [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h1575.Hotel-Information) Still don't see what you're looking for? [See all properties in Medical District.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F12%2F2025&endDate=22%2F12%2F2025®ionId=908649044914896896&star=30) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F12%2F2025&endDate=22%2F12%2F2025®ionId=908649044914896896&star=30&star=30&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F12%2F2025&endDate=22%2F12%2F2025®ionId=908649044914896896&star=30&star=30&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F12%2F2025&endDate=22%2F12%2F2025®ionId=908649044914896896&star=30&star=30&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F12%2F2025&endDate=22%2F12%2F2025®ionId=908649044914896896&star=30&star=30&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F12%2F2025&endDate=22%2F12%2F2025®ionId=908649044914896896&star=30&star=30&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Medical District Hotel Reviews ![Residence Inn by Marriott Greenville](https://images.trvl-media.com/lodging/7000000/6060000/6057700/6057673/f8514e6b_y.jpg) ### Residence Inn by Marriott Greenville 10/10 Excellent "Rooms are very nice, quiet " [](https://expedia.ca/Greenville-Hotels-Residence-Inn-Greenville.h6057673.Hotel-Information) ![Homewood Suites By Hilton Greenville, NC](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/36cd8e9e_y.jpg) ### Homewood Suites By Hilton Greenville, NC 10/10 Excellent "Room was great. Staff was indifferent." [](https://expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) ![Holiday Inn Greenville by IHG](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71_y.jpg) ### Holiday Inn Greenville by IHG 10/10 Excellent "Everything was good, except I just noticed some things that could use repair. Being in the maintenance industry, my eye is drawn to things that most may not see. Lights out in both elevators and in the elevator furthest from the office light is hanging in the elevator. Other than those things, I didn’t travel around the property very much but everything else I saw looked great. Customer service was fantastic. " [](https://expedia.ca/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) ![Staybridge Suites Greenville Medical Center by IHG](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/356f6fc4_y.jpg) ### Staybridge Suites Greenville Medical Center by IHG 10/10 Excellent "Spotless room and courteous staff!" [](https://expedia.ca/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) ![Courtyard Marriott Greenville](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/1f6092e1_y.jpg) ### Courtyard Marriott Greenville 10/10 Excellent "Clean rooms n friendly staff " [](https://expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) ![Country Inn & Suites by Radisson, Greenville, NC](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/d55c4c6b_y.jpg) ### Country Inn & Suites by Radisson, Greenville, NC 10/10 Excellent "Comfortable beds" [](https://expedia.ca/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) ![Hilton Garden INN Greenville University](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37_y.jpg) ### Hilton Garden INN Greenville University 10/10 Excellent "Great location. Rooftop bar and restaurant was nice and convenient." 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