Title: 2 Stars Hotels in Medical Center District, San Antonio from CA $67 - Find Cheap Medical Center District Hotels With 2 Stars | Expedia.ca [Medical Center District Travel Guide](https://expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844)[Vacation Rentals in San Antonio](https://expedia.ca/San-Antonio-Vacation-Rentals.d178303.Travel-Guide-VacationRentals)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.ca/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Medical Center District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-Center-District.d553248635978913844.Car-Rental-Guide)[Medical Center District Vacations](https://expedia.ca/Medical-Center-District.d553248635978913844.Destination-Travel-Guides) ![SanAntonio_SouthTexasMedicalCenter_6193120_01](https://images.trvl-media.com/place/6193120/6208bc73-d0ab-4fda-b1af-d2c1bae086ed.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 2 Stars Hotels in Medical Center District, San Antonio from CA $67 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Medical Center District 2 Star Hotels Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-18&endDate=2025-12-19&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-19&endDate=2025-12-20&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Medical Center District 2-star hotels ![Premium bedding, desk, laptop workspace, free cribs/infant beds](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/0716970b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/e7d952d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, free cribs/infant beds](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/92301729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/3a049706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott San Antonio Medical Center [](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information) Medical Center District 9.0/10 Wonderful (1004) "Everything was great, staff really kind ..." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) traci CA $114 CA $134 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/82b9f830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/c7209e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/863e2a8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/daa37cb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 San Antonio, TX - Medical Center [](https://www.expedia.ca/San-Antonio-Hotels-Studio-6-San-Antonio.h50914.Hotel-Information) Medical Center District 6.6/10 (787) "Staff and amenities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keyshia CA $67 CA $82 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Antonio-Hotels-Studio-6-San-Antonio.h50914.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/9628dbca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/f2ac3195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/ea511f30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/fea7afce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson [](https://www.expedia.ca/San-Antonio-Hotels-Welcome-Inn-San-Antonio-Medical-Center.h28102.Hotel-Information) Medical Center District 7.2/10 Good (1000) "Staff were amazing, and everything else was great too. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maximilian CA $87 CA $101 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Welcome-Inn-San-Antonio-Medical-Center.h28102.Hotel-Information) ![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/1e45b6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/9cc70423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/b35dac08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/9eaddd06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 San Antonio, Tx - Northwest Medical Center [](https://www.expedia.ca/San-Antonio-Hotels-Studio-6-San-Antonio.h83405963.Hotel-Information) Medical Center District 7.2/10 Good (217) "Clean, and accommodating room was very a very good Choice!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $73 CA $85 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Studio-6-San-Antonio.h83405963.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/5f526f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/8b9aed83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/ef1bc714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/33c180e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Antonio, TX - Northwest Medical Center [](https://www.expedia.ca/San-Antonio-Hotels-Motel-6-San-Antonio.h50555.Hotel-Information) Medical Center District 6.0/10 (1002) "Staff courteous." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleeen CA $59 CA $70 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Motel-6-San-Antonio.h50555.Hotel-Information) ![Basic Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/53fea236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/00bf65b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/52d716c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/42431698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Flex Studios [](https://www.expedia.ca/San-Antonio-Hotels-Flex-Studios.h75211602.Hotel-Information) Medical Center District 6.0/10 (497) "heb is nearby. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sayeed CA $57 CA $67 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/San-Antonio-Hotels-Flex-Studios.h75211602.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/1b117ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 Queen Deluxe Suites | Bathroom](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/d7b70ede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Deluxe Suite](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/76d52754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Deluxe Suite](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/3d551d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Atria Inn & Suites [](https://www.expedia.ca/San-Antonio-Hotels-9727-Fredericksburg-Rd.h96182039.Hotel-Information) Medical Center District 7.6/10 Good (276) "Nice, comfortable space for a reasonable price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia [](https://www.expedia.ca/San-Antonio-Hotels-9727-Fredericksburg-Rd.h96182039.