Find Spa Hotels in Greenville, SC from CA $110

Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.

Hotel Hartness is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a couples treatment or massage at the onsite spa. Another popular spa hotel in Greenville is Grand Bohemian Lodge Greenville, Autograph Collection.

Among Expedia’s 567 accommodation options in Greenville, there are 8 spa hotels.

Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children’s Museum of the Upstate, and Falls Park on the Reedy. If you have some spare time during your trip, you might want to check out Bon Secours Wellness Arena and Greenville Zoo.

Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.