Title: 10 Best Hotels in Mayo Clinic, Phoenix for 2025 | Expedia.ca

 

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# Hotels in Mayo Clinic, Phoenix

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## Go beyond your typical stay in Mayo Clinic

Resort

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=HOTEL_RESORT)

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=SPA_ON_SITE)

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=APART_HOTEL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&travelerType=family_friendly)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=APARTMENT)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=POOL)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=HOT_TUB)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=COTTAGE)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=VILLA)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=CONDO)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=WATER_PARK)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Mayo+Clinic%2C+Scottsdale%2C+Arizona%2C+United+States+of+America&regionId=553248635976008216&latLong=33.585751%2C-111.792158&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=PETS)

## Check prices for these dates

Tonight

[Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Mayo Clinic hotels and places to stay

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/3d96914a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite, 1 King Bed with Sofa bed (One Bedroom) | Living area](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/f2d46939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/a321f9f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/cf4c5bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sonesta Select Scottsdale at Mayo Clinic Campus

Mayo Clinic

8.2/10

Very good

(1039)

"Everyone was extremely pleasant and the location was close to many amenities. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

CA $139

CA $158 total

includes taxes & fees

Nov 25 - Nov 26

[](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information)

![Outdoor pool, open 7 AM to 10 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/30000000/29860000/29856300/29856292/5c829baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/30000000/29860000/29856300/29856292/73259d81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/30000000/29860000/29856300/29856292/b48d9664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/30000000/29860000/29856300/29856292/4a79b95d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Phoenix East - Gilbert by IHG

24 km from Mayo Clinic

9.4/10

Exceptional

(982)

"The room was clean and neat. Excellent breakfast and facilities. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maried

CA $171

CA $196 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Phoenix-Hotels-Holiday-Inn-Express-Suites-Phoenix-East-Gilbert.h29856292.Hotel-Information)

![Gazebo](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/d40464a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Non Smoking, Pool View (1King Bed)](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/f747ca46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/ec842895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/a1dc1969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

24.1 km from Mayo Clinic

8.2/10

Very good

(1779)

"Good place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $115

CA $132 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Phoenix-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Mesa-Superstition-Springs.h84750.Hotel-Information)

![Room, 2 Queen Beds, Accessible](https://images.trvl-media.com/lodging/1000000/10000/3800/3749/7b43a1e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3800/3749/d9113760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3800/3749/94d89bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/3800/3749/57f19f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn & Suites by Wyndham Mesa Near Phoenix

23 km from Mayo Clinic

9.0/10

Wonderful

(1970)

"The rooms are nice and beds are comfy! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joseph

CA $100

CA $114 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Phoenix-Hotels-Days-Hotel-By-Wyndham-Mesa-Near-Phoenix.h3749.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64200/64122/68d3cac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 7 AM to 10 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/64200/64122/cf3e64a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64122/d9c9038c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, blackout drapes, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/1000000/70000/64200/64122/793aba7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western North Phoenix Hotel

29.9 km from Mayo Clinic

8.8/10

Excellent

(1037)

"Room clean and comfortable. Staff friendly and accommodating. AC a little noisy but other than a nice stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patricia

CA $136

CA $154 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Phoenix-Hotels-Best-Western-North-Phoenix-Hotel.h64122.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40300/40296/f7bc38d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40300/40296/377b32ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40300/40296/5c972f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/40300/40296/4e192751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SureStay Plus by Best Western Mesa Superstition Springs

23.4 km from Mayo Clinic

8.4/10

Very good

(1615)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Niel

CA $111

CA $127 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Phoenix-Hotels-Sleep-Inn-Mesa-Superstition-Springs-Center.h40296.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116800/116799/1e60ba0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/120000/116800/116799/7b602c24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/116800/116799/40ecb898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/116800/116799/1cb44a23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, Mesa, AZ

24.3 km from Mayo Clinic

7.8/10

Good

(1001)

"Refurbished hotel but great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Conie

CA $130

CA $148 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Phoenix-Hotels-Country-Inn-Suites-By-Radisson.h116799.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1250000/1246400/1246316/fda935d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1250000/1246400/1246316/19811735.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1250000/1246400/1246316/0bf39069.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/2000000/1250000/1246400/1246316/7c6e8273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wekopa Casino Resort

