Title: 2 Stars Hotels in Serra Mesa, San Diego from CA $87 - Find Cheap Serra Mesa Hotels With 2 Stars | Expedia.ca [Serra Mesa Travel Guide](https://expedia.ca/San-Diego-Serra-Mesa.dx553248635953501652)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Serra Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Serra-Mesa.d553248635953501652.Car-Rental-Guide)[Serra Mesa Vacations](https://expedia.ca/Serra-Mesa.d553248635953501652.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 2 Stars Hotels in Serra Mesa, San Diego from CA $87 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Serra Mesa 2 Star Hotels Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-05&endDate=2025-10-06&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-06&endDate=2025-10-07&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Serra Mesa 2 Star Hotels ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/50000/40800/40745/297b9804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40745/0303dbfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40745/e17b5b7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area Mission Valley 8.0/10 Very good (2139) "Nice place, great breakfast " CA $184 CA $212 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/24121852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/e0d53056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/760b1829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### California Suites Hotel Clairemont 7.6/10 Good (2085) "We enjoyed our stay." CA $112 CA $128 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/8104aff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/f52073d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kings Inn San Diego Mission Valley 8.8/10 Excellent (3434) "Great place to stay!" CA $113 CA $130 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/130000/126000/125995/990bbc2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/130000/126000/125995/c0685671.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/130000/126000/125995/1fc4ebbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126000/125995/e8daf68e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America San Diego - Sorrento Mesa Sorrento Valley 7.0/10 Good (1003) "Excellent place to stay in such an easy to get around area" CA $136 CA $156 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Diego-Hotels-Extended-Stay-America-Suites-San-Diego-Sorrento-Mesa.h125995.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/a98dc1ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/90271416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/4ea64dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/0566d122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn San Diego Point Loma 7.2/10 Good (1041) "Good place to stay" CA $92 CA $106 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/San-Diego-Hotels-Heritage-Inn-San-Diego-Near-SeaWorld.h2202716.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/b510fde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/97d07adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/cebdbfb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/1f0a5a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Palmeras Chula Vista Chula Vista 7.0/10 Good (1881) "Quiet area all around nice place to stay !!!" CA $101 CA $111 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Chula-Vista-Hotels-Hotel-Palmeras-Chula-Vista.h57248.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/a653b43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/4e3a5f44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/63e66623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/6af9aa5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 El Cajon, CA - San Diego El Cajon 7.2/10 Good (1392) "Great rooms for price " CA $86 CA $94 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/El-Cajon-Hotels-Motel-6-El-Cajon.h996144.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/4a0531e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/77e4221b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/76b95bec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego/Mission Valley Mission Valley 8.8/10 Excellent (1203) "Very clean hotel and feel very safe." CA $162 CA $187 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/ee1bc66b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/9325a8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/f928b115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/w5760h3822x0y0-bdfa11cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### GreenTree Inn San Diego Mission Bay Pacific Beach 8.0/10 Very good (1726) "Reasonable price with safety parking and excellent breakfast." CA $123 CA $142 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-Sea-World-Beach-Area.h428450.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/68b54340.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/c7295677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/e70fb26b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/2fd22763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Yacht Harbor Hotel Point Loma 8.6/10 Excellent (1535) "So close to so many dining options, clean and comfortable room and the pool was refreshing. Highly recommended. Thanks!!" CA $141 CA $161 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Yacht-Harbor-Hotel.h21527.Hotel-Information) ![Iron/ironing board, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49800/49799/14e421ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49800/49799/5d137296.