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/41551429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/e974d0cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/6d7e3cbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/a061f3de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Inn & Suites Medical Center San Antonio [](https://www.expedia.ca/San-Antonio-Hotels-OYO-Inn-Suites-Medical-Center-San-Antonio.h692534.Hotel-Information) Medical Center District 7.2/10 Good (225) "Always great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan [](https://www.expedia.ca/San-Antonio-Hotels-OYO-Inn-Suites-Medical-Center-San-Antonio.h692534.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25800/25742/dabe524d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/25800/25742/13c6ef89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/25800/25742/bb31e3f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/25800/25742/d397b450.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Pointe near Medical Center [](https://www.expedia.ca/San-Antonio-Hotels-Clarion-Pointe.h25742.Hotel-Information) Medical Center District 6.8/10 (1237) "Great stay thank you" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana [](https://www.expedia.ca/San-Antonio-Hotels-Clarion-Pointe.h25742.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/107000000/106530000/106526900/106526806/5189e989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/107000000/106530000/106526900/106526806/d02a0ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/107000000/106530000/106526900/106526806/127ae368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/107000000/106530000/106526900/106526806/a4a41c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3 bedroom Home with Backyard [](https://www.expedia.ca/San-Antonio-Hotels-Spacious-3-Bedroom-Home-With-Backyard.h106526806.Hotel-Information) Medical Center District 9.4/10 Exceptional (3) "The house was perfect for our stay. Clean and lots of space, we had zero problems. The location was close to everything, and I would recommend this place to others. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LAURA S. CA $147 CA $400 total includes taxes & fees Jan 19 - Jan 20, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Spacious-3-Bedroom-Home-With-Backyard.h106526806.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/107000000/106090000/106080300/106080271/66b7935e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106090000/106080300/106080271/7c9a55a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/107000000/106090000/106080300/106080271/83e9e5b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/107000000/106090000/106080300/106080271/736307d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Comfort: 1 BR/ Medical Center/Resort Style [](https://www.expedia.ca/San-Antonio-Hotels-Cozy-Blue-Haven-1-Bedroom-Near-Medical-Center14-Mins-From-Airport.h106080271.Hotel-Information) Medical Center District 3.4/10 (3) "Overall the room was okay. It was easy to find. The bed was comfortable and the towels and sheets were clean. On the other hand, we received a message that our room would not be ready until 3 hours after our check in time. After flying all day it was not something we wanted to hear. The floor was completely filthy. I had to go buy socks and wear them around the place. (Which the bottoms were nearly black) there was hair in the bathroom which always grosses me out. The couch was comfortable but... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim D. [](https://www.expedia.ca/San-Antonio-Hotels-Cozy-Blue-Haven-1-Bedroom-Near-Medical-Center14-Mins-From-Airport.h106080271.Hotel-Information) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94320000/94316200/94316197/26d6afb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94320000/94316200/94316197/2c4631c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/95000000/94320000/94316200/94316197/ab2ce43b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94320000/94316200/94316197/69d1a290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming San Antonio Abode \~ 10 Mi to River Walk! [](https://www.expedia.ca/San-Antonio-Hotels-Charming-San-Antonio-Abode-10-Mi-To-River-Walk.h94316197.Hotel-Information) Medical Center District [](https://www.expedia.ca/San-Antonio-Hotels-Charming-San-Antonio-Abode-10-Mi-To-River-Walk.h94316197.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107900000/107895100/107895045/b13157ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107900000/107895100/107895045/ec7094c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107900000/107895100/107895045/49294fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/108000000/107900000/107895100/107895045/7ef5b5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Paloma - Stunning Luxurious Villa w/ Pool [](https://www.expedia.ca/San-Antonio-Hotels-Stunning-Luxurious-Villa-W-Pool.h107895045.Hotel-Information) Medical Center District 10/10 Exceptional (1) [](https://www.expedia.ca/San-Antonio-Hotels-Stunning-Luxurious-Villa-W-Pool.h107895045.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/107000000/106050000/106044400/106044377/daf9be2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106050000/106044400/106044377/775d3b23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/107000000/106050000/106044400/106044377/ac865684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106050000/106044400/106044377/83094405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blue Oasis: 1-BR Apartment with Premium Amenities [](https://www.expedia.ca/San-Antonio-Hotels-Cozy-Blue-Haven-One-Bedroom-Retreat-Near-Medical-Center.h106044377.Hotel-Information) Medical Center District 5.6/10 (5) "Check in was easy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MaryAnne K. [](https://www.expedia.ca/San-Antonio-Hotels-Cozy-Blue-Haven-One-Bedroom-Retreat-Near-Medical-Center.h106044377.