10.1 km from Mayo Clinic

9.2/10

Wonderful

(1000)

"Very clean and quiet, staff is nice, free breakfast is amazing and pool area is wonderful and clean and quiet"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bonnie

CA $193

CA $260 total

includes taxes & fees

Nov 18 - Nov 19

[](https://www.expedia.ca/Phoenix-Hotels-Wekopa-Casino-Resort.h1246316.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/2000000/1840000/1838000/1837951/c19673d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 9:00 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1840000/1838000/1837951/c47b70ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1840000/1838000/1837951/eb955d4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/2000000/1840000/1838000/1837951/1a2348ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Azure Hotel

19.1 km from Mayo Clinic

8.8/10

Excellent

(1576)

"Hotel was ok and clean. The breakfast is more of a coffee and pastry stop. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $127

CA $152 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Phoenix-Hotels-The-Azure-Hotel.h1837951.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/bd5c95c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/a6edea6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/86658d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Phoenix Tapatio Cliffs Resort

25.4 km from Mayo Clinic

8.6/10

Excellent

(2168)

"Very pleasant place, it was beautiful! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Miryam

CA $148

CA $229 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information)

![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/4fb94d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/c8f78ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/0f659cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6802/4ca4b17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Phoenix

30 km from Mayo Clinic

9.2/10

Wonderful

(1867)

"Nice place good staff and enjoyable stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shane

CA $237

CA $307 total

includes taxes & fees

Nov 22 - Nov 23

[](https://www.expedia.ca/Phoenix-Hotels-Hyatt-Regency-Phoenix.h6802.Hotel-Information)

![Balcony](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/9cb71336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, rainfall showerhead, designer toiletries, hair dryer](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/e9fa5518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/a0a768b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### FOUNDRE Phoenix

29.6 km from Mayo Clinic

9.2/10

Wonderful

(2157)

"Staff was great. Beds were comfy and water was hot! Loved the art and desgn. Very cool hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $170

CA $230 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474826/4406d52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474826/c9b1b524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, blackout drapes, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474826/568d4fb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474826/3be771f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites by Hilton Mesa Longbow, AZ

14.7 km from Mayo Clinic

9.6/10

Exceptional

(628)

"Excellent stay the breakfast was a major plus friendly staff overall a great experience"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JOSE

CA $178

CA $204 total

includes taxes & fees

Nov 25 - Nov 26

[](https://www.expedia.ca/Phoenix-Hotels-Home2-Suites-By-Hilton-Mesa-Longbow.h64474826.Hotel-Information)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/80000/79400/79362/38841bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79400/79362/36dd7896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/80000/79400/79362/d5dea7e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/80000/79400/79362/af36a111.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sonesta Simply Suites Phoenix Glendale

30 km from Mayo Clinic

8.0/10

Very good

(1048)

"Good location for our short term needs"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Paul

CA $133

CA $150 total

includes taxes & fees

Nov 25 - Nov 26

[](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Simply-Suites-Phoenix.h79362.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84600/84520/0b69a7e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84600/84520/b59eb39b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84600/84520/f5138f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/90000/84600/84520/ee97462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Phoenix Mesa West

22.4 km from Mayo Clinic

7.6/10

Good

(1447)

"Hotel in a nice area. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James

CA $114

CA $130 total

includes taxes & fees

Nov 18 - Nov 19

[](https://www.expedia.ca/Phoenix-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Phoenix-Mesa-West.h84520.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/72000000/71550000/71546200/71546102/4fdf5859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/72000000/71550000/71546200/71546102/05b4d49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/72000000/71550000/71546200/71546102/bf237a23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/72000000/71550000/71546200/71546102/53e585e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Scottsdale Talking Stick Entertainment District

9.7 km from Mayo Clinic

9.2/10

Wonderful

(1750)

"staff was great perfect location for shopping and dining out"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Javier

CA $135

CA $153 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Phoenix-Hotels-Comfort-Suites-Scottsdale-Talking-Stick-Entertainment-District.h71546102.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/16000000/15120000/15118200/15118122/37cda094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/16000000/15120000/15118200/15118122/6b3693c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/16000000/15120000/15118200/15118122/be0fdf0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15120000/15118200/15118122/ececb6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Phoenix East Mesa