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave](https://images.trvl-media.com/lodging/1000000/50000/49800/49799/074a2955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast buffet](https://images.trvl-media.com/lodging/1000000/50000/49800/49799/w2249h1500x275y0-eb26604d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Mission Valley/SDSU Del Cerro 5.8/10 (1007) "Great for an overnight stay" CA $101 CA $116 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-Mission-Valley-Qualcomm-Stadium-SDSU.h49799.Hotel-Information) ![Pillowtop beds, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/a459623d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/cea2c55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/039abc97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/59e49d5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express San Diego Downtown by IHG Downtown San Diego 8.4/10 Very good (1475) "It was a very clean and safe place to stay" CA $195 CA $226 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-Downtown.h40681.Hotel-Information) ![Hair dryer, towels](https://images.trvl-media.com/lodging/1000000/50000/40900/40892/56b97e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/40900/40892/413e298f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40892/bab90e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40892/8fcff8ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham National City/San Diego South National City 7.4/10 Good (1001) "Very good place to stay, close to the train and bus. " CA $82 CA $90 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/National-City-Hotels-Howard-Johnson-By-Wyndham-National-CitySan-Diego-South.h40892.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/fc9f5c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/14ea58da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/896515f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/d450dfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego-Downtown Downtown San Diego 8.2/10 Very good (2157) "Great place to stay" CA $217 CA $252 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Downtown.h551889.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/ed3f3759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/66a1c9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/31240634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/4093c285.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham San Diego Hotel Circle Mission Valley 7.2/10 Good (513) "Business friendly, great staff good location" CA $109 CA $125 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/bb0553a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/c58cd9b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/9a09438b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/4c055035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites San Diego Old Town Old Town San Diego 8.6/10 Excellent (1006) "The staff was so friendly and very helpful with everything! We had a great stay " CA $177 CA $204 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Fairfield-Inn-Suites-San-Diego-Old-Town.h11804.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/36500/36421/8aa155de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/40000/36500/36421/6aa0dfa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/36500/36421/2e7dcd2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/40000/36500/36421/591ab16b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites La Jolla – Windansea Beach by IHG Beach Barber Tract 8.8/10 Excellent (1002) "Great hotel " CA $248 CA $285 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/La-Jolla-Hotels-Holiday-Inn-Express-Suites-La-Jolla-Windansea-Beach.h36421.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/7e57ebb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/34519fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/w2155h1500x319y0-0ac4cd93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/28634394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### E-Z 8 Motel Old Town Old Town San Diego 6.4/10 (2119) "Friendly staff" CA $76 CA $87 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-E-Z-8-Motel-Old-Town.h15857616.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/e1f8ca63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/15f7656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/ec648405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/0cdeeab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Diego, CA - Hotel Circle - Mission Valley Mission Valley 6.8/10 (1457) "Close to places I want to visit. " CA $102 CA $117 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/36da2a73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/2e7509ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/434ca240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 7:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/6211d6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Chula Vista San Diego South Chula Vista 8.2/10 Very good (1129) "Good Hotel" CA $141 CA $156 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Chula-Vista-Hotels-Comfort-Inn-Chula-Vista-San-Diego-South.h18870.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Serra-Mesa-San-Diego-Hotels.s20-n553248635953501652-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Serra-Mesa-San-Diego-Hotels.s20-n553248635953501652-0.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Serra Mesa. ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Bay Club Hotel & Marina 2131 Shelter Island Dr, San Diego, CA CA $187 CA $215 total Oct 7 - Oct 8 includes taxes & fees 9/10 Wonderful! (2,972 reviews) [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The DEXTRO Little Italy, BW Premier Collection 1617 1st Avenue, San Diego, CA CA $166 CA $193 total Oct 13 - Oct 14 includes taxes & fees 8.6/10 Excellent! (494 reviews) [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Handlery Hotel 950 Hotel Cir N, San Diego, CA CA $142 CA $163 total Oct 8 - Oct 9 includes taxes & fees 8/10 Very Good! (2,133 reviews) [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) Still don't see what you're looking for? [See all properties in Serra Mesa.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=553248635953501652&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=553248635953501652&star=20&star=20&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=553248635953501652&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=553248635953501652&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=553248635953501652&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=553248635953501652&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Serra Mesa Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [1 Star Hotels in San Diego](https://www.expedia.ca/1Star-San-Diego-Hotels.s10-0-d3073.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Lincoln Park](https://www.expedia.ca/2Star-Lincoln-Park-San-Diego-Hotels.s20-n797413695373639680-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Pacific Beach](https://www.expedia.ca/2Star-Pacific-Beach-San-Diego-Hotels.s20-n6185751-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Downtown San Diego](https://www.expedia.ca/3Star-Downtown-San-Diego-San-Diego-Hotels.s30-n800123-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Gaslamp Quarter](https://www.expedia.ca/3Star-Gaslamp-Quarter-San-Diego-Hotels.s30-n6130021-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Mid-City](https://www.expedia.ca/3Star-Mid-City-San-Diego-Hotels.s30-n553248635976388682-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in San Diego](https://www.expedia.ca/3Star-San-Diego-Hotels.s30-0-d3073.Travel-Guide-Filter-Hotels) - 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(OAX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/oax/myf/oaxaca-intl-to-san-diego) - [Flights from Oceanside (OCN) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ocn/myf/oceanside-to-san-diego) - [Flights from Nogales (OLS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ols/myf/nogales-to-san-diego) - [Flights from Omaha (OMA) to San Diego (MYF)](https://www.expedia.ca/lp/flights/oma/myf/omaha-to-san-diego) - [Flights from Phoenix (PHX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/phx/myf/phoenix-to-san-diego) - [Flights from Pompano Beach (PPM) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ppm/myf/pompano-beach-to-san-diego) - [Flights from Murrieta (RBK) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rbk/myf/murrieta-to-san-diego) - [Flights from Redding (RDD) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rdd/myf/redding-to-san-diego) - [Flights from Rifle (RIL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ril/myf/rifle-to-san-diego) - [Flights from Mariposa (RMY) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rmy/myf/mariposa-to-san-diego) - [Flights from Reno (RNO) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rno/myf/reno-to-san-diego) - [Flights from Seattle (SEA) to San Diego (MYF)](https://www.expedia.ca/lp/flights/sea/myf/seattle-to-san-diego) - [Flights from San Francisco (SFO) to San Diego (MYF)](https://www.expedia.ca/lp/flights/sfo/myf/san-francisco-to-san-diego) - [Flights from Spearfish (SPF) to San Diego (MYF)](https://www.expedia.ca/lp/flights/spf/myf/spearfish-to-san-diego) - [Flights from San Carlos (SQL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/sql/myf/san-carlos-to-san-diego) - [Flights from Santa Paula (SZP) to San Diego (MYF)](https://www.expedia.ca/lp/flights/szp/myf/santa-paula-to-san-diego) - [Flights from Tacoma (TIW) to San Diego (MYF)](https://www.expedia.ca/lp/flights/tiw/myf/tacoma-to-san-diego) - [Flights from Temple (TPL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/tpl/myf/temple-to-san-diego) - [Flights from Watsonville (WVI) to San Diego (MYF)](https://www.expedia.ca/lp/flights/wvi/myf/watsonville-to-san-diego) - [Flights from Ottawa (YOW) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yow/myf/ottawa-to-san-diego) - [Flights from Montreal (YUL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yul/myf/montreal-to-san-diego) - [Flights from Yuma (YUM) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yum/myf/yuma-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yvr/myf/vancouver-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yvr/san/vancouver-to-san-diego) - [Flights from Winnipeg (YWG) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ywg/myf/winnipeg-to-san-diego) - [Flights from Calgary (YYC) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yyc/myf/calgary-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yyz/myf/toronto-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yyz/san/toronto-to-san-diego) - [Visit Birdland](https://www.expedia.ca/San-Diego-Birdland.dx553248635976479135) - [Book Hotels in Serra Mesa on Expedia.com](https://www.expedia.com/2Star-Serra-Mesa-San-Diego-Hotels.s20-n553248635953501652-0.Travel-Guide-Filter-Hotels)