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/1000000/30000/24100/24028/727414f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/24100/24028/1f791981.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24100/24028/615acacf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/24100/24028/9746bc2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham San Antonio Near South Texas Medical Ctr [](https://www.expedia.ca/San-Antonio-Hotels-Baymont-By-Wyndham-San-Antonio-Near-South-Texas-Medical-Ctr.h24028.Hotel-Information) Medical Center District 5.6/10 (1001) "It was so good, guys were pretty nice and friendly. It was so easy, the only think maybe the smell of cigarette was intense...but It was the only thing" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Laura Leticia [](https://www.expedia.ca/San-Antonio-Hotels-Baymont-By-Wyndham-San-Antonio-Near-South-Texas-Medical-Ctr.h24028.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109400000/109391900/109391868/8f04e90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/110000000/109400000/109391900/109391868/aded48df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109400000/109391900/109391868/6126641c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, stereo, offices](https://images.trvl-media.com/lodging/110000000/109400000/109391900/109391868/0c8d8072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Upscale Furnished Apartment near La Cantera & San Antonio Medical Center [](https://www.expedia.ca/San-Antonio-Hotels-Discover-Your-Upscale-Retreat-In-Historic-San-Antonio-This-Modern-Apartment-Offers-A-Seamless-Blend-Of-Comfort-And-Convenience.h109391868.Hotel-Information) Medical Center District CA $104 CA $474 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Discover-Your-Upscale-Retreat-In-Historic-San-Antonio-This-Modern-Apartment-Offers-A-Seamless-Blend-Of-Comfort-And-Convenience.h109391868.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/290000/282700/282656/896e8820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/290000/282700/282656/01ad555b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/290000/282700/282656/c1f0d539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/290000/282700/282656/895349d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Siegel Select San Antonio [](https://www.expedia.ca/San-Antonio-Hotels-Siegel-Select-San-Antonio.h282656.Hotel-Information) Medical Center District 7.0/10 Good (373) "Sucio, mal cuidado y el servicio o es malo ya que no hacen linpieza de los cuartos y de los baños diario.NUNCA REGRESARÉ " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Edgardo [](https://www.expedia.ca/San-Antonio-Hotels-Siegel-Select-San-Antonio.h282656.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/121000000/120830000/120821400/120821399/76fdab38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/121000000/120830000/120821400/120821399/0dc74e3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/121000000/120830000/120821400/120821399/dedb0914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/121000000/120830000/120821400/120821399/6f625044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Freshly Remodeled Long Term 2BR Condo with Pool Access in Gated Community [](https://www.expedia.ca/San-Antonio-Hotels-Freshly-Remodeled-Long-Term-2BR-Condo-With-Pool-Access-In-Gated-Community.h120821399.Hotel-Information) Medical Center District [](https://www.expedia.ca/San-Antonio-Hotels-Freshly-Remodeled-Long-Term-2BR-Condo-With-Pool-Access-In-Gated-Community.h120821399.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Medical-Center-District-San-Antonio-Hotels.s20-n553248635978913844-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Medical-Center-District-San-Antonio-Hotels.s20-n553248635978913844-0.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Medical Center District. ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW 4431 Horizon Hill Blvd San Antonio TX CA $122 CA $145 total Dec 20 - Dec 21 includes taxes & fees 8.4/10 Very Good! (3,119 reviews) [](https://expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![San Antonio Marriott Northwest Medical Center](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/aa83e7de_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### San Antonio Marriott Northwest Medical Center 3233 NW Loop 410 San Antonio TX CA $109 CA $130 total Jan 4 - Jan 5, 2026 includes taxes & fees 8.4/10 Very Good! (1,006 reviews) [](https://expedia.ca/San-Antonio-Hotels-San-Antonio-Marriott-Northwest.h4192.Hotel-Information) ![SpringHill Suites by Marriott San Antonio Medical Center/NW](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/32f5e634_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### SpringHill Suites by Marriott San Antonio Medical Center/NW 3636 NW Loop 410 San Antonio TX CA $139 CA $164 total Dec 20 - Dec 21 includes taxes & fees 8.6/10 Excellent! (1,001 reviews) [](https://expedia.ca/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information) Still don't see what you're looking for? [See all properties in Medical Center District.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635978913844&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635978913844&star=20&star=20&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635978913844&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635978913844&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635978913844&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635978913844&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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