23.5 km from Mayo Clinic

9.2/10

Wonderful

(1001)

"The staff was awesome! Everything was clean!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tami

CA $192

CA $219 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Phoenix-Hotels-Hampton-Inn-Suites-Phoenix-East-Mesa.h15118122.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/30000000/29390000/29381000/29380970/24058b43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/30000000/29390000/29381000/29380970/6a7b8e9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/30000000/29390000/29381000/29380970/632fdba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/30000000/29390000/29381000/29380970/1eaf7655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Phoenix East - Gilbert by IHG

24 km from Mayo Clinic

9.6/10

Exceptional

(842)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $226

CA $259 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Phoenix-Hotels-Staybridge-Suites-Phoenix-East-Gilbert.h29380970.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/23000000/22280000/22270800/22270752/755830f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/23000000/22280000/22270800/22270752/3538d95e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dinner served](https://images.trvl-media.com/lodging/23000000/22280000/22270800/22270752/acd8b54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/23000000/22280000/22270800/22270752/c833518b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Phoenix Downtown

30 km from Mayo Clinic

9.2/10

Wonderful

(1643)

"Great place to stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Crayton

CA $171

CA $194 total

includes taxes & fees

Nov 22 - Nov 23

[](https://www.expedia.ca/Phoenix-Hotels-Hampton-Inn-Suites-Phoenix-Downtown.h22270752.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/90000000/89790000/89782500/89782425/85548a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/90000000/89790000/89782500/89782425/dac8b9cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/90000000/89790000/89782500/89782425/4c233acf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/90000000/89790000/89782500/89782425/a9a807e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Papago Scottsdale by Reside, Trademark Collection by Wyndham

18.5 km from Mayo Clinic

8.6/10

Excellent

(203)

"Well done rehab of an older property. Good value"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Scott

CA $136

CA $155 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Phoenix-Hotels-Papago-Motor-Hotel.h89782425.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&regionId=553248635976008216&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.

-   Downtown Phoenix
-   Old Town
-   Camelback East
-   Central Scottsdale
-   Paradise Valley Village

![Downtown Phoenix showing signage and night scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/190000/190372-Downtown-Phoenix.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/543000/543565-downtown-phoenix.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/543000/543566-downtown-phoenix.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478460-Phoenix.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/541000/541466-downtown-phoenix.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6253445)

![Downtown Phoenix map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:khgkEjmgkTZuqDKauK%7EdBqrCxf%40ckAfp%40kK%60G%60%40x%5E%60nB%60GtWzCtWpKl%5Bvg%40diB%7EBdf%40sA%60Ov%40xh%40gR%7C_AcFtf%40gAbWv%40%7CS_CvXsJfIaCtPrFpGLjKzLhRqB%5Ek%40hJbKfClLb%5E%7CKvIdWre%40%60C%60VuhBp%40uAp%5CsNbPuJhC%7BaD%60%40mf%40fI&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=mptJ6ZuNOT10GZv9smlYjlE9SLc=)

### Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6253445)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479003-Old-Town-Scottsdale.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479015-Old-Town-Scottsdale.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479013-Old-Town-Scottsdale.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479014-Old-Town-Scottsdale.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479012-Old-Town-Scottsdale.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6160565)

![Old Town map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:alnkEjgejToUIFut%40zUHSmu%40nV%3FKtG_AlDDv%5BhEmKbD%7DBxKC%3FqKvW%3FbF_%40%40wDjLH%3FhR%7DHPK%60SsAjBGbB%7EKGaHvBuAlEMdHiCjDgP%7EAJnO%7EA%7EHqPQyOwZiM%3FsDtA_EI%3FfY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=JauPTSjqoxVIRgZfWZA1a6pi91E=)

### Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Scottsdale Waterfront and Western Spirit: Scottsdale's Museum of the West.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6160565)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478428-Phoenix.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/543000/543141-arizona.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/543000/543143-arizona.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/543000/543274-camelback-east.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/543000/543275-camelback-east.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6253428)

