Overall, the Roma Centro location is great! It's about a 15 min walk from Vatican City and 20 min from the Spanish Steps. Additionally, it is in the Prati neighborhood which is an upscale, contemporary area that's super walkable with lots of cute restaurants and cafes. However, since it is more upscale... expect to pay slightly higher prices. As for the hotel itself - staff is super helpful. I arrived early before the 3pm check-in and they were able to get me into a room right away. Also, I had an early morning flight and they were able to secure a car to pick up me up at 5:30a in the morning on my behalf. Minor watch outs... 1) the walls are pretty thin so expect to hear your neighbors and 2) as for cleanliness, it's clean, but not immaculate. When I first go into the room, I found a random hair on the sheets. Assuming it was left there when the sheets were being laundered.