![Camelback East map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_gxkEjv%7EjT%7DBa%7CAaJsNEiVoVic%40iOgCwFoCoDgGwTug%40xvAmsEv_%40SpS%7E%40hKa%40%7EONAg%40rp%40j%40C%60nBtt%40b%40j%5Eo%40hOke%40%7CAqGxDaWxDuHUk%5CiaA%5BoDuMYsDZuUl%40%7DBvBgCl%40mCFo%7D%40%5B_CZqB%40sHrI%40Nw%5B%60d%40%7EAr%40_%7E%40vq%40cw%40tEzF%7E%40%5BrAcCfDSzGt%40vBbD%60Br%40j%7DAL%40qL%60Nu%40z%40eABuAbIBB%60BfA%3Fj%40%7EHrCvGgAvCfJ%7CWn%40LFhVll%40Da%40%7DkBnb%40SnGd%40%7C%40mYzHSfDnDdIdEpB%5EbJ%60AvOC%7CCxD%7ECr%40hNmFvCkE%60IiEhRvIjC%7Eu%40jFgCkFvWjJtCEz%40Gx%40%7BSUkAz%40OvCiArANrGq%40NClTfv%40p%40%7EAe%40H%7DA%3F%7CAdAk%40bFd%40dFGg%40dsAf%40xKEf%40%5DW%7C%40%7EM_f%40xHyAlCsB%7C%40oCxM%7BPjb%40ui%40%7EbAyWr%60%40h%40hMsKjAoZ%7Ee%40%7D%7D%40fnAub%40xf%40iTvY%7DI%7CSgC%7CBw%5CdOcb%40xf%40m%5Bzm%40kDtO_AzViyHX&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=66acE8aS4T4NvEIZa_3BTLAWRfM=)

### Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6253428)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976007832)

![Central Scottsdale map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:gw_lE%60aijTsb%40%3FgMcPpBgn%40%7DWia%40%3FeP%7CW_%5DqBshPxP%7Di%40n%5Bia%40%3FapJtI%7BK%60xA%3FtIzK%3FlTsb%40lTuIte%40tIzKxi%40%3FrIzK%3Fvv%40%7EWnTsBzlPsIbP%7Dp%40iC%7DWnT%3Fb%7B%40vi%40%60%7B%40%3FdsDuIzKc_A%3FuIpGsBb%5DeMbP&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=62gJnAC6krgWApXscG-Nti6ZmQ4=)

### Central Scottsdale

While visiting Central Scottsdale, you might make a stop by sights like Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976007832)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=701380498943062016)

![Paradise Valley Village map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7D%7E%60lEnwmjTaBm%40rBaMkF%5By_%40JsBdAuAtBg%40jFch%40%40%40eO_DMgGA%3FrOulAMq%40eBgFwC%40zFk%60ACQaIeD%7BE%7DA_AqFGCzPsC%5BEkLmEF%40zKctA%3Fx%5CkaB%7CBaIte%40igAlLwZbKar%40lLq_AxyBhArfCb%40Ijt%40_UEChZ%60U%3Fi%40bqAvm%40%40d%40ku%40xl%40V%7BBrkB%60%40diBso%40CoFbAGk%40mCo%40m%5D%40%7B%40lB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=W5hwr-BpxKNDiAzx9LX583g2JQU=)

### Paradise Valley Village

While visiting Paradise Valley Village, you might make a stop by sights like Kierland Commons and Orange Tree Golf Course.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=701380498943062016)

## Top Mayo Clinic Hotel Reviews

![Crowne Plaza Phoenix Airport - PHX by IHG](//images.trvl-media.com/lodging/1000000/10000/6000/5903/5fc32fb8_y.jpg)

### Crowne Plaza Phoenix Airport - PHX by IHG

10/10 Excellent

"Great location, so close to the airport, makes traveling so much easier. Very clean location and most staff were amazing"

[](https://expedia.ca/Phoenix-Hotels-Crowne-Plaza-Phoenix-Phx-Airport.h5903.Hotel-Information)

![FOUNDRE Phoenix](//images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0_y.jpg)

### FOUNDRE Phoenix

10/10 Excellent

"Room was clean and staff were extremely accommodating "

[](https://expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information)

![Talking Stick Resort](//images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841_y.jpg)

### Talking Stick Resort

10/10 Excellent

"Rooms are great and the staff is definitely above the average. "

[](https://expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information)

![Hyatt Regency Phoenix](//images.trvl-media.com/lodging/1000000/10000/6900/6802/4fb94d6b_y.jpg)

### Hyatt Regency Phoenix

10/10 Excellent

"Everything was good. "

[](https://expedia.ca/Phoenix-Hotels-Hyatt-Regency-Phoenix.h6802.Hotel-Information)

![Hilton Garden Inn Phoenix Airport North](//images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/2eec66b2_y.jpg)

### Hilton Garden Inn Phoenix Airport North

10/10 Excellent

"Great airport shuttle service and great front desk service I’ll definitely stay here again"

[](https://expedia.ca/Phoenix-Hotels-Hilton-Garden-Inn-Phoenix-Airport-North.h2258085.Hotel-Information)

![SureStay Hotel by Best Western Phoenix Airport](//images.trvl-media.com/lodging/1000000/880000/874200/874177/0b333feb_y.jpg)

### SureStay Hotel by Best Western Phoenix Airport

10/10 Excellent

"Clean and safe room, shuttle to the airport. Exceptional service! "

[](https://expedia.ca/Phoenix-Hotels-SureStay-Hotel-By-Best-Western-Phoenix-Airport.h874177.Hotel-Information)

![Days Inn & Suites by Wyndham Mesa Near Phoenix](//images.trvl-media.com/lodging/1000000/10000/3800/3749/7b43a1e5_y.jpg)

### Days Inn & Suites by Wyndham Mesa Near Phoenix

10/10 Excellent

"Yes"

[](https://expedia.ca/Phoenix-Hotels-Days-Hotel-By-Wyndham-Mesa-Near-Phoenix.h3749.Hotel-Information)

![Hilton Phoenix Tapatio Cliffs Resort](//images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6_y.jpg)

### Hilton Phoenix Tapatio Cliffs Resort

10/10 Excellent

"The room was excellent! Very close to shopping. A very healthy place. I plan to return for an extended stay during the summer months. "

[](https://expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information)

![Arizona Grand Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/2800/2774/225d2d95_y.jpg)

### Arizona Grand Resort & Spa

10/10 Excellent

"View was great.. The upgrade to a suite was a pleasant surprise."

[](https://expedia.ca/Phoenix-Hotels-Arizona-Grand-Resort-Spa.h2774.Hotel-Information)

## Frequently asked questions

### What are the best hotels in Mayo Clinic that travellers recommend?

> [Sonesta Select Scottsdale at Mayo Clinic Campus](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) is a highly regarded hotel, receiving a great rating of 8.2 from guests. This property is not only conveniently located near the renowned Mayo Clinic, but it also boasts a range of amenities designed for both relaxation and productivity. Families and business travellers alike can enjoy the outdoor pool, hot tub, and comfortable meeting rooms, making it easy to unwind after a busy day or conduct successful meetings in a serene environment.

### What are the best family hotels in Mayo Clinic?

> [Sonesta Select Scottsdale at Mayo Clinic Campus](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) is an excellent choice for families visiting the area, boasting an excellent review score of 8.2. This property features connecting rooms, allowing families to stay close together while enjoying their own space, which is particularly beneficial for those with children.

### What are the best budget hotels in Mayo Clinic?

> [Sonesta Select Scottsdale at Mayo Clinic Campus](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) is a fantastic option for budget travellers seeking comfort and convenience. This hotel offers a warm and friendly setting, along with an impressive array of amenities to enhance your stay. Guests appreciate the free Wi-Fi throughout the property, making it easy to stay connected, and the outdoor pool and hot tub provide a superb spot to unwind after a day of exploring.

### Can I cancel my hotel reservation on Expedia?

> You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayo Clinic.

### How can I save on a Mayo Clinic hotel booking with Expedia?

> Before booking your Mayo Clinic hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia.

### How much is the nightly rate at a Mayo Clinic hotel?

> Hotel prices in Mayo Clinic often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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